Therapeutic Renal Part

<p>60% (A)</p> Signup and view all the answers

<p>Increased hydration (D)</p> Signup and view all the answers

<p>Drug dosing (B)</p> Signup and view all the answers

<p>Acute kidney injury (AKI) (D)</p> Signup and view all the answers

<p>Non-steroidal anti-inflammatory drugs (NSAIDs) (C), Antibiotics (D)</p> Signup and view all the answers

<p>To estimate glomerular filtration rate (GFR) (D)</p> Signup and view all the answers

<p>Weight in pounds (C)</p> Signup and view all the answers

<p>To prevent further renal impairment (D)</p> Signup and view all the answers

<p>Estimating GFR in patients with renal dysfunction (C)</p> Signup and view all the answers

<p>It is less time-consuming and easier to obtain (A)</p> Signup and view all the answers

<p>Determine their ideal body weight (A)</p> Signup and view all the answers

<p>To establish a reference for future comparisons (D)</p> Signup and view all the answers

<p>Ibuprofen (A)</p> Signup and view all the answers

<p>A 50% rise from baseline in serum creatinine (D)</p> Signup and view all the answers

<p>Serum creatinine measurement (B)</p> Signup and view all the answers

<p>Acute renal failure (C), Decreased hydration (D)</p> Signup and view all the answers

<p>They can indicate low muscle mass (C)</p> Signup and view all the answers

<p>Most drug-induced renal impairments are reversible with prompt intervention. (D)</p> Signup and view all the answers

<p>Possible acute kidney injury (A)</p> Signup and view all the answers

<p>Age (B), Muscle mass (C)</p> Signup and view all the answers

<p>When acute kidney injury is suspected (A)</p> Signup and view all the answers

<p>0.7-1.5 mg/dL (B)</p> Signup and view all the answers

<p>Older age and female sex (D)</p> Signup and view all the answers

<p>Maintain adequate hydration (B)</p> Signup and view all the answers

<p>Chronic kidney disease (CKD) (C)</p> Signup and view all the answers

<p>Cockcroft-Gault formula (C)</p> Signup and view all the answers

<p>Calcineurin inhibitors (B)</p> Signup and view all the answers

<p>Assess baseline renal function (C)</p> Signup and view all the answers

<p>Dehydration (B)</p> Signup and view all the answers

<p>Pamidronate (A)</p> Signup and view all the answers

<p>By maintaining drug levels within the therapeutic range (B)</p> Signup and view all the answers

<p>Administer drugs and use the lowest effective dose (D)</p> Signup and view all the answers

<p>Aminoglycoside antibiotics and NSAIDs (D)</p> Signup and view all the answers

<p>Hemorrhagic shock and contrast media (B)</p> Signup and view all the answers

<p>Ensure adequate hydration and renal perfusion (B)</p> Signup and view all the answers

<p>Serum creatinine and urine output (D)</p> Signup and view all the answers

<p>Underlying kidney disease and dehydration (C)</p> Signup and view all the answers

<p>They can cause direct toxicity in the renal microenvironment (C)</p> Signup and view all the answers

<p>In patients with diabetes and chronic kidney disease (A)</p> Signup and view all the answers

<p>Initiate fluid resuscitation and renal replacement therapy (C)</p> Signup and view all the answers

<p>Prolonged use can increase the risk of renal injury (A)</p> Signup and view all the answers

<p>Administering more nephrotoxic agents (A)</p> Signup and view all the answers

Kidney problems caused by certain medications.

Kidney damage caused by a drug.

Sudden kidney failure; potentially serious.

Different types of medications, including prescription and OTC.

Acute kidney injury caused by medicine.

Drug-related kidney injuries can be common.

Closely watching how a medication affects the kidneys.

Changing medicine amounts based on kidney function.

Conditions that increase the likelihood of acute kidney injury (AKI).

Severe blood loss can lead to reduced blood flow to the kidneys, increasing the risk of AKI.

Contrast agents used in imaging procedures can directly damage kidney cells, increasing the risk of AKI.

Stronger drugs are more likely to cause kidney damage.

How a drug is given (e.g., IV, oral) can influence its impact on the kidneys.

Lack of fluids can worsen kidney function and increase the risk of AKI.

Prior kidney problems make a person more susceptible to drug-induced kidney injury.

Taking multiple medications simultaneously can increase the risk of kidney damage.

Maintaining adequate hydration and renal perfusion before contrast administration is crucial to prevent AKI.

Closely observing a patient's kidney function (creatinine, urine output) is essential in case of AKI.

Acute kidney injury caused by reduced blood flow to the kidneys, often due to dehydration or low blood pressure.

Damage to the tiny filtering units in the kidneys (glomeruli), which can lead to protein in the urine and decreased kidney function.

Medications that lower blood pressure by blocking a hormone that constricts blood vessels, which can sometimes cause prerenal AKI.

Drugs that suppress the immune system, commonly used after transplant, which can sometimes cause prerenal AKI.

Pain relievers that reduce inflammation, which can sometimes cause prerenal AKI, especially with long-term use.

Medications that increase urine production, which can sometimes cause prerenal AKI if not used carefully.

Over-the-counter pain relievers, which can sometimes cause prerenal AKI, especially in high doses or with prolonged use.

Medications used to fight infections and cancer, which can sometimes cause glomerular injury.

A medication used for bone diseases, which can sometimes cause glomerular injury.

A state of dehydration where the body has insufficient fluids, which can worsen drug-induced kidney injury.

Measuring how well your kidneys filter waste. Important for prescribing medications safely.

A simple way to estimate GFR using age, weight, and blood creatinine levels.

A more accurate test of GFR by measuring creatinine in urine over 24 hours.

Drugs that can harm your kidneys.

Checking your kidney health before starting potentially harmful medications.

Regularly checking your kidney function while on nephrotoxic medications.

A specific calculation used in the Cockcroft-Gault formula to estimate GFR based on height and gender.

Acute kidney injury caused by medications. It's reversible if caught early and the drug is stopped.

A rise in serum creatinine levels after starting a new medication.

A 50% increase from baseline in serum creatinine, or a rise of 0.5 mg/dL or more if baseline is less than 2 mg/dL, or a rise of 1 mg/dL or more if baseline is greater than 2 mg/dL.

Urea nitrogen concentration in the blood, a byproduct of protein metabolism, filtered by the kidneys.

Indicates potential kidney problems, dehydration, GI bleeding, or a high-protein diet.

A byproduct of muscle breakdown filtered and secreted by the kidneys, but not reabsorbed.

Serum creatinine levels can be influenced by factors such as age and muscle mass, making it an imperfect indicator of kidney function.

Can indicate medication effects, renal disease, or other issues. Requires considering baseline, hydration, and patterns.

Carefully examining a patient's medication list to identify any potential causes of acute kidney injury.

Regularly checking creatinine and other kidney-related lab tests to detect and manage drug-induced AKI.