Thyroid and Parathyroid Glands: Hormones & Imbalances

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Questions and Answers

Which of the following best describes the primary mechanism of action of calcitonin?

  • Decreasing bone formation and increasing bone breakdown, leading to increased blood calcium levels.
  • Inhibiting blood calcium level and decreasing bone formation.
  • Increasing bone formation and inhibiting bone breakdown, leading to decreased blood calcium levels. (correct)
  • Increasing blood calcium level and stimulating bone breakdown.

Why is iodine essential for normal thyroid function?

  • Iodine inhibits the production of thyroid-stimulating hormone (TSH).
  • Iodine decreases the metabolic rate.
  • Iodine directly stimulates the release of calcitonin.
  • Iodine is necessary for the formation of T3 and T4. (correct)

A patient with a known thyroid disorder is prescribed a beta blocker. How might this medication affect thyroid hormone levels?

  • Beta blockers decrease the need for iodine, thus normalizing thyroid function.
  • Beta blockers directly increase T3 and T4 levels.
  • Beta blockers can interfere with thyroid hormone levels, potentially affecting thyroid studies. (correct)
  • Beta blockers do not interfere with thyroid hormone levels.

Following a thyroidectomy, a patient reports tingling around their mouth and fingers. During a blood pressure check, you observe a carpal spasm. What is the priority nursing intervention?

<p>Immediately administer IV calcium gluconate. (D)</p> Signup and view all the answers

What is the primary role of the parathyroid gland in maintaining homeostasis?

<p>Regulating blood calcium levels. (C)</p> Signup and view all the answers

A patient with hyperparathyroidism is likely to have which of the following electrolyte imbalances?

<p>Hypercalcemia (A)</p> Signup and view all the answers

Why is an ECG indicated for patients with suspected parathyroid dysfunction?

<p>To monitor for potential changes in the QT interval related to calcium imbalances. (A)</p> Signup and view all the answers

A patient presents with flank pain and is later diagnosed with hyperparathyroidism. What is the likely connection between these two findings?

<p>The flank pain could be related to kidney failure due to hypercalcemia. (B)</p> Signup and view all the answers

Which of the following conditions is an example of primary hypothyroidism?

<p>Hypothyroidism caused by the thyroid gland not functioning properly. (C)</p> Signup and view all the answers

Severe head trauma resulting in hypothyroidism would be classified as which type of hypothyroidism?

<p>Secondary hypothyroidism (B)</p> Signup and view all the answers

What are the key clinical manifestations associated with Myxedema Coma?

<p>Generalized edema, altered mental status, and low temperature. (B)</p> Signup and view all the answers

What are common clinical manifestations of hypothyroidism in females?

<p>Heavy menstruation. (B)</p> Signup and view all the answers

A patient newly diagnosed with hypothyroidism is prescribed levothyroxine. What instructions regarding chest pain should the nurse provide?

<p>Call your health care provider if chest pain occurs. (A)</p> Signup and view all the answers

A patient taking levothyroxine has a heart rate of 104 bpm. What is the appropriate nursing intervention in this situation?

<p>Hold the levothyroxine and notify the health care provider. (B)</p> Signup and view all the answers

During the treatment of a patient experiencing Myxedema Coma, what is a priority nursing intervention at the bedside?

<p>Having suction equipment readily available (A)</p> Signup and view all the answers

In hyperthyroidism, what is the underlying pathology affecting the thyroid?

<p>Thyroid is hypersecreting hormones. (B)</p> Signup and view all the answers

What is the diagnostic hallmark of Graves' disease?

<p>High levels of TSH autoantibodies. (A)</p> Signup and view all the answers

A patient with Hashimoto's thyroiditis experiences thyroid cell destruction. What is the immediate consequence of this destruction?

<p>Increased release of stored T3 and T4. (D)</p> Signup and view all the answers

Which of the following is a life-threatening complication of hyperthyroidism?

<p>Thyroid storm. (B)</p> Signup and view all the answers

Priority patients need to be monitored closely when experiencing which clinical manifestations of hyperthyroidism?

<p>Delirium, further increases in temperature, increased peripheral pulses, or crackles in lungs. (B)</p> Signup and view all the answers

Following the administration of radioactive iodine, a patient shows signs of worsening hyperthyroidism with an increased temperature. What is the greatest concern for this patient?

<p>Thyroid storm. (D)</p> Signup and view all the answers

What cardiac monitoring is essential for patients experiencing thyroid storm?

<p>Telemetry monitoring for dysrhythmias. (A)</p> Signup and view all the answers

Addison's disease is characterized by which primary hormonal deficiency?

<p>Adrenocortical insufficiency with a deficiency in cortisol production. (A)</p> Signup and view all the answers

What is the primary underlying cause of Addison's disease?

<p>An autoimmune mechanism. (D)</p> Signup and view all the answers

Which of the following is a common secondary cause of Addison's disease?

