Topical Anti-Infectives in Skin Infections

The epidermis is the outermost layer of the skin that forms a barrier between the external and internal environment, protecting the body from injury, damage, heat, cold, chemicals, UV-radiation, and microorganisms.

Topical antiseptics reduce the growth of microorganisms, while germicides kill them. Both prevent infection by reducing the number of microorganisms on the skin.

Topical anti-psoriatics are medications applied directly to the skin to treat psoriasis. They help reduce inflammation, slow down skin cell growth, and relieve symptoms.

<p>Potential adverse reactions to topical drugs include skin irritation, allergic reactions, and systemic absorption. They can be minimized by using the correct dosage, avoiding sensitive areas, and monitoring for side effects.</p> Signup and view all the answers

<p>Topical enzymes break down dead skin cells, remove dead tissue, and promote wound healing. They work by catalyzing chemical reactions that break down proteins and other molecules.</p> Signup and view all the answers

<p>Topical antifungals exert their local effect by inhibiting the growth of fungi. Examples include Amphotericin B and Miconazole.</p> Signup and view all the answers

<p>Topical antivirals inhibit viral replication. Examples include Acyclovir and penciclovir.</p> Signup and view all the answers

<p>An antiseptic is a drug that stops, slows, or prevents the growth of microorganisms, while a germicide is a drug that kills microorganisms. Their mechanism of action is not well understood, but they affect a variety of microorganisms.</p> Signup and view all the answers

<p>Common adverse reactions include skin rash, itching, dermatitis, irritation, redness, and hypersensitivity.</p> Signup and view all the answers

<p>Mild and transient pain, numbness, and dermatitis.</p> Signup and view all the answers

<p>Topical antipsoriatics help to remove the plaques.</p> Signup and view all the answers

<p>They temporarily inhibit the conduction of nerve impulses from sensory nerve fibers.</p> Signup and view all the answers

<p>Local irritation, dermatitis, rash, burning sensation, stinging, and tenderness.</p> Signup and view all the answers

<p>To treat psoriasis, a chronic skin disease.</p> Signup and view all the answers

<p>By increasing the loss of bile acids, inhibiting the manufacture of cholesterol, and causing the breakdown of cholesterol.</p> Signup and view all the answers

<p>LDL transports cholesterol to cells and releases excess cholesterol into the blood, contributing to hyperlipidemia.</p> Signup and view all the answers

<p>Thrombosis is the formation of a clot in a blood vessel, while embolism occurs when the clot breaks loose and blocks a smaller vessel.</p> Signup and view all the answers

<p>Constipation, hemorrhoids, vitamin A and D deficiencies, reduced vitamin K, and abdominal pain.</p> Signup and view all the answers

<p>By reducing LDL and total cholesterol levels, which can help to prevent the formation of blood clots and reduce the risk of cardiovascular disease.</p> Signup and view all the answers

<p>The primary function of the cardiovascular system is to supply oxygen and nutrients to body tissues and remove toxic waste products. It maintains homeostasis by regulating body temperature and ensuring proper circulation of blood throughout the body.</p> Signup and view all the answers

<p>Anti-Hyperlipidemic drugs are medications that help in reducing cholesterol levels by inhibiting the production of cholesterol in the liver or increasing the excretion of cholesterol from the body.</p> Signup and view all the answers

<p>Anticoagulants are medications that prevent blood clotting by inhibiting the production of clotting factors in the liver or by blocking the action of clotting factors.</p> Signup and view all the answers

<p>Thrombolytic drugs are medications that dissolve blood clots by activating the body's natural clot-dissolving mechanisms. They work by converting plasminogen to plasmin, which breaks down fibrin clots.</p> Signup and view all the answers

<p>Vitamin deficiencies, particularly vitamin D and B12 deficiencies, have been linked to an increased risk of cardiovascular diseases. Vitamin supplements can help prevent cardiovascular diseases by reducing inflammation, improving blood vessel function, and regulating blood pressure.</p> Signup and view all the answers

<p>Cardiotonics increase and improve the contraction of the heart muscle to treat Heart failure. Common adverse reactions include nausea and vomiting, headache and visual disturbance, and mental depression.</p> Signup and view all the answers

<p>Antiarrhythmic drugs restore normal cardiac function and prevent arrhythmias. Potential adverse reactions include weakness, hypotension, and drowsiness.</p> Signup and view all the answers

<p>Atherosclerosis is the deposition of fatty plaques on the inner wall of arteries. Peripheral vasodilators treat this condition by dilating blood vessels and improving blood flow.</p> Signup and view all the answers

<p>Anti-hypertensive drugs are used to treat hypertension by reducing blood pressure. The primary benefit of using these drugs is to reduce the risk of cardiovascular disease and stroke.</p> Signup and view all the answers

