Transcription Factors and Enhancer-Promoter Interaction

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12 Questions

What is the role of General Transcription Factors in forming Enhancer-Promoter loops?

Mediating the interaction between the Enhancer and Promoter

How can mistakes in forming the BMP4 Enhancer-Promoter loop lead to webbing between digits in humans?

By causing cell death in the webbing cells

What is added to the 3' end of mRNA after introns are removed?

PolyA tail

Which region is present both upstream and downstream from the translated region of a gene?

UTR

What is the main function of 7-methyl Guanine in mRNA processing?

Protecting against degradation

Which factor determines the specificity of enhancer-promoter loop formation in different tissues?

General Transcription Factors

What is the function of TFs/GTF interaction in gene expression?

Enabling enhancer-promoter loop formation

What consequence can occur if there are mistakes in forming the BMP4 Enhancer-Promoter Loop?

Webbing between digits

What is the role of the 5'-cap, specifically 7methyl Guanine, in mRNA processing?

Protecting mRNA from degradation

What is the function of the polyA tail added to mRNA?

Marking the end of the mRNA molecule

During mRNA processing, what is the primary role of the spliceosome?

Remove introns from the pre-mRNA

Which region of a gene is not involved in transcription and contains untranslated sequences?

UTR region

Explore the connection between transcription factors and enhancer-promoter loop formation. Learn how errors can lead to significant consequences in gene transcription. Dive into the complex process of creating thousands of enhancer-promoter loops.

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