Week 1: Cancer basics
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Questions and Answers

List the 3 Tumor growth phases in order of occurence

1.Initiation 2.Promotion 3.Progression

What is a definition of cancer?

  • Mutations in genetic information of a cell that alters its function
  • Refers to a group of diseases characterized by uncontrolled cell division (correct)
  • A type of genetic disorder
  • Lump or mass of abnormal tissue cells
  • What is a neoplasm?

  • A benign tumor
  • A type of cancer
  • A lump or mass of abnormal tissue cells (correct)
  • A normal cell growth
  • What does cancer result from?

    <p>Mutations in genetic information of a cell that alters its function</p> Signup and view all the answers

    What happens in the ‘Initiation’ phase of tumor growth

    <p>Mutations of cells; this can be due to errors in cell division, inheritance from parents, or environmental exposure to damaging agents</p> Signup and view all the answers

    What happens in the ‘Promotion’ phase of tumor growth

    <p>Proliferation (the increase in # of daughter cells due to increased susceptibility to various promoters) &amp; angiogenesis (tumor increases in size once it develops its own blood supply by forming new blood vessels)</p> Signup and view all the answers

    What happens in the ‘Progression’ phase of tumor growth?

    <p>Invasion and metastasis (occurs when tumor invades a blood vessel or lymphatic system and migrates to a different site to form a distant tumor)</p> Signup and view all the answers

    What does it mean when a tumor has metastasized?

    <p>It means a tumor invades a blood vessel or lymphatic system and migrates to a different site to form a distant tumor</p> Signup and view all the answers

    Match term to definition

    <p>Proliferation = Increase in number of mutated daughter cells due to increased susceptibility to various promoters (growth factors, hormones etc) Angiogenesis = Tumor increases in size once it develops its own blood supply by forming new blood vessels Invasion = As the tumor continues to grow, it may start to invade surrounding tissues Metastasis = Occurs when the tumor invades a blood vessel or lymphatic system and migrates to a different site to form a distant tumor</p> Signup and view all the answers

    Put the 4 stages of cancer development in chronological order

    <p>1 = Hyperplasia 2 = Dysplasia 3 = In situ cancer 4 = Invasive cancer</p> Signup and view all the answers

    Name and explain the 4 stages of cancer development

    <ol> <li>Hyperplasia: cels divide more rapidly than normal 2. Dysplasia: cells change form 3. In situ cancer: cells stay in one place 4. Invasive cancer: cancer cells invade normal tissues and enter blood and lymph and/or metastases form at distant sites</li> </ol> Signup and view all the answers

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