Thyroid Hormone Synthesis and Function

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17 Questions

What is the primary source of iodine for thyroid hormone synthesis?

Diet

Which of the following thyroid hormones has a longer half-life?

T4

What is the primary function of T4 in thyroid hormone physiology?

Acting as a precursor to T3

What is the structure of the thyroid gland in which thyroglobulin is stored?

Follicular structure

What hormone stimulates the thyroid gland to release thyroid hormones?

Thyroid stimulating hormone (TSH)

What is the effect of hyperthyroidism on the cardiovascular system?

Increased force of contraction

What is the primary cause of hypothyroidism in iodine deficiency?

Inability to synthesize T3 and T4

What is the effect of thyroid-stimulating immunoglobulin (LATS) on thyroid follicular cells?

Over-stimulation of T4/T3 synthesis and secretion

What is the result of high TSH levels in iodine deficiency?

Gland enlargement

What is the effect of hypothyroidism on the central nervous system?

Mental sluggishness

What is the characteristic of thyroid gland morphology in hypothyroidism due to iodine deficiency?

Gland enlargement

What is the effect of thyroid hormone on the cardiovascular system?

Increased manufacture and incorporation of β1 adrenergic receptors

What is the role of TRH in the regulation of thyroid hormone secretion?

TRH stimulates the release of TSH

What is the effect of TSH on the thyroid gland?

TSH increases the size and secretory activity of thyroid cells

What happens to thyroid gland morphology when TSH levels are high?

Follicles become depleted, and the epithelium becomes columnar

What is the role of thyroid hormone in childhood development?

Thyroid hormone is critical for central nervous system development

What is the effect of high levels of thyroid hormone on the regulation of TSH and TRH?

High T3/T4 levels suppress the release of TRH and TSH

This quiz covers the basics of thyroid hormones, including their synthesis, structure, and function. Learn about the role of iodine, thyroglobuline, and the differences between T3 and T4.

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