Trigeminal Neuropathy in Dogs

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Questions and Answers

Which of the following is most commonly affected by trigeminal neuropathy?

  • German Shepherd
  • Poodle
  • Golden Retriever (correct)
  • Dachshund

Which clinical sign is typically associated with trigeminal neuropathy in dogs?

  • Increased energy
  • Increased appetite
  • Dropped jaw (correct)
  • Excessive barking

What percentage of dogs with trigeminal neuropathy exhibit sensory deficits?

  • 50%
  • 75%
  • 25% (correct)
  • 10%

What diagnostic tool is recommended to rule out tumors as a cause of trigeminal neuropathy?

<p>MRI (D)</p> Signup and view all the answers

How long does it typically take for dogs with idiopathic trigeminal neuropathy to recover?

<p>Within 3 weeks (A)</p> Signup and view all the answers

What is a common clinical presentation in dogs affected by nerve sheath tumors of CNV?

<p>Unilateral muscle atrophy (C)</p> Signup and view all the answers

Which of the following is a possible treatment option for nerve sheath tumors of CNV?

<p>Radiation therapy (D)</p> Signup and view all the answers

What is a typical characteristic of idiopathic facial nerve paralysis in dogs?

<p>Rapid onset with no identifiable cause (A)</p> Signup and view all the answers

Which breed is predisposed to idiopathic facial nerve paralysis?

<p>Cocker Spaniel (C)</p> Signup and view all the answers

What clinical sign is associated with idiopathic facial nerve paralysis?

<p>Increased salivation (A)</p> Signup and view all the answers

Approximately what percentage of dogs with idiopathic facial nerve paralysis will have the other side of their face affected months later?

<p>50% (D)</p> Signup and view all the answers

Which of the following diagnostic tests is helpful when diagnosing idiopathic facial nerve paralysis?

<p>Schirmer tear test (D)</p> Signup and view all the answers

What type of nystagmus is characteristic of central vestibular disease?

<p>Vertical (B)</p> Signup and view all the answers

Which of the following is a clinical sign of vestibular disease?

<p>Head tilt (A)</p> Signup and view all the answers

What is the discharge rate of the peripheral vestibular system at rest?

<p>100 Hz (D)</p> Signup and view all the answers

Which of the following structures is part of the central vestibular system?

<p>Vestibular nuclei (D)</p> Signup and view all the answers

Which cranial nerves have a connection to the medial longitudinal fasciculus (MFL)?

<p>CN III, IV, VI (C)</p> Signup and view all the answers

In otitis media/interna, how does infection typically reach the bulla tympanica?

<p>Via the ear canal (D)</p> Signup and view all the answers

Which bacterium is commonly associated with otitis media/interna?

<p>Staphylococcus aureus (C)</p> Signup and view all the answers

Which of the following is a typical clinical sign of otitis media/interna?

<p>Head tilt (B)</p> Signup and view all the answers

Which diagnostic tool is commonly used to assess the bulla in cases of suspected otitis media/interna?

<p>Bulla series (A)</p> Signup and view all the answers

What does myringotomy involve in the diagnosis of otitis media/interna?

<p>Incision of the tympanic membrane for sample collection (C)</p> Signup and view all the answers

What long-term treatment option can be prescribed for otitis media/interna?

<p>Antibiotics (D)</p> Signup and view all the answers

What is the typical signalment for dogs that have idiopathic vestibular syndrome?

<p>Old (D)</p> Signup and view all the answers

What is the most common clinical sign for idiopathic vestibular syndrome in dogs?

<p>Head tilt (A)</p> Signup and view all the answers

What is a key characteristic of the clinical signs associated with idiopathic vestibular syndrome?

<p>Peracute to acute onset (D)</p> Signup and view all the answers

Which of the following clinical signs would NOT generally be associated with idiopathic vestibular syndrome?

<p>Facial nerve paralysis (D)</p> Signup and view all the answers

What underlying pathogenic cause is associated with idiopathic vestibular syndrome?

<p>Unclear (D)</p> Signup and view all the answers

How long does it typically take for a dog to recover from idiopathic vestibular syndrome?

<p>Days to weeks (A)</p> Signup and view all the answers

Which of the following should be ruled out when diagnosing idiopathic vestibular syndrome?

<p>All of the above (D)</p> Signup and view all the answers

In addition to supportive care, what medication can be used to help a dog with idiopathic vestibular syndrome?

<p>Sedation (C)</p> Signup and view all the answers

What is the most common cause for cranial nerve disorders?

<p>Otitis media (B)</p> Signup and view all the answers

Which of the following best represents the general prognosis for properly diagnosed and treated cranial nerve disorders?

<p>Good outcomes (B)</p> Signup and view all the answers

In the context of nerve sheath tumors affecting cranial nerve V (CNV), which histological subtype indicates a tumor originating from the myelin-producing cells?

<p>Neurilemmoma (D)</p> Signup and view all the answers

Which of these conditions is least likely to be included when establishing a differential diagnosis for canine idiopathic vestibular syndrome?

<p>Geriatric onset (D)</p> Signup and view all the answers

If a dog presents with acute onset of head tilt, ataxia, and spontaneous nystagmus, differentiating between peripheral and central vestibular disease is crucial. Which of the following clinical signs is MOST indicative of central vestibular disease rather than peripheral?

<p>Vertical nystagmus irrespective of head position (C)</p> Signup and view all the answers

In an 8-year-old Maltese presenting with signs suggestive of a nerve sheath tumor of CN V, which advanced imaging modality, combined with specific contrast enhancement protocols, would offer the highest sensitivity for visualizing the extent of tumor invasion along the trigeminal nerve pathway?

<p>High-resolution MRI with contrast-enhanced T1-weighted fat-suppressed sequences (D)</p> Signup and view all the answers

What type of nystagmus is commonly associated with vestibular disease?

<p>Any of the above (D)</p> Signup and view all the answers

Which of the following is a potential etiology for trigeminal neuropathy in dogs?

<p>Idiopathic causes (C)</p> Signup and view all the answers

What clinical presentation is more commonly observed in cases of otitis media/interna?

<p>Sudden and progressive onset of clinical signs (C)</p> Signup and view all the answers

Besides supportive care, which medication types are typically used in the treatment of idiopathic vestibular syndrome?

<p>Sedatives (A)</p> Signup and view all the answers

What is a diagnostic tool used to evaluate the bulla tympanica for otitis media/interna?

<p>Bulla series radiographs (B)</p> Signup and view all the answers

Which of the following is a typical clinical sign observed in dogs affected by trigeminal neuropathy?

<p>Dropped jaw (A)</p> Signup and view all the answers

Which of the following is a possible route of bacterial infection leading to otitis media/interna?

<p>Via the ear canal (D)</p> Signup and view all the answers

What diagnostic test involves obtaining samples for cytological analysis and culture sensitivity when diagnosing otitis media/interna?

<p>Myringotomy (D)</p> Signup and view all the answers

What is the underlying cause of idiopathic vestibular syndrome?

<p>Unknown (C)</p> Signup and view all the answers

In cases of nerve sheath tumors affecting CN V, which clinical sign is more indicative of tumor progression rather than inflammation or idiopathic neuropathy?

<p>Chronic, progressive unilateral muscle atrophy (A)</p> Signup and view all the answers

Which imaging modality provides superior detail for assessing the extent of nerve sheath tumors of CNV?

<p>MRI (B)</p> Signup and view all the answers

What differentiates central from peripheral vestibular disease based on the type of nystagmus observed?

<p>Central disease may present with vertical nystagmus. (A)</p> Signup and view all the answers

Considering the anatomical course of the facial nerve, which clinical sign, if present alongside idiopathic facial nerve paralysis, would suggest potential involvement of the vestibular system?

<p>Head tilt (B)</p> Signup and view all the answers

Which of the following characteristics of nystagmus would be MOST concerning for central vestibular disease rather than peripheral vestibular disease in a canine patient?

<p>Vertical nystagmus that persists regardless of head position. (A)</p> Signup and view all the answers

A veterinary neurologist is evaluating a dog with suspected idiopathic trigeminal neuropathy. Electromyography (EMG) is performed on the muscles of mastication. What EMG finding would be MOST consistent with this diagnosis in the acute phase?

<p>Normal motor unit potentials in all muscles tested. (B)</p> Signup and view all the answers

What is the primary sensory function of the trigeminal nerve (CNV)?

<p>Sensory function of the face (C)</p> Signup and view all the answers

Why does bilateral trigeminal neuropathy typically result in a dropped jaw in dogs?

<p>The muscles on both sides of the jaw are weakened, preventing closure. (A)</p> Signup and view all the answers

Which aspect of the eating process is most affected in dogs with a dropped jaw due to trigeminal neuropathy?

<p>Phase one, involving the ability to hold food in the mouth (D)</p> Signup and view all the answers

Why is dehydration a significant concern in dogs with trigeminal neuropathy?

<p>They cannot properly lap up or hold water in their mouths. (D)</p> Signup and view all the answers

How are sympathetic fibers connected to the trigeminal nerve, leading to Horner's syndrome in some cases of trigeminal neuropathy?

<p>Sympathetic fibers travel along the carotid artery and then join the trigeminal nerve. (D)</p> Signup and view all the answers

Which diagnostic imaging modality is most useful for identifying nerve sheath tumors affecting the trigeminal nerve?

<p>MRI (B)</p> Signup and view all the answers

What is the primary focus of treatment for idiopathic trigeminal neuropathy?

<p>Supportive care (C)</p> Signup and view all the answers

How can owners provide hydration to dogs with trigeminal neuropathy that are having difficulty drinking?

<p>Applying water to the larynx/pharynx with a syringe. (D)</p> Signup and view all the answers

What is the significance of positional vestibular strabismus and vertical nystagmus in the diagnosis of trigeminal neuropathy?

<p>They are not associated with trigeminal neuropathy and may indicate a different underlying issue. (D)</p> Signup and view all the answers

What is the significance of muscle atrophy affecting the muscles of mastication, such as the temporal and masseter muscles?

<p>It indicates lower motor neuron disease and could suggest involvement of CNV. (B)</p> Signup and view all the answers

Why is surgical resection of nerve sheath tumors affecting cranial nerve V (CNV) considered difficult?

