Treatment of Peptic Ulcer
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Questions and Answers

What is the main cause of duodenal ulcer?

  • Excessive alcohol consumption
  • Intake of NSAIDs
  • Chronic Helicobacter pylori infection (correct)
  • Smoking
  • Which defensive factor plays a role in preventing the formation of peptic ulcer?

  • H. pylori infection
  • Mucus layer (correct)
  • Corticosteroids
  • Alcohol consumption
  • What is the most common symptom of peptic ulcer?

  • Gastrointestinal tract bleeding (hematemesis and/or melena)
  • Loss of appetite and weight loss
  • Nausea and vomiting
  • Epigastric pain and discomfort (correct)
  • Which lifestyle measure can help in the management of peptic ulcer?

    <p>Avoiding smoking and alcohol consumption</p> Signup and view all the answers

    What is the focal defect that forms on the inside lining of the lower esophagus, stomach, or duodenum in the case of peptic ulcer?

    <p>Focal erosion extending from mucosa to submucosa and even deeper to the muscular layer</p> Signup and view all the answers

    Which drug acts by causing irreversible inhibition of the H+/ K+ ATPase, thereby reducing both basal and stimulated acid secretion?

    <p>Omeprazole</p> Signup and view all the answers

    Which proton pump inhibitor (PPI) has a rapid onset and long duration of action, and is destroyed by gastric acidity?

    <p>Pantoprazole</p> Signup and view all the answers

    Which H2 receptor antagonist has the most potent pharmacological action and is excreted mainly by the kidney, making it preferred in liver dysfunction?

    <p>Famotidine</p> Signup and view all the answers

    Which H2 receptor antagonist acts as an inhibitor of cytochrome p450 and can cause reversible gynecomastia and sexual dysfunction in males?

    <p>Cimetidine</p> Signup and view all the answers

    Which lifestyle measure is recommended for the management of peptic ulcer to reduce acid secretion?

    <p>Reducing stress</p> Signup and view all the answers

    Which antibiotics possess a Beta-lactam ring?

    <p>Cephalosporins</p> Signup and view all the answers

    Which class of antibiotics acts by inhibiting bacterial cell wall synthesis?

    <p>Glycopeptide antibiotics</p> Signup and view all the answers

    Which antibiotics are classified as Inhibitors of protein synthesis?

    <p>Tetracyclines</p> Signup and view all the answers

    Which antibiotics are considered beta-lactamase inhibitors?

    <p>Carbapenems</p> Signup and view all the answers

    Which antibiotics affect cell membrane permeability?

    <p>Aminoglycosides</p> Signup and view all the answers

    Which antibiotics belong to the class of drugs affecting metabolic pathways?

    <p>Sulfonamides</p> Signup and view all the answers

    Which enzyme is secreted by some bacteria and leads to inactivation of beta-lactam antibiotics, causing resistance?

    <p>Penicillinase</p> Signup and view all the answers

    Which type of penicillin is considered narrow-spectrum?

    <p>Nafcillin</p> Signup and view all the answers

    What is the mechanism of action of penicillins?

    <p>Inhibit cell wall synthesis</p> Signup and view all the answers

    Which penicillin is eliminated through both renal and biliary excretion?

    <p>Oxacillin</p> Signup and view all the answers

    In which type of infections are streptococcal infections commonly treated with penicillins?

    <p>Respiratory infections</p> Signup and view all the answers

    What is a common adverse effect associated with penicillins?

    <p>Hypersensitivity reactions</p> Signup and view all the answers

    Which of the following is NOT classified as an inhibitor of bacterial cell wall synthesis?

    <p>Fosfomycin</p> Signup and view all the answers

    Which antibiotic is considered a glycopeptide antibiotic?

    <p>Vancomycin</p> Signup and view all the answers

    What is the classification of cephadroxil, cephalexin, and cefazolin?

    <p>1st generation cephalosporins</p> Signup and view all the answers

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