Translation Initiation and Elongation

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What are the three steps involved in the translation process?

Initiation, elongation, and termination.

What is the definition of translation in the context of protein synthesis?

The synthesis of a protein molecule using mRNA as a template.

What is the function of the large subunit of a ribosome?

It has binding sites for tRNAs (A and P sites) and attaches to the small subunit and mRNA.

What is the role of the anticodon in tRNA?

It binds with a specific codon in mRNA by complementary base pairing.

What is carried by the 3'-end of tRNA?

An amino acid.

During the initiation stage of translation, what is the first amino acid that binds to the A-site?

Methionine (Met) in eukaryotes, or N-formylmethionine (fMet) in bacteria

What is the function of the release factor during the termination stage of translation?

To release the polypeptide from the ribosome

During the elongation stage, what is the process by which the polypeptide detaches from the tRNA in the P-site and binds to the amino acid and tRNA in the A-site?

Peptide bond formation

What is the role of the large ribosomal subunit during the initiation stage of translation?

To bind to the small ribosomal subunit to form a functional ribosome

What are the three stages of translation mentioned in the passage?

Initiation, elongation, and termination

Test your understanding of the translation process, including the initiation stage where mRNA binds to the ribosomal subunit, and the elongation stage where codon recognition occurs. Learn about the role of initiator tRNA, start codon, and the formation of the functional ribosome.

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