<p>It is located deep in the ventral approach and would hit major difficult structures. (A)</p> Signup and view all the answers

Aside from motor and sensory functions, what other function can be affected by facial nerve (CN VII) dysfunction?

<p>Tear production. (C)</p> Signup and view all the answers

What clinical sign is LEAST likely to be associated with facial nerve (CN VII) paralysis?

<p>Increased salivation (C)</p> Signup and view all the answers

Why is an otitis media-interna considered an important differential diagnosis for facial nerve paralysis?

<p>The facial nerve runs through the bulla tympanica and can be affected by infection. (B)</p> Signup and view all the answers

What is the typical timeframe for improvement in cases of idiopathic facial nerve paralysis?

<p>2-3 months (C)</p> Signup and view all the answers

What is an important consideration when managing dogs with facial nerve paralysis to prevent corneal damage?

<p>Lubricating the eye (A)</p> Signup and view all the answers

If a dog recovers from facial nerve paralysis and then develops the same condition on the opposite side months later, what is the likely explanation?

<p>It is an expected occurrence of the idiopathic form of the disease, which can be bilateral. (D)</p> Signup and view all the answers

What is the function of the semicircular ducts within the vestibular system?

<p>Sensing rotation (B)</p> Signup and view all the answers

Which of the following is an effective method to accentuate nystagmus during a neurological examination?

<p>Changing the patient's position (A)</p> Signup and view all the answers

What combination of clinical signs is most indicative of peripheral vestibular disease rather than central vestibular disease?

<p>Head tilt, vestibular ataxia, normal proprioception, and Horner's syndrome (C)</p> Signup and view all the answers

What is the most likely method by which bacteria reach the middle ear in cases of otitis media?

<p>Through the external ear canal. (A)</p> Signup and view all the answers

What diagnostic imaging modality is best for visualizing the inner ear organs (succulus, utriculus, cochlea) and detecting changes associated with otitis interna?

<p>MRI (A)</p> Signup and view all the answers

Which of the following is a major advantage of using ultrasound to diagnose otitis media?

<p>It's non-invasive. (D)</p> Signup and view all the answers

What is the main therapeutic approach for managing cases of idiopathic vestibular syndrome?

<p>Supportive care (C)</p> Signup and view all the answers

What differentiates idiopathic vestibular syndrome from other vestibular conditions?

<p>Paracute onset and lack of cranial nerve deficits. (C)</p> Signup and view all the answers

Which of the following would be an appropriate medication to administer to a dog suffering from idiopathic vestibular syndrome to reduce nausea?

<p>Meclizine (B)</p> Signup and view all the answers

What is the typical expected timeframe for seeing improvement with supportive care in cases of idiopathic vestibular syndrome?

<p>Within 24 to 72 hours (C)</p> Signup and view all the answers

Which clinical sign helps differentiate otitis media/interna from idiopathic vestibular syndrome?

<p>Horner's syndrome (B)</p> Signup and view all the answers

What is a common long-term treatment strategy for otitis media/interna when medical management is insufficient?

<p>Surgical intervention (D)</p> Signup and view all the answers

Why is it important to rule out conditions like otitis media/interna, tumors, and strokes when diagnosing idiopathic vestibular syndrome?

<p>Because these conditions can present with similar clinical signs (D)</p> Signup and view all the answers

In companion animals, what are tumors arising from nerve tissues generally classified as?

<p>Nerve sheath tumors (D)</p> Signup and view all the answers

What should be the next diagnostic step if a 10-year-old dog has a acute onset of having a dropped food, and vestibular signs (positional vestibular strabismus and nystagmus)?

<p>Careful neurological exam (A)</p> Signup and view all the answers

Which of the following is most common cranial nerve disorder?

<p>Peripheral vestibular disease (B)</p> Signup and view all the answers

What is an important aspect to consider when assessing the bulla with a CT scan?

<p>The bullae are filled with air. (B)</p> Signup and view all the answers

What is thought to be the etiology of vestibular disease in older dogs?

<p>Etiology unclear (B)</p> Signup and view all the answers

When performing a spinal fuild tap on a dog, what finding would indicate lymphoma?

<p>Lymphoblasts (D)</p> Signup and view all the answers

Which of the following conditions typically shows improvement in 24 to 72 hours?

<p>Idiopathic vestibular syndrome (D)</p> Signup and view all the answers

In dogs with trigeminal neuropathy and concurrent Horner's syndrome, what anatomical relationship explains the connection between cranial nerve V and the sympathetic fibers?

<p>Sympathetic fibers travel along the carotid artery and 'jump' onto the trigeminal nerve near its ganglion. (C)</p> Signup and view all the answers

Besides nerve sheath tumors, what are other important differential diagnoses to consider when presented with a dog showing clinical signs of trigeminal neuropathy?

<p>Neosporosis and lymphoma (D)</p> Signup and view all the answers

What is the primary reason for emphasizing hydration in the supportive care of dogs with trigeminal neuropathy?

<p>Dogs with a dropped jaw have difficulty drinking, leading to rapid dehydration. (D)</p> Signup and view all the answers

Why is it important to avoid using a full neurological exam as a shortcut, even if you see a dropped jaw in dogs?

<p>Other conditions, such as lymphoma, can present with similar signs, so a more thorough assessment is necessary for correct diagnosis. (A)</p> Signup and view all the answers

Why might surgical resection of nerve sheath tumors affecting the trigeminal nerve be considered difficult?

<p>The location of the nerve requires a deep ventral approach, risking damage to vital structures. (A)</p> Signup and view all the answers

What is the significance of observing positional vestibular strabismus and vertical nystagmus during a neurological examination?

<p>They indicate involvement of the vestibular system, suggesting a central or multifocal disease process rather than isolated trigeminal neuropathy. (B)</p> Signup and view all the answers

What is one of the main differences in the underlying signs that can help differentiate between dogs affected by trigeminal neuropathy compared to nerve sheath tumors?

<p>The signs associated with nerve sheath tumors tend to be progressive and unilateral, whereas trigeminal neuropathy is often bilateral. (C)</p> Signup and view all the answers

What is an important aspect to consider when managing dogs with facial nerve paralysis to prevent corneal damage?

<p>Facial nerve paralysis can affect tear production and eyelid closure, so lubrication of the eye is necessary to prevent corneal ulceration. (A)</p> Signup and view all the answers

What are the possible etiologies for a facial nerve paralysis?

<p>Idiopathic, Otitis media interna, Tumors (A)</p> Signup and view all the answers

What makes otitis media-interna an important differential diagnosis for facial nerve paralysis?

<p>The facial nerve passes in close proximity to or through the bulla tympanica; infection can affect said nerve. (C)</p> Signup and view all the answers

What is the primary function of the semicircular ducts within the vestibular system?

<p>Sensing rotation (B)</p> Signup and view all the answers

If spontaneous nystagmus is not readily apparent during a neurological examination, what technique can be used to accentuate or trigger it?

<p>Changing the position of the head (C)</p> Signup and view all the answers

What clinical signs, when observed together, are MOST suggestive of peripheral vestibular disease rather than central vestibular disease?

<p>Head tilt, vestibular ataxia, horizontal nystagmus, Horner's syndrome. (B)</p> Signup and view all the answers

What is the most likely route by which bacteria reach the middle ear in cases of otitis media?

<p>Ascending infection from the external ear canal or via the Eustachian tube (C)</p> Signup and view all the answers

What is a major advantage of using an MRI to diagnose otitis media/interna compared to a CT scan or radiographs?

<p>It is superior for visualizing the inner ear organs and detecting changes associated with otitis interna. (B)</p> Signup and view all the answers

How does ultrasound aid in the diagnosis of otitis media?

<p>Ultrasound allows for evaluation of the tympanic bulla contents. (C)</p> Signup and view all the answers

What is the most important aspect to consider when managing cases of idiopathic vestibular syndrome?

<p>Providing supportive care and ruling out other causes (A)</p> Signup and view all the answers

What is a common characteristic of idiopathic vestibular syndrome?

<p>Rapid improvement within 24 to 72 hours (D)</p> Signup and view all the answers

Which clinical sign should be absent with uncomplicated geriatric vestibular syndrome? Select the MOST appropriate answer.

<p>Facial nerve paralysis or Horner's syndrome (C)</p> Signup and view all the answers

What type of medication is most appropriate to administer to a dog suffering from idiopathic vestibular syndrome to reduce nausea?

<p>Antihistamine (Meclizine) (C)</p> Signup and view all the answers

What should be the next step if a 10-year-old dog has an acute onset of neurological deficits (dropped food, positional vestibular strabismus, and nystagmus)?

<p>Conduct advanced imaging such as an MRI or CT scan. (D)</p> Signup and view all the answers

If a dog recovers from facial nerve paralysis and then develops a similar condition on the opposite side months later, which of the following explanations is most likely?

<p>Idiopathic facial nerve paralysis can occur bilaterally, even with a delay between episodes. (B)</p> Signup and view all the answers

Which diagnostic imaging modality is MOST suitable for visualizing the tympanic bulla?

<p>CT scan (B)</p> Signup and view all the answers

Why are medium to larger dog breeds more frequently affected by geriatric vestibular syndrome?

<p>The reason as to why larger breeds are more frequently affected is currently unknown. (D)</p> Signup and view all the answers

In the vast majority of isolated coranial nerve deficits, what is the recommended treatment?

<p>Supportive care (C)</p> Signup and view all the answers

What should be included as an important rule out for geriatric vestibular syndrome?

<p>Otitis media interna (A)</p> Signup and view all the answers

What is the expected prognosis regarding appropriate diagnosis and treatment for cranial nerve disorders?

<p>Often self limiting (A)</p> Signup and view all the answers

In a dog presenting with trigeminal neuropathy and exhibiting a dropped jaw, what is the primary reason for the difficulty in forming a food bolus?

<p>Inability to adequately close the mouth due to bilateral motor dysfunction (A)</p> Signup and view all the answers

If a dog is diagnosed with trigeminal neuropathy and exhibits hypersalivation, what is the most likely explanation for this clinical sign?

