5 Questions
What is the role of TRPS1 in breast cancer?
TRPS1 functions as an essential regulator for the growth and differentiation of normal mammary epithelial cells and may be involved in the development of breast cancer.
What did Radvanyi et al. find in their microarray analysis of breast tumor samples?
They identified a group of 15 genes overexpressed in breast cancer, including TRPS1.
What is the consequence of loss of the TRPS1 gene?
It can cause trichorhinophalangeal syndrome, a hereditary autosomal dominant disorder characterized by distinctive facial features and bone and joint malformations.
What did Radvanyi et al. initially believe about TRPS1 in relation to breast cancer?
They thought that TRPS1 was a suppressor gene for breast cancer and a regulator of luminal progenitor cells.
What is the latest identified marker in the GATA family of zinc finger transcription factors?
TRPS1
Test your knowledge of TRPS1, a newly identified breast marker with high sensitivity for TNBC. Learn about its role in the GATA family of zinc finger transcription factors and its critical role in the development of cartilage, bone, kidney, and hair follicles.
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