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Tablets are the most widely used ______ dosage forms
oral
Advantages of tablets include convenient and ______
compliance
Disadvantages of tablets include inflexible dosage form and ______ difficulties
swallowing
Tablet size and shape can vary, such as discoid, oval, square, pentagonal, etc.
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Dimetapp is a film-coated ______
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Enteric coated ______ include Dulcolax and Arthrotec
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Buccal ______ are placed between the cheek and gums and dissolve slowly
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Sublingual ______ are placed under the tongue for quick dissolution
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Chewable ______ are meant to be chewed before swallowing and often contain sugars or flavoring agents
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Lozenges, troches, and lollipops are dissolved slowly in the mouth for localized effects and can be prepared by fusion or candy ______ process
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Multiple compressed ______ are made by more than one compression and can be used for extended release
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Buffered ______ are prepared with buffers to minimize drug irritation to the upper GI tract
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Effervescent ______ release carbon dioxide when placed in water
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Instant disintegrating/dissolving ______ are designed to quickly disintegrate without the need for chewing or liquid
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Tablet triturates, also known as molded ______, are made for oral administration by a pharmacist
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Common tablet production methods include wet granulation, dry granulation, and direct ______
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Advantages of gelatin capsules include ______ convenient easily compounded exact doses (compared to other powder dose forms) can be sealed oily (non-polar) liquids can be filled commercial capsule dosage forms can be made readily identifiable by different color combinations, printed letters or numbers on caps
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Disadvantages of gelatin capsules include cannot be filled with ______ polar liquids – water or glycerin, propylene glycol cannot be filled with very hygroscopic or deliquescent (melting) substances, or efflorescent substances not useful for volatile compounds since contents are usually released in the stomach, drugs that are irritating to the stomach may cause nausea (vs. enteric coated tablet) capsules will soften or become sticky if stored in un-sealed containers under humid, tropical conditions
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A common gelatin capsule size is ______ 000 00 0 1 2 3 4 5
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Examples of drugs that can be filled in gelatin capsules include ______ Aspirin 1040 650 520 325 260 195 160 100 Quinine Sulfate 650 390 325 225 195 130 100 65 Sodium Bicarbonate 1430 975 715 510 390 325 260 130
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Common gelatin capsule excipients include ______ Diluents o Bulking agents o e.g. lactose monohydrate, microcrystalline cellulose, mannitol, magnesium carbonate Lubricants o lubricants keep the formulation ingredients sticking to the machine parts and to improve formulation flow in the machine o e.g. magnesium stearate – usually.
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The gelatin capsule manufacturing process involves ______ Preparation o o o o Gelatin solution is moulded onto metallic pins Pin bars are removed and dried Capsule halves are stripped from the pins Cap and base are cut to proper length and joined
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The approximate capacity of gelatin capsules depends on the ______ Capsule Size and Volume (mL)
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A disadvantage of gelatin capsules is that they may ______ soften or become sticky if stored in un-sealed containers under humid, tropical conditions
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Study Notes
Overview of Tablet Production and Types of Tablets
- Dimetapp is a film-coated tablet (FCT) with Aquacoat and LustreClear as film coatings.
- Enteric coated tablets (ECT) include Dulcolax and Arthrotec.
- Buccal tablets are placed between the cheek and gums and dissolve slowly.
- Sublingual tablets are placed under the tongue for quick dissolution, such as Nitroglycerin and Lorazepam.
- Chewable tablets are meant to be chewed before swallowing and often contain sugars or flavoring agents.
- Lozenges, troches, and lollipops are dissolved slowly in the mouth for localized effects and can be prepared by fusion or candy molding process.
- Multiple compressed tablets are made by more than one compression and can be used for extended release.
- Buffered tablets are prepared with buffers to minimize drug irritation to the upper GI tract, like Tribuffered Aspirin.
- Effervescent tablets release carbon dioxide when placed in water, such as Alka-Seltzer.
- Instant disintegrating/dissolving tablets are designed to quickly disintegrate without the need for chewing or liquid, such as Zofran ODT.
- Tablet triturates, also known as molded tablets, are made for oral administration by a pharmacist.
- Common tablet production methods include wet granulation, dry granulation, and direct compression.
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Description
Test your knowledge on tablet production and the various types of tablets in this informative quiz. Learn about different coatings, administration methods, and production techniques used in the manufacturing of tablets. Challenge yourself to become an expert in the world of tablets!
