consalez

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

Which of the following cell types are part of nervous tissue?

  • Erythrocytes
  • Osteocytes
  • Neurons (correct)
  • Chondrocytes

What type of neuron has one axon and one dendrite?

  • Multipolar
  • Unipolar
  • Pseudounipolar
  • Bipolar (correct)

Which glial cells are responsible for myelination in the central nervous system?

  • Microglial cells
  • Ependymal cells
  • Astrocytes
  • Oligodendrocytes (correct)

What is the main function of astrocytes?

<p>Provide support and regulate the environment around neurons (A)</p> Signup and view all the answers

Which type of cell lines the ventricles of the brain and helps to create cerebrospinal fluid?

<p>Ependymal cells (D)</p> Signup and view all the answers

What glial cells act as the primary immune cells of the CNS?

<p>Microglial cells (D)</p> Signup and view all the answers

Gaps in the myelin sheath along an axon are called what?

<p>Nodes of Ranvier (D)</p> Signup and view all the answers

Which structure is responsible for connecting the cell body to the axon?

<p>Axon hillock (B)</p> Signup and view all the answers

What are the main components of the peripheral nervous system?

<p>Nerves and ganglia (B)</p> Signup and view all the answers

What is the name of the connective tissue layer that surrounds an entire nerve?

<p>Epineurium (D)</p> Signup and view all the answers

Which nervous system controls involuntary functions like heart rate and digestion?

<p>Autonomic nervous system (A)</p> Signup and view all the answers

Which of the following is a division of the autonomic nervous system?

<p>Sympathetic (D)</p> Signup and view all the answers

What term refers to the cell body of a neuron?

<p>Soma (C)</p> Signup and view all the answers

What is the name for the numerous extensions of a neuron that receive signals?

<p>Dendrites (D)</p> Signup and view all the answers

Nissl bodies are best described as which of the following?

<p>Rough endoplasmic reticulum (D)</p> Signup and view all the answers

A neuron typically has how many axons?

<p>One (D)</p> Signup and view all the answers

The 'cytosol' of a neuron refers to which of the following?

<p>The fluid inside the cell (D)</p> Signup and view all the answers

Which structure is considered a major site of protein synthesis in the neuron?

<p>Rough endoplasmic reticulum (A)</p> Signup and view all the answers

What accounts for the basophilic staining properties of Nissl bodies?

<p>The presence of RNA in ribosomes (A)</p> Signup and view all the answers

Which of the following best describes the function of the Golgi apparatus?

<p>Processes and packages proteins (B)</p> Signup and view all the answers

What is the function of the neuronal membrane?

<p>To isolate the cytoplasm from the surrounding fluid (A)</p> Signup and view all the answers

What is the main function of dendrites?

<p>To receive signals from other neurons (C)</p> Signup and view all the answers

Where are polyribosomes often observed clearly in neurons?

<p>In the dendrites (D)</p> Signup and view all the answers

What is the main purpose of the axon?

<p>Transmit information away from the cell body (D)</p> Signup and view all the answers

What is the range of the axon diameter in humans?

<p>Less than 0.1 μm to about 25 μm (B)</p> Signup and view all the answers

Axons often branch into what structures?

<p>Axon collaterals (A)</p> Signup and view all the answers

The cytoskeleton of a neuron is composed of what?

<p>Microtubules, neurofilaments, and microfilaments (C)</p> Signup and view all the answers

What is the function of neurofilaments?

<p>Provide structural support to the neuron (C)</p> Signup and view all the answers

Which structures are involved in the transport of materials throughout the cell?

<p>Microtubules (A)</p> Signup and view all the answers

Which of the following is a function of actin filaments?

<p>Involved in cell shape and cell motility (D)</p> Signup and view all the answers

Which proteins are responsible for vesicle transport along microtubules?

<p>Kinesin and dynein (D)</p> Signup and view all the answers

Proteins are transported from the soma to the axon terminal by what process?

<p>Axoplasmic transport (D)</p> Signup and view all the answers

Wallerian degeneration refers to the degradation of what part of the neuron?

<p>The axon (C)</p> Signup and view all the answers

How can anterograde axoplasmic transport be best described?

<p>Vesicle movement from the soma to the terminal (A)</p> Signup and view all the answers

At a synapse, electrical impulses are typically converted into what type of signal?

<p>Chemical (D)</p> Signup and view all the answers

What are the small bubbles of membrane that contain neurotransmitters called?

<p>Synaptic vesicles (B)</p> Signup and view all the answers

What is the name for the space between the presynaptic and postsynaptic membranes?

<p>Synaptic cleft (D)</p> Signup and view all the answers

Neurotransmitters are stored in vesicles within what part of the neuron?

<p>Axon terminal (B)</p> Signup and view all the answers

Electrical synapses contain what type of junctions?

<p>Gap junctions (C)</p> Signup and view all the answers

Which structure is unique to neurons and specialized for transmitting information?

<p>Axon (A)</p> Signup and view all the answers

What is the main component of Nissl bodies?

<p>Rough endoplasmic reticulum (A)</p> Signup and view all the answers

What accounts for the basophilic staining properties of Nissl substance?

<p>Presence of RNA in ribosomes (D)</p> Signup and view all the answers

What is a primary function of the Golgi apparatus in neurons?

<p>Protein sorting (A)</p> Signup and view all the answers

What is the term for branches that occasionally arise from axons?

<p>Axon collaterals (C)</p> Signup and view all the answers

What cells are capable of electrical signaling in nervous tissue?

<p>Neurons (D)</p> Signup and view all the answers

What is the Greek etymology of the term 'glia'?

