Thyroid Function and Drug Interactions Quiz

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Questions and Answers

Which drug for hypothyroidism generally has a faster onset but a shorter duration of action compared to the other?

  • Levothyroxine
  • Synthetic T3 with an unknown name
  • A new thyroid hormone not mentioned in the text
  • Liothyronine (correct)

What can happen if a patient experiences chronic overdose of thyroid hormones?

  • Hyperthyroidism (correct)
  • Hypothyroidism
  • Improved eye inflammation
  • Increased thyroid hormone synthesis

Which situation is liothyronine (T3) generally reserved for?

  • Preventing osteoporosis
  • Chronic hypothyroidism treatment
  • Myxedema coma (correct)
  • Thyroid hormone synthesis

What could occur if patients undergo less severe overdose of thyroid hormones?

<p>Adverse effects despite overall well-being (C)</p> Signup and view all the answers

What potential health risk can chronic overdose of thyroid hormones pose to patients?

<p>Osteoporosis (B)</p> Signup and view all the answers

What characteristic makes liothyronine (T3) more potent than levothyroxine (T4)?

<p>Shorter duration of action (D)</p> Signup and view all the answers

What can occur if patients ingest certain foods such as cassava root or anions mimicking iodine?

<p>Hyperthyroidism (A)</p> Signup and view all the answers

In what cases are certain drugs for hypothyroidism like liothyronine (T3) generally used?

<p>For quick symptom relief in thyroid emergencies (D)</p> Signup and view all the answers

What adverse effect can be particularly deceptive in cases of less severe overdose of thyroid hormones?

<p>Adverse effects while feeling well overall (A)</p> Signup and view all the answers

What is the main role of certain foods and anions like cassava root and thiocyanate concerning the thyroid gland?

<p>Blocking iodine uptake (D)</p> Signup and view all the answers

Which type of beta-blockers are often preferred due to their cardio-selectivity without intrinsic sympathomimetic activity (ISA)?

<p>Metoprolol (A)</p> Signup and view all the answers

Which of the following beta-blockers with intrinsic sympathomimetic activity (ISA) are contraindicated in hyperthyroidism?

<p>Acebutolol (A)</p> Signup and view all the answers

Which medication is used for thyroid eye disease (TED) due to its ability to suppress autoimmune inflammation and swelling of the eye?

<p>Guanethidine eye drops (D)</p> Signup and view all the answers

What is the function of Teprotumumab in the management of thyroid eye disease (TED)?

<p>Blocking IGF-1R to prevent autoimmune activation (A)</p> Signup and view all the answers

Which drug is NOT useful for the management of TED due to the absence of β-adrenergic receptors in orbital muscles?

<p>Betaxolol (B)</p> Signup and view all the answers

Why are anti-thyroid drugs considered useless in the treatment of TED?

<p>Because of their inability to target thyroid hormone receptors in orbital muscles (C)</p> Signup and view all the answers

Which hormone receptor forms complexes with TSH receptor-like proteins in the eye in the pathophysiology of TED?

<p>IGF-1R (D)</p> Signup and view all the answers

Which medication primarily works by suppressing the autoimmune inflammation and swelling of the eye in TED?

<p>Prednisolone (B)</p> Signup and view all the answers

What is the significant role of guanethidine in the management of TED?

<p>Blocking noradrenergic receptors (C)</p> Signup and view all the answers

Why are beta-blockers not useful in TED despite their pharmacological action as beta-adrenergic receptor antagonists?

<p>There are no adrenergic receptors in orbital muscles (A)</p> Signup and view all the answers

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