14 Questions
What is the significance of anti-Oka identified in 1979?
It caused reduced survival of Ok(a-) RBCs injected into the original antibody maker
Which chromosome harbors the BSG gene responsible for the Ok system antigens?
Chromosome 19
What is the main function of CD147 or basigin in relation to the Ok system?
Receptor and adhesion functions
Which high-prevalence antigen of the Ok system is also known as OKGV?
OKGV or OK2
What is the clinical significance of Oka being resistant to treatment with ficin, papain, DTT, and glycine-acid EDTA?
Reduced susceptibility to enzyme treatment
How many high-prevalence antigens are there in the Ok system?
3
What was the outcome when Cr-labeled Ok(a+) RBCs were injected into the original antibody maker?
Reduced RBC survival rate
What is the function of BASIGIN in relation to Plasmodium falciparum invasion?
Receptor essential for invasion
What is the status of Ok(a-) RBC's among 400 individuals?
All are Ok(a-)
What was Mrs. Kobutso's relationship with her parents?
They were cousins
Which high-prevalence antigen in the Ok system is carried on CD147, also known as basigin?
OK1 or Ok(a+, a-)
Where is the BSG gene, responsible for the Ok system antigens, located?
Chromosome 19 at position 19p13.3
What type of antibody was the original anti-Oka?
IgG
What is the clinical significance of Ok(a) being resistant to treatment with DTT?
Decreased RBC survival
Test your knowledge on the historical perspective of the Ok (024) System, including the discovery of Anti-Oka in 1979 and the clinical significance of Ok(a-) RBCs. Explore the background and key facts related to antigens and antibodies in this quiz.
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