Thorax Anatomy and Ventilation Mechanics
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Questions and Answers

Which of the following scenarios would most likely lead to an increase in airway resistance?

  • Decreased lung volume due to shallow breathing. (correct)
  • Increased levels of carbon dioxide in the alveoli.
  • Activation of the sympathetic nervous system.
  • Release of epinephrine during exercise.

How does an increase in anatomical dead space affect alveolar ventilation, assuming total pulmonary ventilation remains constant?

  • Alveolar ventilation decreases because a larger portion of each breath remains in the conducting zone. (correct)
  • Alveolar ventilation increases because more fresh air reaches the alveoli.
  • Alveolar ventilation initially decreases, but compensatory mechanisms quickly restore it to normal levels.
  • Alveolar ventilation remains unchanged as total pulmonary ventilation is constant.

A patient presents with rapid, shallow breathing. Which of the following sets of terms best describes this patient's condition?

  • Bradypnea and hypoventilation
  • Apnea and dyspnea
  • Eupnea and hyperventilation
  • Tachypnea and hypoventilation (correct)

If a person has a tidal volume of 500 mL and a respiratory rate of 12 breaths per minute, and their anatomical dead space is 150 mL, what is their alveolar ventilation per minute?

<p>4.2 L/min (D)</p> Signup and view all the answers

In a region of the lung where alveolar ventilation is reduced due to a partial airway obstruction, what compensatory mechanism helps to maintain efficient gas exchange?

<p>Local vasoconstriction of pulmonary arterioles, diverting blood flow away from the poorly ventilated alveoli. (C)</p> Signup and view all the answers

Which of the following best describes the relationship between intrapulmonary pressure and atmospheric pressure during inspiration?

<p>Intrapulmonary pressure is less than atmospheric pressure. (D)</p> Signup and view all the answers

A patient with emphysema experiences increased lung compliance. How does this condition most directly affect their respiratory function?

<p>It decreases the work required for inspiration but impairs the ability to exhale passively. (C)</p> Signup and view all the answers

According to Boyle's Law, if the volume of a container holding gas is doubled, what happens to the pressure of the gas, assuming temperature and number of moles remain constant?

<p>The pressure is halved. (C)</p> Signup and view all the answers

Which of the following scenarios would lead to an increase in airflow into the lungs, according to the principles of respiratory physiology?

<p>A decrease in intrapleural pressure during inspiration. (D)</p> Signup and view all the answers

A patient's pulmonary function test reveals a significantly reduced Vital Capacity (VC) but a normal Total Lung Capacity (TLC). Which type of lung disorder is most likely indicated by this combination of findings?

<p>Pulmonary fibrosis, a restrictive disorder. (C)</p> Signup and view all the answers

How do pulmonary surfactants affect lung function at the alveolar level?

<p>They decrease alveolar surface tension, preventing alveolar collapse. (A)</p> Signup and view all the answers

If a patient's tidal volume is 500 mL, their inspiratory reserve volume is 2500 mL, and their expiratory reserve volume is 1000 mL, what is their inspiratory capacity?

<p>3000 mL (D)</p> Signup and view all the answers

Which of the following occurs during expiration due to the elastic recoil of the lungs and thoracic wall?

<p>Increased intrapleural pressure. (A)</p> Signup and view all the answers

Flashcards

Airway Resistance

Opposition to airflow in the respiratory tract; influenced by airway diameter, mucus, and bronchoconstriction.

Anatomical Dead Space

The volume of air in the respiratory tract that doesn't participate in gas exchange.

Alveolar Ventilation

The amount of new air reaching the alveoli per minute, accounting for dead space.

Ventilation-Perfusion Coupling

Matching airflow to blood flow in the lungs to optimize gas exchange; regulated by local oxygen and carbon dioxide levels.

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Tachypnea

Rapid, shallow breathing. Elevated breath rate.

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External Respiration

Exchange of gases between atmosphere and blood.

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Airflow Pressure Gradient

Air flows from high to low pressure.

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Boyle's Law

Pressure of a gas is inversely proportional to its volume (at constant temperature).

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Dalton's Law

Total pressure of a gas mixture is the sum of partial pressures of each gas.

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Bronchoconstriction

Contraction of bronchiolar smooth muscle, decreasing airway diameter.

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Lung Compliance

Ease with which lungs and thorax expand.