<p>Cardiotonics increase the contraction of the heart muscle to treat heart failure, while antiarrhythmic drugs restore normal cardiac function to treat cardiac arrhythmias.</p> Signup and view all the answers

<p>Dilate the blood vessels</p> Signup and view all the answers

<p>Increase the risk of heart disease, congestive heart failure, kidney disease, blindness, and stroke</p> Signup and view all the answers

<p>Lower blood pressure by dilating or increasing the size of arteries</p> Signup and view all the answers

<p>Increased pulse rate</p> Signup and view all the answers

<p>Normal blood pressure: Systolic pressure &lt; 120mmHg and Diastolic pressure &lt; 80 mmHg (120/80mmHg). Hypertension: Systolic pressure &gt; 140 mmHg and Diastolic pressure &gt; 90 mmHg (140/90 mmHg)</p> Signup and view all the answers

<p>The primary function of the cardiovascular system is to supply oxygen and nutrients to body tissues and remove toxic waste products. It regulates body temperature by transporting heat from the core of the body to the skin, where it can be lost.</p> Signup and view all the answers

<p>Cardiotonics increase the heart's contractility and improve cardiac output, helping to alleviate symptoms of CHF. They can also reduce the heart's workload and improve patient exercise tolerance.</p> Signup and view all the answers

<p>Antiarrhythmic drugs help restore a normal heart rhythm by stabilizing the heart's electrical activity. Benefits include improved cardiac function and reduced risk of stroke. Risks include proarrhythmic effects, where the drug can worsen the arrhythmia.</p> Signup and view all the answers

<p>Peripheral vasodilators relax blood vessels, improving blood flow and reducing blood pressure. This helps to alleviate symptoms of atherosclerosis, such as claudication and angina.</p> Signup and view all the answers

<p>Anticoagulants prevent blood clotting disorders by inhibiting thrombus formation. Benefits include reduced risk of stroke and pulmonary embolism. Risks include bleeding complications.</p> Signup and view all the answers

<p>Cardiotonics increase and improve the contraction of the heart muscle to treat heart failure. They work by increasing the contraction of the heart muscle.</p> Signup and view all the answers

<p>Antiarrhythmic drugs restore normal cardiac function by correcting irregular heart rhythms. Adverse reactions include weakness, hypotension, and drowsiness.</p> Signup and view all the answers

<p>Atherosclerosis is the deposition of fatty plaques on the inner walls of arteries. Peripheral vasodilators treat this condition by dilating blood vessels and improving blood flow.</p> Signup and view all the answers

<p>Cardiotonics increase the contraction of the heart muscle to treat heart failure, while antiarrhythmic drugs restore normal cardiac function by correcting irregular heart rhythms.</p> Signup and view all the answers

<p>Anti-hypertensive drugs lower blood pressure to treat hypertension. The benefits of using these drugs include reducing the risk of cardiovascular disease and stroke.</p> Signup and view all the answers

<p>Untreated hypertension causes the heart to work too hard, increasing the risk of heart disease, congestive heart failure, kidney disease, blindness, and stroke.</p> Signup and view all the answers

<p>Peripheral vasodilators treat atherosclerosis by dilating the blood vessels, which increases blood flow and oxygen delivery to the affected areas, reducing the risk of heart disease and other complications.</p> Signup and view all the answers

<p>Anti-hypertensive drugs work by dilating or increasing the size of arteries (vasodilation), lowering blood pressure and reducing the risk of heart disease and other complications.</p> Signup and view all the answers

<p>Vasodilating drugs dilate blood vessels, reducing blood pressure and the risk of heart disease, congestive heart failure, kidney disease, blindness, and stroke.</p> Signup and view all the answers

<p>Hypertension causes the heart to work too hard, increasing the risk of heart disease, congestive heart failure, kidney disease, blindness, and stroke.</p> Signup and view all the answers

<p>The primary function of the cardiovascular system is to supply oxygen and nutrients to body tissues and remove toxic waste products from body tissues, thereby maintaining homeostasis in the body.</p> Signup and view all the answers

<p>Cardiotonics, such as digoxin, work by increasing the contractility of the heart, reducing the heart rate, and increasing the force of contraction, thereby improving cardiac function in CHF patients. The potential benefits include improved cardiac output, reduced symptoms, and decreased mortality.</p> Signup and view all the answers

<p>Antiarrhythmic drugs, such as beta blockers and amiodarone, work by regulating the heart rhythm, reducing the risk of sudden cardiac death, and improving symptoms in patients with cardiac arrhythmias. The potential benefits include reduced mortality, improved quality of life, and reduced symptoms, while the potential risks include proarrhythmia, bradycardia, and worsening of heart failure.</p> Signup and view all the answers

<p>Peripheral vasodilators, such as nitrates, work by dilating blood vessels, reducing blood pressure, and improving blood flow to the peripheral tissues, thereby improving symptoms in patients with atherosclerosis. The potential benefits include reduced symptoms, improved quality of life, and reduced risk of cardiovascular events.</p> Signup and view all the answers

