Topical Drug Delivery Systems Quiz
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Questions and Answers

What are ointments, creams, and gels primarily intended for?

  • Topical application (correct)
  • Oral ingestion
  • Inhalation
  • Intravenous application
  • Which of the following is NOT a topical drug delivery system?

  • Injection (correct)
  • Plaster
  • Tincture
  • Lotion
  • What are unmedicated ointments primarily used for?

  • Physical effects as protectants (correct)
  • Oral ingestion
  • Systemic drug delivery
  • Intramuscular injection
  • Which type of ointment base is also termed hydrocarbon bases?

    <p>Oleaginous bases</p> Signup and view all the answers

    Where are ointments intended to be applied?

    <p>Externally</p> Signup and view all the answers

    What are topical drug delivery systems NOT typically used for?

    <p>Intramuscular injection</p> Signup and view all the answers

    Which type of ointment base is difficult to wash off from the skin?

    <p>Hydrocarbon bases</p> Signup and view all the answers

    What type of emulsion do water-removable bases resemble?

    <p>Oil-in-water emulsions</p> Signup and view all the answers

    Which substance can be used as a levigating agent for incorporating powdered substances into hydrocarbon bases?

    <p>Liquid petrolatum (mineral oil)</p> Signup and view all the answers

    What is the general formula for Hydrophilic Ointment, USP?

    <p>Stearyl alcohol, white petrolatum, methylparaben, propylparaben, sodium lauryl sulfate, propylene glycol, purified water</p> Signup and view all the answers

    What is the main characteristic of water-soluble bases?

    <p>They are completely water washable</p> Signup and view all the answers

    What factor does the selection of the ointment base depend on?

    <p>All of the above</p> Signup and view all the answers

    How are ointments mainly prepared?

    <p>Both incorporation and fusion methods</p> Signup and view all the answers

    What is the function of liquid petrolatum (mineral oil) in incorporating powdered substances into hydrocarbon bases?

    <p>Acting as a levigating agent</p> Signup and view all the answers

    Which type of base allows for the incorporation of additional quantities of aqueous solutions?

    <p>Absorption bases</p> Signup and view all the answers

    What is the primary advantage of water-removable bases?

    <p>They are easily washed from skin</p> Signup and view all the answers

    Which type of ointment base is difficult to wash off from the skin?

    <p>Oleaginous bases</p> Signup and view all the answers

    What factor does the selection of the ointment base depend on?

    <p>Physical effects provided</p> Signup and view all the answers

    What is the main characteristic of water-soluble bases?

    <p>They allow easy incorporation of aqueous solutions</p> Signup and view all the answers

    What is the function of liquid petrolatum (mineral oil) in incorporating powdered substances into hydrocarbon bases?

    <p>To aid in uniform mixing</p> Signup and view all the answers

    What type of emulsion do water-removable bases resemble?

    <p>Oil-in-water emulsion</p> Signup and view all the answers

    What are unmedicated ointments primarily used for?

    <p>As protectants, emollients, or lubricants</p> Signup and view all the answers

    What is the primary function of water-removable bases?

    <p>To allow for easy washing from the skin</p> Signup and view all the answers

    Which type of base permits the incorporation of additional quantities of aqueous solutions?

    <p>Absorption bases</p> Signup and view all the answers

    What is the main characteristic of water-soluble bases?

    <p>They are completely water washable</p> Signup and view all the answers

    Which substance can be used as a levigating agent for incorporating powdered substances into hydrocarbon bases?

    <p>Liquid petrolatum (mineral oil)</p> Signup and view all the answers

    What are ointments primarily intended for?

    <p>To release drug substances from the base</p> Signup and view all the answers

    What is the general formula for the preparation of 1,000 g of PEG ointment?

    <p>PEG 3350 --- 400 g, PEG 400 ---- 600 g</p> Signup and view all the answers

    What factor does the selection of the ointment base depend on?

    <p>The desirability of topical or percutaneous drug absorption</p> Signup and view all the answers

    How are water-removable bases best described?

    <p>As easily washed from skin because the external phase of the emulsion is aqueous</p> Signup and view all the answers

    What is a notable characteristic of absorption bases?

    <p>They result in oil-in-water emulsions when aqueous solutions are incorporated</p> Signup and view all the answers

    What is a major factor in selecting a base for ointment formulation?

    <p>The stability of the drug in the ointment base</p> Signup and view all the answers

    Study Notes

    Ointments and Topical Drug Delivery Systems

    • Ointments, creams, and gels are primarily intended for topical application to the skin or mucous membranes.

    Characteristics of Ointment Bases

    • Hydrocarbon bases are also termed hydrocarbon bases.
    • Water-soluble bases are characterized by being easily washed off from the skin.
    • Absorption bases are able to absorb and hold a large amount of water.
    • Water-removable bases are difficult to wash off from the skin, resemble oil-in-water emulsions, and permit the incorporation of additional quantities of aqueous solutions.
    • Hydrocarbon bases are difficult to wash off from the skin.

    Functions and Uses

    • Unmedicated ointments are primarily used for protecting and moisturizing the skin.
    • Water-removable bases are used for incorporating powdered substances and have the primary function of being easily removable from the skin.
    • Liquid petrolatum (mineral oil) is used as a levigating agent for incorporating powdered substances into hydrocarbon bases.

    Preparation and Formulation

    • Ointments are mainly prepared by incorporating active ingredients into a suitable base.
    • The general formula for Hydrophilic Ointment, USP is not specified, but the general formula for 1,000 g of PEG ointment is not provided.
    • The selection of the ointment base depends on the type of skin, the condition being treated, and the desired release of the active ingredient.

    Topical Drug Delivery Systems

    • Topical drug delivery systems are not typically used for treating systemic diseases.
    • They are used for delivering drugs directly to the skin or mucous membranes.

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    Description

    Test your knowledge of topical drug delivery systems including ointments, creams, gels, and more. Explore the characteristics and applications of various topical dosage forms used for medical treatment.

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