10 Questions
What is the concept of immune surveillance proposed by Macfarlane Burnet?
To recognize and destroy transformed cells before they grow into tumors
What evidence supports the concept of tumor immunity?
Metastases regress after primary tumor removal
Why is it important to identify tumor antigens in humans?
To use as components of tumor vaccines
Which statement accurately describes tumor-specific antigens?
Expressed on tumor cells but not on normal cells
What is the function of the immune system in relation to tumors?
To recognize and destroy transformed cells before they grow into tumors
What is observed in tumors regarding immune cell infiltrates?
Mononuclear cell infiltrates containing T lymphocytes, NK cells, and macrophages
How do tumors stimulate immune responses?
By stimulating specific, adaptive immune responses
What is the role of tumor antigens in immunotherapy?
Generate effector T cells for immunotherapy
Why do immune responses frequently fail to prevent tumor growth?
Tumors can evade immune detection or suppression by producing inhibitory molecules
What are the implications of recognizing and destroying transformed cells before they grow into tumors?
Preventing the formation of malignant tumors
Test your knowledge on tumor antigens, mutated genes, and antigens of oncogenic viruses. Learn about tumor-associated antigens, products of mutated genes, and antigens associated with oncogenic viruses.
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