10 Questions
What is the initial step in the synthesis of thyroid hormones?
Trapping of iodide
Which enzyme is responsible for the oxidation of iodide to iodine in the synthesis of thyroid hormones?
Peroxidase enzyme
What is the active form of iodine that combines with tyrosine in the colloid during thyroid hormone synthesis?
DIT
Where do the synthesized thyroid hormones diffuse into after being cleaved from thyroglobulin colloid?
Bloodstream
What is the function of lysosomal enzymes in the synthesis of thyroid hormones?
Cleaving T3 and T4 from thyroglobulin colloid
Which enzyme is responsible for de-iodinating the iodine released from uncoupled mono and di-iodotyrosine in the thyroid?
Dehalogenase
What is the main fraction of T3 and T4 bound to in the blood?
Plasma proteins
What class of antithyroid drugs inhibits the peripheral conversion of T4 to T3?
Thioamide
Which researchers proposed the 'Wolff-Chaikoff effect' related to the alteration of thyroid hormone levels by large doses of iodine?
Dr. Jan Wolff and Israel Lyon Chaikoff
What is considered as the most useful biochemical test in thyroid investigations according to the provided text?
Serum TSH level
Learn about different common thyroid diseases, their etiology, clinical manifestations, diagnosis, and management strategies through this quiz. Test your knowledge with multiple-choice and multiple-extended questions.
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