18 Questions
What is the main function of albumin in the body?
Controls oncotic pressure and serves as a transporter of substances
What are the two main causes of hypoalbuminemia?
Decreased albumin synthesis and increased losses of albumin
What is the only cause of hyperalbuminemia?
Dehydration
What is the role of prealbumin (transthyretin) in the body?
Transport protein for thyroid hormones and retinol (vitamin A)
What is the function of oncotic pressure in the body?
Maintains osmotic pressure of blood and prevents edema
What are some conditions that can lead to lower levels of prealbumin?
Liver disease, nephrotic syndrome, acute phase inflammatory response, and malnutrition
What is the role of Haptoglobin in the body?
Haptoglobin is a plasma glycoprotein that binds tightly to extra-corpuscular hemoglobin.
What is the consequence of a deficiency in ceruloplasmin levels?
A deficiency in ceruloplasmin leads to Wilson disease, a genetic disorder that causes a dangerous buildup of copper in the body.
What is the primary function of Transferrin in the body?
Transferrin plays a central role in iron metabolism and is responsible for delivering ferric ions.
How does Elevated maternal AFP levels relate to neural tube defects?
Elevated maternal AFP levels are associated with neural tube defects.
What can Decreased maternal AFP levels indicate?
Decreased maternal AFP levels are associated with an increased risk of Down’s syndrome.
How does Haptoglobin contribute to limiting iron losses in the body?
Haptoglobin prevents hemoglobin loss from the kidneys, thereby limiting iron losses.
What is the role of plasminogen in the body?
Plasminogen is an abundant plasma protein that, when converted to its active form plasmin, plays an essential role in fibrinolysis.
Explain the function of fibrinogen in hemostasis.
Fibrinogen acts as a substrate for thrombin to be converted into fibrin, which supports platelet aggregation and wound healing.
What is the primary function of ferritin in cells?
Ferritin is a protein that stores iron inside cells.
Describe the composition of hemosiderin and how it is formed.
Hemosiderin is an iron-storage complex composed of partially digested ferritin and lysosomes.
What is the main function of transferrin in the body?
Transferrin is a plasma protein that transports iron through the blood to various tissues.
How does the liver respond to inflammation in terms of C-reactive protein (CRP) production?
The liver releases more C-reactive protein into the bloodstream in response to inflammation in the body.
Test your knowledge on the functions of Transferrin, Ferritin, and Hemosiderin, which are important proteins involved in iron metabolism in the body. Learn about their roles in iron transport, storage, and utilization.
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