Thrombosis

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Questions and Answers

What is a thrombus?

  • Compromised blood supply causing tissue damage
  • A detached intravascular mass carried by the blood to a distant site
  • The inappropriate activation of the normal haemostatic process
  • A solid mass of blood constituents formed in the vascular system (correct)

What is thrombosis?

  • Ischaemic necrosis due to occlusion of arterial supply or venous drainage
  • A detached intravascular mass carried by the blood to a distant site
  • Compromised blood supply causing tissue damage
  • The inappropriate activation of the normal haemostatic process (correct)

What is an embolus?

  • Ischaemic necrosis due to occlusion of arterial supply or venous drainage
  • Compromised blood supply causing tissue damage
  • The inappropriate activation of the normal haemostatic process
  • A detached intravascular mass carried by the blood to a distant site (correct)

What is ischaemia?

<p>Compromised blood supply causing tissue damage (D)</p> Signup and view all the answers

What is infarction?

<p>Ischaemic necrosis due to occlusion of arterial supply or venous drainage (D)</p> Signup and view all the answers

What does normal haemostasis allow blood to do?

<p>Exist as fluid in normal vessels (A)</p> Signup and view all the answers

What is included in Virchow's triad?

<p>Endothelial injury, alteration of blood flow, and hypercoagulability (D)</p> Signup and view all the answers

Flashcards

What is a thrombus?

A solid mass of blood components formed within the circulatory system.

What is thrombosis?

The inappropriate activation of the body's normal blood clotting process.

What is an embolus?

A detached mass that travels through the bloodstream to a new location.

What is ischaemia?

Compromised blood supply to a tissue, leading to potential damage.

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What is infarction?

Tissue death that occurs as a result of insufficient blood flow due to blocked arteries or veins.

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What does normal haemostasis allow blood to do?

Blood stays fluid inside normal blood vessels.

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What is included in Virchow's triad?

These are factors that contribute to the development of blood clots.

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Study Notes

  1. Thrombus is a solid mass of blood constituents formed in the vascular system.
  2. Thrombosis is the inappropriate activation of the normal haemostatic process.
  3. Embolus is a detached intravascular mass carried by the blood to a distant site.
  4. Ischaemia is compromised blood supply causing tissue damage.
  5. Infarction is ischaemic necrosis due to occlusion of arterial supply or venous drainage.
  6. Normal haemostasis allows blood to exist as fluid in normal vessels.
  7. Thromboembolic disease is caused by thrombosis, embolism, ischaemia, and infarction.
  8. Virchow's triad includes endothelial injury, alteration of blood flow, and hypercoagulability.
  9. Primary/genetic causes of hypercoagulability include factor V Leiden and antithrombin deficiency.
  10. Thromboembolism can cause DVT-PE and demonstrates adherence to the vascular endothelium and lines of Zahn upon histopathological examination.

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