Thyroid Cancer Research Grant

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Questions and Answers

Which organization is supporting ThyCa: Thyroid Cancer Survivors’ Association, Inc?

ThyCa: Thyroid Cancer Survivors’ Association, Inc.

Both ATA and ThyCa: Thyroid Cancer Survivors’ Association, Inc. (correct)

American Thyroid Association (ATA)

Massachusetts General Hospital

What is the name of the grant awarded to Viswanath Gunda, Ph.D?

Combining Immune Checkpoints Inhibitors Grant

ThyCa Research Grant

2016 Thyroid Cancer Research Grant

ATA Research Grant (correct)

What is the focus of Dr. Gunda's research project?

Comparing the effectiveness of different thyroid cancer treatments

Developing a new treatment for thyroid cancer

Studying the role of oncogene mutations in thyroid cancer

Understanding the role of immune checkpoint receptors in thyroid cancer (correct)

What is the purpose of the inhibitors of immune checkpoint receptors in Dr. Gunda's research?

To block the checkpoint receptors and allow for immune system recognition of tumor cells Signup and view all the answers

What is the role of checkpoint receptors in thyroid cancer?

They prevent the immune system from recognizing and destroying cancer cells Signup and view all the answers

What is the name of the chair of the ATA Research Committee?

Dr. Motoyasu Saji Signup and view all the answers

How many grant applications does the ATA receive every year?

Over 50 Signup and view all the answers

What kind of mouse model is used in Dr. Gunda's research?

Immunocompetent mouse model Signup and view all the answers

How many thyroid research grants has the American Thyroid Association (ATA) awarded since the inception of the Research Fund?

85 Signup and view all the answers

What is the total amount of money donated to the ATA for research grants from ThyCa and Bite Me Cancer?

$1.8 million Signup and view all the answers

What is the primary focus of the research grants funded by ThyCa?

Thyroid cancer and medullary thyroid cancer Signup and view all the answers

How many research grants has Bite Me Cancer funded since 2014?

5 Signup and view all the answers

What is the purpose of the American Thyroid Association (ATA)?

To advance the understanding, prevention, diagnosis, and treatment of thyroid disorders and thyroid cancer Signup and view all the answers

How many clinicians and researchers are members of the American Thyroid Association (ATA)?

1,700 Signup and view all the answers

What is the total amount of money awarded by the ATA for research grants since the inception of the Research Fund?

$2.2 million Signup and view all the answers

What is the role of the American Thyroid Association (ATA) in the research grant program?

The ATA rigorously manages the selection of research projects and distribution of funds Signup and view all the answers

Study Notes

Thyroid Cancer Research Grant

The American Thyroid Association (ATA) awarded a 2016 ThyCa Research Grant to Dr. Viswanath Gunda for his project "Combining Immune Checkpoints Inhibitors with BRAF Targeted Therapy in Thyroid Cancer."
Dr. Gunda is an Instructor in Surgery at Massachusetts General Hospital, Boston, MA.

Project Overview

The project explores combinatorial approaches to treating thyroid cancer, targeting oncogene mutations (BRAFV600E) and kinase pathways (VEGFR) with an immunotherapeutic component.
The goal is to stimulate the body's natural defenses to recognize and kill tumor cells.

Immune Checkpoint Receptors

Checkpoint receptors (PD-1/PD-L1) are proteins on T-cells that prevent them from destroying cancer cells.
Tumors exploit these checkpoints to evade the immune system and escape detection.

Research Focus

Dr. Gunda's proposal focuses on understanding the role of PD-1/PD-L1 in thyroid cancer and studying the potential for inhibitors to have synergistic effects when combined with MAPKinase inhibitors and multi-kinase VEGFR inhibitors.
He will study the effectiveness of anti-PD-1 and anti-PD-L1 antibodies in blocking checkpoint receptors and allowing for immune system recognition and elimination of tumor cells in an immunocompetent mouse model of anaplastic thyroid cancer.

ATA Research Committee

The ATA Research Committee, chaired by Dr. Motoyasu Saji, has been supporting young scientists in various thyroid-related research areas, including clinical, translational, and basic areas.
The committee receives over 50 grant applications from various countries every year.

Funding and Support

The ATA has awarded 85 thyroid research grants totaling over $2.2 million since the inception of the Research Fund.
ThyCa: Thyroid Cancer Survivors' Association, Inc. has provided funding in support of 60 special research grants totaling $1,680,000 focused on thyroid cancer and medullary thyroid cancer since 2003.
Bite Me Cancer has supported five thyroid cancer grants since 2014, totaling $143,750.
The ATA supports all administrative and financial oversight for the research grant program.

Organizations

The American Thyroid Association (ATA) is the leading worldwide organization dedicated to the advancement, understanding, prevention, diagnosis, and treatment of thyroid disorders and thyroid cancer.
ThyCa: Thyroid Cancer Survivors' Association, Inc. is a member of the ATA Alliance for Patient Education.
Bite Me Cancer is a member of the ATA Alliance for Patient Education.

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Description

The American Thyroid Association announces Viswanath Gunda as the recipient of a 2016 research grant for his project on thyroid cancer treatment. His project explores combinatorial approaches to treating thyroid cancer.