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Questions and Answers
What typically triggers the spontaneous resolution of molluscum lesions?
What typically triggers the spontaneous resolution of molluscum lesions?
- Removal by scraping
- Strengthening of the immune system (correct)
- Exposure to liquid nitrogen
- Application of topical treatments
Which HPV type is primarily associated with causing plantar warts?
Which HPV type is primarily associated with causing plantar warts?
- HPV 3
- HPV 1 (correct)
- HPV 2
- HPV 16
What is the hallmark characteristic of warts?
What is the hallmark characteristic of warts?
- Rough, verrucous surface with black dots (correct)
- Presence of clear fluid sacs
- Smooth surface with no pigmentation
- Large, scaly patches without pigmentation
Which treatment methods are effective for periungual warts?
Which treatment methods are effective for periungual warts?
Which of the following HPV proteins is known to degrade p53?
Which of the following HPV proteins is known to degrade p53?
What does the presence of black dots under a wart indicate?
What does the presence of black dots under a wart indicate?
Why can treating periungual warts be particularly difficult?
Why can treating periungual warts be particularly difficult?
What role do the early HPV proteins E6 and E7 play in the context of the virus?
What role do the early HPV proteins E6 and E7 play in the context of the virus?
What is the most common causative organism of tinea capitis?
What is the most common causative organism of tinea capitis?
Which of the following statements about tinea corporis is correct?
Which of the following statements about tinea corporis is correct?
Which of the following best describes the scaling seen in tinea infections?
Which of the following best describes the scaling seen in tinea infections?
In darkly pigmented children, tinea corporis may show which of the following changes?
In darkly pigmented children, tinea corporis may show which of the following changes?
What type of fungi causes both tinea capitis and tinea corporis?
What type of fungi causes both tinea capitis and tinea corporis?
Which area of the body is typically NOT affected by tinea corporis?
Which area of the body is typically NOT affected by tinea corporis?
What is the primary method used to diagnose tinea infections?
What is the primary method used to diagnose tinea infections?
The ring shape seen in tinea corporis is primarily due to which phenomenon?
The ring shape seen in tinea corporis is primarily due to which phenomenon?
What is the primary cause of varicella?
What is the primary cause of varicella?
What distinguishes varicella from smallpox regarding the appearance of lesions?
What distinguishes varicella from smallpox regarding the appearance of lesions?
What is a common method of transmission for lice?
What is a common method of transmission for lice?
Which treatment can significantly lessen the severity of varicella if administered early?
Which treatment can significantly lessen the severity of varicella if administered early?
How long can it take for hypersensitivity to lice saliva to develop?
How long can it take for hypersensitivity to lice saliva to develop?
What is the characteristic feature of adult lice when identified?
What is the characteristic feature of adult lice when identified?
Within how many hours must varicella immune-globulin be administered after exposure for it to be effective?
Within how many hours must varicella immune-globulin be administered after exposure for it to be effective?
What is a potential outcome for individuals immunized against varicella who still contract the disease?
What is a potential outcome for individuals immunized against varicella who still contract the disease?
What is the characteristic appearance of the rash associated with Fifth Disease?
What is the characteristic appearance of the rash associated with Fifth Disease?
Which virus is primarily responsible for causing Roseola?
Which virus is primarily responsible for causing Roseola?
What triggers the appearance of the rash in Fifth Disease?
What triggers the appearance of the rash in Fifth Disease?
In what timeframe does the generalized rash of Fifth Disease typically last?
In what timeframe does the generalized rash of Fifth Disease typically last?
How does Varicella often begin before the rash appears?
How does Varicella often begin before the rash appears?
Which group is primarily affected by Fifth Disease?
Which group is primarily affected by Fifth Disease?
What precaution is important for individuals with compromised hematopoietic function when infected with parvovirus B19?
What precaution is important for individuals with compromised hematopoietic function when infected with parvovirus B19?
What is a common treatment for managing high fevers in roseola?
What is a common treatment for managing high fevers in roseola?
What is the recommended strategy for treating nits after the initial treatment?
What is the recommended strategy for treating nits after the initial treatment?
Which area is most commonly involved in atopic dermatitis in older children?
Which area is most commonly involved in atopic dermatitis in older children?
What is a common finding associated with chronic rubbing in periocular areas due to atopic dermatitis?
What is a common finding associated with chronic rubbing in periocular areas due to atopic dermatitis?
Which treatment is often avoided for periocular atopic dermatitis due to potential side effects?
Which treatment is often avoided for periocular atopic dermatitis due to potential side effects?
What characteristic change is observed in the rash of atopic dermatitis as children age?
What characteristic change is observed in the rash of atopic dermatitis as children age?
What is keratosis pilaris, as described in the context of atopic dermatitis?