<p>Glue (A)</p> Signup and view all the answers

From which embryonic structure do CNS glial cells originate?

<p>Ectoderm (A)</p> Signup and view all the answers

Which of these glial cell types is ONLY derived from the mesoderm?

<p>Microglia (B)</p> Signup and view all the answers

Which glial cells surround the cell bodies of neurons in PNS ganglia?

<p>Satellite cells (D)</p> Signup and view all the answers

Which glial cells are involved in the repair of PNS axons after injury?

<p>Schwann cells (C)</p> Signup and view all the answers

What type of glial cell helps regulate ion, nutrient and gas concentrations in the CNS?

<p>Astrocytes (B)</p> Signup and view all the answers

Which of the following is a key function of microglia?

<p>Immune defense and debris removal (B)</p> Signup and view all the answers

What feature is characteristic of astrocytes when viewed in H&E staining?

<p>Evident, compact, and dense nuclei (D)</p> Signup and view all the answers

Which structural feature is present in fibrous astrocytes, located in the CNS white matter?

<p>Long, thin, poorly branched processes (C)</p> Signup and view all the answers

What glial filament is highly abundant in astrocytes?

<p>GFAP (B)</p> Signup and view all the answers

What is the shape of astrocyte nuclei?

<p>Ovoid (B)</p> Signup and view all the answers

What type of junctions do astrocytes form?

<p>Tight junctions and gap junctions (C)</p> Signup and view all the answers

What is the function of astrocytes in response to brain injury?

<p>Produce the glial scar (A)</p> Signup and view all the answers

What role do astrocytes play in synaptic activity?

<p>They modulate synaptic activity (A)</p> Signup and view all the answers

How do astrocytes contribute to ionic homeostasis in the extracellular fluid?

<p>Removing extracellular K+ (D)</p> Signup and view all the answers

How do astrocytes help maintain constant pH levels in the cerebrospinal fluid (CSF)?

<p>Refilling Na+ and Ca2+ used in action potentials (B)</p> Signup and view all the answers

What is the role of radial glial cells during brain development?

<p>Serving as primary progenitor cells (B)</p> Signup and view all the answers

What role do radial glial cells play in neuron migration?

<p>Acting as a scaffold and guide (D)</p> Signup and view all the answers

What type of cells form the blood-brain barrier (BBB)?

<p>Endothelial cells (A)</p> Signup and view all the answers

What type of junctions exist between endothelial cells comprising the BBB?

<p>Tight junctions (A)</p> Signup and view all the answers

What is one of the key functions performed by the BBB?

<p>Protecting the brain from fluctuations in ionic composition (C)</p> Signup and view all the answers

What specialized structures cover the apical membrane of choroidal ependymal cells?

<p>Stereocilia (A)</p> Signup and view all the answers

What is the main function of the choroid plexus?

<p>Producing cerebrospinal fluid (CSF) (A)</p> Signup and view all the answers

What structure does the spinal cord connect to rostrally?

<p>Medulla oblongata (D)</p> Signup and view all the answers

Approximately how many pairs of spinal nerves are there?

<p>31 (A)</p> Signup and view all the answers

What type of axons are carried by the dorsal roots?

<p>Afferent (A)</p> Signup and view all the answers

Where are cell bodies of dorsal root axons located?

<p>Dorsal root ganglia (A)</p> Signup and view all the answers

At what level does the spinal cord typically end in adults?

<p>L1-L2 (D)</p> Signup and view all the answers

What is the collection of lumbar and sacral spinal nerves called?

<p>Cauda equina (C)</p> Signup and view all the answers

Through what openings do spinal nerves leave the vertebral canal?

<p>Intervertebral foramina (B)</p> Signup and view all the answers

The central core of the spinal cord is primarily made up of what?

<p>Grey matter (D)</p> Signup and view all the answers

What structure is found in the centre of the spinal cord?

<p>Central canal (C)</p> Signup and view all the answers

What distinct shape does the central core have?

<p>H (A)</p> Signup and view all the answers

What kind of neurons are contained in the anterior horn?

<p>Motor (C)</p> Signup and view all the answers

The posterior horn is the site of termination for many ______.

<p>Afferent neurons (B)</p> Signup and view all the answers

At what levels only is the lateral horn found?

<p>Thoracic and lumbar (B)</p> Signup and view all the answers

Which division of the autonomic nervous system do the neurons in the lateral horn belong to?

<p>Sympathetic (B)</p> Signup and view all the answers

What type of matter contains longitudinal nerve fibers?

<p>White matter (D)</p> Signup and view all the answers

Ascending tracts carry information to what part of the body?

<p>The brain (C)</p> Signup and view all the answers

Which ascending tracts carry fine touch and proprioception?

<p>Dorsal columns (B)</p> Signup and view all the answers

Which ascending tracts carry pain, temperature, coarse touch and pressure?

<p>Spinothalamic tracts (C)</p> Signup and view all the answers

Which of the following controls skilled voluntary movements?

<p>Lateral corticospinal tract (A)</p> Signup and view all the answers

What structures make up the brainstem?

<p>Medulla oblongata, pons, and midbrain (C)</p> Signup and view all the answers

What vital functions are controlled by centers in the brainstem?

<p>Breathing, circulation of blood, and consciousness (C)</p> Signup and view all the answers

The medulla oblongata is located in what position relative to the spinal cord?

<p>Rostral (C)</p> Signup and view all the answers

What is located on the ventral part of the pons?

<p>A bulge (B)</p> Signup and view all the answers

What does the medulla and pons border on their dorsal sides?

<p>Fourth ventricle (B)</p> Signup and view all the answers

What is anterior to the cerebral aqueduct?

