The Treg Cell Quiz
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Questions and Answers

True or false: Humoral immunity is the main defense against viruses, fungi, parasites, and some bacteria?

False

True or false: Cell-mediated immunity is the mechanism by which the body rejects transplanted organs?

True

True or false: CD4 and CD8 are types of antibodies?

False

True or false: Autoimmunity is the failure of tolerance in the immune system?

<p>True</p> Signup and view all the answers

True or false: Interferon gamma is primarily produced by Th1 cells?

<p>True</p> Signup and view all the answers

True or false: Interleukin 4 is produced by macrophages and Th2 cells?

<p>True</p> Signup and view all the answers

True or false: Th1 response is geared towards viral/bacterial attacks?

<p>True</p> Signup and view all the answers

True or false: Th2 response is geared towards parasitic/mucosal infections?

<p>True</p> Signup and view all the answers

True or false: IgG is the principal antibody molecule in response to the majority of infectious agents.

<p>True</p> Signup and view all the answers

True or false: IgE is responsible for immune control in the early response.

<p>False</p> Signup and view all the answers

True or false: IgM antibodies are present in saliva, tears, and breast milk.

<p>False</p> Signup and view all the answers

True or false: IL-2 is primarily an inhibitory cytokine.

<p>False</p> Signup and view all the answers

True or false: T lymphocytes require antigen presentation by macrophages or dendritic cells in order to respond to a foreign antigen?

<p>True</p> Signup and view all the answers

True or false: B lymphocytes require CD4 T cell help for antibody production?

<p>True</p> Signup and view all the answers

True or false: Only 2-3% of T cells survive to exit the thymus as mature T cells.

<p>True</p> Signup and view all the answers

True or false: Antibodies can react only with the specific antigen that induced their formation?

<p>True</p> Signup and view all the answers

True or false: Immunoglobulin M (IgM) is very good at neutralization?

<p>True</p> Signup and view all the answers

True or false: B cell development is MHC restricted.

<p>False</p> Signup and view all the answers

True or false: B cells present antigens with MHCII to CD4T cells.

<p>True</p> Signup and view all the answers

True or false: T cells typically express high amounts of CTLA4 on the cell surface.

<p>False</p> Signup and view all the answers

True or false: Regulatory T cells are necessary to maintain peripheral tolerance to self antigens.

<p>True</p> Signup and view all the answers

True or false: Inducible Treg cells can be generated to self and foreign antigens after an inflammatory immune response.

<p>True</p> Signup and view all the answers

True or false: Failure in tolerance or immune control mechanisms can lead to the development of hypersensitivity reactions.

<p>True</p> Signup and view all the answers

True or false: Type I hypersensitivity reactions are immediate and involve sensitization of IgE-coated mast cells and basophils.

<p>True</p> Signup and view all the answers

True or false: Genetic susceptibility can be passed on from parents.

<p>True</p> Signup and view all the answers

True or false: Type II hypersensitivity reactions involve antibody-dependent cytotoxicity.

<p>True</p> Signup and view all the answers

True or false: Type III hypersensitivity reactions involve T lymphocytes.

<p>False</p> Signup and view all the answers

True or false: Type IV hypersensitivity reactions typically occur within 24-72 hours.

<p>True</p> Signup and view all the answers

True or false: Autoimmune diseases can result from the alteration of patient's own antigens.

<p>True</p> Signup and view all the answers

True or false: Immune suppression can be used as a treatment for autoimmune diseases.

<p>True</p> Signup and view all the answers

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