30 Questions
Which mechanism of action of antibiotics involves the suppression of bacterial protein synthesis?
Induction of autolysis
What step is recommended in the prophylactic use of antibiotics to be carried out prior to a medical procedure?
Begin antibiotic administration 1 to 2 hours prior to the procedure
Which antibiotic agent is known to be highly antigenic (allergenic)?
Penicillins
Which antibiotic is associated with direct toxicity and extremely low allergenic effects?
Erythromycin
Which antibiotic shows direct toxicity leading to liver damage and tooth discoloration?
Tetracyclines
"When orally administered, 2/3rds or 3/4th of this antibiotic are destroyed in the stomach." Which antibiotic does this statement refer to?
Penicillin G
Which type of allergic reaction to penicillin is characterized by urticaria and anaphylactic shock?
Immediate (within 20 minutes)
What percentage of Penicillin V is absorbed when taken orally?
Approximately 65%
Which enzyme is effective against B-lactamase and is a component of Augmentin?
Clavulanic acid
Which of the following penicillins is semi-synthetic and stable against gastric acid?
Penicillin V
What type of organisms are more sensitive to Cephalosporins among Gram-positive and Gram-negative bacteria?
Gram-positive
Which antibiotic is safe in case of impaired renal function due to being detoxified in the liver?
Erythromycin
What is the drug of choice for orofacial infections caused by both aerobes and anaerobes?
Penicillin G
What is the primary route of administration for Clindamycin and Lincomycin?
Oral
Which antibiotic is characterized by a large macrolide ring and destroyed by gastric acid, necessitating an enteric coating?
Erythromycin
What adverse effect is extremely rare with Erythromycin?
Allergy
Which antibiotic has a greater effect against anaerobes compared to Erythromycin?
Clindamycin
What is the pharmacologic effect of Diazepam (Valium) according to the text?
Antianxiety
Which antibiotic exhibits cross-allergy with penicillin due to being chemically closely related to Cephalosporins?
Cefotaxime
Which of the following is NOT an adverse effect of Diazepam (Valium) as mentioned in the text?
Hypertension
Which of the following conditions is a contraindication for using Barbiturates based on the text?
Glaucoma
What is the adult oral dose range for Diazepam (Valium) based on the text?
2-10 mg
What is one of the differences between Barbiturates and Non-Barbiturates based on the text?
Cross-allergenicity
Which drug from the provided list is classified as a Non-Barbiturate and has sedative-hypnotic properties?
Methohexital (Brevital)
Which of the following tetracyclines is associated with major adverse effect pseudomembranous colitis?
Doxycycline (Vibramycin)
What is the spectrum of tetracyclines in terms of bacteria they are effective against?
Bacteriostatic to gram-positive and gram-negative bacteria
What is a common adverse effect of tetracyclines related to the developing dentition?
Staining of teeth
Which route of administration is recommended for metronidazole (Flagyl) to be effective against obligate anaerobic microorganisms?
Rectal administration
What is one of the significant contraindications for using tetracyclines?
Liver damage
Which tetracycline has the highest allergenic potential among the options provided?
Minocycline (Minocin, Vectrin)
Test your knowledge on the application of therapeutics in endodontics based on the teachings of Professor Maged Negm. Explore topics such as anxiety, pain management, infection control, and pharmacological sedation.
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