Podcast
Questions and Answers
Why are geriatric patients often excluded from clinical trials in toxicology?
Why are geriatric patients often excluded from clinical trials in toxicology?
- Due to their decreased morbidity and mortality rates from poisoning.
- As a result of their increased morbidity and mortality rates from poisoning. (correct)
- Because they require lower doses of medications with narrow therapeutic index.
- Because they have faster clearance of drugs and toxins.
What physiological changes in the elderly contribute to prolonged toxic effects of drugs and toxins?
What physiological changes in the elderly contribute to prolonged toxic effects of drugs and toxins?
- Slower clearance of drugs and toxins due to reduced renal and hepatic function. (correct)
- Rapid clearance of drugs and toxins.
- Increased renal and hepatic function.
- Enhanced cognitive function.
In what way can cognitive and physical impairment in the elderly lead to accidental poisoning?
In what way can cognitive and physical impairment in the elderly lead to accidental poisoning?
- By enhancing the elimination of toxins.
- By increasing the absorption of drugs.
- By reducing medication errors.
- By causing medication errors or misdiagnosed therapeutic agents. (correct)
How do pharmacokinetic changes in pregnancy impact the toxicokinetics of poisons?
How do pharmacokinetic changes in pregnancy impact the toxicokinetics of poisons?
Why might specific antidotes require different dosing regimens in pregnant patients?
Why might specific antidotes require different dosing regimens in pregnant patients?
Why does physostigmine have a narrowed range of safety in pregnancy?
Why does physostigmine have a narrowed range of safety in pregnancy?
What is the main reason for avoiding the use of certain drugs in cases of anticholinergic poisoning during pregnancy?
What is the main reason for avoiding the use of certain drugs in cases of anticholinergic poisoning during pregnancy?
Why is the risk of drug-induced developmental abnormalities highest during early gestational months?
Why is the risk of drug-induced developmental abnormalities highest during early gestational months?
What contributes to the increased risk of toxicity in geriatric patients?
What contributes to the increased risk of toxicity in geriatric patients?
Why do common medications with a low therapeutic index pose a risk to geriatric patients?
Why do common medications with a low therapeutic index pose a risk to geriatric patients?
What is a common factor contributing to toxicity in geriatric patients taking non-steroidal anti-inflammatories?
What is a common factor contributing to toxicity in geriatric patients taking non-steroidal anti-inflammatories?
Why is it important for medical consultants to understand the impact of comorbid conditions on poisoning?
Why is it important for medical consultants to understand the impact of comorbid conditions on poisoning?
What percentage of adults aged 60 and older in the United States has at least one chronic disease?
What percentage of adults aged 60 and older in the United States has at least one chronic disease?
How do comorbid illnesses impact the outcome of a primary illness?
How do comorbid illnesses impact the outcome of a primary illness?
What should be considered when deciding to use a drug therapy during pregnancy?
What should be considered when deciding to use a drug therapy during pregnancy?
What makes geriatric patients more susceptible to adverse reactions or intentional overdoses with medications?
What makes geriatric patients more susceptible to adverse reactions or intentional overdoses with medications?
