Tricarboxylic Acid Cycle (TCA Cycle) - Prof S Nayak

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Questions and Answers

What is the final common oxidative pathway for carbohydrates, fats, and amino acids?

  • Glycolysis
  • Electron transport chain
  • Tricarboxylic acid cycle (correct)
  • Fatty acid oxidation

What is the product of the oxidation of acetyl CoA in the TCA cycle?

  • ATP + NADH
  • CO2 + ATP
  • NADH + FADH2
  • CO2 + H2O (correct)

What is the site of the TCA cycle?

  • Mitochondrial outer membrane
  • Mitochondrial matrix (correct)
  • Cytosol
  • Mitochondrial inner membrane

What is the intermediate formed immediately after the addition of H2O to cis-aconitate?

<p>Isocitrate (A)</p> Signup and view all the answers

What is the next intermediate formed after isocitrate in the TCA cycle?

<p>Oxalosuccinate (D)</p> Signup and view all the answers

What is the net gain of ATP from the complete oxidation of glucose?

<p>38 ATP (B)</p> Signup and view all the answers

What is the role of anaplerotic reactions in the citric acid cycle?

<p>To replenish the intermediates of the citric acid cycle (D)</p> Signup and view all the answers

What is the byproduct of the spontaneous decarboxylation of oxalosuccinate?

<p>α-Ketoglutarate (A)</p> Signup and view all the answers

What is the amphibolic nature of the citric acid cycle?

<p>It is both catabolic and anabolic, producing ATP and NADH, while also synthesizing glucose and amino acids (A)</p> Signup and view all the answers

What is the effect of fluoroacetate on the citric acid cycle?

<p>It inhibits aconitase (B)</p> Signup and view all the answers

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