Bacterial Toxins: Endotoxins and Exotoxins

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TOXINS Request signatures Powered by Z Luminsign LPS endotoxin common to all ______ bacteria

gram-negative

Protein exotoxins Produced by some Enterobacteriacea act on host cells by damaging membranes, inhibiting protein synthesis, or altering metabolic pathways causing cell death (cytotoxin) or a physiologic alteration. * Enterotoxins cause secretion and ______

diarrhea

Most Enterobacteriacea are primarily colonizers of the lower gastrointestinal tract of humans and animals. Many species found in nature and live freely. In humans, they are the major facultative components of the colonic bacterial flora. Also found in the female genital tract and on the ______.

skin

Most strongly associated with E coli, Shigella, and ______

Yersinia

Enterobacteriaceae are scant in the respiratory tract of healthy individuals. (Increase in hospitalized patients). Mostly found among the indigenous microbiota: Escherichia coli, klebsiella, proteus, and ______. normal flora

Enterobacter

Shigella and Salmonella typhi: are strict human pathogens with no animal ______.

reservoir

Most Enterobacteriaceae are considered part of the normal flora in the respiratory tract of healthy individuals.

False

Enterobacteriaceae are primarily colonizers of the upper gastrointestinal tract of humans and animals.

False

Salmonella and Shigella species are considered members of the indigenous microbiota in humans.

False

P pili bind to bind to digalactoside (Gal-Gal) moieties on ______ cells.

kidney

The receptor(s) for the enteric pili include glycolipids and glycoproteins on the ______ surface.

enterocyte

Pili of diarrhea strains bind ______.

enterocytes

Test your knowledge about bacterial toxins, including endotoxins common to all gram-negative bacteria and exotoxins produced by some Enterobacteriaceae. Learn about the effects of exotoxins on host cells and their association with specific bacteria like E. coli, Shigella, and Yersinia.

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