Treatment of Peptic Ulcer

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Questions and Answers

What is the main cause of duodenal ulcer?

  • Excessive alcohol consumption
  • Intake of NSAIDs
  • Chronic Helicobacter pylori infection (correct)
  • Smoking

Which defensive factor plays a role in preventing the formation of peptic ulcer?

  • H. pylori infection
  • Mucus layer (correct)
  • Corticosteroids
  • Alcohol consumption

What is the most common symptom of peptic ulcer?

  • Gastrointestinal tract bleeding (hematemesis and/or melena)
  • Loss of appetite and weight loss
  • Nausea and vomiting
  • Epigastric pain and discomfort (correct)

Which lifestyle measure can help in the management of peptic ulcer?

<p>Avoiding smoking and alcohol consumption (D)</p> Signup and view all the answers

What is the focal defect that forms on the inside lining of the lower esophagus, stomach, or duodenum in the case of peptic ulcer?

<p>Focal erosion extending from mucosa to submucosa and even deeper to the muscular layer (B)</p> Signup and view all the answers

Which drug acts by causing irreversible inhibition of the H+/ K+ ATPase, thereby reducing both basal and stimulated acid secretion?

<p>Omeprazole (A)</p> Signup and view all the answers

Which proton pump inhibitor (PPI) has a rapid onset and long duration of action, and is destroyed by gastric acidity?

<p>Pantoprazole (D)</p> Signup and view all the answers

Which H2 receptor antagonist has the most potent pharmacological action and is excreted mainly by the kidney, making it preferred in liver dysfunction?

<p>Famotidine (D)</p> Signup and view all the answers

Which H2 receptor antagonist acts as an inhibitor of cytochrome p450 and can cause reversible gynecomastia and sexual dysfunction in males?

<p>Cimetidine (A)</p> Signup and view all the answers

Which lifestyle measure is recommended for the management of peptic ulcer to reduce acid secretion?

<p>Reducing stress (C)</p> Signup and view all the answers

Which antibiotics possess a Beta-lactam ring?

<p>Cephalosporins (C)</p> Signup and view all the answers

Which class of antibiotics acts by inhibiting bacterial cell wall synthesis?

<p>Glycopeptide antibiotics (B)</p> Signup and view all the answers

Which antibiotics are classified as Inhibitors of protein synthesis?

<p>Tetracyclines (C)</p> Signup and view all the answers

Which antibiotics are considered beta-lactamase inhibitors?

<p>Carbapenems (D)</p> Signup and view all the answers

Which antibiotics affect cell membrane permeability?

<p>Aminoglycosides (C)</p> Signup and view all the answers

Which antibiotics belong to the class of drugs affecting metabolic pathways?

<p>Sulfonamides (B)</p> Signup and view all the answers

Which enzyme is secreted by some bacteria and leads to inactivation of beta-lactam antibiotics, causing resistance?

<p>Penicillinase (B)</p> Signup and view all the answers

Which type of penicillin is considered narrow-spectrum?

<p>Nafcillin (B)</p> Signup and view all the answers

What is the mechanism of action of penicillins?

<p>Inhibit cell wall synthesis (A)</p> Signup and view all the answers

Which penicillin is eliminated through both renal and biliary excretion?

<p>Oxacillin (B)</p> Signup and view all the answers

In which type of infections are streptococcal infections commonly treated with penicillins?

<p>Respiratory infections (B)</p> Signup and view all the answers

What is a common adverse effect associated with penicillins?

<p>Hypersensitivity reactions (A)</p> Signup and view all the answers

Which of the following is NOT classified as an inhibitor of bacterial cell wall synthesis?

<p>Fosfomycin (A)</p> Signup and view all the answers

Which antibiotic is considered a glycopeptide antibiotic?

<p>Vancomycin (C)</p> Signup and view all the answers

What is the classification of cephadroxil, cephalexin, and cefazolin?

<p>1st generation cephalosporins (B)</p> Signup and view all the answers

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