Thyroid Function and Drug Interactions Quiz

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Which drug for hypothyroidism generally has a faster onset but a shorter duration of action compared to the other?

Levothyroxine

Synthetic T3 with an unknown name

A new thyroid hormone not mentioned in the text

Liothyronine (correct)

What can happen if a patient experiences chronic overdose of thyroid hormones?

Hyperthyroidism (correct)

Hypothyroidism

Improved eye inflammation

Increased thyroid hormone synthesis

Which situation is liothyronine (T3) generally reserved for?

Preventing osteoporosis

Chronic hypothyroidism treatment

Myxedema coma (correct)

Thyroid hormone synthesis

What could occur if patients undergo less severe overdose of thyroid hormones?

Adverse effects despite overall well-being Signup and view all the answers

What potential health risk can chronic overdose of thyroid hormones pose to patients?

Osteoporosis Signup and view all the answers

What characteristic makes liothyronine (T3) more potent than levothyroxine (T4)?

Shorter duration of action Signup and view all the answers

What can occur if patients ingest certain foods such as cassava root or anions mimicking iodine?

Hyperthyroidism Signup and view all the answers

In what cases are certain drugs for hypothyroidism like liothyronine (T3) generally used?

For quick symptom relief in thyroid emergencies Signup and view all the answers

What adverse effect can be particularly deceptive in cases of less severe overdose of thyroid hormones?

Adverse effects while feeling well overall Signup and view all the answers

What is the main role of certain foods and anions like cassava root and thiocyanate concerning the thyroid gland?

Blocking iodine uptake Signup and view all the answers

Which type of beta-blockers are often preferred due to their cardio-selectivity without intrinsic sympathomimetic activity (ISA)?

Metoprolol Signup and view all the answers

Which of the following beta-blockers with intrinsic sympathomimetic activity (ISA) are contraindicated in hyperthyroidism?

Acebutolol Signup and view all the answers

Which medication is used for thyroid eye disease (TED) due to its ability to suppress autoimmune inflammation and swelling of the eye?

Guanethidine eye drops Signup and view all the answers

What is the function of Teprotumumab in the management of thyroid eye disease (TED)?

Blocking IGF-1R to prevent autoimmune activation Signup and view all the answers

Which drug is NOT useful for the management of TED due to the absence of β-adrenergic receptors in orbital muscles?

Betaxolol Signup and view all the answers

Why are anti-thyroid drugs considered useless in the treatment of TED?

Because of their inability to target thyroid hormone receptors in orbital muscles Signup and view all the answers

Which hormone receptor forms complexes with TSH receptor-like proteins in the eye in the pathophysiology of TED?

IGF-1R Signup and view all the answers

Which medication primarily works by suppressing the autoimmune inflammation and swelling of the eye in TED?

Prednisolone Signup and view all the answers

What is the significant role of guanethidine in the management of TED?

Blocking noradrenergic receptors Signup and view all the answers

Why are beta-blockers not useful in TED despite their pharmacological action as beta-adrenergic receptor antagonists?

There are no adrenergic receptors in orbital muscles Signup and view all the answers