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Questions and Answers
Which cells are responsible for killing tumor cells in the immune response against tumors?
Which cells are responsible for killing tumor cells in the immune response against tumors?
- Macrophages
- NK cells
- B cells
- CTLs (correct)
What type of antigens do tumor neoantigens belong to?
What type of antigens do tumor neoantigens belong to?
- Exogenously synthesized antigens
- Endogenously synthesized antigens (correct)
- Secreted antigens
- Membrane-bound antigens
What is the role of CD8+ T cells in tumor rejection?
What is the role of CD8+ T cells in tumor rejection?
- To inhibit the activation of CTLs
- To produce antibodies against tumor antigens
- To present tumor antigens to naive CD4+ T cells
- To kill cells producing tumor antigens (correct)
Which cells are responsible for transporting tumor antigens to the lymph nodes?
Which cells are responsible for transporting tumor antigens to the lymph nodes?
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What is the process called when tumor antigens are processed and displayed by class I MHC molecules on dendritic cells?
What is the process called when tumor antigens are processed and displayed by class I MHC molecules on dendritic cells?
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What may stimulate the expression of costimulators on antigen-presenting cells (APCs) in the context of tumors?
What may stimulate the expression of costimulators on antigen-presenting cells (APCs) in the context of tumors?
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Which type of T cells are able to migrate back to the tumor site and kill tumor cells without requiring costimulation or T cell help?
Which type of T cells are able to migrate back to the tumor site and kill tumor cells without requiring costimulation or T cell help?
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