<p>Difficulty swallowing saliva due to the dropped jaw (B)</p> Signup and view all the answers

Why is dehydration a critical concern in dogs with trigeminal neuropathy?

<p>The dropped jaw makes it difficult for the dog to drink, thus resulting in rapid dehydration (B)</p> Signup and view all the answers

In cases of trigeminal neuropathy, the sympathetic fibers 'borrow' cranial nerve V to reach the eye. Which artery do they initially follow before associating with the trigeminal nerve?

<p>Carotid artery (D)</p> Signup and view all the answers

When diagnosing trigeminal neuropathy, what is the primary reason for performing an MRI?

<p>To rule out other conditions such as nerve sheath tumors or lymphoma (D)</p> Signup and view all the answers

What is the general consensus regarding the use of prednisone in treating idiopathic trigeminal neuropathy?

<p>Prednisone is generally not recommended as it does not alter the outcome or shorten the recovery time (D)</p> Signup and view all the answers

When providing supportive care for a dog with trigeminal neuropathy, why is it recommended to administer water via a syringe directed towards the larynx/pharynx?

<p>The dog can still swallow and this ensures proper hydration despite difficulty with normal drinking (A)</p> Signup and view all the answers

In instances of trigeminal neuropathy where Horner's syndrome is concurrently observed, which anatomical relationship explains the connection between cranial nerve V and the sympathetic fibers?

<p>Postganglionic sympathetic fibers accompany the carotid artery and 'hitchhike' on cranial nerve V to reach the eye. (C)</p> Signup and view all the answers

What is the most critical aspect of supportive care for dogs diagnosed with trigeminal neuropathy?

<p>Ensuring adequate hydration through various methods. (C)</p> Signup and view all the answers

In cases of nerve sheath tumors affecting the trigeminal nerve (CN V), why might a dropped jaw not be observed?

<p>Tumors affecting CN V are always unilateral, and the unaffected side can compensate. (A)</p> Signup and view all the answers

Why is surgical resection of nerve sheath tumors affecting cranial nerve V (CNV) considered a challenging procedure?

<p>The surgical approach requires accessing deep ventral structures, risking damage to critical anatomical structures. (B)</p> Signup and view all the answers

When presented with a dog exhibiting a dropped jaw and suspected trigeminal neuropathy, why should a full neurological exam be performed, rather than relying solely on the presence of this clinical sign for diagnosis?

<p>To identify additional neurological deficits (positional vestibular strabismus and vertical nystagmus), suggesting other underlying conditions such as lymphoma. (A)</p> Signup and view all the answers

In cases of facial nerve paralysis secondary to otitis media/interna, what is the most direct mechanism by which the facial nerve function is compromised?

<p>Inflammation and edema from the infection directly affect the facial nerve as it courses through or near the bulla tympanica. (D)</p> Signup and view all the answers

If nystagmus is not readily apparent during a neurological examination for suspected vestibular disease, what provocative technique can be used to help identify positional nystagmus?

<p>Changing the patient's head position or flipping the dog upside down to better visualize the nystagmus. (C)</p> Signup and view all the answers

What is the significance of lubricating the eye in dogs with facial nerve paralysis?

<p>Facial paralysis can impair eyelid closure, leading to corneal dryness and potential ulceration, requiring lubrication. (C)</p> Signup and view all the answers

Which part of the vestibular system is primarily responsible for sensing rotational movements of the head?

<p>Semicircular ducts (B)</p> Signup and view all the answers

A cat is presented with vestibular signs. During the neurological examination, you do not observe nystagmus initially. What technique can be used to better assess for nystagmus?

<p>Change the position of the head (C)</p> Signup and view all the answers

What is the primary route by which infections typically spread to the middle ear, leading to otitis media?

<p>Ascending infection via the Eustachian tube (A)</p> Signup and view all the answers

What are the major advantage of using ultrasound to aid in the diagnosis of otitis media?

<p>It's non-invasive because it can be performed without anesthesia and offers quick results. (C)</p> Signup and view all the answers

What is the recommended approach for managing most cases of idiopathic vestibular syndrome?

<p>Supportive care, including anti-nausea medications and IV fluids if needed. (C)</p> Signup and view all the answers

A dog is diagnosed with idiopathic vestibular syndrome. What would be an appropriate medication to administer to help reduce nausea?

<p>Meclizine (D)</p> Signup and view all the answers

Why is it important to rule out specific conditions when diagnosing idiopathic vestibular syndrome?

<p>To identify treatable causes of vestibular signs, altering the course of treatment (A)</p> Signup and view all the answers

What is the common term used in veterinary medicine for tumors arising from nerve tissues?

<p>Nerve Sheath Tumors (A)</p> Signup and view all the answers

Which of the following would warrant further diagnostics, such as advanced imaging or a spinal fluid tap, to rule out more serious differentials like neoplasia or inflammatory disease?

<p>A 10-year-old dog with acute onset vestibular signs (positional vestibular strabismus and nystagmus) along with a reluctance to eat (D)</p> Signup and view all the answers

When assessing the bulla with a CT scan for potential otitis media/interna, what is an important aspect to consider?

<p>The presence of fluid or soft tissue densities within the bulla (C)</p> Signup and view all the answers

What is a proposed etiology of idiopathic vestibular syndrome in older dogs that is similar to Meniere's disease in humans?

<p>Viral neuritis of the vestibulocochlear nerve (A)</p> Signup and view all the answers

Following otic causes, what disease should be considered when a geriatric dog presents for acute vestibular signs?

<p>Idiopathic vestibular syndrome (A)</p> Signup and view all the answers

What clinical sign of facial nerve (CN VII) dysfunction would suggest the nerved innervating the salivary glands is affected?

<p>Drooling (C)</p> Signup and view all the answers

What clinical sign of otitis media/interna may indicate the facial nerves are implicated?

<p>Dry eye (D)</p> Signup and view all the answers

In order to manage a corneal ulcer effectively, what needs to happen?

<p>Lubricate the eye (A)</p> Signup and view all the answers

During the neurological examination for vestibular system issues, how can you trigger a nystagmus?

<p>Flip dog upside down (C)</p> Signup and view all the answers

What key factor(s) can help differentiate between central and peripheral vestibular disease?

<p>Proprioceptive function tests (B)</p> Signup and view all the answers

After assessing a cat that presents with a head tilt tot he right side and has a right-sided Horner's with horizontal nystagmus, what is your diagnosis?

<p>Peripheral (C)</p> Signup and view all the answers

To help support a medical management plan, how long should antibiotics be admnistered?

<p>Long-term treatments (C)</p> Signup and view all the answers

In companion animals what age is common for idiopathic vestibular syndrome to appear?

<p>Dogs are often more than 10 years of age (D)</p> Signup and view all the answers

What clinical sign during the exam is NOT common in Idiopathic vestibular syndrome?

<p>Facial nerve paralysis (A)</p> Signup and view all the answers

How can you increase the likelihood of seeing nystagmus on a dog?

<p>Flip over (A)</p> Signup and view all the answers

Which of the following treatment options is NOT as interventional as the others?

<p>Medication (@)</p> Signup and view all the answers

Most cranial nerve disorders are treated with supportive care; what disorder involves interventional procedures?

<p>Otitis (A)</p> Signup and view all the answers

Loss of muscle mass is a typical finding of lower motor neuron disease. What is innervated when there is a loss of muscle mass?

<p>Muscle of mastication (D)</p> Signup and view all the answers

After how long can you see an improvement with supportive care of geriatric vestibular syndrome?

<p>2-3 Days (A)</p> Signup and view all the answers

In trigeminal neuropathy, why is it critical to address dehydration quickly?

<p>Dogs with a dropped jaw have difficulty drinking, so they dehydrate quickly. (A)</p> Signup and view all the answers

When presented with a dog exhibiting a dropped jaw and suspected trigeminal neuropathy, why is it important to perform a complete neurological exam?

<p>To ensure a correct diagnosis, as other conditions can cause similar signs, and to identify any additional neurological deficits. (B)</p> Signup and view all the answers

In cases of nerve sheath tumors affecting the trigeminal nerve (CN V), why might a dropped jaw not always be observed?

<p>The tumor may only affect one side of the nerve, and the contralateral side can compensate. (C)</p> Signup and view all the answers

If spontaneous nystagmus is not readily apparent during a neurological examination for suspected vestibular disease, what provocative technique can be used to help identify positional nystagmus?

<p>Change the patient's head position, such as lifting the head or flipping the dog upside down. (C)</p> Signup and view all the answers

What is a common hallmark of otitis media/interna?

<p>All the above are common. (C)</p> Signup and view all the answers

In order to manage a corneal ulcer effectively due to facial nerve paralysis, what needs to happen?

<p>Lubricating the eye and monitoring for secondary complications. (A)</p> Signup and view all the answers

What is the common signalment/age for idiopathic vestibular syndrome?

<p>Geriatric. (A)</p> Signup and view all the answers

During a neurological exam of a dog with vestibular signs, what should you do to see nystagmus?

<p>Reposition the head to see if it appears. (B)</p> Signup and view all the answers

A dog presents with a dropped jaw, hypersalivation, and difficulty eating. While trigeminal neuropathy is suspected, what additional clinical sign would warrant further investigation to rule out nerve sheath tumor involvement, rather than idiopathic neuropathy?

<p>Unilateral muscle atrophy of the temporalis and masseter muscles. (D)</p> Signup and view all the answers

When differentiating between peripheral and central vestibular disease, what is the significance of proprioceptive deficits?

<p>Proprioceptive deficits are more commonly associated with central vestibular disease. (A)</p> Signup and view all the answers

In a dog presenting with acute vestibular signs, including head tilt and nystagmus, which of the following historical or clinical findings would make idiopathic vestibular syndrome less likely, prompting further investigation for other causes?

<p>Concurrent facial nerve paralysis or Horner’s syndrome. (C)</p> Signup and view all the answers

A veterinary technician is educating an owner about supportive care for a dog diagnosed with idiopathic trigeminal neuropathy. Which of the following instructions is MOST crucial to emphasize to prevent a life-threatening complication?

<p>Providing adequate hydration through various methods. (A)</p> Signup and view all the answers

When performing advanced imaging (CT or MRI) to assess the bulla tympanica for potential otitis media/interna, what is the MOST important factor to consider for accurate interpretation?