<p>Tegmentum (B)</p> Signup and view all the answers

How many pairs of cranial nerves exist?

<p>12 (A)</p> Signup and view all the answers

Which cranial nerves attach directly to the forebrain?

<p>I and II (C)</p> Signup and view all the answers

Which of the following best describes the location of the cerebellum?

<p>Dorsal to the brainstem (D)</p> Signup and view all the answers

What is the tentorium cerebelli?

<p>A dural flap (C)</p> Signup and view all the answers

What parts is the cerebellum split nominally into?

<p>Inferior, middle, superior (A)</p> Signup and view all the answers

What is the outer layer of the cerebellum made up of?

<p>Grey matter (D)</p> Signup and view all the answers

What is the name for a convolution of the cerebellum?

<p>Folia (A)</p> Signup and view all the answers

What is the cerebellum concerned with?

<p>Coordination of movement (C)</p> Signup and view all the answers

Rostral (anterior) to the pons, is the relatively small

<p>Midbrain (C)</p> Signup and view all the answers

What makes up the forebrain?

<p>Diencephalon and cerebral hemispheres (C)</p> Signup and view all the answers

What area are the epithalamus, thalamus, subthalamus and hypothalamus found in?

<p>Diencephalon (C)</p> Signup and view all the answers

From a ventral view of the hypothalamus in the midline, what structure arises?

<p>The infundibulum (B)</p> Signup and view all the answers

What does the lateral fissure divide the hemisphere into?

<p>Four lobes (B)</p> Signup and view all the answers

What are the names of the convolutions and furrows in the cerebral cortex?

<p>Gyri, sulci (C)</p> Signup and view all the answers

What does the precentral gyrus contain?

<p>Primary motor cortex (C)</p> Signup and view all the answers

What senses exist at the highest level of representation in other areas, excluding the occipital lobe?

<p>Vision and hearing (A)</p> Signup and view all the answers

What kind of structure is a limb lobe?

<p>Nervous (A)</p> Signup and view all the answers

The embryonic central canal of the spinal cord shrinks to give rise to what structure?

<p>Ependymal canal (D)</p> Signup and view all the answers

What covers the ependymal cells?

<p>Cilia (D)</p> Signup and view all the answers

The ventricles are lined by what?

<p>Ependymal cells (C)</p> Signup and view all the answers

In terms of direction, does it move progressively in a dorsal direction or ventral direction?

<p>Dorsal direction (C)</p> Signup and view all the answers

How is the ventricular system connected?

<p>Cerebral aqueduct (D)</p> Signup and view all the answers

The lateral walls of the third ventricle are formed by which specific structres?

<p>the thalamus and hypothalamus (B)</p> Signup and view all the answers

What fluid does the ventricular system contain?

<p>Cerebrospinal fluid (CSF) (D)</p> Signup and view all the answers

What cells secrete the cerebrospinal fluid?

<p>Choroid plexus cells (B)</p> Signup and view all the answers

What structure helps control CSF pressure?

<p>Arachnoid granulations (A)</p> Signup and view all the answers

What structure is the spinal cord continuous with rostrally?

<p>Medulla oblongata (C)</p> Signup and view all the answers

How many pairs of spinal nerves are attached to the spinal cord?

<p>31 (B)</p> Signup and view all the answers

What is the approximate length of the spinal cord?

<p>40-50 cm (D)</p> Signup and view all the answers

What is the name for the collection of lumbar and sacral spinal nerve roots that extend inferiorly from the conus medullaris?

<p>Cauda equina (C)</p> Signup and view all the answers

Through what structures do spinal nerves exit the vertebral canal?

<p>Intervertebral foramina (D)</p> Signup and view all the answers

What is the approximate diameter of the spinal cord?

<p>1-1.5 cm (B)</p> Signup and view all the answers

What divides the spinal cord into dorsal and ventral regions?

<p>Dorsal and Ventral Roots (B)</p> Signup and view all the answers

Which of the following contains sensory neuron?

<p>Dorsal Roots (D)</p> Signup and view all the answers

Where do efferent axons originate?

<p>Spinal grey matter (A)</p> Signup and view all the answers

At which vertebral level does the spinal cord typically end in adults?

<p>L1-L2 (B)</p> Signup and view all the answers

Which cranial nerve is associated with olfaction?

<p>Cranial nerve I (A)</p> Signup and view all the answers

Which cranial nerves are associated with taste?

<p>Cranial nerves VII and IX (A)</p> Signup and view all the answers

What type of sensory information is carried by spinal nerves?

<p>General Sensory Information from the trunk and limbs (D)</p> Signup and view all the answers

What cranial nerve carries general sensory information from the head?

<p>Trigeminal nerve (cranial nerve V) (D)</p> Signup and view all the answers

How many neurons are typically in the general sensation pathway?

<p>Three neurons (C)</p> Signup and view all the answers

Where does the first-order neuron enter the spinal cord?

<p>Through a spinal nerve (D)</p> Signup and view all the answers

What happens to the axon of the second-order neuron?

<p>It crosses over to the opposite side of the central nervous system (decussates). (C)</p> Signup and view all the answers

In which structure does the third-order neuron have its cell body?

<p>Thalamus (B)</p> Signup and view all the answers

To which area does the third-order neuron project?

<p>Somatosensory cortex (A)</p> Signup and view all the answers

The anterolateral system is primarily responsible for carrying which type of sensory information?

<p>Coarse touch, pain, and temperature (A)</p> Signup and view all the answers

Where do primary spinal afferents carrying pain and temperature information terminate?

<p>Near their level of entry into the spinal cord (A)</p> Signup and view all the answers

What is the other name for dorsal column pathway tract?