<p>Corticosteroid therapy. (D)</p> Signup and view all the answers

What is the expected outcome of an ACTH stimulation test in a patient with primary Addison's disease?

<p>Failure to produce cortisol. (D)</p> Signup and view all the answers

A patient with Addison's disease is prescribed hydrocortisone. What is a critical teaching point regarding this medication?

<p>An emergency steroid kit should be readily available. (D)</p> Signup and view all the answers

What dietary recommendations are most appropriate for a patient with Addison's disease?

<p>High-sodium, high-carbohydrate, high-protein diet. (C)</p> Signup and view all the answers

What is the primary hormonal abnormality in Cushing's disease?

<p>Increased cortisol levels. (B)</p> Signup and view all the answers

Which set of electrolyte and glucose imbalances are typically seen in Cushing's disease?

<p>Hyperglycemia, hypokalemia, hypertension. (B)</p> Signup and view all the answers

A patient has clinical manifestations that are indicative of Cushing's disease. What diagnostic test will help to differentiate between primary and secondary conditions?

<p>Test for ACTH. (A)</p> Signup and view all the answers

A patient undergoes a dexamethasone suppression test. The morning cortisol level remains elevated. What does this result suggest?

<p>Possible adrenal or pituitary tumor or hypersecretion of cortisol. (D)</p> Signup and view all the answers

Which of the following medications is known to interfere with thyroid hormone levels, potentially affecting thyroid studies?

<p>Aspirin. (D)</p> Signup and view all the answers

Elevated temperature, diarrhea, and high heart rate might indicate which complication?

<p>Thyroid storm. (A)</p> Signup and view all the answers

What is the action that a patient with Addison's should take when participating in strenuous activity?

<p>Keep emergency steroid kit readily available (B)</p> Signup and view all the answers

What is the normal result of Dexamethasone Suppression Test?

<p>Decreased cortisol level (C)</p> Signup and view all the answers

What are the Clinical Manifestations of hyperthyroidism

<p>Elevated temp, Diarrheaand High HR (C)</p> Signup and view all the answers

What is the name of the medication used to primarily treat Hypothyroidism?

<p>Levothyroxine (B)</p> Signup and view all the answers

What is the primary cause of Addison's Disease?

<p>An autoimmune mechanism (D)</p> Signup and view all the answers

What are some complication of Primary Hypothyroidism?

<p>Myxedema Coma (B)</p> Signup and view all the answers

What symptoms would you see on someone with Cushing's Disease?

<p>Hyperglycemia, Hypokalemia, Hypertension (C)</p> Signup and view all the answers

Flashcards

Calcitonin

Secreted by thyroid gland cells, it increases bone formation, inhibits bone breakdown, and reduces blood calcium levels.

T3 and T4

These hormones, secreted by the thyroid, require iodine for production and regulate metabolic rate and growth.

Goiter

Enlargement of the thyroid gland often due to iodine deficiency or thyroid dysfunction.

Meds impacting thyroid levels

Medications like beta blockers, furosemide, and aspirin that can interfere with thyroid hormone levels.

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Post-Thyroidectomy Monitoring

Monitor for hypothyroidism and parathyroid issues (calcium imbalances).

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Trousseau's Sign

Spasm during blood pressure check indicates this, suggesting hypocalcemia. Immediately administer IV calcium gluconate.

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Parathyroid Gland

Gland that Monitors parathyroid hormone and calcium balance.

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Hyperparathyroidism

Often caused by a tumor; leads to increased PTH and elevated calcium levels.

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Calcium impact on ECG

Place the patient on ECG (think calcium affects QT Interval)

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Hyperparathyroid complication

Kidney Failure

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Primary Hypothyroidism

Thyroid gland itself is not functioning properly.

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Secondary Hypothyroidism

Hypothyroidism due to cancer, infection, neurosurgery, or head trauma.

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Myxedema Coma

Generalized edema, altered mental status, and low temperature; a severe complication of hypothyroidism.

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Hypothyroidism Symptoms

Heavy menstruation, muscle cramps, fatigue, anxiety, depression, and prolonged QT interval.

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Levothyroxine

Treatment for hypothyroidism; report chest pain to PCP.

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Levothyroxine precaution

Hold medication if HR is greater than 100.

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Myxedema Coma priority

Suction at the bedside is a priority.

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Hyperthyroidism

Thyroid gland hypersecreting thyroid hormones.

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Graves' Disease

High levels of TSH autoantibodies; sunlight can trigger headaches.

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Hashimoto's thyroiditis

Destruction of thyroid cells causing release of stored T3 and T4.

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Thyroid Storm

Elevated temp, diarrhea, and high HR; a severe complication of hyperthyroidism.

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Thyroid Storm Warning signs

Delirium, increasing temp, increased peripheral pulses, or crackles in lungs indicate...

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Radioactive iodine follow up

Monitor for worsening hyperthyroidism with increased temperature.

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Thyroid storm ECG

Cardiac monitor placement is needed for potential dysrhythmia.

