MIcrobiology of Lower Lung Infection BMS

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Questions and Answers

What characteristic color does Streptococcus Pneumoniae alpha-hemolytic group produce on blood agar?

  • Greenish (correct)
  • Yellowish
  • Brownish
  • Reddish

Which term best describes the genus to which Streptococcus Pneumoniae belongs?

  • Streptococcus (correct)
  • Cocci
  • Gram-positive
  • Bacteria

What role do key antigens play in pneumococcal pathogenesis and virulence?

  • Increase bacterial replication
  • Enhance phagocytosis
  • Reduce capsule thickness
  • Promote immune evasion (correct)

What does the term 'Streptococcus' mean in Greek origin?

<p>Twisted (D)</p> Signup and view all the answers

How does Streptococcus Pneumoniae appear when growing on blood agar?

<p>Pairs (C)</p> Signup and view all the answers

What distinguishes staphylococci from streptococci based on morphology?

<p>Staphylococci appear in grapelike clusters, while streptococci are in chains. (D)</p> Signup and view all the answers

Which bacterium is known for producing catalase as a virulence factor?

<p>Staphylococcus aureus (C)</p> Signup and view all the answers

How are staphylococci and streptococci differentiated biochemically?

<p>By their production of catalase (B)</p> Signup and view all the answers

What is the main morphological difference between staphylococci and streptococci?

<p>Arrangement in chains vs. grapelike clusters (A)</p> Signup and view all the answers

Which bacterium is known for being nonmotile and not forming spores?

<p>S. Pneumoniae (B)</p> Signup and view all the answers

What is the primary structural feature that contributes to Klebsiella Pneumoniae's ability to cause necrotizing lobar pneumonia in compromised individuals?

<p>Capsule for protection (A)</p> Signup and view all the answers

Which bacterial strain is known to cause UTIs and bacteremia in hospitalized patients?

<p>Klebsiella Pneumoniae (C)</p> Signup and view all the answers

What is the common term for Legionella's atypical acute lobar pneumonia with multisystem symptoms?

<p>Legionnaires disease (D)</p> Signup and view all the answers

Which of the following bacterial strains is NOT classified as a typical cause of community-acquired pneumonia (CAP)?

<p>Legionella (D)</p> Signup and view all the answers

In terms of host defense mechanisms, which aspect of immunity constitutes the first line of defense against pathogens?

<p>Physical and chemical barriers (B)</p> Signup and view all the answers

Which serum protein reacts with the C-substance of S. pneumoniae?

<p>C-reactive protein (CRP) (D)</p> Signup and view all the answers

What is the function of Pneumolysin in S. pneumoniae pathogenesis?

<p>Causes red blood cell destruction (C)</p> Signup and view all the answers

How does IgA protease contribute to S. pneumoniae pathogenicity?

<p>Cleaves IgA to enhance colonization of mucosa (B)</p> Signup and view all the answers

During S. pneumoniae infection, what leads to the consolidation of the lung?

<p>Outpouring of fluid and blood cells (A)</p> Signup and view all the answers

Which type of protein is C-reactive protein (CRP) classified as?

<p>β-globulin (D)</p> Signup and view all the answers

What predisposing factor is most likely to lead to disease caused by pneumococci?

<p>Alcohol or drug intoxication (D)</p> Signup and view all the answers

Which of the following is NOT listed as a predisposing factor for pneumococcal disease?

<p>Healthy young age (C)</p> Signup and view all the answers

Which bacterial species is a normal component of the upper respiratory tract flora?

<p>Haemophilus influenzae (C)</p> Signup and view all the answers

What is the major cause of morbidity and mortality worldwide, resulting in 2.4 million cases and 160,000 deaths each year?

<p>Bordetella pertussis (C)</p> Signup and view all the answers

Which tissue or organ is typically affected by Pseudomonas aeruginosa infections following trauma?

<p>Eye (D)</p> Signup and view all the answers

What is the role of capsules in S. pneumoniae pathogenesis?

<p>Prevent phagocytosis by immune cells (A)</p> Signup and view all the answers

Which of the following best describes C-reactive protein (CRP) in pneumococcal infections?