<p>Medial lemniscus pathway (C)</p> Signup and view all the answers

The dorsal columns system carries what type of sensory information?

<p>Fine touch and proprioception (C)</p> Signup and view all the answers

What structure ascends ipsilateral to the spinal cord?

<p>Fasciculus gracilis and cuneatus (A)</p> Signup and view all the answers

Where does the axons of fasciculus gracilis and cuneatus terminate?

<p>Medulla oblongata (B)</p> Signup and view all the answers

Where do primary afferent fibers of the trigeminal nerve terminate?

<p>Ipsilaterally in the trigeminal sensory nucleus (B)</p> Signup and view all the answers

Axons from which structure decussate across the midline?

<p>Trigeminal nucleus (D)</p> Signup and view all the answers

What is meant by "somatotopic organization"?

<p>Representation of the body in the cerebral cortex (D)</p> Signup and view all the answers

What is the name of the prominent ridge of the descending corticospinal fibers?

<p>Pyramid (A)</p> Signup and view all the answers

Which of these are the tracts for the control of skilled voluntary movements?

<p>Corticobulbar and corticospinal pathways (C)</p> Signup and view all the answers

The term 'peripheral nerve' refers to what?

<p>All nerve trunks and branches outside the CNS (A)</p> Signup and view all the answers

What is the primary function of peripheral nerves?

<p>To communicate between the brain/spinal cord and the rest of the body (A)</p> Signup and view all the answers

A typical peripheral nerve consists of what?

<p>Numerous nerve fibers (A)</p> Signup and view all the answers

Nerve fibers in peripheral nerves can be classified as what?

<p>Both afferent and efferent (D)</p> Signup and view all the answers

Within peripheral nerves, nerve fibers are arranged in what?

<p>Bundles (A)</p> Signup and view all the answers

What surrounds the bundles of nerve fibers within peripheral nerves?

<p>Connective tissue sheaths (D)</p> Signup and view all the answers

What is the connective tissue layer that directly surrounds individual nerve fibers?

<p>Endoneurium (D)</p> Signup and view all the answers

What is the connective tissue layer that surrounds a bundle of nerve fibers (fascicle)?

<p>Perineurium (A)</p> Signup and view all the answers

What is the outermost connective tissue layer that ensheathes the entire nerve?

<p>Epineurium (D)</p> Signup and view all the answers

The cranial and spinal meninges are continuous with which structures?

<p>Connective tissue sheaths of spinal and cranial nerves (C)</p> Signup and view all the answers

Which meningeal layer is continuous with the endoneurium?

<p>Pia mater (C)</p> Signup and view all the answers

What is the term for the degeneration of the distal portion of a transected nerve fiber?

<p>Wallerian degeneration (C)</p> Signup and view all the answers

Following nerve transection, what may happen to the proximal portion of the neuron?

<p>It may survive and regenerate (C)</p> Signup and view all the answers

The more distal the nerve transection, the ______ likely the cell body is to survive.

<p>More (D)</p> Signup and view all the answers

What is indicated by the dispersal and loss of staining of Nissl granules?

<p>Signs of degeneration (chromatolysis) (D)</p> Signup and view all the answers

During nerve regeneration, what role do endoneurial tubes play for new fibers?

<p>They guide entering regenerating fibers (C)</p> Signup and view all the answers

What is the rate of growth of new nerve fibers during peripheral nerve regeneration?

<p>1-2 mm/day (D)</p> Signup and view all the answers

In the context of nerve damage, what does 'distal areflexia' refer to?

<p>Absence of reflexes (D)</p> Signup and view all the answers

What are the two pathological types listed in the lecture for peripheral neuropathies?

<p>Demyelinating and axonal (A)</p> Signup and view all the answers

What is the functional outcome of nerve fibers being redistributed in the spinal nerves?

<p>They form individual peripheral nerves (C)</p> Signup and view all the answers

Each spinal nerve is responsible for?

<p>Sensory innervation for a part of the body surface (A)</p> Signup and view all the answers

The area of skin supplied by a single spinal nerve is called what?

<p>Dermatome (C)</p> Signup and view all the answers

A group of muscles innervated for movement are known as what?

<p>Myotome (C)</p> Signup and view all the answers

The peripheral nervous system consists of what?

<p>Nerve endings, peripheral nerve trunks, plexuses and ganglia (D)</p> Signup and view all the answers

What do sensory receptors detect?

<p>Changes in the internal and external environments (B)</p> Signup and view all the answers

What is the main function of efferent nerve endings?

<p>To control muscle contraction and secretory gland activity (B)</p> Signup and view all the answers

Nerve endings are classified as what?

<p>Afferent or efferent (D)</p> Signup and view all the answers

Afferent nerve endings respond to which type of stimuli?

<p>Mechanical, thermal, and chemical (C)</p> Signup and view all the answers

What type of signal is conducted by nerve fibers of afferent nerve endings?

<p>Action potentials to the CNS (C)</p> Signup and view all the answers

Nerve endings that induce movement are specifically called what?

<p>Motor (C)</p> Signup and view all the answers

Nerve endings that induce cellular secretion are called what?

<p>Secretomotor (C)</p> Signup and view all the answers

What are the two sensory systems in the body?

<p>General and special (B)</p> Signup and view all the answers

Exteroceptors respond to what stimuli?

<p>Temperature, touch and pressure (C)</p> Signup and view all the answers

Proprioceptors provide awareness of what?

<p>Posture and movement (kinesthesia) (B)</p> Signup and view all the answers

What are the four characteristics of stimulus?

<p>Modality, intensity, duration and location (A)</p> Signup and view all the answers

What happens to a receptor when it is adequately stimulated?

