Thyroid Function and Drug Interactions Quiz
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Questions and Answers

Which drug for hypothyroidism generally has a faster onset but a shorter duration of action compared to the other?

  • Levothyroxine
  • Synthetic T3 with an unknown name
  • A new thyroid hormone not mentioned in the text
  • Liothyronine (correct)
  • What can happen if a patient experiences chronic overdose of thyroid hormones?

  • Hyperthyroidism (correct)
  • Hypothyroidism
  • Improved eye inflammation
  • Increased thyroid hormone synthesis
  • Which situation is liothyronine (T3) generally reserved for?

  • Preventing osteoporosis
  • Chronic hypothyroidism treatment
  • Myxedema coma (correct)
  • Thyroid hormone synthesis
  • What could occur if patients undergo less severe overdose of thyroid hormones?

    <p>Adverse effects despite overall well-being</p> Signup and view all the answers

    What potential health risk can chronic overdose of thyroid hormones pose to patients?

    <p>Osteoporosis</p> Signup and view all the answers

    What characteristic makes liothyronine (T3) more potent than levothyroxine (T4)?

    <p>Shorter duration of action</p> Signup and view all the answers

    What can occur if patients ingest certain foods such as cassava root or anions mimicking iodine?

    <p>Hyperthyroidism</p> Signup and view all the answers

    In what cases are certain drugs for hypothyroidism like liothyronine (T3) generally used?

    <p>For quick symptom relief in thyroid emergencies</p> Signup and view all the answers

    What adverse effect can be particularly deceptive in cases of less severe overdose of thyroid hormones?

    <p>Adverse effects while feeling well overall</p> Signup and view all the answers

    What is the main role of certain foods and anions like cassava root and thiocyanate concerning the thyroid gland?

    <p>Blocking iodine uptake</p> Signup and view all the answers

    Which type of beta-blockers are often preferred due to their cardio-selectivity without intrinsic sympathomimetic activity (ISA)?

    <p>Metoprolol</p> Signup and view all the answers

    Which of the following beta-blockers with intrinsic sympathomimetic activity (ISA) are contraindicated in hyperthyroidism?

    <p>Acebutolol</p> Signup and view all the answers

    Which medication is used for thyroid eye disease (TED) due to its ability to suppress autoimmune inflammation and swelling of the eye?

    <p>Guanethidine eye drops</p> Signup and view all the answers

    What is the function of Teprotumumab in the management of thyroid eye disease (TED)?

    <p>Blocking IGF-1R to prevent autoimmune activation</p> Signup and view all the answers

    Which drug is NOT useful for the management of TED due to the absence of β-adrenergic receptors in orbital muscles?

    <p>Betaxolol</p> Signup and view all the answers

    Why are anti-thyroid drugs considered useless in the treatment of TED?

    <p>Because of their inability to target thyroid hormone receptors in orbital muscles</p> Signup and view all the answers

    Which hormone receptor forms complexes with TSH receptor-like proteins in the eye in the pathophysiology of TED?

    <p>IGF-1R</p> Signup and view all the answers

    Which medication primarily works by suppressing the autoimmune inflammation and swelling of the eye in TED?

    <p>Prednisolone</p> Signup and view all the answers

    What is the significant role of guanethidine in the management of TED?

    <p>Blocking noradrenergic receptors</p> Signup and view all the answers

    Why are beta-blockers not useful in TED despite their pharmacological action as beta-adrenergic receptor antagonists?

    <p>There are no adrenergic receptors in orbital muscles</p> Signup and view all the answers

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