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Questions and Answers
What regulates the amount of zinc in enterocytes?
What regulates the amount of zinc in enterocytes?
- Metallothionein
- Synthesis of zinc
- Zinc transport proteins (correct)
- Intestinal lumen
What happens to zinc under high zinc intake?
What happens to zinc under high zinc intake?
- It is stored in metallothionein
- It is pumped out of the enterocyte (correct)
- It is transported into the blood stream
- It is synthesized into metallothionein
What regulates the amount of zinc that passes from the enterocyte into the blood?
What regulates the amount of zinc that passes from the enterocyte into the blood?
- Synthesis of zinc
- Intestinal lumen
- Zinc transport proteins
- Metallothionein (correct)
What happens to zinc when the mucosal cell dies?
What happens to zinc when the mucosal cell dies?
What is the role of metallothionein in zinc regulation?
What is the role of metallothionein in zinc regulation?
What prevents zinc from moving into the blood stream under high zinc intake?
What prevents zinc from moving into the blood stream under high zinc intake?
What is the function of zinc transport proteins in enterocytes?
What is the function of zinc transport proteins in enterocytes?
What happens to zinc under low zinc intake?
What happens to zinc under low zinc intake?
What is the role of metallothionein when zinc levels are high?
What is the role of metallothionein when zinc levels are high?
What happens to zinc within vesicles under high zinc intake?
What happens to zinc within vesicles under high zinc intake?
Which mineral plays a crucial role in protecting cells from free radical damage, DNA and RNA synthesis, and immune system function?
Which mineral plays a crucial role in protecting cells from free radical damage, DNA and RNA synthesis, and immune system function?
What can zinc deficiency lead to?
What can zinc deficiency lead to?
Which mineral is essential for energy production, connective tissue formation, and iron metabolism?
Which mineral is essential for energy production, connective tissue formation, and iron metabolism?
What is a symptom of copper deficiency?
What is a symptom of copper deficiency?
What is a characteristic feature of Wilson's disease?
What is a characteristic feature of Wilson's disease?
Which mineral is essential for amino acid, carbohydrate, and cholesterol metabolism, as well as cartilage formation and antioxidant protection?
Which mineral is essential for amino acid, carbohydrate, and cholesterol metabolism, as well as cartilage formation and antioxidant protection?
What can selenium deficiency lead to?
What can selenium deficiency lead to?
Which mineral is an essential component of selenoproteins, including glutathione peroxidases, thioredoxin reductases, and iodothyronine deiodinases?
Which mineral is an essential component of selenoproteins, including glutathione peroxidases, thioredoxin reductases, and iodothyronine deiodinases?
What can selenium toxicity cause?
What can selenium toxicity cause?
What affects the selenium content of plant foods?
What affects the selenium content of plant foods?
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Study Notes
Essential Trace Minerals: Zinc, Copper, Manganese, and Selenium
- In conditions of low zinc intake, more zinc is transported into the enterocyte than transported out, leading to reduced metallothionein production and potential zinc deficiency symptoms.
- Zinc plays a crucial role in various bodily functions, including protecting cells from free radical damage, DNA and RNA synthesis, and immune system function.
- Zinc deficiency can lead to symptoms such as poor growth, skin rashes, hair loss, and reduced immune function.
- Zinc toxicity can cause gastrointestinal irritation, vomiting, and headaches, and chronic toxicity can result in copper deficiency.
- Copper exists in +1 and +2 oxidation states and is essential for functions such as energy production, connective tissue formation, and iron metabolism.
- Copper deficiency can lead to symptoms such as anemia, bone abnormalities, and hypertriglyceridemia.
- Wilson's disease is a rare genetic disorder that results in copper overload and can cause characteristic Kayser-Fleischer rings in the eyes.
- Manganese is essential for various bodily functions, including amino acid, carbohydrate, and cholesterol metabolism, as well as cartilage formation and antioxidant protection.
- Selenium deficiency can lead to Keshan disease, affecting the heart muscle, and symptoms such as muscular discomfort and weakness.
- Selenium is an essential component of selenoproteins, including glutathione peroxidases, thioredoxin reductases, and iodothyronine deiodinases.
- Selenium toxicity can cause symptoms such as nausea, diarrhea, hair and nail changes, and fatigue, and in severe cases, it can lead to death.
- The selenium content of plant foods depends on the selenium content of the soil in which they are grown, and soil selenium levels can vary from deficient to very high.
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