<p>A Generator Potential Occurs (A)</p> Signup and view all the answers

Select the correct description of Slowly adapting receptors.

<p>Respond Continuously (D)</p> Signup and view all the answers

Morphologically, one way the receptors may be classified is as...

<p>Encapsulated or nonencapsulated (B)</p> Signup and view all the answers

Mechanoreceptors respond to what stimuli?

<p>Deformation or displacement (A)</p> Signup and view all the answers

The term 'peripheral nerve' applies to which of the following?

<p>Nerve trunks and branches that lie outside the CNS. (D)</p> Signup and view all the answers

Which of the following best describes the role of peripheral nerves?

<p>They are the communication route between the brain/spinal cord and the rest of the body. (C)</p> Signup and view all the answers

A typical peripheral nerve is composed of:

<p>Numerous nerve fibers. (D)</p> Signup and view all the answers

What type of nerve fibers are found in peripheral nerves?

<p>Either afferent or efferent. (D)</p> Signup and view all the answers

Within peripheral nerves, how are nerve fibers arranged?

<p>In bundles. (A)</p> Signup and view all the answers

What is the name for the connective tissue surrounding individual nerve fibers?

<p>Endoneurium. (C)</p> Signup and view all the answers

Bundles of nerve fibers are surrounded by:

<p>Perineurium. (B)</p> Signup and view all the answers

The whole nerve is ensheathed by a tough coat known as:

<p>Epineurium. (D)</p> Signup and view all the answers

The arachnoid mater is continuous with which connective tissue layer of a peripheral nerve?

<p>Perineurium. (C)</p> Signup and view all the answers

What is the largest part of the hindbrain?

<p>Cerebellum (C)</p> Signup and view all the answers

From which aspect of the brainstem does the cerebellum originate?

<p>Dorsal (B)</p> Signup and view all the answers

Which structure does the cerebellum overlie?

<p>Fourth ventricle (A)</p> Signup and view all the answers

How many pairs of fiber bundles connect the cerebellum to the brainstem?

<p>Three (C)</p> Signup and view all the answers

What are the fiber bundles that connect the cerebellum to the brainstem called?

<p>Cerebellar peduncles (A)</p> Signup and view all the answers

Which of the following is NOT the name of a cerebellar peduncle?

<p>Anterior (D)</p> Signup and view all the answers

Which part of the brainstem do the inferior cerebellar peduncles connect to?

<p>Medulla oblongata (C)</p> Signup and view all the answers

To what part of the brainstem do the middle cerebellar peduncles connect?

<p>Pons (D)</p> Signup and view all the answers

To which part of the brainstem do the superior cerebellar peduncles connect the cerebellum?

<p>Midbrain (C)</p> Signup and view all the answers

What is the primary function of the cerebellum?

<p>Motor functions (B)</p> Signup and view all the answers

At what level of consciousness does the cerebellum primarily operate?

<p>Unconscious (A)</p> Signup and view all the answers

Which function is primarily controlled by the cerebellum?

<p>Equilibrium maintenance (A)</p> Signup and view all the answers

Besides coordinating movement, the cerebellum also influences what?

<p>Posture and muscle tone (A)</p> Signup and view all the answers

Which cerebellar peduncle contains mostly efferent axons?

<p>Superior (D)</p> Signup and view all the answers

Which cerebellar peduncle contains both afferent and efferent axons?

<p>Inferior (B)</p> Signup and view all the answers

Where is the tentorium cerebelli positioned?

<p>On top of the cerebellum (B)</p> Signup and view all the answers

Which structure does the free border of the tentorium cerebelli encircle?

<p>Midbrain (B)</p> Signup and view all the answers

What is the name for the raised midline region on the superior surface of the cerebellum?

<p>Vermis (C)</p> Signup and view all the answers

The cerebellum is composed of how many laterally located hemispheres?

<p>Two (B)</p> Signup and view all the answers

What structure joins the two hemispheres of the cerebellum?

<p>Vermis (D)</p> Signup and view all the answers

What are the folds on the surface of the cerebellum called?

<p>Folia (D)</p> Signup and view all the answers

How are the folia oriented on the surface of the cerebellum?

<p>Transversely (B)</p> Signup and view all the answers

What landmark separates the anterior lobe from the posterior lobe on the superior surface of the cerebellum?

<p>Primary fissure (D)</p> Signup and view all the answers

Which fissure demarcates the flocculonodular lobe on the underside of the cerebellum?

<p>Posterolateral fissure (B)</p> Signup and view all the answers

What are the outer and inner layers of the cerebellum primarily composed of?

<p>Gray and white matter, respectively (B)</p> Signup and view all the answers

What type of fibers primarily make up the white matter of the cerebellum?

<p>Afferent and efferent fibers (A)</p> Signup and view all the answers

What is the formation of afferent and efferent fibers in the cerebellum called?

<p>Arbor vitae (A)</p> Signup and view all the answers

What is found within the cerebellar white matter?

<p>Nuclei (C)</p> Signup and view all the answers

How many bilaterally-paired cerebellar nuclei are buried deep within the white matter?

<p>Four (C)</p> Signup and view all the answers

What do the cerebellar nuclei primarily constitute?

<p>Output of the cerebellum (A)</p> Signup and view all the answers

With which structures do the cerebellar nuclei have important connections?

<p>Brainstem and thalamus (C)</p> Signup and view all the answers

What term describes the highly convoluted structure of the cerebellar cortex?

<p>Foliated (B)</p> Signup and view all the answers

What type of neurons primarily reside within the cerebellar cortex?

<p>Cerebellar neurons (A)</p> Signup and view all the answers

To what level do the spinocerebellar tracts carry afferent information?

