Tissue Conjonctif Biology

Tissue Conjonctif

• A type of supportive tissue that provides a framework for other tissues and organs to function properly.

Definition

• Structurally, composed of cells, fibers, and a fundamental substance that provides a framework.
• Functionally, fills the space between organs and tissues, providing a connection and support system.

Embryonic Origin

• Originates from the mesoblast, a type of embryonic tissue.
• Mesoblast differentiates into mesenchymal cells, which then differentiate into various types of cells.

Characteristics

• Star-shaped cell structure with cytoplasmic extensions.
• Semi-solid substance that provides a framework.
• Functional role in providing a connection and support system.

Functions

• Crucial role in connecting organs and tissues, providing a framework.
• Provides a pathway for nutrients and waste products.
• Plays a role in the immune system, providing a defense against pathogens.

Pathological Role

• Plays a significant role in inflammation, a response to tissue injury or infection.
• Inflammation involves the activation of various cells and molecules, including macrophages, lymphocytes, and cytokines.
• Affected by inflammation, leading to changes in its structure and function.

Classification

• Classified into different types based on the presence of certain cells and fibers.
• Main types: Fibroblastic, Chondroblastic, and Osteoblastic Tissue Conjonctif.

Histological Study

• Studied using histological techniques, such as staining and microscopy.
• Most common staining technique: H&E (Hematoxylin and Eosin) stain.

Cell Types

• Composed of various cell types, including:
  • Fibroblasts: produce collagen fibers.
  • Chondroblasts: produce cartilage fibers.
  • Osteoblasts: produce bone fibers.
  • Macrophages: play a role in the immune system.
  • Lymphocytes: play a role in the immune system.
  • Mast cells: play a role in the immune system.
  • Giant cells: formed by the fusion of multiple macrophages.

Fibroblasts

• Important cell type in connective tissue.
• Function: produce fibers and substance fundamental to form connective tissue.
• Characteristics: star-shaped or fusiform, nucleus is not mytotic, cytoplasm is basophilic, RER is well-developed, and synthesizes proteins for fibers and substance fundamental.
• Role: in immune response, synthesizes cytokines for inflammation and immune response.

Adipocytes

• Specialized cells for storing fat.
• Two types: primary (brown fat) and secondary (white fat).
• Primary Adipocytes: polygonal shape, nucleus is central, multiple lipid vacuoles, multiple mitochondria, and function to produce heat.