Questions and Answers
What is the generic name of the medication?
ticagrelor
What is the trade name of ticagrelor?
Brilinta
What classification does ticagrelor belong to?
P2Y platelet aggregation inhibitor; Antiplatelet
What are the actions of ticagrelor?
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What is one indication for the use of ticagrelor?
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What is the typical dosage for ticagrelor?
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Which of the following is NOT a contraindication for ticagrelor?
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Precautions for ticagrelor include ______ hepatic impairment and risk factors for bleeding.
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What should be noted about the initial treatment with ticagrelor?
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When should ticagrelor be discontinued prior to surgery?
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Study Notes
Ticagrelor Overview
- Generic Name: Ticagrelor
- Trade Name: Brilinta
Classification
- Type: P2Y platelet aggregation inhibitor
- Category: Antiplatelet medication
Pharmacodynamics
- Mechanism: Reduces platelet aggregation by reversibly inhibiting the P2Y12 ADP receptor.
- Purpose: Prevents signal transduction and platelet activation.
Clinical Indications
- Used to reduce thrombolytic cardiovascular events alongside aspirin in patients with acute coronary syndrome.
Dosage Information
- Route: Oral administration
- Standard Dose: 180 mg single dose, typically given with 325 mg of aspirin.
- Note: Dosage is determined based on VHR physician/protocol directives.
Contraindications
- Not for use in patients with:
- History of hypersensitivity to the drug
- Previous intracranial hemorrhage
- Active pathological bleeding
- Severe hepatic impairment
Precautions
- Use with caution in patients with:
- Moderate hepatic impairment
- Renal impairment
- Elevated risk factors for bleeding
Additional Notes
- Can be the initial treatment if a patient has an allergy to aspirin or significant gastrointestinal intolerance to aspirin.
- Should not be started in patients scheduled for coronary artery bypass graft surgery.
- Discontinue ticagrelor 5 days before any surgical procedures.
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Description
This quiz consists of flashcards focused on ticagrelor, including its generic and trade names, classification, and pharmacodynamic actions. Test your knowledge on the specifics of this important antiplatelet medication and its role in reducing platelet aggregation.