<p>The presence of fluid or soft tissue within the bulla. (B)</p> Signup and view all the answers

Which of the following is the MOST consistent clinical sign associated with nerve sheath tumors of cranial nerve V (CNV)?

<p>Unilateral muscle atrophy of the temporalis and masseter muscles (C)</p> Signup and view all the answers

What is the BEST initial treatment option for trigeminal neuritis?

<p>Supportive care (D)</p> Signup and view all the answers

Which of the following is the MOST common clinical presentation of trigeminal neuritis in dogs?

<p>Acute onset of a dropped jaw (A)</p> Signup and view all the answers

Which diagnostic test is MOST useful for confirming denervation of the muscles of mastication in trigeminal neuritis?

<p>Electromyography (EMG) (D)</p> Signup and view all the answers

A dog presents with a dropped jaw, difficulty eating, and muscle atrophy of the temporalis and masseter muscles. Which of the following differentials is LEAST likely?

<p>Otitis media/interna (C)</p> Signup and view all the answers

Which of the following best describes the typical nystagmus associated with peripheral vestibular disease?

<p>Coarse, horizontal or rotatory nystagmus that does not change direction with head position (A)</p> Signup and view all the answers

What is the MOST characteristic finding differentiating peripheral from central vestibular disease regarding proprioceptive deficits?

<p>Peripheral vestibular disease is associated with normal proprioception, while central vestibular disease often presents with ipsilateral proprioceptive deficits (D)</p> Signup and view all the answers

Which of the following clinical signs, if present with facial nerve paralysis, would MOST strongly suggest involvement of the central nervous system rather than idiopathic facial nerve paralysis?

<p>A contralateral hemiparesis (C)</p> Signup and view all the answers

What aspect of the history is MOST important to differentiate geriatric vestibular disease from other causes of vestibular signs?

<p>Peracute onset with improvement within 24-72 hours (A)</p> Signup and view all the answers

In a dog presenting with acute vestibular signs, including head tilt and nystagmus, which historical element would make geriatric vestibular syndrome LESS probable, thus meriting more investigation?

<p>The dog has a history of chronic otitis externa. (A)</p> Signup and view all the answers

What is the MOST appropriate duration of antibiotic therapy for treating otitis media/interna in dogs and cats?

<p>8-12 weeks (A)</p> Signup and view all the answers

If a dog is diagnosed with idiopathic facial paralysis and develops keratitis sicca, what is the MOST important step to include in the treatment plan?

<p>Artificial tears (B)</p> Signup and view all the answers

What condition MUST be ruled out as a possibility for geriatric vestibular syndrome?

<p>Otitis media/interna (A)</p> Signup and view all the answers

A 10-year-old dog presents with acute onset of head tilt, nystagmus, and ataxia. After ruling out otitis media/interna, what diagnostic step is MOST crucial to consider next?

<p>Performing advanced imaging (MRI or CT scan) and potentially a CSF tap (A)</p> Signup and view all the answers

In a patient exhibiting signs of a unilateral peripheral vestibular lesion, you notice the head tilt, nystagmus, and falling to one side. However, you also note the presence of postural reactions and proprioceptive deficits on the opposite side of the body from the lesion. Where is the lesion MOST likely located?

<p>Brainstem (B)</p> Signup and view all the answers

What is the primary function of the trigeminal nerve (CNV)?

<p>Sensory function of the face and motor function of the lower jaw. (B)</p> Signup and view all the answers

In dogs with trigeminal neuropathy, bilateral involvement typically results in which clinical sign?

<p>A dropped jaw. (D)</p> Signup and view all the answers

What is the primary concern regarding water uptake in dogs with a dropped jaw due to trigeminal neuropathy?

<p>Dehydration. (B)</p> Signup and view all the answers

In addition to a dropped jaw, what other clinical sign is seen in approximately 10% of dogs with trigeminal neuropathy?

<p>Horner's syndrome. (B)</p> Signup and view all the answers

Which of the following diagnostic imaging modalities is MOST useful for ruling out nerve sheath tumors in dogs suspected of having trigeminal neuropathy?

<p>Magnetic Resonance Imaging (MRI). (C)</p> Signup and view all the answers

What is the MOST appropriate initial treatment for idiopathic trigeminal neuropathy?

<p>Supportive care. (D)</p> Signup and view all the answers

Which of the following best explains the connection between cranial nerve V and the sympathetic fibers, leading to Horner's syndrome in some dogs with trigeminal neuropathy?

<p>Sympathetic fibers travel along the carotid artery and 'jump' onto cranial nerve V near the ganglion to reach the eye. (A)</p> Signup and view all the answers

Which of the following best describes how to provide hydration to a dog with trigeminal neuropathy and a dropped jaw?

<p>Syringing water directly towards the larynx/pharynx. (D)</p> Signup and view all the answers

When presented with a dog exhibiting a dropped jaw, hypersalivation, and difficulty eating, why is it essential to perform a complete neurological exam?

<p>To rule out involvement of other cranial nerves or neurological structures. (C)</p> Signup and view all the answers

Which clinical sign associated with nerve sheath tumors affecting the trigeminal nerve (CN V) is LEAST common?

<p>Horner's syndrome. (B)</p> Signup and view all the answers

A dog is presented with a dropped jaw, difficulty eating, and muscle atrophy of the temporalis and masseter muscles. Which diagnostic test is MOST useful for confirming denervation of the muscles of mastication?

<p>Electromyography (EMG). (A)</p> Signup and view all the answers

What is the primary goal of supportive care for dogs diagnosed with trigeminal neuropathy?

<p>Maintaining hydration. (A)</p> Signup and view all the answers

When presented with a dog exhibiting a dropped jaw and suspected trigeminal neuropathy, what is the primary reason for performing an MRI?

<p>To rule out a nerve sheath tumor. (B)</p> Signup and view all the answers

A 6-year-old Golden Retriever presents with acute onset of a dropped jaw and difficulty eating. You suspect trigeminal neuropathy. What is the MOST appropriate next step in managing this case?

<p>Perform a thorough neurological exam and consider advanced imaging to rule out other causes. (D)</p> Signup and view all the answers

What is the MOST likely cause of hypersalivation in a dog with trigeminal neuropathy?

<p>Difficulty swallowing due to the dropped jaw. (A)</p> Signup and view all the answers

What aspects of cranial nerve VII function can be affected?

<p>Motor, sensory and autonomic. (C)</p> Signup and view all the answers

The tear production can be suppressed by which cranial nerve?

<ol start="7"> <li>(D)</li> </ol> Signup and view all the answers

What is the most important aspect to consider when managing dogs with facial nerve paralysis to prevent corneal damage?

<p>Regularly lubricating the eye. (B)</p> Signup and view all the answers

What is the significance of an otitis media-interna relating to facial nerve paralysis?

<p>Otitis media-interna is an important differential diagnosis for facial nerve paralysis. (C)</p> Signup and view all the answers

Following a diagnosis of facial nerve paralysis, it's found that there is issues with the salivary glands, what can be inferred?

<p>The innervation of the salivary glands are affected. (C)</p> Signup and view all the answers

Besides supportive care, what treatment can be implemented to help address keratitis due to lack of tear production?

<p>Lubricate, but tarsorrhaphy may be needed. (A)</p> Signup and view all the answers

What is the significance of positional pathological nystagmus?

<p>Nystagmus enhanced by changing position highlights its presence. (C)</p> Signup and view all the answers

Which choice is the LEAST likely option to see when examining a cat?

<p>Ear canal through the eustachian tube. (C)</p> Signup and view all the answers

What are the MAJOR advantage of using MRI to diagnose otitis media/interna compared to a CT scan or radiographs?

<p>MRI can visualize the inner ear structures. (B)</p> Signup and view all the answers

Which cause requires interventional treatment versus just supportive care?

<p>Otitis. (A)</p> Signup and view all the answers

In older dogs with idiopathic vestibular disease, what is the hallmark sign?

<p>Paracute. (D)</p> Signup and view all the answers

If you suspect a geriatric dog is suffering from idiopathic vestibular syndrome, what is an important point to rule out?

<p>Otitis. (D)</p> Signup and view all the answers

What factors help differentiate between central and peripheral vestibular disease?

<p>Normal vs abnormal. (C)</p> Signup and view all the answers

Which cranial nerve is primarily responsible for both sensory innervation of the face and motor control of the muscles of mastication?

<p>Trigeminal nerve (CN V) (C)</p> Signup and view all the answers

A dog presents with a sudden onset of dropped jaw, making it difficult to eat and drink. Bilateral trigeminal neuropathy is suspected. What is the most immediate and critical aspect of supportive care for this patient?

<p>Ensuring adequate hydration through syringe feeding or subcutaneous fluids (D)</p> Signup and view all the answers

In trigeminal neuropathy, the sympathetic fibers destined for the eye 'hitchhike' along which major artery before associating with cranial nerve V?

<p>Carotid artery (C)</p> Signup and view all the answers

Which of the following clinical signs is LEAST likely to be associated with a nerve sheath tumor affecting the trigeminal nerve (CN V)?

<p>Acute onset of bilateral dropped jaw (D)</p> Signup and view all the answers

Idiopathic facial nerve paralysis in dogs is characterized by dysfunction of cranial nerve VII. Which of the following is a common clinical sign?

<p>Loss of menace response and facial symmetry (B)</p> Signup and view all the answers

While idiopathic facial nerve paralysis is often self-limiting, what is a critical aspect of management to prevent potential complications?

<p>Ocular lubrication to prevent corneal damage (B)</p> Signup and view all the answers

In cases of facial nerve paralysis secondary to otitis media/interna, how does the infection most directly lead to nerve dysfunction?

<p>Via inflammatory mediators and direct extension of infection from the middle ear to the facial nerve within the bulla tympanica (A)</p> Signup and view all the answers

A veterinary neurologist suspects vestibular disease in a dog. During the neurological exam, spontaneous nystagmus is not immediately apparent. What technique can be employed to accentuate or trigger nystagmus?

<p>Changing the dog's head position (C)</p> Signup and view all the answers

When differentiating between peripheral and central vestibular disease, which of the following clinical findings is MOST indicative of central vestibular disease?

