Tricarboxylic Acid Cycle (TCA Cycle) - Prof S Nayak
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Questions and Answers

What is the final common oxidative pathway for carbohydrates, fats, and amino acids?

  • Glycolysis
  • Electron transport chain
  • Tricarboxylic acid cycle (correct)
  • Fatty acid oxidation

    • What is the product of the oxidation of acetyl CoA in the TCA cycle?

  • ATP + NADH
  • CO2 + ATP
  • NADH + FADH2
  • CO2 + H2O (correct)

    • What is the site of the TCA cycle?

  • Mitochondrial outer membrane
  • Mitochondrial matrix (correct)
  • Cytosol
  • Mitochondrial inner membrane

    • What is the intermediate formed immediately after the addition of H2O to cis-aconitate?

    <p>Isocitrate</p> Signup and view all the answers

    What is the next intermediate formed after isocitrate in the TCA cycle?

    <p>Oxalosuccinate</p> Signup and view all the answers

    What is the net gain of ATP from the complete oxidation of glucose?

    <p>38 ATP</p> Signup and view all the answers

    What is the role of anaplerotic reactions in the citric acid cycle?

    <p>To replenish the intermediates of the citric acid cycle</p> Signup and view all the answers

    What is the byproduct of the spontaneous decarboxylation of oxalosuccinate?

    <p>α-Ketoglutarate</p> Signup and view all the answers

    What is the amphibolic nature of the citric acid cycle?

    <p>It is both catabolic and anabolic, producing ATP and NADH, while also synthesizing glucose and amino acids</p> Signup and view all the answers

    What is the effect of fluoroacetate on the citric acid cycle?

    <p>It inhibits aconitase</p> Signup and view all the answers

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