6 Questions
What is the role of calcitonin produced by parafollicular cells in the thyroid gland?
Regulating calcium homeostasis
Which cells are primarily responsible for the production and secretion of thyroid hormones T3 and T4?
Follicular cells
Where are parafollicular cells predominantly located in the thyroid gland?
Upper part
Which artery supplies blood to the thyroid gland directly from the thyrocervical trunk?
Inferior thyroid artery
What is the main function of follicular cells in the thyroid gland?
Production of T3 and T4 hormones
Which structure connects the two lateral lobes of the thyroid gland?
Isthmus
Study Notes
Thyroid Gland Anatomy
The thyroid gland is a butterfly-shaped endocrine gland located in the anterior neck, surrounded by the hyoid bone and the trachea. It consists of two lateral lobes connected by a central mass called the isthmus, which comes into continuity with the thyroglossal duct remnants. The thyroid gland plays a crucial role in regulating metabolism through its synthesis of three hormones: triiodothyronine (T3), tetraiodothyronine (T4), and calcitonin.
Structure
Follicular Cells
Follicular cells constitute about 95% of the total cell population of the thyroid gland. They are responsible for the production and secretion of T3 and T4 hormones, also known as thyroid hormones. These hormones play essential roles in maintaining basal metabolic rate, growth development, body temperature, heart function, etc..
Parafollicular Cells
Parafollicular cells, also known as parathyroidoid-producing cells or C cells, represent less than 5% of the total cell population and are more abundant in the upper part of the thyroid gland. These cells produce and secrete calcitonin, a peptide hormone involved in calcium homeostasis and regulation of insulin and glucagon levels.
Blood Supply
The thyroid gland receives blood from both sides via the superior thyroid artery and the inferior thyroid artery. The superior thyroid artery branches off the external carotid artery, while the inferior thyroid artery originates directly from the thyrocervical trunk. Both these blood vessels supply oxygen and nutrients to the thyroid gland, facilitating the various cellular processes within it.
In summary, the thyroid gland is a complex organ composed of follicular and parafollicular cells, each playing unique roles in the production of thyroid and calcitonin hormones. Its structure allows for efficient blood flow to support these vital functions, making it an integral component of human physiology.
Explore the structure of the thyroid gland, including the roles of follicular and parafollicular cells in hormone production. Learn about the blood supply to the thyroid gland and its crucial functions in regulating metabolism and calcium levels.
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