7 Questions
Which cells are responsible for killing tumor cells in the immune response against tumors?
CTLs
What type of antigens do tumor neoantigens belong to?
Endogenously synthesized antigens
What is the role of CD8+ T cells in tumor rejection?
To kill cells producing tumor antigens
Which cells are responsible for transporting tumor antigens to the lymph nodes?
Dendritic cells
What is the process called when tumor antigens are processed and displayed by class I MHC molecules on dendritic cells?
Cross-presentation
What may stimulate the expression of costimulators on antigen-presenting cells (APCs) in the context of tumors?
Innate responses
Which type of T cells are able to migrate back to the tumor site and kill tumor cells without requiring costimulation or T cell help?
CD8+ T cells
Test your knowledge on the key immune mechanism of tumor eradication through CTLs and the role of tumor neoantigens. Explore the processing of cytosolic and nuclear proteins and their recognition by class I MHC-associated peptides. Challenge your understanding of tumor immunity in this quiz.
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