Tumor Antigens and Mutated Genes Quiz
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Questions and Answers

What is the concept of immune surveillance proposed by Macfarlane Burnet?

  • To grow tumors after they are formed
  • To activate external stimuli to kill tumor cells
  • To recognize and destroy transformed cells before they grow into tumors (correct)
  • To stimulate specific, adaptive immune responses
  • What evidence supports the concept of tumor immunity?

  • Lymphocyte proliferation in the bloodstream
  • Cancer risk decreases after immunosuppression
  • Tumors are always surrounded by red blood cells
  • Metastases regress after primary tumor removal (correct)
  • Why is it important to identify tumor antigens in humans?

  • To prevent immune responses
  • To cause antibody overproduction
  • To decrease NK cell presence in tumors
  • To use as components of tumor vaccines (correct)
  • Which statement accurately describes tumor-specific antigens?

    <p>Expressed on tumor cells but not on normal cells</p> Signup and view all the answers

    What is the function of the immune system in relation to tumors?

    <p>To recognize and destroy transformed cells before they grow into tumors</p> Signup and view all the answers

    What is observed in tumors regarding immune cell infiltrates?

    <p>Mononuclear cell infiltrates containing T lymphocytes, NK cells, and macrophages</p> Signup and view all the answers

    How do tumors stimulate immune responses?

    <p>By stimulating specific, adaptive immune responses</p> Signup and view all the answers

    What is the role of tumor antigens in immunotherapy?

    <p>Generate effector T cells for immunotherapy</p> Signup and view all the answers

    Why do immune responses frequently fail to prevent tumor growth?

    <p>Tumors can evade immune detection or suppression by producing inhibitory molecules</p> Signup and view all the answers

    What are the implications of recognizing and destroying transformed cells before they grow into tumors?

    <p>Preventing the formation of malignant tumors</p> Signup and view all the answers

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