<p>Subconscious level (C)</p> Signup and view all the answers

From what structures do the spinocerebellar fibers derive information?

<p>Muscle spindles and mechanoreceptors (C)</p> Signup and view all the answers

What broader function do the spinocerebellar pathways primarily control?

<p>Posture and coordination of movement (D)</p> Signup and view all the answers

The fibers of the dorsal spinocerebellar tract originate from which segments of the spinal cord?

<p>T1-L2 (B)</p> Signup and view all the answers

Where do the axons of the dorsal spinocerebellar tract enter the cerebellum?

<p>Inferior cerebellar peduncle (C)</p> Signup and view all the answers

What sensory organs are associated with the ventral spinocerebellar tract (Gower's)?

<p>Golgi tendon organs (C)</p> Signup and view all the answers

What canal does the spinal cord occupy?

<p>Vertebral spinal canal (A)</p> Signup and view all the answers

What is the spinal cord continuous with rostrally?

<p>Medulla oblongata (D)</p> Signup and view all the answers

Into how many segments is the spinal cord divided?

<p>8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal (B)</p> Signup and view all the answers

Which segments make up the cervical enlargement of the spinal cord?

<p>C4-T1 (D)</p> Signup and view all the answers

Which segments are associated with the lumbar enlargement?

<p>L1-S3 (A)</p> Signup and view all the answers

What structure is formed as the spinal cord tapers caudally to the lumbar enlargement?

<p>Conus medullaris (D)</p> Signup and view all the answers

Where does the filum terminale attach?

<p>First coccygeal vertebra (C)</p> Signup and view all the answers

When does the spinal cord occupy the entire length of the vertebral canal?

<p>During the third month of fetal life (D)</p> Signup and view all the answers

At what level does the spinal cord typically terminate in adults?

<p>The intervertebral disc between L1 and L2 (C)</p> Signup and view all the answers

How many pairs of spinal nerves does the spinal cord bear?

<p>31 (B)</p> Signup and view all the answers

What aspects of the spinal cord are spinal nerves attached to?

<p>Dorsolateral and ventrolateral (A)</p> Signup and view all the answers

Dorsal nerve roots contain which type of neurons?

<p>Afferent (D)</p> Signup and view all the answers

Cell bodies of afferent neurons that bring sensory information from skin, muscles, and joints lie in which ganglia?

<p>Dorsal root (D)</p> Signup and view all the answers

What type of axons do ventral roots of the spinal nerves carry?

<p>Efferent (A)</p> Signup and view all the answers

Which spinal nerve does not have a dorsal root?

<p>C1 (B)</p> Signup and view all the answers

Where do the C2-C7 spinal nerves exit?

<p>Above the corresponding vertebrae (A)</p> Signup and view all the answers

If spinal nerves divide after leaving the intervertebral foramina, what do they produce?

<p>Dorsal and ventral rami (C)</p> Signup and view all the answers

What region does the dorsal ramus supply?

<p>Muscles and skin of the back (B)</p> Signup and view all the answers

What is lumbar puncture used to remove?

<p>Cerebrospinal fluid (CSF) (C)</p> Signup and view all the answers

What feature divides the spinal cord into two symmetrical halves?

<p>Ventral median fissure (D)</p> Signup and view all the answers

What does the outer part of the spinal cord consist of?

<p>White matter (A)</p> Signup and view all the answers

What shape is the gray matter of the spinal cord?

<p>H-shaped (B)</p> Signup and view all the answers

Where do many afferent fibers entering in the dorsal root terminate?

<p>Dorsal horn (B)</p> Signup and view all the answers

Where can the cell bodies of motor neurons be found?

<p>Ventral horn (D)</p> Signup and view all the answers

In which spinal cord segments is a lateral horn located?

<p>Thoracic and upper lumbar (D)</p> Signup and view all the answers

In what zone do fibers intertwine with thin and thick fibers, giving a reticular appearance?

<p>Lamina I (marginal zone of Waldeyer) (D)</p> Signup and view all the answers

What type of information is related to pain and temperature sensation?

<p>Pain and temperature (A)</p> Signup and view all the answers

Which of the following lamina is known as the substantia gelatinosa of Rolando?

<p>Lamina II (D)</p> Signup and view all the answers

What do the dorsal and ventral horns of the gray matter contain?

<p>Interneurons (A)</p> Signup and view all the answers

When are spinal interneurons typically inhibited?

<p>When one particular response pathway is activated (B)</p> Signup and view all the answers

Into what are dorsal roots formed?

<p>Spinal nerves (C)</p> Signup and view all the answers

Fibers in Lissauer’s tracts divide to form what?

<p>Ascending and descending branches (C)</p> Signup and view all the answers

What type of neuron releases glutamic acid to the spinal cortex?

<p>Excitatory (D)</p> Signup and view all the answers

Which structures are inhibited by the touch of large-diameter afferents?

<p>Nociceptive impulses (C)</p> Signup and view all the answers

What fibers conduct the sensation of hot and cold stimuli?

<p>Thermoceptors (B)</p> Signup and view all the answers

Which areas of the spine contain well the most developed alpha and gamma motor neurons?

<p>Cervical and Lumbar enlargements (B)</p> Signup and view all the answers

What main function is served by the spinal cord and its associated spinal nerves?

<p>Receiving afferent fibers, controlling trunk/limb movements, and providing autonomic innervation (A)</p> Signup and view all the answers

What anatomical feature is the spinal cord continuous with rostrally?

<p>Medulla oblongata (D)</p> Signup and view all the answers

The spinal cord is protected by the vertebral column and occupies which specific location?

