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Questions and Answers
Which discipline is NOT involved in Therapeutic Drug Monitoring (TDM)?
Which discipline is NOT involved in Therapeutic Drug Monitoring (TDM)?
- Pharmacology
- Pharmacokinetics
- Pathology (correct)
- Clinical Medicine
In which country did TDM service start in 1984?
In which country did TDM service start in 1984?
- Australia
- United States
- Malaysia (correct)
- Canada
When was TDM first introduced in clinical practice?
When was TDM first introduced in clinical practice?
- 1960s
- 1970s (correct)
- 1990s
- 1980s
What is the aim of TDM?
What is the aim of TDM?
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What are the specific indications for monitoring drug concentrations in body fluids?
What are the specific indications for monitoring drug concentrations in body fluids?
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Study Notes
Therapeutic Drug Monitoring (TDM)
- Pharmacy, Laboratory Medicine, and Clinical Pharmacology are disciplines involved in TDM.
History of TDM
- TDM service started in Australia in 1984.
- TDM was first introduced in clinical practice in 1960s.
Aim and Indications of TDM
- The aim of TDM is to optimize the therapy by maintaining a plasma concentration of drugs within a therapeutic range.
- Specific indications for monitoring drug concentrations in body fluids include:
- Drugs with a narrow therapeutic index
- Patients with severe liver or kidney impairment
- Patients receiving multiple medications
- Patients not responding to treatment as expected
- Suspected toxicity or adverse reactions
- Patients with changing renal or hepatic function
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Test your knowledge on Therapeutic Drug Monitoring (TDM) with this quiz! Learn about the interpretation, monitoring, and communication of drug concentrations in the body to optimize medicine efficacy and minimize toxicity.