What is keratosis pilaris, as described in the context of atopic dermatitis?
What are the remnants that remain attached to the hairshaft after treatment for lice?
What are the remnants that remain attached to the hairshaft after treatment for lice?
What is the typical appearance of atopic dermatitis lesions in older children?
What is the typical appearance of atopic dermatitis lesions in older children?
What is the typical presentation of Henoch-Schonlein Purpura (HSP)?
What is the typical presentation of Henoch-Schonlein Purpura (HSP)?
Which of the following treatments is used for pityriasis alba?
Which of the following treatments is used for pityriasis alba?
Which complication can occur in cases of severe gastrointestinal manifestations of HSP?
Which complication can occur in cases of severe gastrointestinal manifestations of HSP?
What is the main finding observed in most cases of Henoch-Schonlein Purpura?
What is the main finding observed in most cases of Henoch-Schonlein Purpura?
Which condition is most often treated with milder topical acids such as lactic acid?
Which condition is most often treated with milder topical acids such as lactic acid?
What is the general duration of symptoms for Henoch-Schonlein Purpura?
What is the general duration of symptoms for Henoch-Schonlein Purpura?
Which of the following statements about Henoch-Schonlein Purpura is correct?
Which of the following statements about Henoch-Schonlein Purpura is correct?
What long-term monitoring is recommended for patients after resolution of Henoch-Schonlein Purpura?
What long-term monitoring is recommended for patients after resolution of Henoch-Schonlein Purpura?
Flashcards
Tinea corporis
Tinea corporis
A fungal infection of the skin that typically presents as a red, scaly ring with central clearing.
Trichophyton rubrum
Trichophyton rubrum
The most common causative organism of tinea corporis.
Tinea capitis
Tinea capitis
A fungal infection of the scalp that presents as areas of hair loss with scaling and possible erythema.
Trichophyton tonsurans
Trichophyton tonsurans
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Dermatophyte
Dermatophyte
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Scaling
Scaling
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KOH preparation
KOH preparation
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Fungal culture
Fungal culture
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Periungual Warts
Periungual Warts
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Warts
Warts
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Characteristics of Warts
Characteristics of Warts
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E6 and E7 (Early 5, 6, and 7) protein.
E6 and E7 (Early 5, 6, and 7) protein.
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L1 and L2 (Late 1 and 2) proteins.
L1 and L2 (Late 1 and 2) proteins.
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Periungual Wart
Periungual Wart
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Plantar Warts
Plantar Warts
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Flat Warts (also called 'Plane Warts')
Flat Warts (also called 'Plane Warts')
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Atopic Dermatitis (Eczema)
Atopic Dermatitis (Eczema)
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Keratosis Pilaris
Keratosis Pilaris
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Morgan-Dennie Lines
Morgan-Dennie Lines
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Pityriasis Alba
Pityriasis Alba
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Topical Permethrin
Topical Permethrin
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No Nit Policies
No Nit Policies
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Topical Malathion
Topical Malathion
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What is Keratosis Pilaris?
What is Keratosis Pilaris?
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What is Pityriasis Alba?
What is Pityriasis Alba?
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What is Henoch-Schonlein Purpura (HSP)?
What is Henoch-Schonlein Purpura (HSP)?
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What is Palpable Purpura?
What is Palpable Purpura?
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What is Chronic Renal Failure in HSP?
What is Chronic Renal Failure in HSP?
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What is Treatment for HSP?
What is Treatment for HSP?
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How does HSP affect different organs?
How does HSP affect different organs?
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What are the causes of HSP?
What are the causes of HSP?
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Roseola
Roseola
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Fifth Disease (Erythema Infectiosum)
Fifth Disease (Erythema Infectiosum)
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Varicella (Chickenpox)
Varicella (Chickenpox)
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Lymphotrophic Viruses
Lymphotrophic Viruses
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Latent Viruses
Latent Viruses
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Immune Response to Parvovirus B19 (Fifth Disease)
Immune Response to Parvovirus B19 (Fifth Disease)
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Fifth Disease vs. Lupus
Fifth Disease vs. Lupus
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Erythroid Progenitor Cell Tropism
Erythroid Progenitor Cell Tropism
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Varicella zoster virus (VZV)
Varicella zoster virus (VZV)
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Incubation period for varicella
Incubation period for varicella
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Viremia
Viremia
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Scalp pruritus (itching)
Scalp pruritus (itching)
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Head-to-head contact
Head-to-head contact
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Fomites
Fomites
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Study Notes
Tinea Capitis and Tinea Corporis
- Tinea corporis (ringworm of the body) is common in all races, and presents as a red, scaly ring with central clearing, sometimes with hyper/hypopigmentation in darker skin tones. It is not typically itchy or painful.