<p>Vertebral spinal canal (D)</p> Signup and view all the answers

How many coccygeal segments does the spinal cord typically have?

<p>1 (D)</p> Signup and view all the answers

Which spinal cord segments make up the cervical enlargement?

<p>C4-T1 (A)</p> Signup and view all the answers

The lumbar enlargement provides innervation for which region of the body?

<p>Lower limb (C)</p> Signup and view all the answers

The conus medullaris is what?

<p>Conical tapering of the spinal cord (C)</p> Signup and view all the answers

What is the filum terminale?

<p>A connective tissue strand (C)</p> Signup and view all the answers

In adults, where does the spinal cord typically terminate?

<p>At the level of the intervertebral disc between L1 and L2 (A)</p> Signup and view all the answers

What is the cauda equina?

<p>A collection of nerve roots (B)</p> Signup and view all the answers

From what aspects of the spinal cord do the spinal nerves originate?

<p>Dorsolateral and ventrolateral (C)</p> Signup and view all the answers

What forms the dorsal and ventral nerve roots?

<p>Groups of contiguous fascicles (B)</p> Signup and view all the answers

Dorsal and ventral nerve roots pass through what structures?

<p>Intervertebral foramina (A)</p> Signup and view all the answers

What is contained in the cell bodies within the dorsal root ganglia (DRG)?

<p>Sensory neurons (C)</p> Signup and view all the answers

What type of axons are carried by the ventral roots of the spinal nerves?

<p>Efferent (D)</p> Signup and view all the answers

Where are the cell bodies of the efferent axons found?

<p>Ventral horns (B)</p> Signup and view all the answers

Which nerve does not have a dorsal root, and why not?

<p>C1 - provides no sensory innervation to the skin (D)</p> Signup and view all the answers

The spinal nerve C8 leaves below which vertebra?

<p>C7 (D)</p> Signup and view all the answers

After leaving the intervertebral foramina, what do spinal nerves divide into?

<p>Dorsal and ventral rami (C)</p> Signup and view all the answers

Which region of the body is supplied by the dorsal ramus of a spinal nerve?

<p>Back (D)</p> Signup and view all the answers

What is supplied by the ventral ramus of the spinal nerve?

<p>Front of the body and limbs (A)</p> Signup and view all the answers

What is the purpose of a lumbar puncture?

<p>To remove CSF for diagnostic purposes (B)</p> Signup and view all the answers

Through what structure does the central canal connect rostrally?

<p>Cerebral aqueduct (C)</p> Signup and view all the answers

Bundles of what component primarily make up the white matter of the spinal cord?

<p>Ascending and descending axons (B)</p> Signup and view all the answers

What anatomical shape approximates the spinal cord's gray matter?

<p>H (D)</p> Signup and view all the answers

Which of the following structures are protrusions of the gray matter?

<p>Dorsal and ventral horns (C)</p> Signup and view all the answers

Which root does the body of motor neurons lie adjacent to?

<p>Dorsal (C)</p> Signup and view all the answers

Which spinal cord segments contain a lateral horn?

<p>Thoracic and lumbar (D)</p> Signup and view all the answers

Afferent fibers entering through the dorsal roots split into ascending a descending branches, what is the name of the structure that some of these fibers travel in?

<p>Lissauer's Tract (B)</p> Signup and view all the answers

What is dorsal horn mainly associated with?

<p>Sensory Functions (D)</p> Signup and view all the answers

Collaterals of what type of afferents are received by the substantia gelatinosa (Rexed's laminae I-III)?

<p>Smallest diameter myelinated (group A delta) and unmyelinated (C) (B)</p> Signup and view all the answers

When referring to interneurons in the dorsal horn synapsing with nociceptive afferent axons, what peoptides are released?

<p>Enkephalin (A)</p> Signup and view all the answers

What is the name for area containing spinal reflexes that lie in the dorsal horn.

<p>Clarke's Column (B)</p> Signup and view all the answers

What is the medial group wihin lamina VIII (of lamina IX) responsible for innervating?

<p>Epaxial muscle groups (A)</p> Signup and view all the answers

What specific part of the body does the phrenic nerve innervate?

<p>Diaphragm (B)</p> Signup and view all the answers

What actions may the interneurons in the dorsal horn play a role in?

<p>Modifying sensory information and ongoing movement (B)</p> Signup and view all the answers

What afferent signals are ascending spinal tracts responsible for?

<p>Pain, thermal, tactile, muscle and joint (B)</p> Signup and view all the answers

The first order of primary afferent neuron runs through the what structre?

<p>Dorsal Root (C)</p> Signup and view all the answers

In the Dorsal Column system, what type of information is carried relating to the body?

<p>Sensory information relating to the ipsilateral side (C)</p> Signup and view all the answers

Which area does both nuclei gracilis and cuneatus ascend to without interruption?

<p>Medulla Oblongata (B)</p> Signup and view all the answers

How do the axons from the second-order neurons ascend through the brainstem?

<p>Medial Lemniscus (A)</p> Signup and view all the answers

Which of the following is part of the diencephalon?

<p>Hypothalamus (B)</p> Signup and view all the answers

The forebrain consists of which structures?

<p>Diencephalon and cerebral hemispheres (A)</p> Signup and view all the answers

Which part of the diencephalon is the largest?

<p>Thalamus (A)</p> Signup and view all the answers

The thalamus has extensive reciprocal connections with what structure?

<p>Cerebral cortex (C)</p> Signup and view all the answers

Which structure receives impulses from the cerebellum and basal ganglia?

<p>Thalamus (A)</p> Signup and view all the answers

Which of the following can be seen on the base of the brain?