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Pulmonary Surfactant

Substances that reduce surface tension in the alveoli.

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Residual Volume (RV)

Volume of air remaining in lungs after a maximal exhalation.

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Study Notes

  • This unit introduces the anatomy of the thorax and the mechanics of ventilation in the respiratory system.
  • Understanding the physical properties of air and pressure gradients is crucial for comprehending how air moves during breathing.
  • Pressure gradients facilitate air movement during breathing.

Key Functions of the Respiratory System

  • List the key functions of the respiratory system.

Anatomy of the Respiratory System

  • Describe the anatomy of the respiratory system and identify the role each structure plays in external respiration.
  • List in order the respiratory structures that air passes through during inspiration and expiration.

Mathematical Relationships in Respiratory Physiology

  • Define and explain the validity of the mathematical relationships for flow, resistance, partial pressures, and pressure-volume changes in respiratory physiology.
  • Mathematical relationships can be applied to predict gas behaviors and airflow changes in the respiratory system.
  • Boyle’s Law: There is an inverse relationship between gas pressure and volume; this is applied to explain airflow during inspiration and expiration.
  • Dalton’s Law explains the relationship between the total pressure of gases in a mixture and the partial pressure of an individual gas.
  • The relationship includes atmospheric pressure, intrapulmonary pressure, intrapleural pressure and transpulmonary pressure

Pulmonary Ventilation Factors

  • Pulmonary ventilation is affected by bronchiolar smooth muscle contractions (bronchoconstriction).
  • Pulmonary ventilation is affected by lung and thoracic wall compliance.
  • Pulmonary ventilation is affected by pulmonary surfactant and alveolar surface tension.

Lung Collapse

  • Forces tend to collapse the lungs ; these are normally opposed or prevented by other forces.
  • Elastic recoil of the lung versus subatmospheric intrapleural pressure also play a role.

Lung Volumes and Capacities

  • Define, identify, and determine values for the lung volumes (inspiratory reserve volume [IRV], tidal volume [TV], expiratory reserve volume [ERV], and residual volume [RV]).
  • Define, identify, and determine values for the lung capacities (inspiratory capacity [IC], functional residual capacity [FRC], vital capacity [VC], and total lung capacity [TLC]).

Lung Disorders

  • Differentiate between obstructive and restrictive lung disorders and provide examples of each.

Pressure Changes During Breathing

  • Describe and diagram the alveolar and intrapleural pressure changes that occur during inspiration and expiration.

Lung Compliance

  • Describe lung compliance as it relates to changes in transpulmonary pressure and lung volume.

Role of Surfactants

  • Explain the role of surfactants in respiratory physiology.

Airway Resistance

  • Factors affecting airway resistance, including local and reflex control mechanisms involved with variable resistance (bronchodilation and bronchoconstriction).

Anatomical Dead Space

  • Define anatomical dead space.
  • Explain how the anatomic dead space affects alveolar ventilation and total pulmonary ventilation including its effects on the composition of alveolar and expired air.

Types and Patterns of Ventilation

  • Describe differentiate between the types and patterns of ventilation including: eupnea, bradypnea, hyperventilation, hypoventilation, tachypnea, dyspnea, and apnea.

Ventilation Calculations

  • Define and calculate minute ventilation and alveolar ventilation.

Gas Composition in Alveoli

  • Gas composition in the alveoli remains relatively constant during normal breathing.
  • Demonstrate how gas composition might change during other breathing patterns.

Ventilation and Alveolar Blood Flow

  • Describe or diagram the mechanisms by which ventilation and alveolar blood flow are matched.
  • The effects of local changes in oxygen and carbon dioxide concentrations on the diameters of pulmonary arterioles and bronchioles need to be explained.
  • Use the mechanisms of ventilation-perfusion coupling to predict how reduced alveolar ventilation affects pulmonary blood flow distribution.
  • Use the mechanisms of ventilation-perfusion coupling to predict the effect of reduced pulmonary blood flow on bronchiole diameter.

Predicting Respiratory System Changes

  • Given a factor or situation (e.g., pulmonary fibrosis), predict the changes that could occur in the respiratory system and the consequences of those changes (i.e. given a cause, state a possible effect).

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Description

Explore the anatomy of the thorax and ventilation mechanics while investigating the functions of the respiratory system. Learn about pressure gradients and mathematical relationships in respiratory physiology. Understand how air moves during breathing.

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