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Questions and Answers
What is the primary function of the thyroid hormone?
What is the primary function of the thyroid hormone?
Regulation of metabolic rate
What is the mechanism of action of thyroid drugs such as levothyroxine?
What is the mechanism of action of thyroid drugs such as levothyroxine?
Replacement of endogenous thyroid hormone
What is the main use of antithyroid drugs such as methimazole?
What is the main use of antithyroid drugs such as methimazole?
Treatment of hyperthyroidism
What is the effect of thyroid hormones on the heart rate?
What is the effect of thyroid hormones on the heart rate?
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What is the potential side effect of long-term use of thyroid hormone replacement therapy?
What is the potential side effect of long-term use of thyroid hormone replacement therapy?
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Study Notes
Thyroid Hormones
- Thyroid hormones are produced by the thyroid gland and play a crucial role in regulating metabolism, growth, and development.
- The two main thyroid hormones are triiodothyronine (T3) and thyroxine (T4).
Functions of Thyroid Hormones
- Regulate metabolic rate and energy expenditure
- Influence growth and development, particularly in children and adolescents
- Play a role in the regulation of body temperature
Hypothyroidism
- A condition characterized by underactive thyroid gland, resulting in insufficient production of thyroid hormones
- Symptoms include fatigue, weight gain, dry skin, and hair loss
- Treatment involves replacement therapy with synthetic thyroid hormones (e.g., levothyroxine)
Hyperthyroidism
- A condition characterized by overactive thyroid gland, resulting in excessive production of thyroid hormones
- Symptoms include weight loss, anxiety, heat intolerance, and rapid heartbeat
- Treatment involves reducing thyroid hormone production using antithyroid drugs or radioactive iodine therapy
Antithyroid Drugs
- Medications used to treat hyperthyroidism by reducing thyroid hormone production
- Examples of antithyroid drugs include methimazole and propylthiouracil
- These drugs work by inhibiting the production of thyroid hormones or blocking their release from the thyroid gland
Action of Antithyroid Drugs
- Methimazole: inhibits the enzyme thyroid peroxidase, reducing thyroid hormone synthesis
- Propylthiouracil: inhibits the enzyme thyroid peroxidase and also blocks the peripheral conversion of T4 to T3
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Description
This quiz covers the basics of thyroid hormones, their functions, and related disorders. Learn about the roles of T3 and T4, and the effects of hypothyroidism.