<p>Vertical nystagmus (A)</p> Signup and view all the answers

Otitis media is most commonly caused by bacteria entering the middle ear via which route?

<p>Extension from otitis externa through the tympanic membrane (B)</p> Signup and view all the answers

Which imaging modality provides the most detailed visualization of the inner ear structures (succulus, utriculus, cochlea) and soft tissues, making it superior for diagnosing otitis interna?

<p>Magnetic Resonance Imaging (MRI) (B)</p> Signup and view all the answers

Ultrasound can be a useful screening tool for otitis media. What finding during an ultrasound examination of the bulla suggests the presence of otitis media?

<p>Visualization of the opposite wall of the bulla due to fluid or tissue content (D)</p> Signup and view all the answers

What is the cornerstone of treatment for idiopathic vestibular syndrome in dogs?

<p>Supportive care (A)</p> Signup and view all the answers

Idiopathic vestibular syndrome is characterized by an acute onset of vestibular signs. Which of the following clinical signs would be UNEXPECTED in uncomplicated idiopathic vestibular syndrome?

<p>Facial nerve paralysis (C)</p> Signup and view all the answers

Which medication is most appropriate for reducing nausea associated with idiopathic vestibular syndrome?

<p>Meclizine (B)</p> Signup and view all the answers

If a 10-year-old dog presents with acute onset vestibular signs (head tilt, nystagmus, ataxia) and a dropped jaw, what is the MOST appropriate next diagnostic step to differentiate between idiopathic vestibular syndrome and more serious conditions?

<p>Perform a thorough neurological exam and consider advanced imaging (MRI/CT) and CSF tap (B)</p> Signup and view all the answers

What is the most likely explanation if a dog recovers from facial nerve paralysis and then develops facial paralysis on the opposite side several months later?

<p>Bilateral idiopathic facial nerve paralysis, which can occur in some cases (C)</p> Signup and view all the answers

Which imaging modality is GENERALLY considered MOST suitable for visualizing the tympanic bulla in dogs and cats suspected of otitis media/interna?

<p>Computed Tomography (CT) (A)</p> Signup and view all the answers

Why are medium to larger breed dogs reportedly more frequently affected by geriatric vestibular syndrome compared to small breeds?

<p>The exact reason is unclear and not well-understood; it is an observed epidemiological trend without a definitive explanation. (D)</p> Signup and view all the answers

In the vast majority of isolated cranial nerve deficits, what is the recommended PRIMARY treatment approach?

<p>Supportive care (A)</p> Signup and view all the answers

Which of the following conditions is an important 'rule-out' when diagnosing geriatric vestibular syndrome?

<p>Otitis media/interna (B)</p> Signup and view all the answers

What is the general prognosis for cranial nerve disorders that are properly diagnosed and treated, according to the provided text?

<p>Variable, depending on the underlying cause, but many idiopathic conditions have a fair to good prognosis with supportive care. (C)</p> Signup and view all the answers

In a dog with trigeminal neuropathy exhibiting a dropped jaw, what is the primary reason for the difficulty in forming a food bolus?

<p>Loss of motor function to the muscles of mastication, preventing closure of the jaw and manipulation of food. (C)</p> Signup and view all the answers

If a dog with trigeminal neuropathy exhibits hypersalivation, what is the MOST likely explanation for this clinical sign?

<p>Inability to effectively swallow saliva due to the dropped jaw and impaired oral motor function. (B)</p> Signup and view all the answers

Why is dehydration a critical concern in dogs with trigeminal neuropathy and a dropped jaw?

<p>The inability to effectively lap and swallow water due to the dropped jaw leads to decreased water intake. (D)</p> Signup and view all the answers

When diagnosing trigeminal neuropathy, what is the primary reason for performing an MRI, even though it is often considered idiopathic?

<p>To rule out compressive lesions such as nerve sheath tumors or other intracranial masses. (B)</p> Signup and view all the answers

What is the general consensus regarding the use of prednisone (a corticosteroid) in treating idiopathic trigeminal neuropathy?

<p>There is no evidence to suggest that prednisone alters the course or outcome of idiopathic trigeminal neuropathy. (B)</p> Signup and view all the answers

In cases of nerve sheath tumors affecting the trigeminal nerve (CN V), why might a dropped jaw NOT always be observed initially?

<p>Tumors typically develop unilaterally, and the unaffected side can compensate for jaw closure. (A)</p> Signup and view all the answers

A cat presents with vestibular signs. During the neurological examination, you do not observe nystagmus initially. What technique can be used to better assess for nystagmus in this cat?

<p>Change the cat's head position. (B)</p> Signup and view all the answers

What is a major advantage of using ultrasound to aid in the diagnosis of otitis media, compared to CT or MRI?

<p>Ultrasound is less expensive and does not require anesthesia. (B)</p> Signup and view all the answers

Which of the following would warrant further diagnostics, such as advanced imaging or a spinal fluid tap, in a dog presenting with acute vestibular signs?

<p>Vertical nystagmus and proprioceptive deficits. (C)</p> Signup and view all the answers

When assessing the bulla with a CT scan for potential otitis media/interna, what is an important aspect to consider for accurate interpretation?

<p>The symmetry and air-filled appearance of both bullae. (C)</p> Signup and view all the answers

Following otic causes, what disease should be considered as a primary differential in a geriatric dog presenting with acute vestibular signs?

<p>Idiopathic vestibular syndrome. (C)</p> Signup and view all the answers

What clinical sign of facial nerve (CN VII) dysfunction would suggest the branch innervating the salivary glands has been affected?

<p>Reduced salivation. (C)</p> Signup and view all the answers

What clinical sign of otitis media/interna may indicate involvement of the facial nerve?

<p>Facial paralysis. (C)</p> Signup and view all the answers

In dogs with trigeminal neuropathy, sympathetic fibers connect to cranial nerve V. Which artery do these sympathetic fibers initially follow before associating with the trigeminal nerve?

<p>Internal carotid artery (C)</p> Signup and view all the answers

When distinguishing between idiopathic trigeminal neuropathy and a nerve sheath tumor affecting cranial nerve V (CNV), which clinical observation would be more indicative of a nerve sheath tumor?

<p>Gradual, progressive muscle atrophy of the muscles of mastication on one side of the face. (B)</p> Signup and view all the answers

What is the rationale behind the recommendation to avoid full neurological exams when assessing cranial nerve disorders?

<p>A dropped jaw shouldn't be the only focus for diagnosing the underlying disease. (D)</p> Signup and view all the answers

In addition to the typical clinical signs, what atypical finding would MOST strongly suggest the presence of a complex case beyond idiopathic trigeminal neuropathy?

<p>Positional vestibular strabismus with vertical nystagmus (A)</p> Signup and view all the answers

Flashcards

Trigeminal Neuropathy

A disorder affecting the trigeminal nerve, often seen in Golden Retrievers and middle-aged to aged dogs.

Signs of Trigeminal Neuropathy

Dropping of the jaw, hypersalivation, and difficulty eating or drinking

Possible causes of Trigeminal Neuropathy

Idiopathic, immune-mediated, paraneoplastic, lymphoma or Neospora canis infection.

Treatment for Trigeminal Neuropathy

Supportive care is indicated, and prednisone does not shorten recovery time.

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Prognosis of Trigeminal Neuropathy

Self-limiting, with recovery within 3 weeks, even without treatment.

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Types of Nerve Sheath Tumors

Can be Neurioma, Neurilemmoma Schwannoma,Malignant schwannoma, Neurofibroma or Neurofibrosarcoma

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Rare signs in Nerve Sheath Tumors

These are rarely observed and often compensated for by the healthy side of the mouth

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Treatments available for Nerve Sheath Tumors

Difficult due to the location but radiation treatment could be useful.

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Etiology of Idiopathic Facial Nerve Paralysis

Etiology- idiopathic and immune mediated disorders are often suspected.

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Histopathology of Idiopathic Facial Nerve Paralysis

This is a progressive paralysis of different nerve fibers.

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Keratitis Sicca

Keratitis sicca - results in dry eye because of a lack of the tear film layer.

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Diagnostics Tests for Idiopathic Facial Nerve Paralysis

CBC, chemistry profile, freeT4, C-TSH, CT scan or MRI, CSF, Eye Exam, Schirmer's Tear Test

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Idiopathic Facial Nerve Paralysis Treatment

Time supportive care, regular eye check, eye drops, treatment of underlying disease.

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Components of Central Vestibular System

4 Vestibular Nuclei, Flocculonodular lobe of cerebellum, Cuadal cerebellar peduncle, Cortex, MFL with connection to CN III,IV, and VI.

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Why is comparison important

It is important to compare input from left and right to determine function

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Clinical signs of Vestibular Disease

Head tilt, vestibular ataxia, ventral strabismus, facial nerve palsy, Horner's syndrome

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Symptoms of Nystagmus

Horizontal, Rotatory, Vertical and Deconjugate eye movement that is spontaneous and pathological.

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Otitis Media-Interna Etiology

Infections often entering via the Tympanic Bulla

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Common Bacteria with Infections

Some common Bacteria Staphylococcus aureus, Proteus, Pseudomonas, E. Coli, or Streptococcus

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How to lavage the Bulla Tympanica

Lavage of the bulla tympanica, Sterile Saline, Chlorhexidine, Tris EDTA or Enrofloxacin Solution

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Etiology of Idiopathic Vestibular Syndrome

Unclear, Viral Labyrinthitis, Hydrops of semicircular ducts in people

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Triggers and Treatments for Idiopathic Vestibular Syndrome

Supportive care, IV fluids, Sedation midazolam, acepromazine, chlorpromazine

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What does the Trigeminal Nerve do?

Sensory function for the face and motor function for the lower jaw.

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What is Trigeminal Neuropathy?

Loss of function of the trigeminal nerve, often with no clear cause.

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What eating problems arise from a dropped jaw?

The dog cannot close its mouth properly, leading to food falling out.

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How is Horner's Syndrome linked to Trigeminal Neuropathy?

Sympathetic fibers 'hitchhike' on cranial nerve V to reach the eye.

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What are rule-outs for Trigeminal Neuropathy?

