Toxins and Staphylococcus Bacterial Toxins
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Questions and Answers

What are the three types of protein exotoxins mentioned in the text?

Type I toxins (Superantigens), Type II toxins (Membrane-disrupting toxins), Type III toxins (A-B toxins)

What are the three non-protein toxins mentioned in the text?

LPS (endotoxin), TA, and LTA

What is the function of LPS-binding protein?

It binds to CD14 receptor to trigger inflammatory cytokines

What are some of the consequences of endotoxin activation?

<p>Increased vascular permeability, activation of complement cascade, activation of coagulase cascade, decrease in blood pressure, organ failure, and acute respiratory distress syndrome (ARDS)</p> Signup and view all the answers

What is the main structural component of the cell envelope of Gram-negative bacteria?

<p>LPS complex</p> Signup and view all the answers

What are the two main types of toxins mentioned in the text?

<p>Protein exotoxins and non-protein toxins</p> Signup and view all the answers

What are the three subtypes of protein exotoxins mentioned in the text?

<p>Type I toxins (Superantigens)- Type II toxins (Membrane-disrupting toxins)- Type III toxins (A-B toxins)</p> Signup and view all the answers

What is the function of LPS (endotoxin) in Gram-negative bacteria?

<p>It is a structural component of the cell envelope of Gram-negative bacteria.</p> Signup and view all the answers

How do non-protein toxins such as LPS, TA, and LTA interact with the immune system?

<p>They interact with Toll-like receptors (TLRs) and trigger inflammatory responses.</p> Signup and view all the answers

What are some of the consequences of endotoxin activation?

<p>Activation of inflammatory cytokines, complement cascade, increased vascular permeability, coagulase cascade, formation of clots in small vessels, decrease in blood pressure, organ failure, and acute respiratory distress syndrome (ARDS).</p> Signup and view all the answers

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