Trypanosoma cruzi and Chagas' Disease Quiz
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Questions and Answers

How is Trypanosoma cruzi primarily transmitted to humans?

  • Through direct contact with an infected person
  • Through ingestion of contaminated food and water
  • Through the bite of infected mosquitoes
  • Through the feces of triatomine bugs (correct)
  • What is the name of the disease caused by Trypanosoma cruzi in South America?

  • Dengue fever
  • Chagas' disease (correct)
  • Malaria
  • Lyme disease
  • Where do trypomastigotes enter the host's body after being released by the triatomine bug?

  • Through the skin or mucosal membranes (correct)
  • Through the respiratory system
  • Through the urinary system
  • Through the digestive system
  • How do trypomastigotes transform into infective metacyclic trypomastigotes inside the triatomine bug?

    <p>By multiplying rapidly in the midgut</p> Signup and view all the answers

    Apart from triatomine bugs, in what other ways can Trypanosoma cruzi be transmitted?

    <p>Through blood transfusions and organ transplantation</p> Signup and view all the answers

    What is the infective stage parasite found in the blood and body fluids?

    <p>Trypomastiogate stages</p> Signup and view all the answers

    Where are the amastigotes found in chronic infection?

    <p>In macrophages, nerve, and muscle cells</p> Signup and view all the answers

    What causes the heart to hypertrophy in chronic infection?

    <p>Parasites in heart muscle</p> Signup and view all the answers

    What is the common habitat for the Triatomid bugs that transmit T.cruzi?

    <p>Palm branch roofing and wattle and daub walls</p> Signup and view all the answers

    What is the issue with detecting Chagas disease using blood antibodies?

    <p>It can take 10 years or more</p> Signup and view all the answers

    What is the primary habitat for Triatomid bugs that transmit T.cruzi?

    <p>Palm trees</p> Signup and view all the answers

    How does Chagas disease primarily spread to humans?

    <p>Through the bite of infected Triatomid bugs</p> Signup and view all the answers

    What is the main issue with detecting Chagas disease using blood antibodies?

    <p>The presence of blood antibodies does not necessarily indicate current infection</p> Signup and view all the answers

    What is the potential similarity between Chagas disease and AIDS as mentioned in the text?

    <p>Both diseases have a long asymptomatic phase</p> Signup and view all the answers

    What is the function of the drugs posaconazole and ravuconazole in relation to Chagas disease?

    <p>They inhibit a key enzyme in sterol synthesis of the parasites</p> Signup and view all the answers

    What is the primary mode of transmission for Trypanosoma cruzi?

    <p>Through blood transfusions, organ transplantation, or transplacental transmission</p> Signup and view all the answers

    Where do trypomastigotes invade the host's body upon being released by the triatomine bug?

    <p>Through direct penetration of the skin</p> Signup and view all the answers

    How do trypomastigotes transform into infective metacyclic trypomastigotes inside the triatomine bug?

    <p>By differentiating into epimastigotes</p> Signup and view all the answers

    Where are amastigotes found in chronic infection with Trypanosoma cruzi?

    <p>In cardiac muscle cells and smooth muscle tissue</p> Signup and view all the answers

    What causes heart hypertrophy in chronic infection with Trypanosoma cruzi?

    <p>Direct invasion of the heart by trypomastigotes</p> Signup and view all the answers

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