Nerve sheath tumor, lymphoma, and Neosporosis can cause similar symptoms.

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What Timetable for Improvement from Trigeminal Neuropathy?

Look for improvement in 3 weeks, whether or not medication is used.

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How to maintain hydration for dogs with dropped jaw?

Syringe feeding and/or subcutaneous fluids

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What is the Facial Nerve?

The facial nerve is affected which exits in front of the bulla and has major branches over the face for facial expression.

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Clinical Signs of Facial Nerve Dysfunction?

These typically included ear drop, lip paralysis, drooling and deviation of the nasal septum.

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What is the best way to diagnose a facial nerve deficit?

Often runs with an MRI. That's the most helpful tool

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What can happen to the eye due to facial nerve paralysis?

The tear production is suppressed and can cause corneal ulceration

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Vestibular System

Semicircular ducts sensing rotation; saccules/utricles sensing linear acceleration and gravity.

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Provoking Nystagmus

Change position, lift up the head, or flip the dog upside down to trigger Nystagmus.

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Head tilt

We always see peripheral or central, that makes no difference.

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Differentiating central and peripheral vestibular disease.

The direction of the nystagmus, the speed of the nystagmus, and then especially proprioceptive function, normal versus abnormal

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Otitis Media/Interna Diagnosis

Looking to the bulla, we can do this with X-ray, CT, MRI. We can stick a needle in and collect some fluid.

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Middle Ear

Clear fluid.

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Diagnose Otitis

Looking to the bulla, we can do this with X-ray, CT, MRI. We can stick a needle in and collect some fluid.

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With multiple things are involved

We always remember when multiple things are involved, it's infectious inflammatory lymphoma, trauma, or some kind of a wild degenerative condition.

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Idiopathic Vestibular Disease

Similar names, old dog vestibular syndrome or geriatric vestibular syndrome.

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Clinical sign of Idiopathic Vestibular Syndrome

Paracute onset, vestibular ataxia, unable to stand because they feel so dizzy, nystagmus.

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Nystagmus in Idiopathic Vestibular Syndrome

The dog has a fast resting nystagmus.

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Most common

Peripheral vestibular disease is the most common of all of this.

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Phase One of Eating

An eating process involving grabbing food, closing the mouth, and forming a bolus for swallowing.

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Sympathetic Fiber Pathways

The sympathetic fibers run with the vagal nerve in the lower neck. They then move to the carotid artery, then cranial nerve 5 around the brain.

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Nerve Sheath Tumors (General Definition)

Tumors growing from the nerve, including neurinomas, neurolemnomas, Schwann cell tumors, and neurofibromas.

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Hallmarks of Lower Motor Neuron Disease

Loss of reflexes, muscle tone, and muscle mass due to nerve damage.

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Drooling in Facial Nerve Paralysis

Drooling that occurs because the lips aren't closing properly.

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Facial Nerve Paralysis with Vestibular Signs

A condition where facial nerve paralysis is seen alongside vestibular signs.

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Why Otitis Media Interna Causes Facial Paralysis

Facial nerve runs through dorsal aspect, so an infection can affect the nerve.

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Preventing Corneal Ulcers (Facial Paralysis)

Lubricate the eye, temporary tarsorrhaphy, and regular eye checks.

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Semicircular Ducts, Saccules and Utricles

Ducts sensing rotation; saccules/utricles sensing linear acceleration and gravity.

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Positional Pathological Nystagmus

Changing the patient's head position to better observe nystagmus.

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Disconjugate Nystagmus

This is where both eyes are moving in different directions. This is commonly for a more central pontine disease.

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Ear Canals

The canals run vertically then horizontally so the the infection can travel easily.

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Looking for Otitis

Looking into the ears, look for an otitis externa through visual examination with a video endoscope.

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Bullae on a normal CT

Black because the Bullae are filled with air.

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Seeing Otitis

The huge advantage of MRI, especially to see otitis media and the destructions of the inner ear receptors, is we can see the inner ear organs, succulus, utriculus, cochlea.

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Diagnose Otitis via Ultrasound

Using an ultrasound probe where you can see the ventral part of the bulla produce shadows and the wall because of tissue or fluid conducting.

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Older Dog Syndrome

Idiopathic vestibular syndrome is often related to older dogs.

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Neurological Signs of Idiopathic Vestibular Syndrome

Paracute onset, head tilt, vestibular ataxia, unable to stand because they feel so dizzy, nystagmus, no facial nerve paralysis, no Horner syndrome.

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Rule Out

Idiopathic means isolated signs.

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Why is bilateral damage needed?

If only one side of the jaw is affected then no clinical disease is a seen as the dog is able to compensate

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Nerve positioning?

Facial nerve running withing dorsal aspect of the bulla, any damage in these areas causes nerve deficits.

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If you have a reduced of tear production

Important to lubricate the eye because if you are going to develop a corneal ulcer due to paralysis.

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Vestibular Ataxia

That cat is really leaning to the right side and then walking a little bit, drifting to the right side

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How can we get to an ear infection

External ear canal through the Eustachian tube

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What are some common names?

Quickly some few minutes for what we call idiopathic vestibular syndrome.

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Always do examination

If you're very concerned, you could do an MRI. If you, if the owner is concerned about anesthesia in an older dog, you could give them two or three or four days and watch and see supportive care.

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What is Trigeminal Neuritis?

Also known as idiopathic trigeminal neuropathy, cause is unknown. Likely immune-mediated, affecting the motor branch of CN V.

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Nerve Sheath Tumor CN V: Definition

Neoplasia affecting trigeminal nerve branches; can grow into brainstem causing dysfunction.

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Masticatory Myopathy: Definition

Commonly affects temporal and masseter muscles, more frequent in larger dog breeds.

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Idiopathic Facial Paralysis: Signs

Acute ear drop, lip paralysis, salivation; widened palpebral fissure, potential Keratitis sicca.

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Congenital Deafness: Associations

Associated with pigmentation; merle, piebald genes in dogs; white coat, blue iris in cats.

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What causes deafness?

Results from initial degeneration of the stria vascularis, followed by collapse of the canals

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Vestibular Nerve Disorders: Signs

Signs include head tilt, loss of balance, drifting, and spontaneous nystagmus.

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Peripheral Vestibular Disease: Causes

Includes otitis media/interna, cholesteatoma, fracture, congenital syndrome,Polyneuropathy, geriatric syndrome and nerve sheath tumor

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Central: Causes

Infarction/hemorrhage, GME, necrotizing encephalitis, Rocky Mountain spotted fever, toxoplasmosis, or Fungal disease

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Otitis Interna: Etiology

Extension of inflammation from infection of the external or middle ear.

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Otitis Media/Interna: Bacteria

Staph. aureus, Proteus, Pseudomonas, E. coli, and Streptococcus are common.

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Canine Idiopathic Vestibular Disease: Cause

Vascular disturbance of stria vascularis or hydrops of membranous endolymphatic system.

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Polyneuropathy of Cranial Nerves

Rare condition presenting acute onset of peripheral vestibular signs, head tilt, facial nerve paralysis, ataxia.

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Clinical Signs of Canine IVD

Acute onset peripheral vestibular signs. Head tilt to the same side of the lesion;Fast phase away from the lesion; transient vomiting.

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Feline Idiopathic Vestibular Disease

Idiopathic condition in cats, potentially more common in summer; signs similar to canine version.

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Study Notes

Cranial Nerves

  • There are 12 cranial nerves.
  • Not all cranial nerves are testable, problematic, or disease-causing.
  • The focus will be on selected cranial nerve disorders that cause disease.
  • Cranial nerve disorders are not very common.
  • Disk disease and seizures are the most common neurological conditions.

Trigeminal Nerve Anatomy and Function

  • Trigeminal nerve (CN V) provides sensory function for the face and motor function for the muscles of mastication (lower jaw).
  • Ophthalmic branch: Sensory - ocular area, cornea.
  • Maxillary branch: Sensory – nasal region.
  • Mandibularis branch: Sensory - buccal region and Motor - muscles of mastication.
  • Loss of function often occurs for unclear reasons.
  • A dropped jaw results from disease on both the left and right sides.
  • Dogs with a dropped jaw have difficulty forming a food bolus.
  • Phase one of eating (holding food in the mouth) is problematic.
  • Water uptake is also an issue, and dehydration can set in rapidly.
  • Horner's syndrome can occur due to the sympathetic fibers running with the trigeminal nerve.
  • Sympathetic fibers rely on other structures, like the vagal nerve, carotid artery, and trigeminal nerve.
  • Sympathetic fibers are thin and need to "lean on" other structures for support.
  • Important rule-outs include nerve sheath tumors, lymphoma, and Neospora canis.
  • Hydrating the patient using a syringe, sub-Q fluids, or lifting the food bowl and face with water is a helpful treatment.
  • Example of trigeminal neuropathy
    • A dog has a dropped lower jaw
    • Positive Horner's syndrome
  • Sensory dysfunction can cause pawing or face rubbing.

Disorders of CN V

  • Includes Trigeminal Neuritis and Nerve Sheath Tumor.

Trigeminal Neuritis

  • Golden retrievers are the most affected breed.
  • Middle-aged dogs are commonly affected.
  • Incidence is common.
  • Onset can be acute to peracute.
  • Clinical signs include a dropped jaw, inability to uptake food, and hypersalivation.
  • Approximately 25% of affected dogs display sensory deficits.
  • Horner's syndrome occurs in about 10% of cases.
  • Face sensation is usually normal, but altered trigeminal sensation may be noticed.
  • Very alert, afebrile, responsive animal, lower jaw hangs open, saliva drools from mouth.
  • The definitive cause is unknown.
  • Synonyms include idiopathic trigeminal neuropathy.
  • Histologically a bilateral non-suppurative neuritis in the motor branch of CN V and its ganglion are seen, most likely an immune-mediated disease.
  • Possible etiologies include idiopathic circumstances, immune-mediated issues, paraneoplastic syndrome, lymphoma, and Neospora canis infection.
  • Can swallow when food is placed in the back of the throat.
  • Rapid neurogenic masticatory muscle atrophy, most often bilateral.
  • Can report a unilateral or bilateral Horner's syndrome.
  • Disease is self-limiting, recovery within 14-21 days.
  • Differential diagnosis: Rabies, Polyneuropathy, Masticatory muscle myopathy, Nerve sheath tumors, Abnormal temporomandibular articulation.
  • MRI is an option to rule out tumors.
  • Cerebrospinal fluid (CSF) will show normal cell count and mildly elevated protein concentration.
  • Treatment includes supportive care, such as IV or SC fluids.
  • Prednisone does not shorten recovery time.
  • Steroids have not shown a faster recovery and can increase the requirement for water uptake and can be contra productive.
  • The prognosis shows that this is self-limiting in idiopathic cases with a good prognosis.
  • Recovery is often seen within 3 weeks, with or without prednisone.
  • Work up includes: MRI, CSF, X-ray of mandibular articulation, CT, Elektromyography to prove denervation, Muscle biopsy to rule out masticatory myositis.

