Podcast
Questions and Answers
What is the significance of anti-Oka identified in 1979?
What is the significance of anti-Oka identified in 1979?
- It was reactive in the pretransfusion testing phase
- It was named after Mrs. Kobutso's parents
- It was the first antibody found in the Ok system
- It caused reduced survival of Ok(a-) RBCs injected into the original antibody maker (correct)
Which chromosome harbors the BSG gene responsible for the Ok system antigens?
Which chromosome harbors the BSG gene responsible for the Ok system antigens?
- Chromosome 13
- Chromosome 1
- Chromosome 19 (correct)
- Chromosome 24
What is the main function of CD147 or basigin in relation to the Ok system?
What is the main function of CD147 or basigin in relation to the Ok system?
- Receptor and adhesion functions (correct)
- Antibody production stimulation
- Plasmodium falciparum inhibition
- Immune response modulation
Which high-prevalence antigen of the Ok system is also known as OKGV?
Which high-prevalence antigen of the Ok system is also known as OKGV?
What is the clinical significance of Oka being resistant to treatment with ficin, papain, DTT, and glycine-acid EDTA?
What is the clinical significance of Oka being resistant to treatment with ficin, papain, DTT, and glycine-acid EDTA?
How many high-prevalence antigens are there in the Ok system?
How many high-prevalence antigens are there in the Ok system?
What was the outcome when Cr-labeled Ok(a+) RBCs were injected into the original antibody maker?
What was the outcome when Cr-labeled Ok(a+) RBCs were injected into the original antibody maker?
What is the function of BASIGIN in relation to Plasmodium falciparum invasion?
What is the function of BASIGIN in relation to Plasmodium falciparum invasion?
What is the status of Ok(a-) RBC's among 400 individuals?
What is the status of Ok(a-) RBC's among 400 individuals?
What was Mrs. Kobutso's relationship with her parents?
What was Mrs. Kobutso's relationship with her parents?
Which high-prevalence antigen in the Ok system is carried on CD147, also known as basigin?
Which high-prevalence antigen in the Ok system is carried on CD147, also known as basigin?
Where is the BSG gene, responsible for the Ok system antigens, located?
Where is the BSG gene, responsible for the Ok system antigens, located?
What type of antibody was the original anti-Oka?
What type of antibody was the original anti-Oka?
What is the clinical significance of Ok(a) being resistant to treatment with DTT?
What is the clinical significance of Ok(a) being resistant to treatment with DTT?