<p>A marker for inflammation and infection (C)</p> Signup and view all the answers

Which virulence factor plays a key role in S. pneumoniae infections by inhibiting phagocytosis?

<p>Pili (A)</p> Signup and view all the answers

How do antigens of S. pneumoniae contribute to its virulence?

<p>They help the bacteria evade host defenses (B)</p> Signup and view all the answers

What role do exotoxins play in S. pneumoniae pathogenesis?

<p>Cause direct damage to host cells (C)</p> Signup and view all the answers

What is the most common cause of subacute bacterial endocarditis?

<p>S. viridans (D)</p> Signup and view all the answers

Which Streptococcus is the leading cause of neonatal sepsis and meningitis?

<p>S. agalactiae (group B Streptococcus) (B)</p> Signup and view all the answers

Which of the following diseases is not caused by S. pyogenes?

<p>Otitis media (B)</p> Signup and view all the answers

Which Streptococcus is the most common cause of community-acquired pneumonia?

<p>S. pneumoniae (A)</p> Signup and view all the answers

In pneumococcal infections, which structure helps the bacteria evade phagocytosis?

<p>Capsule (B)</p> Signup and view all the answers

Which organism is part of the normal flora of the human pharynx?

<p>S. viridans (C)</p> Signup and view all the answers

Which Streptococcus induces local tissue inflammation at the site of infection?

<p>S. pyogenes (group A Streptococcus) (D)</p> Signup and view all the answers

Which Streptococcus causes immunologic diseases such as rheumatic fever and acute glomerulonephritis?

<p>S. pyogenes (group A Streptococcus) (B)</p> Signup and view all the answers

What is the leading cause of pharyngitis among the given organisms?

<p>S. pyogenes (group A Streptococcus) (C)</p> Signup and view all the answers

Which Streptococcus causes scarlet fever and toxic shock syndrome?

<p>S. pyogenes (group A Streptococcus) (C)</p> Signup and view all the answers

What is the most common cause of subacute bacterial endocarditis?

<p>S. viridans (B)</p> Signup and view all the answers

Which Streptococcus species is the leading cause of neonatal sepsis and meningitis?

<p>S. agalactiae (B)</p> Signup and view all the answers

What is the typical presentation of Streptococcal infections known as pyogenic diseases?

<p>Local tissue inflammation at the site of infection (C)</p> Signup and view all the answers

Which Streptococcus species is associated with diseases involving widespread systemic symptoms in areas without localized organisms?

<p>S. pyogenes (A)</p> Signup and view all the answers

What is the main pathogenic mechanism of Staphylococcus aureus that leads to disseminated diseases?

<p>Production of exotoxins and enzymes (B)</p> Signup and view all the answers

Which enzyme produced by Staphylococcus aureus degrades many penicillins, leading to resistance against them?

<p>β-lactamase (C)</p> Signup and view all the answers

What is the main site of colonization for Staphylococcus aureus according to the provided text?

<p>Nose (B)</p> Signup and view all the answers

In the classification of Streptococci, which group does Streptococcus pneumoniae belong to?

<p>Alpha-hemolytic (B)</p> Signup and view all the answers

What role does Pneumolysin play in the pathogenesis of Staphylococcus aureus infections?

<p>Induction of tissue inflammation (C)</p> Signup and view all the answers

Which disseminated disease is commonly associated with Staphylococcus aureus infections?

<p>Osteomyelitis (A)</p> Signup and view all the answers

Which group of Streptococci is known to cause the most frequent bacterial cause of pharyngitis?

<p>Group A streptococci (D)</p> Signup and view all the answers

What is the characteristic hemolysis observed in α-hemolytic streptococci on blood agar plates?

<p>Green zone around colonies (D)</p> Signup and view all the answers

Which streptococci group is commonly found in the oropharynx?

<p>Group S streptococci (B)</p> Signup and view all the answers

What inhibits the growth of Group A streptococci (S.pyogenes) on agar plates in the laboratory?

<p>Bacitracin (C)</p> Signup and view all the answers

Which Streptococcus is primarily found in the vagina and colon?

<p>S. agalactiae (A)</p> Signup and view all the answers

What is the role of Enterotoxin produced by Staphylococcus aureus?

