Thyroid Hormone Synthesis and Regulation

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Questions and Answers

What is the primary function of peroxidase enzymes in the synthesis of thyroid hormones?

  • To produce thyroxine-binding globulins
  • To regulate the release of thyroid hormones into the bloodstream
  • To cleave T3 and T4 from thyroglobulin
  • To mediate the attachment of iodine to tyrosine (correct)

What is the result of inadequate iodine intake on the thyroid gland?

  • The thyroid gland atrophies
  • The thyroid gland enlarges and protrudes (correct)
  • The thyroid gland produces excessive amounts of T3 and T4
  • The thyroid gland stops producing thyroid hormones

What is the primary cause of cretinism or congenital hypothyroidism?

  • Hyperthyroidism during infancy
  • Thyroid gland atrophy
  • Genetic deficiency or maternal factors (correct)
  • Iodine deficiency during pregnancy

What is the primary symptom of exophthalmos in Grave's disease?

<p>Protrusion of the eyeballs (B)</p> Signup and view all the answers

What is the primary mechanism of negative feedback in regulating thyroid hormone levels?

<p>Thyroid hormones inhibit the production of TRH (C)</p> Signup and view all the answers

What is the primary treatment for myxedema?

<p>Iodine supplements or hormone replacement therapy (A)</p> Signup and view all the answers

What is the primary cause of hyperthyroidism in Grave's disease?

<p>Production of antibodies that mimic TSH (D)</p> Signup and view all the answers

What is the primary function of thyroxine-binding globulins (TBGs)?

<p>Bind to T3 and T4, regulating their levels (B)</p> Signup and view all the answers

What is the primary role of testosterone in the male reproductive system?

<p>Maturation of male reproductive organs and development of secondary sexual characteristics (B)</p> Signup and view all the answers

Which hormone produced by the heart reduces blood pressure, blood volume, and blood sodium concentration?

<p>Atrial natriuretic peptide (ANP) (A)</p> Signup and view all the answers

What is the primary function of enteroendocrine cells in the gastrointestinal tract?

<p>Release of local-acting digestive hormones (A)</p> Signup and view all the answers

Which structure produces human chorionic gonadotropin (hCG) during pregnancy?

<p>Placenta (B)</p> Signup and view all the answers

What is the primary role of leptin in the body?

<p>Involved in the sensation of satiety and stimulation of increased energy expenditure (A)</p> Signup and view all the answers

Which hormone-producing glands arise from the mesoderm?

<p>Those that produce steroid hormones (C)</p> Signup and view all the answers

What is the primary function of cholecalciferol in the body?

<p>Precursor of vitamin D (D)</p> Signup and view all the answers

Which hormone-producing structure is responsible for the development of secondary sexual characteristics in females?

<p>Ovaries (A)</p> Signup and view all the answers

Which part of the adrenal gland secretes epinephrine in response to sympathetic stimulation?

<p>Adrenal medulla (C)</p> Signup and view all the answers

What is necessary for the synthesis of aldosterone?

<p>Aldosterone synthase (B)</p> Signup and view all the answers

What hormone does the middle layer of the adrenal cortex secrete?

<p>Cortisol (D)</p> Signup and view all the answers

Which hormones are secreted by the adrenal medulla?

<p>Epinephrine and norepinephrine (C)</p> Signup and view all the answers

From what are corticosteroids synthesized?

<p>Cholesterol (C)</p> Signup and view all the answers

Which part of the adrenal gland is related to the sympathetic nervous system?

<p>Adrenal medulla (D)</p> Signup and view all the answers

What does the deep layer of the adrenal cortex secrete?

<p>Adrenal androgens and small amounts of estrogens and glucocorticoids (B)</p> Signup and view all the answers

What can be a result of a parathyroid gland tumor?

<p>All of the above (D)</p> Signup and view all the answers

Which symptom is not typically associated with hypersecretion of the sympathetic nervous system?

<p>Bradycardia (D)</p> Signup and view all the answers

Which statement best describes the function of glucagon secreted by the pancreas?

<p>Increases blood glucose levels (A)</p> Signup and view all the answers

What is the primary function of melatonin in the human body?

<p>Regulates day/night cycles (A)</p> Signup and view all the answers

Which cells in the pancreatic islets are responsible for insulin secretion?

<p>Beta cells (C)</p> Signup and view all the answers

Which of the following describes the pineal gland's location?

<p>In the roof of the third ventricle (A)</p> Signup and view all the answers

Which function is directly influenced by melatonin?

<p>Resetting biological clock (B)</p> Signup and view all the answers

What is the primary role of the acinar cells in the pancreas?

<p>Production of digestive juices (A)</p> Signup and view all the answers

Which process is NOT stimulated by the hormone glucagon?

<p>Reduction of blood glucose levels (C)</p> Signup and view all the answers

What is one of the primary actions of calcitonin on the skeleton?

<p>Inhibits osteoclast activity (B)</p> Signup and view all the answers

Which cells are responsible for the synthesis and secretion of calcitonin?

<p>Parafollicular cells (B)</p> Signup and view all the answers

How does PTH increase calcium levels in the blood?

<p>By increasing the absorption of calcium by intestinal mucosal cells (D)</p> Signup and view all the answers

Which statement describes the primary regulation mechanism for calcitonin secretion?

<p>A negative feedback mechanism based on blood calcium levels (A)</p> Signup and view all the answers

What are the symptoms associated with hypoparathyroidism?

<p>Prolonged muscle spasms (B)</p> Signup and view all the answers

Which gland is responsible for the secretion of PTH?

<p>Parathyroid gland (D)</p> Signup and view all the answers

What is a common effect of hyperparathyroidism?

<p>Weak skeletal muscles (B)</p> Signup and view all the answers

Which of the following actions does PTH not perform?

<p>Inhibits osteoclast activity (D)</p> Signup and view all the answers

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