Nerve Sheath Tumor of CN V

  • Incidence is rare.
  • A common cause of unilateral trigeminal nerve disease is neoplasia.
  • Can involve several branches of CN V and enter the cavernous sinus.
  • Often grow into the brain stem and produce signs of brainstem dysfunction.
  • There is a large variation in histological subtypes, including Neurioma, Neurilemmoma, Schwannoma, Malignant schwannoma, Neurofibroma, and Neurofibrosarcoma.
  • Signs include chronic and progressive symptoms, older dogs are affected, unilateral temporal muscle, masseter atrophy, and face rubbing.
  • Rarely, Horner's Syndrome is a sign.
  • Jaw weakness is rare due to compensation from the healthy side.
  • May detect weakness in jaw tone, but is often unnoticed due to strength of opposite side.
  • Affects the muscles of mastication (temporal muscle above the zygomatic arch, masseter, and pterygoidius below).
  • Results in lower motor neuron disease, causing loss of reflexes, muscle tone, and muscle mass.
  • A key sign to look for is loss of muscle mass in the face.
  • Differential diagnosis: Trauma, Masticatory myositis, Meningioma compressing nerve roots, Lymphoma.
  • Nerve free tumors are from tumors from the axon, neurinoma or neurolemnoma, a Schwann cell tumor, malignant or benign that's a tumor from the myelin, or then a neurofibroma, neurofibrosarcoma, are nerve tumors.
  • Nerve tumors on cranial nerve number five can grow under the brain and involve multiple structures such as cavernous sinus and optic nerve.
  • Surgical resection is difficult due to the invasion of the brain stem and can be treated with radiation therapy.
  • Diagnosis: History, physical findings, CSF, Electrodiagnostic: electromyography with abnormal findings in muscles innervated by CN V and MRI is the most important test for the diagnosis.
  • Radiation therapy is often the treatment of choice and includes conventional and definitive protocol (20 x 2.5 gray = 50 gray) and stereotactic options for more precision, less side effects, and refined treatments.
  • Limited data is available for survival time with different treatment options.
  • Supportive care has a median survival of 12 days, range of 1 day - 19.2 months, and 40% of animals alive after one year.
  • Surgical resection can lead to survival of 27 months in one dog.
  • Stereotactic radiation therapy with 24 – 30 Gy has a median survival of 14.7 months, a range of 1.5 - 22.7 months, and 60% are alive after one year.
  • Surgical resection is difficult due to deep ventral approach to difficult structures
  • Peripheral nerve tumors are difficult to remove surgically.
  • Usually, tumor has spread along nerve root into brainstem, so radiation therapy is the best treatment option.

Masticatory Myopathy

  • Incidence is common, most often occurs in larger breed dogs and there is no age or gender predilection.
  • Also called eosinophilic myositis or masticatory myositis, but these are thought to be variants or stages of the same disease.
  • Primarily temporal and masseter muscles are affected.
  • Suspected to be immune mediated so autoantibodies have been demonstrated that are directed against proteins of type 2M muscle fibers of masticatory muscles (limb muscles contain type I and 2A fibers).
  • Clinical Signs: Acute onset of swelling of masticatory muscles, usually symmetrical, but may be asymmetrical.
  • Pain on opening the mouth or manipulation can occur.
  • Pseudo trismus: The jaw can be opened only to a certain degree (1 to 1.5 inches).
  • Other signs includes Reluctance to chew, anorexia, weight loss, Exophthalmos may be caused by initial muscle swelling, Blindness or visual deficits are reported because of optic nerve compression or stretching, Fever in some cases and Recurrent episodes with progressive contracture and atrophy of the masticatory muscles, and enophthalmos
  • The acute phase of inflammation may be subclinical so the atrophic and chronic stage of the disease may be recognized more easily.
  • Differential diagnosis: Polymyositis, Infectious myopathy, Trigeminal neuropathy, Temporomandibular joint disease, Retrobulbar abscessation.
  • The masticatory muscles are antigenically different from other skeletal muscles, because they are derived embryological from the mesoderm of the first branchial arches and are innervated by a cranial nerve.
  • Diagnosis: CBC: eosinophilia may be present, Serum chemistry: muscle enzymes normal or slightly elevated, EMG: spontaneous activity with positive sharp waves, complex repetitive discharge or muscle biopsy.
  • Muscle biopsy: loss of muscle fibers, necrosis, muscle fiber atrophy, lymphoplasmacytic infiltrates, and less frequently eosinophils, connective tissue and fibrosis may be present
  • Radiographs of temporomandibular joint, ANA, Antibodies against 2M fiber proteins, In some dogs an MRI can diagnostically be very helpful.
  • Treatment: Corticosteroids: prednisolone 1-2 mg/kg PO, SID, for 3-4 weeks, then taper the dose watching for recurrence of signs
  • Immunomodulator: azathioprine 2 mg/kg SID, mycophenolate 10 mg/kg BID, cyclosporine.
  • Patient must be Monitored to therapy by the ability to open the jaw with Serial evaluation of muscle enzymes.
  • Relapses are common and complete withdrawal of medication may be not possible with a Prognosis favorable if the disease is treated early.

Facial Nerve Anatomy and Function

  • Facial nerve (CN VII) motor function affects facial expression, palpebral reflex, and ear movement.
  • Innervates muscles of facial expression.
  • Sensory - rostral two thirds of the tongue, ear drum, meatus accusticus
  • Also innervates salivary glands and can affect tear production
  • Sensory function includes innervating the inner ear and sensing pain.
  • Parasympathetic – fibers to lacrimal gland and salivary glands (sublingual and mandibular).

Idiopathic Facial Nerve Paralysis

  • Etiology is idiopathic, but specific causes are unclear.
  • In some cases, an immune-mediated disorder is suspected.
  • Cocker Spaniels and Beagles get affected.
  • This occurs in middle-aged dogs, around 3-6 years of age.
  • Incidence is common.
  • Histopathology signs include axonal degeneration, and large diameter fibers frequently are more affected.
  • Clinical signs include ear drop, lip paralysis, salivation, difficulty in food uptake, and Deviation of nasal septum.
  • Can also see Acute onset of ear drop, lip paralysis, and salivation.
  • Absent palpebral reflex is possible and the palpebral fissure is usually widened and fails to close.
  • Absent menace reflex due to facial paresis/ paralysis
  • Keratitis sicca in about 20% of patients.
  • Clinical signs with vestibular signs include a Unilateral facial nerve paralysis, Head tilt, Vestibular ataxia, and Pathological nystagmus.
  • Usually unilateral but may be bilateral, or onset at the other side later
  • Differentials include otitis media/interna, trauma, fractures, hypothyroidism, and neoplasia.
  • Helpful diagnostic tests include CBC, chemistry profile, freeT4, C-TSH, CT scan or MRI, CSF, and eye exam.
  • Work up includes: Neurological exam to rule out other causes and find no otitis or other CN signs.
  • Treatments involve time and supportive care, regular eye checks to rule out ulceration and check tear production, and eye drops.
  • It can be treated by underlying disease.
  • Therapy Depending of the cause, so use artificial tears if keratitis sicca is present.
  • The prognosis shows recovery within 2-3 months.
  • The other side can be affected 2-4 months later in about 50% of the cases.
  • Key signs include ear drop, lip paralysis, drooling, deviation of the nasal septum, loss of palpebral reflex, and loss of menace reflex.
  • Dry eye (keratitis sicca) can occur in about 20% of cases.
  • Facial nerve paralysis can be combined with vestibular signs, which may be idiopathic.
  • An otitis media interna is another differential diagnosis.
  • Improvement takes about two to three months and is often not 100% complete.
  • The opposite side can be affected later (2-4 months).
  • Lubricating the eye is important due to the risk of corneal ulcers.
  • A temporary tarsorrhaphy can be considered to prevent ulceration.
  • Other Differential diagnosis: Otitis media/ interna, Trauma to external styloid foramen, Petrosal bone fractures, Polyradiculoneuritis, Laryngeal paralysis-polyneuropathy complex, Insulinoma, Hypothyroidism, Myasthenia gravis, Brain stem: inflammation or neoplasia and Pituitary neoplasia.
  • Facial contracture (small palpebral fissure, lip retraction, deviation of lip and nose toward affected side) can be a squeal.

Vestibulocochlear Nerve Anatomy and Function

  • Vestibulocochlear nerve (CN VIII): Sensory - Hearing and Balance
  • The peripheral system of the vestibular system has semicircular ducts, sacculus, utriculus and vestibulocochlear nerve.
  • The Auditory Portion: Dysfunction results in Impaired hearing or deafness while the Vestibular Portion: its dysfunction results in Vestibular syndromee.
  • Produces a continuous discharge of 100Hz at rest.
  • Two types of central vestibular system: 4 vestibular nuclei, Flocculonodular lobe of cerebellum, Caudal cerebellar peduncle, Cortex, MFL with connection to CN III, IV, and VI, and Vestibulo-spinal tracts.
  • Input from the left versus the right drives vestibular function comparison.
  • Clinical Signs of Vestibular Disease include Head tilt, Vestibular ataxia with Drifting or falling, Ventralstrabismus, Facial nerve palsy, and Horner's syndrome.
  • Types of nystagmus Spontaneous are horizontal, Rotatory, deconjugate, and vertical.
  • Positional Nystagmus are horizontal, Rotatory, deconjugate, and vertical.
  • Semicircular ducts sense rotation.
  • Sacculus and utriculus sense linear acceleration and gravity.
  • Vestibular system has a complex connection to the eyes and the rest of the brain.
  • Otitis media interna can cause facial nerve paralysis and Horner's syndrome.
  • Nystagmus can be horizontal, and disconjugate nystagmus indicates central disease.
  • Change position (lifting or flipping) can trigger nystagmus and make it more visible (positional pathological nystagmus).

