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Thyroid Hormones and Biosynthesis
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Thyroid Hormones and Biosynthesis

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Questions and Answers

What is the function of the enzyme 'iodothyronine deiodinase' in the synthesis of thyroid hormones?

  • It catalyzes the reductive process of deiodination to convert T4 to T3 (correct)
  • It catalyzes the formation of iodothyronines from iodotyrosines
  • It catalyzes the proteolysis of thyroglobulin and release of T4 and T3
  • It catalyzes the oxidation of iodide and formation of iodotyrosyine residues
  • What are the two major thyroid hormones formed by the coupling of two DIT or one DIT with one MIT residue?

  • T3 and rT3
  • rT3 and T4
  • MIT and DIT
  • T4 and T3 (correct)
  • What is the function of thyroglobulin proteolysis?

  • It converts T4 to T3
  • It releases T4 and T3 into the blood (correct)
  • It catalyzes the oxidation of iodide and formation of iodotyrosyine residues
  • It forms iodothyronines from iodotyrosines
  • What is the name of the prodrug derivative of methimazole?

    <p>Carbimazole</p> Signup and view all the answers

    What are the two rings in the nomenclature of thyroid hormones?

    <p>Inner ring and outer ring</p> Signup and view all the answers

    What is the function of antithyroid drugs?

    <p>To treat hyperthyroidism</p> Signup and view all the answers

    What is the origin of prostaglandins?

    <p>Mammalian tissue</p> Signup and view all the answers

    What is the first step in the biosynthesis of thyroid hormones?

    <p>Accumulative uptake of iodide by the follicular cell</p> Signup and view all the answers

    What is the full name of L-Thyroxine (T4)?

    <p>L-(-)-3,5,3’,5’-tetraiodo-L-thyronine</p> Signup and view all the answers

    What is the function of iodide in the treatment of hyperthyroidism?

    <p>It is used as an antithyroid drug</p> Signup and view all the answers

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