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Addison's Disease

Adrenocortical insufficiency, where the patient cannot produce cortisol.

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Primary Addison's Cause

Autoimmune mechanism that causes the pt to not produce cortisol causing adrenal insufficiency.

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Secondary Addison's Cause

Corticosteroid therapy can suppress adrenal function.

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ACTH Stimulation Test (Addison's)

Patient fails to produce cortisol following ACTH administration.

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Hydrocortisone side effect

Patient will be immunosuppressed.

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Addison's Patient education

Keep emergency steroid kit readily available, avoid strenuous activity, and maintain a high-salt, high-carb, high-protein diet.

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Cushing's Disease

Increased/elevated cortisol levels.

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Cushing's symptoms triad

Hyperglycemia, hypokalemia, and hypertension.

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ACTH Test (Cushing's)

Differentiates between primary and secondary Cushing's conditions by measuring ACTH levels.

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Dexamethasone Suppression Test

1mg dexamethasone given PO at night, serum cortisol level obtained in AM normal result is decreased cortisol level. If it is high then this could mean tumor or hypersecretion of cortisol.

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Study Notes

  • Calcitonin, secreted by the thyroid gland, enhances bone formation, inhibits bone breakdown, and lowers blood calcium levels.
  • T3 and T4, thyroid hormones, require iodine for synthesis.
  • Imbalances in iodine levels can lead to goiter formation, affecting T3 and T4 production.
  • Thyroid hormones regulate metabolic rate and are crucial for normal growth and development.
  • Medications such as beta-blockers, furosemide (Lasix), and aspirin can interfere with thyroid level testing.
  • Following a thyroidectomy, monitor for hypothyroidism and parathyroid dysfunction.
  • Hypocalcemia S/S is spasm with obtaining of BP reading is referred to as Trousseau's sign, requiring immediate administration of IV calcium gluconate.
  • The parathyroid gland regulates parathyroid hormone (PTH) and calcium levels.
  • Changes in calcium, monitor ECG (QT Interval).
  • Hyperparathyroidism is often caused by a tumor, leading to increased PTH and elevated calcium levels.
  • Hyperparathyroidism can be asymptomatic or cause flank discomfort, potentially indicating kidney failure.

Hypothyroidism

  • Primary hypothyroidism results from thyroid gland dysfunction.
  • Secondary hypothyroidism can be caused by cancer, brain infection, neurosurgery, or severe head trauma.
  • A complication of hypothyroidism is Myxedema coma which presents with generalized edema, altered mental status, and low body temperature.
  • Clinical signs of hypothyroidism in females includes heavy menstruation, muscle cramping, fatigue, anxiety, depression, and prolonged QT interval.
  • Levothyroxine is used to treat hypothyroidism.
  • Call PCP if chest pain occurs when taking Levothyroxine
  • When taking Levothyroxine, monitor heart rate and hold if it exceeds 100 bpm.
  • Have suction available at bedside when treating patient with Myxedema Coma.

Hyperthyroidism

  • Hyperthyroidism involves excessive thyroid hormone secretion.
  • Graves' disease is characterized by high levels of TSH autoantibodies; sunlight/light may cause head pain.
  • Hashimoto's thyroiditis involves thyroid cell destruction, releasing stored T3 and T4.
  • Thyroid storm is a complication of hyperthyroidism characterized by elevated temperature, diarrhea, and high heart rate.
  • Priority assessments in Delirium pt with hyperthyroid includes monitoring for increasing temperature, increased peripheral pulses, or lung crackles.
  • Cardiac monitoring is essential due to the risk of dysrhythmia in hyperthyroid patient.
  • If receiving radioactive iodine ensure you monitor for signs of worsening hyperthyroid with increased temperature (THYROID STORM).

Addison’s Disease

  • Addison's disease is caused by adrenocortical insufficiency.
  • Primary Addison's disease is an autoimmune condition where the body cannot produce cortisol.
  • Secondary Addison's disease can result from corticosteroid therapy.
  • Diagnosis involves the Adrenocorticotropic Hormone (ACTH) stimulation test, where the patient fails to produce cortisol.
  • Treatment includes hydrocortisone, a steroid that causes immunosuppression.
  • Those with Addison's Disease should carry an emergency steroid kit and avoid strenuous activity, particularly in hot weather.
  • Diet modifications for Addison's include high salt, high carbohydrate, and high protein intake.

Cushing’s Disease

  • Cushing’s disease involves increased cortisol levels.
  • Clinical manifestations include hyperglycemia, hypokalemia, and hypertension.
  • Diagnosis involves testing ACTH to differentiate between primary and secondary conditions.
  • The Dexamethasone Suppression Test involves administering 1mg of dexamethasone orally at night and measuring serum cortisol levels in the morning; a normal result shows decreased cortisol levels.
  • Elevated cortisol levels may indicate a tumor or hypersecretion of cortisol.

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