Cochlear nerve disorders – CN VIII(Classification and etiology of deafness)

  • Inherited congenital sensorineural=Associated with pigmentation with malformation.
  • Acquired later onset sensorineural=Otitis media/interna, presbycusis and ototoxicity.
  • Acquired later onset conductive=Otits media/ interna with Sclerosis of the ossicles.
  • Deafness results from initial degeneration of the stria vascularis followed by collapse of the canals (Reissnersche membrane, cochlear duct) and the sensineural receptors (organ of Corti).
  • Secondarily, there is retrograde degeneration of the spiral ganglion, cochlear nerve (cochlear division), central auditory pathways and auditory cortex.
  • Deafness develops within the first weeks of life and Dalmatians are not deaf until 3-6 weeks after birth.
  • Frequently found in association with pigmentation pattern, where increasing amounts of white in the hair coat increases the likelihood of deafness.

Cats:

  • The combination of with white coat color and blue iris color increases the risk of deafness, inherited in an autosomal dominant manner.

Dogs:

  • Deafness is associated with merle gene, piebald or extreme piebald gene.
  • Several breeds are affected, especially in those with merlin trait (collies, border collies, English setters, Australian heelers, old English sheepdogs, great Danes, dachshunds, bull terriers etc.)
  • Deafness may also occur sporadically in other dogs, some of which have a white coat color without the merle trait.
  • The Dalmatian is the number one breed affected with congenital deafness.
  • Deafness is clearly linked to the extreme piebald gene and blue eyed Dalmatians are more likely to be deaf than Dalmatians with brown eyes.

Diagnosis

  • Observation of behavior to sounds that are a part of it's natural environment but is difficult to assess in animals with partial bilateral or complete unilateral involvement.
  • Behavioral evaluation: observe the animal's behavioral response to sounds that are a part of its natural environment. This is difficult to assess in animals with partial bilateral or complete unilateral involvement.
  • BAER is an excellent method for detecting unilateral problems.

Vestibular Disease Comparison

  • Peripheral: the head tilt is yes, the Vestibular ataxia is yes, the Patho. Nystagmus is horizontal rotatory, the beats per minute is fast, the Positional nystagmus is yes.
    • With VII, VIII possible CN deficits, possible Horner's syndrome, and normal proprioception.
  • Central: the head tilt is yes, the Vestibular ataxia is yes, the Patho. Nystagmus is vertical, the beats per minute is slow, the Positional nystagmus is yes.
    • There can be CN deficits that are multiple, rare Horner's syndrome, and abnormal Proprioception.

Otitis Media-Interna

  • Etiology: The infection of bulla tympanica comes from Ear canal, Tuba eustachii, and Hematogenous pathways.
  • Bacteria include Staphylococcus aureus, Proteus, Pseudomonas, E. Coli, Streptococcus, Enterobacter, and Malassezia sp.
  • Clinical signs are often fast and progressive, head tilt, vestibular ataxia and spontaneous nystagmus
  • Facial nerve paralysis is frequent in 2/3 cases.
  • Horner's syndrome occurs in about 10% of the cases.
  • Diagnosis involves Otoscopy, Bulla series, CT, MRI, and Myringotomy.
    • With Myringotomy, there is Cytological analysis and Culture and sensitivity.
  • Ultrasound has two characteristics: Normal: Hypoechoic and Otitis Media: Far wall becomes visible.
  • Treatment involves the knowledge of infectious etiology and antibiogram to be very helpful, medical courses of action, long-term antibiotics for bactericidal purposes like Baytril.
    • Amoxicillin + clavulanic acid are needed, Cephalosporine, Clindamycin, Erythomycin and bulla tympanica lavage with sterile saline.
    • An alternative course of action is a 1% betadine solution, Chlorhexidine, Tris EDTA or a 2.27% enrofloxacin solution.
  • Surgical options include ear ablation, bulla osteoectomy and exploration of the brainstem.
  • Medical management needs long-term treatment for over 2 months, and antibiotics selected based on culture and testing of susceptibility.
  • Infection of bulla tympanica comes from the ear canal, tuba eustachii and hematogenous pathways.
  • In dogs always do an otitis externa check because ear canal is first vertical, then horizontal, then we have the tympanic membrane and then we have the middle ear.
  • Key diagnostic measures include otoscopy, bulla series, CT, MRI, and myringotomy.
  • Cytological analysis and culture and sensitivity should be performed with myringotomy.
  • With ultrasound the Normal read is hypoechoic, and otitis media: Far wall becomes visible.
  • The ear canal is for first vertical, then horizontal, then the tympanic membrane, and then the middle ear.
  • The Eustachian tube going to the larynx pharynx is important for horses.
  • A CT scan is an excellent tool for looking for otitis media in cats due to their thin bullae.
  • An MRI can visualize the inner ear organs (sacculus, utriculus, cochlea) and diagnose otitis media and interna.
  • Long term (8-12 weeks) systemic antibiotics chosen based on bacterial culture and sensitivity when available.
  • Careful use of topic disinfectants and Bulla osteotomy for surgical drainage/debridement. Inflammatory polyps must be surgically removed
  • Signs are consistent with a unilateral peripheral vestibular lesion, Ipsilateral facial palsy, Horner's syndrome, and keratitis sicca may be observed.
  • Unilateral deafness may occur, but is difficult to detect clinically.
  • Diagnosis includes history of recurrent or chronic otitis externa/media with Otoscopic exam where you may often see a diseased or even ruptured tympanic membrane.
  • Other testing includes MRI or CT scan to assess extension and severity of infection in some dogs and cats.
  • Differential diagnosis includes idiopathic vestibular disease, Trauma, Neoplasia, Neuropathy/ polyneuropathy
  • Good to guarded if osteitis of petrous temporal bone is present.

Canine Idiopathic Vestibular Syndrome

  • Similar names include Old dog vestibular syndrome and Geriatric vestibular syndrome.
  • Signalment shows any breed of dogs over 10 years of age, and medium to large breeds mostly get affected typically over 12.5 to 13 years of age.
  • Etiology is Vague, but involves viral labyrinthitis and hydrops of semicircular ducts in people.
  • A vascular disturbance of the stria vascularis with an altered concentration of potassium in the endolymph and a similar syndrome is caused by hydrops and rupture of the membranous endolymphatic system, most often in the semicircular ducts.
  • Clinical signs are: peracute to acute onset, head tilt, vestibular ataxia, often unable to stand but salivation, fast spontaneous, rotatory nystagmus
  • No facial nerve paralysis or Horner's syndrome.
  • Clinical signs include: peracute to acute onset of peripheral vestibular disease with a head tilt to the same side of the lesion, rolling, falling to the same side of the lesion, spontaneous horizontal/rotary nystagmus with fast phase away from the lesion and transient vomiting.
  • The nystagmus usually lasts 24-72 hours and once It has disappeared it can often be elicited again by quickly turning the animal over on its back (positional nystagmus).
  • By the 8th to 10th day, walking and the head tilt are markedly improved, but may persist for several weeks or indefinitely.
  • Its important to rule out other important differentials like otitis media/interna, stroke, trauma, and neoplasia.
  • Work up: Rule out other causes: no other cranial nerve deficits, expect spontaneous nystagmus, the Otoscopic exam is normal, Bulla series are normal, CSF is normal and has a Non progressive course.
  • Treatment includes supportive care, IV fluids, and light Sedation: midazolam, acepromazine, and chlorpromazine.
  • Therapy is Supportive care and most important
  • The prognosis shows Improvement within 24-72 hours, Recovery up to 2 weeks, and possible relapses.
  • Recovery is due to compensation.
  • Also known as old dog vestibular syndrome or geriatric vestibular syndrome.
  • The reason this gets the name Geriatric Vestibular Syndrome because the dogs are often more than 10 years of age.
  • Dogs with a vague etiology is viral labyrinthitis and hydrops of semicircular ducts in people.
  • Medium to large breed dogs are more often presented to get this.
  • Key clinical signs include peracute to acute onset, head tilt, vestibular ataxia, inability to stand, and nystagmus.
  • Facial nerve paralysis or Horner's syndrome are not involved.
  • Improvement is typically seen within 24-72 hours, but full recovery takes up to two weeks.

Disorders of CN X

  • Dysphagia can be a sign of Vagus nerve dysfunction.

Polyneuropathy of cranial nerves

  • Incidence: Rare condition, not well described and reported and the etiology is unknown, but possibly immune mediated.
  • Diagnosis: MRI is an important test to rule out intracranial lesions and CSF analysis shows of a normal WBC and a slightly elevated protein level for Work up.
  • Clinical signs are acute onset of peripheral vestibular signs with horizontal to rotator nystagmus, head tilt, facial nerve paralysis, vestibular ataxia
  • Treatment: Supportive care

Feline idiopathic vestibular disease

  • Clinical signs, course of disease, diagnostic tests, therapy and prognosis are similar to the canine disorder
  • Has an increased incidence in the summer and occurs in adult cats of all ages.
  • A viral infection is suspected, but not proven and residual neurological signs may be permanent.

Conclusions

  • Single isolated CN disorders are rare.
  • Peripheral vestibular disease is the most common.
  • Including Otitis media/externa or idiopathic vestibular syndrome.
  • Good knowledge of anatomy is important and expectations of what deficits a certain cranial nerve dysfunction should produce can greatly help.
  • If diagnosed and treated appropriately, decent outcomes can be achieved in many cases.
  • Single isolated coronary nerve deficits or disorders are relatively rare.
  • Peripheral vestibular disease is the most common of all of this includes otitis cases as well or idiopathic vestibular syndrome cases
  • The big treatment differences is with otitis, here we are more interventional with medical intervention and treatment.

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