10 Questions
What is the final common oxidative pathway for carbohydrates, fats, and amino acids?
Tricarboxylic acid cycle
What is the product of the oxidation of acetyl CoA in the TCA cycle?
CO2 + H2O
What is the site of the TCA cycle?
Mitochondrial matrix
What is the intermediate formed immediately after the addition of H2O to cis-aconitate?
Isocitrate
What is the next intermediate formed after isocitrate in the TCA cycle?
Oxalosuccinate
What is the net gain of ATP from the complete oxidation of glucose?
38 ATP
What is the role of anaplerotic reactions in the citric acid cycle?
To replenish the intermediates of the citric acid cycle
What is the byproduct of the spontaneous decarboxylation of oxalosuccinate?
α-Ketoglutarate
What is the amphibolic nature of the citric acid cycle?
It is both catabolic and anabolic, producing ATP and NADH, while also synthesizing glucose and amino acids
What is the effect of fluoroacetate on the citric acid cycle?
It inhibits aconitase
Test your understanding of the TCA cycle, also known as the Kreb's cycle or Citric acid cycle, including its role in energy production and intermediate synthesis. Calculate the energy yield per turn of the cycle and describe the further processing of acetyl-CoA.
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