Podcast
Questions and Answers
Which drug specifically targets mycobacteria?
Which drug specifically targets mycobacteria?
- Isoniazid (correct)
- Streptomycin sulphate
- Kanamycin sulphate
- Rifampicin
Which drug is associated with hydrazides of isonicotinic acid?
Which drug is associated with hydrazides of isonicotinic acid?
- Ethambutol
- Ethionamide
- Isoniazid (correct)
- Rifampicin
Isoniazid has an antivitamin effect primarily against which vitamin?
Isoniazid has an antivitamin effect primarily against which vitamin?
- Vitamin C
- Vitamin B₁
- Vitamin D
- Vitamin B₆ (correct)
What is the mechanism of action of isoniazid?
What is the mechanism of action of isoniazid?
Which anti-tuberculosis drug is classified as an aminoglycoside antibiotic?
Which anti-tuberculosis drug is classified as an aminoglycoside antibiotic?
What mechanism does streptomycin use to combat mycobacterial infections?
What mechanism does streptomycin use to combat mycobacterial infections?
Which adverse effect is particularly associated with the use of streptomycin?
Which adverse effect is particularly associated with the use of streptomycin?
What is the mechanism of action of para-aminosalicylic acid (PAS)?
What is the mechanism of action of para-aminosalicylic acid (PAS)?
What principle of tuberculosis therapy helps in delaying mycobacterium resistance?
What principle of tuberculosis therapy helps in delaying mycobacterium resistance?
Flashcards
Isoniazid's mechanism of action
Isoniazid's mechanism of action
Isoniazid disrupts mycolic acid synthesis in mycobacteria.
Isoniazid's related class
Isoniazid's related class
Isoniazid is a hydrazide of isonicotinic acid, a specific type of drug.
Isoniazid's vitamin interaction
Isoniazid's vitamin interaction
Isoniazid interferes with Vitamin B6 metabolism.
Streptomycin's mechanism of action
Streptomycin's mechanism of action
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Streptomycin adverse effect
Streptomycin adverse effect
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PAS mechanism of action
PAS mechanism of action
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Combination therapy for TB
Combination therapy for TB
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Aminoglycoside antibiotic example
Aminoglycoside antibiotic example
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Mycobacterial-specific antibiotic
Mycobacterial-specific antibiotic
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Rifampicin's presence as antibiotic
Rifampicin's presence as antibiotic
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Study Notes
Tuberculosis Drugs
- Specific Mycobacterial Action: Isoniazid is a drug that only affects mycobacteria.
- Isoniazid & Hydrazide Relationship: Isoniazid is related to hydrazides.
- Anti-Vitamin Activity: Isoniazid is an anti-vitamin B complex drug.
- Isoniazid Mechanism: Inhibits mycolic acid synthesis.
- Streptomycin Mechanism: Disrupts protein synthesis at the ribosome level.
- Streptomycin Side Effect: Hearing loss.
- PAS Mechanism: Competes with para-aminobenzoic acid (PABA).
- Multi-Drug Therapy (MDR): Using multiple drugs to treat tuberculosis can slow the development of drug resistance.
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Description
Explore the mechanisms and actions of drugs used in the treatment of tuberculosis, focusing on Isoniazid, Streptomycin, and PAS. Learn how these medications interact with mycobacterial processes and the importance of multi-drug therapy in preventing resistance.
