Tumor Growth and Mouse Models
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Questions and Answers

According to the Skipper-Schabel-Wilcox model, how do tumors grow?

  • Quadratically: starts slow and then grows faster
  • Logarithmically: starts slow and then plateaus at the end (correct)
  • Exponentially: starts slow and then rapidly grows
  • Linearly: grows at a constant rate

    • According to the Log-kill Hypothesis, what happens when tumors are treated with chemotherapy?

  • The same amount of tumor is killed with each dose of chemotherapy regardless of tumor size (correct)
  • The tumor size decreases linearly with each dose of chemotherapy
  • The tumor size decreases quadratically with each dose of chemotherapy
  • The tumor size decreases exponentially with each dose of chemotherapy

    • What are the limitations of the Skipper-Schabel-Wilcox model?

  • It is not applicable for humans
  • The doubling time for tumors in reality is not constant
  • Tumors do not exhibit logarithmic growth
  • All of the above (correct)

    • According to the Gompertzian Growth model, how do tumors grow in humans?

    <p>Sigmoidally: starts slow, then becomes logarithmic and plateaus at the end</p> Signup and view all the answers

    How do tumor cells respond to chemotherapy according to the text?

    <p>The tumor cells become resistant to chemotherapy with each mutation</p> Signup and view all the answers

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