Connective Tissue
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Connective Tissue

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Questions and Answers

What does this image show and give a description of the tissue.

Mesenchyme: population of undifferentiated cells, usually elongated mesenchymal cells surrounded by extracellular matrix that they produce.

This picture depicts the cellular and extracellular components of connective tissue

True

Mesenchymal cells are ____.

Undifferentiated

What is the meaning of multipotent?

<p>The ability to differentiate into multiple cell types</p> Signup and view all the answers

Functions of connective tissue

<p>Mechanical support for other tissues, communication and transport among other tissues</p> Signup and view all the answers

What type of cells involved in immunological defense are found within the connective tissue?

<p>Principal cells</p> Signup and view all the answers

Connective tissue are derived from _______ _______, a tissue developing mainly from middle layer of embryo, or mesoderm.

<p>Embryonic mesenchyme</p> Signup and view all the answers

They migrate from _____, surrounding and penetrating organs.

<p>site of origin in the embryo</p> Signup and view all the answers

What are some examples of adult connective tissues that mesenchymal cells persist in?

<p>Tooth, pulp and adipose tissue</p> Signup and view all the answers

What are the components of connective tissue?

<p>Cells, extracellular matrix, ground substance and fibres</p> Signup and view all the answers

What are the 3 types of connective tissue?

<p>Embryonic, proper and special</p> Signup and view all the answers

Components of connective tissue

<p>Extracellular matrix consists of connective tissue fluid which are embedded in different fibres = Ground substance Where cells are scattered = Extracellular matrix Pliable connective tissue = What the interaction of the fibres, extracellular matrix and water form Cells and extracellular matrix = 2 main components of connective tissue</p> Signup and view all the answers

Connective tissue cell lineage

<p>Fibroblasts and fibrocytes, adipocytes (fat cells), mast cells, macrophages, plasma cells and leukocytes</p> Signup and view all the answers

Cell types

<p>Read pic</p> Signup and view all the answers

What are the most common cell types in connective tissue?

<p>Fibroblasts and fibrocytes</p> Signup and view all the answers

What are the 2 main components of connective tissue?

<p>Cells and extracellular matrix</p> Signup and view all the answers

Study Notes

Connective Tissue Overview

  • Connective tissue consists of cellular and extracellular components that support, bind, and protect other tissues and organs.
  • Mesenchymal cells are multipotent stem cells capable of differentiating into different types of connective tissue cells.
  • "Multipotent" refers to the ability of these cells to evolve into multiple cell types within a specific lineage.

Functions of Connective Tissue

  • Connective tissue plays vital roles in structural support, nutrient storage, immune defense, and serving as a medium for circulation.
  • Key immunological defense cells found in connective tissue include macrophages, mast cells, and lymphocytes.

Origin and Development

  • Derived from mesenchyme, which is the embryonic tissue primarily from the mesoderm (middle layer of the embryo).
  • These cells migrate from the original germ layers, surrounding and penetrating developing organs during embryonic development.

Adult Connective Tissues

  • Examples of adult tissues where mesenchymal cells persist include adipose tissue, cartilage, and bone marrow.
  • Mesenchymal stem cells reside in niches within these adult connective tissues, providing potential for regeneration.

Components of Connective Tissue

  • Composed of cells (such as fibroblasts, adipocytes, and immune cells), fibers (including collagen, elastin, and reticular fibers), and ground substance (the non-cellular material surrounding cells).
  • The matrix, made up of ground substance and fibers, is critical for tissue function and structure.

Types of Connective Tissue

  • Three major types of connective tissue:
    • Loose connective tissue (e.g., areolar tissue)
    • Dense connective tissue (e.g., tendons and ligaments)
    • Specialized connective tissue (e.g., blood, bone, cartilage)

Cell Types

  • Most common cell types include fibroblasts, adipocytes, immune cells (e.g., mast cells and macrophages), and chondrocytes in cartilage.
  • Each cell type plays a unique role in tissue integrity, metabolism, and immune response.

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Histology (MBBS)

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