- Tinea capitis (ringworm of the scalp) is relatively common in African-American and Hispanic children, and is more common than in adults. It typically involves hair loss with scaling on the scalp, and may have some erythema and pustules. Some cases can be itchy or painful.
- Causative organisms:
- Tinea corporis: Trichophyton rubrum, Microsporum canis, and Trichophyton mentagrophytes.
- Tinea capitis: Trichophyton tonsurans.
- Both conditions are caused by dermatophytes, fungi that digest keratin, affecting stratum corneum, hair, and/or nails.
- Infections can be anthropophilic (human reservoir), zoophilic (animal reservoir), or geophilic (soil reservoir).
- The scaling of the rash is a defense mechanism. Stratum corneum sheds faster than the organism can proliferate, removing the infection from the skin. The clearing in the center of the rash shows this removal.
- Diagnosis: Potassium hydroxide (KOH) preparations or fungal cultures.
- Treatment: Azoles (ketoconazole, miconazole, etc) inhibit fungal growth; allylamine (e.g., terbinafine) inhibits squalene epoxidase, which is an alternative treatment.
Molluscum Contagiosum
- Extremely common in children. More common in those with atopic dermatitis.
- Presents as small (1-3 mm), shiny, skin-colored papules with a central dimple. Lesions can appear anywhere on the body, and can grow large in immunocompromised individuals.
- Caused by a DNA virus (poxvirus).
- Transmitted through contact with skin lesions, or through shared objects.
- Usually resolves spontaneously, but treatment includes scraping, salicylic acid, liquid nitrogen, or imiquimod.
Warts
- Caused by human papillomaviruses (HPVs).
- Various types of HPV cause different types of warts (e.g., plantar, periungual, "flat").
- HPV proteins (L1, L2, E5, E6, E7) hijack cellular proliferation, inactivating normal regulatory proteins (p53 and retinoblastoma). This allows for excessive proliferation of keratinocytes.
- Diagnosis is generally visual.
- Treatments include salicylic acid and liquid nitrogen.
Periungual Warts
- Warts near fingernails are common in children.
- Characterized by a rough, "verrucous" surface with black dots (thrombosed capillaries) beneath.
- Treatment approaches are similar to warts in other locations.
Pyogenic Granuloma
- Red, moist nodules that often result from minor trauma.
- Characterized by excessive wound healing response.
- Typically treated with surgical removal and cauterization to prevent recurrence.
Hand-Foot-Mouth Disease (HFMD) and Herpangina
- Caused by picornaviruses (e.g., Coxsackievirus A16).
- HFMD presents with vesicles or pustules (often on hands and feet) and oral erosions (typically in mouth).
- Herpangina involves only oral erosions.
- Typically resolves spontaneously.
Viral Exanthems
- Viral rashes are common, typically non-specific, presenting as widespread erythematous papules/papules, and urticarial lesions, with fever and possible malaise (general unwell feelings).
- Often caused by enteroviruses.
- Diagnoses based on clinical presentation.
- Treatment consists of supportive care for symptomatic relief.
Papular Acrodermatitis of Childhood (Gianotti-Crosti)
- Symmetric, monomorphic pink papules (bumps).
- Typically on face, buttocks, and extensor surfaces of extremities.
- Often occurs in children during spring/summer.
- May be associated with viral infections.
- Typically resolves without treatment.
Roseola Infantum
- Characterized by a high fever for several days, followed by a non-specific rash of pink macules and papules.
- Caused by HHV6 and HHV7.
- Typically resolves spontaneously.
Unilateral Thoracic Exanthem (UTE)
- Non-specific rash localized to one axilla or flank, but often spreads to the opposite.
- Etiology is believed to be viral but not yet isolated.
- Self-limiting with resolution within 1-2 months.
Varicella (Chickenpox)
- Characterized by a widespread eruption of small vesicles on erythematous bases.
- Caused by varicella-zoster virus (VZV), transmitted via respiratory droplets.
- Usually resolves spontaneously.
Pediculosis Capitis (Head Lice)
- Infestation of parasites (lice) on the head, characterized by intense itching.
- Female lice lay eggs (nits) that attach to hair shafts.
- Diagnosed by visual inspection; may have mobile lice or nits.
- Treated with topical permethrin, Malathion, or oral ivermectin.
Henoch-Schönlein Purpura (HSP)
- A type of vasculitis characterized by palpable purpura (reddish/purple spots) on the legs and buttocks, often triggered by an upper respiratory infection.
- Symptoms can range from mild (mild skin rash and/or GI distress) to potentially serious (kidney involvement or GI distress such as bloody stools or abdominal pain).
- Treat with supportive care for mild cases. More serious cases, require potentially oral steroids.
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