Treponema Palladium - Pallidum Observatory Quiz
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Questions and Answers

What is the primary method used to directly visualize the Treponema Pallidum organism?

  • Dark field microscopy (correct)
  • Rapid plasmin reagent (RPR) test
  • Video display
  • FTA Antibody Test (FTA-ABS)

    • Which of the following is a characteristic of the primary stage of syphilis infection?

  • Condoloma lata with flat-topped bumps
  • Systemic disease with a maculopapular rash
  • Painless genital chancre (correct)
  • Formation of gummas

    • Which screening test for syphilis is known to have a high incidence of false positives due to cross-reactivity with other antigens?

  • Rapid plasmin reagent (RPR) (correct)
  • Dark field microscopy
  • FTA Antibody Test (FTA-ABS)
  • Video display - Venereal Disease Research Laboratory (VDRL)

    • What is the purpose of the FTA Antibody Test (FTA-ABS) in the diagnosis of syphilis?

    <p>Confirmation of a positive screening test</p> Signup and view all the answers

    Which of the following is a characteristic of the secondary stage of syphilis infection?

    <p>Systemic disease with a maculopapular rash</p> Signup and view all the answers

    What is the primary mode of transmission for Treponema Pallidum, the causative agent of syphilis?

    <p>Sexually transmitted disease</p> Signup and view all the answers

    What is the cause of the aortic pathologic aneurysm mentioned in the text?

    <p>Destruction of the vasovasorum</p> Signup and view all the answers

    What is the significance of the 'columns in the back that are cracked and damaged' mentioned in the text?

    <p>It refers to demyelination of nerves and posterior column of the spinal cord</p> Signup and view all the answers

    What is the significance of the 'greeter wearing argyle sweater with kid shining light into the eyes' mentioned in the text?

    <p>It refers to a type of pupillary abnormality</p> Signup and view all the answers

    Which of the following is NOT a congenital symptom of syphilis mentioned in the text?

    <p>Cleft palate</p> Signup and view all the answers

    What is the recommended treatment for syphilis mentioned in the text?

    <p>Penicillin G</p> Signup and view all the answers

    What is the 'sign directing students' referring to in the text?

    <p>It refers to the Jarisch-Herxheimer reaction</p> Signup and view all the answers

    What type of organism is Treponema Pallidum, the causative agent of syphilis?

    <p>Spirochete</p> Signup and view all the answers

    Which of the following is a characteristic of the primary stage of syphilis infection?

    <p>Painless genital chancre</p> Signup and view all the answers

    What is the main purpose of the FTA Antibody Test (FTA-ABS) in the diagnosis of syphilis?

    <p>To confirm a positive screening test for syphilis</p> Signup and view all the answers

    Which screening test for syphilis is known to have a high incidence of false positives due to cross-reactivity with other antigens?

    <p>VDRL</p> Signup and view all the answers

    What is the primary mode of transmission for Treponema Pallidum, the causative agent of syphilis?

    <p>Sexually transmitted</p> Signup and view all the answers

    What is the primary method used to directly visualize the Treponema Pallidum organism?

    <p>Dark field microscopy</p> Signup and view all the answers

    What is the mechanism by which syphilis causes an aortic pathologic aneurysm?

    <p>Destruction of the vasa vasorum, leading to ischemia and weakening of the aortic wall</p> Signup and view all the answers

    What is the likely cause of the 'constellations' mentioned in the text?

    <p>Skin hyperpigmentation associated with congenital syphilis</p> Signup and view all the answers

    Which of the following is NOT a congenital symptom of syphilis mentioned in the text?

    <p>Microcephaly</p> Signup and view all the answers

    What is the likely cause of the 'tree barking' mentioned in the text?

    <p>Gummatous lesions associated with tertiary syphilis</p> Signup and view all the answers

    What is the likely cause of the 'Argyle Robertson pupil' mentioned in the text?

    <p>Damage to the oculomotor nerve caused by tertiary syphilis</p> Signup and view all the answers

    What is the likely cause of the 'Jarisch-Herxheimer reaction' mentioned in the text?

    <p>Release of endotoxins from dying Treponema pallidum</p> Signup and view all the answers

    Study Notes

    Syphilis Diagnosis & Treatment

    • Dark-field microscopy is the primary method for directly visualizing Treponema Pallidum.
    • Chancre is a painless ulcer, a characteristic of the primary stage of syphilis.
    • VDRL (Venereal Disease Research Laboratory) test has a high incidence of false positives due to cross-reactivity.
    • FTA Antibody Test (FTA-ABS) confirms the presence of specific antibodies against Treponema Pallidum, aiding in syphilis diagnosis.
    • Skin rash is a characteristic of the secondary stage of syphilis.
    • Sexual contact is the primary mode of transmission for Treponema Pallidum.
    • Aortic aneurysm is caused by inflammation and weakening of the aorta due to syphilis infection.

    Syphilis Pathology & Symptoms

    • Columns in the back that are cracked and damaged likely refer to tabes dorsalis, a neurological complication of late syphilis. It's a result of damage to the spinal cord.
    • Greeter wearing argyle sweater with kid shining light into the eyes likely refers to the Argyll Robertson pupil, a neurological symptom of neurosyphilis, where the pupils react to accommodation but not to light.
    • Congenital deafness is NOT a congenital symptom of syphilis, while saddle nose deformity is a common symptom.
    • Penicillin is the recommended treatment for syphilis.
    • Sign directing students likely refers to a classic symptom of Hutchinson's teeth, a congenital defect caused by syphilis.

    Syphilis Overview & Transmission

    • Treponema Pallidum is a spirochete, a type of bacteria.
    • Chancre is a painless ulcer, a characteristic of the primary stage of syphilis infection.
    • FTA Antibody Test (FTA-ABS) confirms the presence of specific antibodies against Treponema Pallidum, aiding in syphilis diagnosis.
    • VDRL (Venereal Disease Research Laboratory) test has a high incidence of false positives due to cross-reactivity.
    • Sexual contact is the primary mode of transmission for Treponema Pallidum.
    • Dark-field microscopy is the primary method for directly visualizing Treponema Pallidum.
    • Syphilis causes an aortic aneurysm by inflammatory damage and weakening of the aorta due to the bacteria.

    Syphilis Symptoms & Complications

    • Constellations likely refer to a neurological symptom of neurosyphilis, where a patient can feel pain, tingling, or numbness in their skin, potentially appearing in constellations.
    • Congenital deafness is NOT a congenital symptom of syphilis, while saddle nose deformity is a common symptom.
    • Tree barking likely refers to the syphilitic gumma, late-stage lesions often appearing on the skin and bones.
    • Argyll Robertson pupil is likely caused by syphilis infection, where pupils don't react to light but do react to accommodation.
    • Jarisch-Herxheimer reaction is a common complication of penicillin treatment for syphilis, causing a sudden, temporary worsening of the initial symptoms.

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    Description

    Test your knowledge on Treponema Palladium, a spiral-shaped spirochete organism that can only be grown in rabbit testes. Learn about its transmission as a sexually transmitted disease and the use of dark field microscopy for visualization. Explore screening tests like VDRL and RPR for detection.

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