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Questions and Answers
What type of bacteria is tigecycline active against?
What type of bacteria is tigecycline active against?
- Vancomycin-resistant enterococci (correct)
- Penicillin-susceptible streptococci
- Extended-Spectrum β-Lactamase–nonproducing gram-negative bacteria
- Methicillin-susceptible staphylococci
What is tigecycline indicated for?
What is tigecycline indicated for?
- Treatment of uncomplicated urinary tract infections
- Treatment of complicated skin and soft-tissue infections (correct)
- Treatment of hospital-acquired pneumonia
- Treatment of meningitis
What is the primary route of elimination of tigecycline?
What is the primary route of elimination of tigecycline?
- Hepatic metabolism
- Lymphatic excretion
- Biliary/fecal excretion (correct)
- Renal excretion
Why is tigecycline a poor option for bloodstream infections?
Why is tigecycline a poor option for bloodstream infections?
What is a boxed warning associated with tigecycline?
What is a boxed warning associated with tigecycline?
What is a potential adverse effect of tigecycline therapy?
What is a potential adverse effect of tigecycline therapy?
Which macrolide is effective against Haemophilus influenzae?
Which macrolide is effective against Haemophilus influenzae?
What is the property of Roxithromycin that makes it useful in treating infections caused by intracellular bacteria?
What is the property of Roxithromycin that makes it useful in treating infections caused by intracellular bacteria?
Which of the following organisms is NOT typically targeted by Erythromycin?
Which of the following organisms is NOT typically targeted by Erythromycin?
Which of the following macrolides is a long-acting acid stable derivative of Erythromycin?
Which of the following macrolides is a long-acting acid stable derivative of Erythromycin?
What is the effect of Malaria on red blood cells?
What is the effect of Malaria on red blood cells?
Telithromycin is effective against which type of organisms?
Telithromycin is effective against which type of organisms?
What is a risk factor for Pseudomonas aeruginosa infections?
What is a risk factor for Pseudomonas aeruginosa infections?
What is the purpose of combining aminoglycosides with a β-lactam antibiotic?
What is the purpose of combining aminoglycosides with a β-lactam antibiotic?
What is gentamicin effective in treating?
What is gentamicin effective in treating?
What is a type of infection that can be treated with tobramycin alone?
What is a type of infection that can be treated with tobramycin alone?
What is the purpose of adding aminoglycosides to β-lactams for select serious gram-positive infections?
What is the purpose of adding aminoglycosides to β-lactams for select serious gram-positive infections?
What is the mechanism of action of macrolide antibiotics?
What is the mechanism of action of macrolide antibiotics?
Which antibiotic is considered an alternative in patients with penicillin allergy?
Which antibiotic is considered an alternative in patients with penicillin allergy?
Which macrolide antibiotic exhibits greater activity against intracellular pathogens such as H. Pylori?
Which macrolide antibiotic exhibits greater activity against intracellular pathogens such as H. Pylori?
Which antibiotic is a safe option for a pregnant woman with community-acquired pneumonia?
Which antibiotic is a safe option for a pregnant woman with community-acquired pneumonia?
What is the difference in spectrum of activity between erythromycin and azithromycin?
What is the difference in spectrum of activity between erythromycin and azithromycin?
What is a characteristic of azithromycin compared to erythromycin?
What is a characteristic of azithromycin compared to erythromycin?
What is the mechanism of action of quinupristin/dalfopristin?
What is the mechanism of action of quinupristin/dalfopristin?
What is the primary indication for the use of quinupristin/dalfopristin?
What is the primary indication for the use of quinupristin/dalfopristin?
What is the consequence of enzymatic modification of quinupristin/dalfopristin in some cases?
What is the consequence of enzymatic modification of quinupristin/dalfopristin in some cases?
What adverse effects have been reported with the administration of higher doses of quinupristin/dalfopristin?
What adverse effects have been reported with the administration of higher doses of quinupristin/dalfopristin?
What is the mechanism by which quinupristin/dalfopristin induces hyperbilirubinemia?
What is the mechanism by which quinupristin/dalfopristin induces hyperbilirubinemia?
What is the consequence of bacterial efflux pumps on quinupristin/dalfopristin?
What is the consequence of bacterial efflux pumps on quinupristin/dalfopristin?
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