Podcast
Questions and Answers
Which bacterial resistance mechanisms does Tigecycline overcome in relation to tetracyclines?
Which bacterial resistance mechanisms does Tigecycline overcome in relation to tetracyclines?
- RNA transcription and gene expression
- Efflux pump acquisition and ribosomal protection (correct)
- Cell wall synthesis and DNA replication
- Membrane permeability and cell division
How does Tigecycline act on bacteria to inhibit protein synthesis?
How does Tigecycline act on bacteria to inhibit protein synthesis?
- By inhibiting DNA replication
- By disrupting cell wall synthesis
- By interfering with RNA transcription
- By binding to the 30S ribosomal subunit and blocking entry of Aminoacyl-tRNA (correct)
Which type of bacteria is Tigecycline effective against?
Which type of bacteria is Tigecycline effective against?
- Only Gram-negative bacteria
- Only Gram-positive bacteria
- Gram-positive, Gram-negative, and anaerobes (correct)
- Only Pseudomonas spp.
What is the primary reason for not prescribing tetracyclines to children under 8 years of age?
What is the primary reason for not prescribing tetracyclines to children under 8 years of age?
What class of antibiotics does Tigecycline belong to?
What class of antibiotics does Tigecycline belong to?
Which antibiotic acts by inhibiting protein synthesis through forming a stable complex with elongation factor EF-G?
Which antibiotic acts by inhibiting protein synthesis through forming a stable complex with elongation factor EF-G?
What is the mechanism of action of tetracyclines?
What is the mechanism of action of tetracyclines?
Which antibiotic has a broad spectrum that covers atypical bacteria such as Mycoplasma and Chlamydia?
Which antibiotic has a broad spectrum that covers atypical bacteria such as Mycoplasma and Chlamydia?
What is a common side effect associated with tetracyclines?
What is a common side effect associated with tetracyclines?
Which antibiotic is less susceptible to inactivating enzymes due to its chemical structure?
Which antibiotic is less susceptible to inactivating enzymes due to its chemical structure?
Which antibiotic is used topically only and is not active against Pseudomonas aeruginosa?
Which antibiotic is used topically only and is not active against Pseudomonas aeruginosa?
Which antibiotic is effective against MRSA?
Which antibiotic is effective against MRSA?
Why should patients receiving tetracyclines be kept out of heavy sunlight?
Why should patients receiving tetracyclines be kept out of heavy sunlight?
Which tetracycline is excreted primarily in the intestinal tract?
Which tetracycline is excreted primarily in the intestinal tract?
What is the main reason for the yellow discoloration of teeth associated with tetracycline use?
What is the main reason for the yellow discoloration of teeth associated with tetracycline use?
In what body fluids do tetracyclines reach high concentrations?
In what body fluids do tetracyclines reach high concentrations?
Which substance decreases the absorption of tetracyclines?
Which substance decreases the absorption of tetracyclines?
What impact do tetracyclines have on normal flora in the body?
What impact do tetracyclines have on normal flora in the body?
