10 Questions
In patients with hypertrophic cardiomyopathy experiencing persistent symptoms despite medical therapy, what is the preferred invasive treatment?
Surgical myectomy
Which medication is NOT recommended for patients with hypertrophic cardiomyopathy as it worsens outflow tract obstruction and does not relieve high end-diastolic pressure?
Nitrates
What is the effect of inotropic drugs on patients with hypertrophic cardiomyopathy?
Worsen outflow tract obstruction
When should an implantable cardioverter-defibrillator (ICD) usually be placed in patients with hypertrophic cardiomyopathy?
If they experience unexplained syncope
What is the mechanism of action of mavacamten in treating hypertrophic cardiomyopathy?
Reduces actin-myosin cross-bridge formation
Which type of medications are the mainstays for treating hypertrophic cardiomyopathy without obstruction?
Beta-blockers and heart rate-limiting calcium channel blockers
What is the purpose of slowing down the heart rate in hypertrophic cardiomyopathy treatment?
To prolong diastolic filling period
Which medication is most effective for patients with a resting gradient in hypertrophic cardiomyopathy?
Disopyramide
What is the role of disopyramide in treating hypertrophic cardiomyopathy?
Reduces outflow tract gradient through negative inotropic effects
In treating patients with obstructive hypertrophic cardiomyopathy, which medication is best at blunting the gradient occurring during exercise?
Beta-blockers
Test your knowledge on the treatment options for hypertrophic cardiomyopathy, including the use of beta-blockers, calcium channel blockers, mavacamten, and other medications. Learn about the importance of avoiding certain drugs like nitrates and ACE inhibitors, and when antiarrhythmics or implantable devices may be necessary.
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