The Role of CTLs and Tumor Neoantigens
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Questions and Answers

Which cells are responsible for killing tumor cells in the immune response against tumors?

  • Macrophages
  • NK cells
  • B cells
  • CTLs (correct)

    • What type of antigens do tumor neoantigens belong to?

  • Exogenously synthesized antigens
  • Endogenously synthesized antigens (correct)
  • Secreted antigens
  • Membrane-bound antigens

    • What is the role of CD8+ T cells in tumor rejection?

  • To inhibit the activation of CTLs
  • To produce antibodies against tumor antigens
  • To present tumor antigens to naive CD4+ T cells
  • To kill cells producing tumor antigens (correct)

    • Which cells are responsible for transporting tumor antigens to the lymph nodes?

    <p>Dendritic cells</p> Signup and view all the answers

    What is the process called when tumor antigens are processed and displayed by class I MHC molecules on dendritic cells?

    <p>Cross-presentation</p> Signup and view all the answers

    What may stimulate the expression of costimulators on antigen-presenting cells (APCs) in the context of tumors?

    <p>Innate responses</p> Signup and view all the answers

    Which type of T cells are able to migrate back to the tumor site and kill tumor cells without requiring costimulation or T cell help?

    <p>CD8+ T cells</p> Signup and view all the answers

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