<p>Antihypertensive drugs, such as diuretics, beta blockers, and ACE inhibitors, work by reducing blood pressure, reducing the risk of cardiovascular events, and improving cardiovascular outcomes in patients with hypertension. The potential benefits include reduced risk of cardiovascular events, improved quality of life, and reduced mortality.</p> Signup and view all the answers

<p>Cardiotonics increase and improve the contraction of the heart muscle, which helps to treat Heart Failure by increasing the heart's ability to pump enough blood to the body tissues.</p> Signup and view all the answers

<p>Cardiac arrhythmias are disturbed or irregular heart rates or rhythms, and antiarrhythmic drugs are used to treat these conditions by restoring normal cardiac function and preventing arrhythmias.</p> Signup and view all the answers

<p>Peripheral vasodilators are used to treat atherosclerosis by increasing blood flow to the body tissues, which helps to improve blood vessel function and reduce the symptoms of atherosclerosis.</p> Signup and view all the answers

<p>Anti-hypertensive drugs are used to treat hypertension by reducing blood pressure, which helps to reduce the risk of cardiovascular disease, such as heart failure, cardiac arrhythmias, and atherosclerosis.</p> Signup and view all the answers

<p>Cardiac arrhythmias can increase the risk of myocardial infarction, and antiarrhythmic drugs are used to treat cardiac arrhythmias and prevent myocardial infarction by restoring normal cardiac function and preventing arrhythmias.</p> Signup and view all the answers

<p>Cardiotonics increase and improve the contraction of the heart muscle, treating Heart Failure by increasing the heart's pumping efficiency.</p> Signup and view all the answers

<p>Antiarrhythmic drugs restore normal cardiac function by restoring normal heart rhythm and preventing arrhythmias.</p> Signup and view all the answers

<p>The primary function of the cardiovascular system is to supply oxygen and nutrients to body tissues and remove toxic waste products. It maintains homeostasis by regulating body temperature and supplying oxygen and nutrients to body tissues.</p> Signup and view all the answers

<p>Peripheral vasodilators treat atherosclerosis by widening blood vessels, improving blood flow, and reducing blood pressure, which can help prevent cardiovascular disease.</p> Signup and view all the answers

<p>Cardiotonics improve cardiac function by increasing the force of contraction of the heart, increasing cardiac output, and reducing the workload of the heart. The potential benefits include increased exercise tolerance, reduced symptoms, and improved survival rates.</p> Signup and view all the answers

<p>Antiarrhythmic drugs work by stabilizing the cardiac membrane, reducing abnormal impulse formation, and suppressing abnormal conduction pathways. The potential benefits include restoration of normal cardiac rhythm, reduced symptoms, and improved survival rates. The potential risks include proarrhythmia, torsades de pointes, and cardiovascular collapse.</p> Signup and view all the answers

<p>Anti-hypertensive drugs prevent cardiovascular disease by reducing blood pressure, reducing the risk of heart disease, and improving overall cardiovascular health.</p> Signup and view all the answers

<p>Antihypertensive drugs reduce blood pressure, reducing the risk of cardiovascular disease, heart failure, and stroke. The potential benefits include reduced cardiovascular morbidity and mortality, and improved survival rates. The potential risks include hypotension, dizziness, and electrolyte imbalance.</p> Signup and view all the answers

<p>Cardiotonics increase heart contraction, treating Heart Failure, while antiarrhythmic drugs restore normal heart rhythm, treating cardiac arrhythmias.</p> Signup and view all the answers

<p>Peripheral vasodilators dilate blood vessels, reducing peripheral resistance and improving blood flow to affected areas. The potential benefits include improved exercise tolerance, reduced symptoms, and improved survival rates.</p> Signup and view all the answers

<p>Untreated hypertension can cause the heart to work too hard, increasing the risk of heart disease, congestive heart failure, kidney disease, blindness, and stroke.</p> Signup and view all the answers

<p>Vasodilating drugs work by dilating or increasing the size of arteries, which lowers blood pressure. Their mechanism of action involves vasodilation.</p> Signup and view all the answers

<p>The primary function of antihypertensive drugs is to reduce blood pressure. They work by dilating or increasing the size of arteries, increasing sodium excretion, or inhibiting the action of angiotensin-converting enzyme.</p> Signup and view all the answers

<p>Atherosclerosis is a disease characterized by the narrowing of the lumen of the artery. Peripheral vasodilators treat atherosclerosis by dilating the blood vessels, improving blood vessel function, and reducing symptoms.</p> Signup and view all the answers

<p>The normal range of blood pressure is systolic pressure less than 120mmHg and diastolic pressure less than 80mmHg. Hypertension is defined as systolic pressure above 140mmHg and diastolic pressure above 90mmHg.</p> Signup and view all the answers