<p>Causes food poisoning (A)</p> Signup and view all the answers

Which pyogenic lesion is commonly associated with localized production of exfoliatin by Staphylococcus aureus?

<p>Impetigo (C)</p> Signup and view all the answers

Which Streptococcus species causes scarlet fever and toxic shock syndrome?

<p>S. pyogenes (A)</p> Signup and view all the answers

What is a common site for colonization by S. aureus among hospital personnel and patients?

<p>Skin (D)</p> Signup and view all the answers

Which disseminated disease is NOT caused by Staphylococcus aureus?

<p>Pneumonia (D)</p> Signup and view all the answers

What is the characteristic morphology of Staphylococcus aureus when observed microscopically?

<p>Cocci in irregular grapelike clusters (C)</p> Signup and view all the answers

Which enzyme, produced by Staphylococcus aureus, degrades hydrogen peroxide?

<p>Catalase (C)</p> Signup and view all the answers

Which of the following is a typical lesion caused by Staphylococcus aureus infections?

<p>Bullous impetigo (A)</p> Signup and view all the answers

How are staphylococci and streptococci differentiated biochemically in terms of catalase production?

<p>Staphylococci produce catalase, streptococci do not (D)</p> Signup and view all the answers

Which of the following diseases can be caused by disseminated Staphylococcus aureus infections?

<p>Scalded skin syndrome (D)</p> Signup and view all the answers

Which toxin produced by Staphylococcus aureus can cause toxic shock syndrome by stimulating T-cell proliferation and massive cytokine release?

<p>Enterotoxins (A)</p> Signup and view all the answers

What is a typical lesion caused by Staphylococcus aureus that involves the separation of the epidermal layer at the stratum granulosum, leading to the formation of blisters?

<p>Scalded skin syndrome (D)</p> Signup and view all the answers

Which classification of Streptococci is known for causing dental caries and endocarditis, and is commonly found in the oral cavity?

<p>Alpha-hemolytic Streptococci (D)</p> Signup and view all the answers

How does Staphylococcus aureus evade the host immune system by forming a protective barrier against phagocytosis?

<p>Forming capsule (C)</p> Signup and view all the answers

Which disseminated disease caused by Staphylococcus aureus is characterized by the formation of abscesses in various organs such as lungs, liver, and brain?

<p>Sepsis (B)</p> Signup and view all the answers

Which toxin produced by Staphylococcus aureus is known to combine with host cell membranes, forming pores that disrupt cellular functions?

<p>Alpha toxin (B)</p> Signup and view all the answers

Which of the following is a typical lesion caused by Staphylococcus aureus that is characterized by necrosis of subcutaneous tissue and is associated with diabetes?

<p>Necrotizing fasciitis (D)</p> Signup and view all the answers

Which classification of Streptococci describes the group that includes Streptococcus pneumoniae, known for causing pneumonia and meningitis?

<p>Alpha-hemolytic (D)</p> Signup and view all the answers

What is the mechanism through which Panton-Valentine leukocidin (PVL), produced by Staphylococcus aureus, contributes to pathogenesis?

<p>Forming pores in leukocytes (D)</p> Signup and view all the answers

Which of the following diseases results from disseminated Staphylococcus aureus infection involving the lungs, skin, and soft tissues?

<p>Necrotizing pneumonia (A)</p> Signup and view all the answers

What virulence factor produced by Staphylococcus aureus interferes with the host's immune response by inhibiting phagocytosis?

<p>Coagulase (D)</p> Signup and view all the answers

Which Streptococcus species is commonly associated with scarlet fever and toxic shock syndrome?

<p>Streptococcus pyogenes (C)</p> Signup and view all the answers

'Swimmer's ear' is a common infection caused by which pathogen typically found in the external ear canal?

<p>Pseudomonas aeruginosa (B)</p> Signup and view all the answers

What is the main role of IgA protease in the pathogenicity of Streptococcus pneumoniae infections?

<p>Degrading secretory IgA antibodies (A)</p> Signup and view all the answers

What is the key function of pneumolysin in Streptococcus pneumoniae pathogenesis?

<p>Disrupting host cell membranes and promoting inflammation (C)</p> Signup and view all the answers

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