<p>Hypothalamus (A)</p> Signup and view all the answers

The infundibulum extends from what structure?

<p>Tuber cinereum (B)</p> Signup and view all the answers

Which structures are located caudal to the tuber cinereum on either side of the midline?

<p>Mammillary bodies (A)</p> Signup and view all the answers

The hypothalamus has important connections with which system?

<p>Limbic system (C)</p> Signup and view all the answers

The diencephalon forms the lateral wall of what?

<p>Third ventricle (C)</p> Signup and view all the answers

Which part of the ventricular wall is formed by the thalamus?

<p>Dorsal (A)</p> Signup and view all the answers

Which part of the diencephalon is located in its most caudal and dorsal region?

<p>Epithalamus (D)</p> Signup and view all the answers

The epithalamus primarily consists of what?

<p>Pineal gland and habenula (B)</p> Signup and view all the answers

Which hormone does the pineal gland synthesize?

<p>Melatonin (D)</p> Signup and view all the answers

The sleep/waking cycle is also known as the:

<p>Circadian rhythm (C)</p> Signup and view all the answers

Which of the following is linked by a pathway including the septum, hypothalamus and monoaminergic nuclei?

<p>Brainstem (D)</p> Signup and view all the answers

Extending anteriorly from the habenula is the:

<p>Stria medullaris (D)</p> Signup and view all the answers

The subthalamic nucleus lies against what structure?

<p>Internal capsule (D)</p> Signup and view all the answers

The subthalamic nucleus has prominent connections with the globus pallidus and the:

<p>Substantia nigra (D)</p> Signup and view all the answers

The zona incerta is a rostral extension of what?

<p>Brainstem reticular formation (D)</p> Signup and view all the answers

The zona incerta has pathways to integrate what sensory challenges?

<p>Exteroceptive and interoceptive (C)</p> Signup and view all the answers

With the hypothalamus, what does the thalamus form?

<p>Third ventricle (C)</p> Signup and view all the answers

In most individuals, the two thalami are joined by what?

<p>Interthalamic adhesion (C)</p> Signup and view all the answers

Another fascicle of nerve fibers with limbic connections that overlie the thalamus are called?

<p>Stria terminalis (A)</p> Signup and view all the answers

Which structure connects the amygdala with the bed nucleus and ventromedial nucleus of the hypothalamus?

<p>Stria terminalis (C)</p> Signup and view all the answers

Lateral to the thalamus lies what part of the internal capsule?

<p>Posterior limb (D)</p> Signup and view all the answers

What is the primary site of relay for all sensory pathways except olfaction?

<p>Thalamus (C)</p> Signup and view all the answers

The thalamus is a site where sensory inputs can be:

<p>Modulated (A)</p> Signup and view all the answers

Axons from thalamic neurons that project to the neocortex travel where?

<p>Internal capsule (B)</p> Signup and view all the answers

Which nuclei receive information specific to a sensory modality and project to a specific area of the neocortex?

<p>Specific nuclei (D)</p> Signup and view all the answers

What type of nuclei show broad and diffuse projections through the cerebral cortex?

<p>Nonspecific nuclei (C)</p> Signup and view all the answers

Specific thalamic nuclei have direct connections with which areas?

<p>Specific areas of the cerebral cortex (D)</p> Signup and view all the answers

The dorsal nuclei are in contact with what bodies?

<p>Medial and lateral geniculate (A)</p> Signup and view all the answers

The medial and lateral geniculate nuclei are collectively called what?

<p>Meta-thalamus (D)</p> Signup and view all the answers

What is the internal medullary lamina composed of?

<p>White matter (C)</p> Signup and view all the answers

The reticular thalamic nucleus (grey matter) is a thin shell of what?

<p>Neurons (B)</p> Signup and view all the answers

What does the metathalamus include?

<p>Nuclei that protrude from the posterior aspect of the pulvinar of the thalamus (C)</p> Signup and view all the answers

Almost all sensory pathways are relayed via the thalamus and project where?

<p>Cerebral cortex (D)</p> Signup and view all the answers

The anterior thalamic radiation projects to which lobe?

<p>Frontal lobe (A)</p> Signup and view all the answers

Which of the following structures is NOT part of the diencephalon?

<p>Cerebral hemisphere (D)</p> Signup and view all the answers

What other major brain structure is the forebrain rostral to?

<p>Midbrain (B)</p> Signup and view all the answers

What structure forms the dorsal part of the ventricular wall in the diencephalon?

<p>Thalamus (D)</p> Signup and view all the answers

Which hormone is synthesized by the pineal gland, a key component of the epithalamus?

<p>Melatonin (D)</p> Signup and view all the answers

Together with the hypothalamus, what does the thalamus form?

<p>The lateral wall of the third ventricle (D)</p> Signup and view all the answers

What general functional role is played by several nuclei within the thalamus?

<p>Relaying of almost all sensory information to the cortex (B)</p> Signup and view all the answers

Which area receives retinotopic input via the optic tract?

<p>Lateral Geniculate Nucleus (D)</p> Signup and view all the answers

The medial geniculate nucleus relays what type of information?

<p>Auditory (B)</p> Signup and view all the answers

What type of motor feedback does the ventral lateral nucleus receive from the cerebellum and basal ganglia?

<p>Direct (C)</p> Signup and view all the answers

With what is the medial dorsal nucleus of the thalamus associated?

<p>Emotions (B)</p> Signup and view all the answers

What areas are most sensory pathways relayed through?

<p>Thalamus (A)</p> Signup and view all the answers

Damage to the thalamus may lead to loss of sensation in what manner?

<p>Contralateral face and limbs (B)</p> Signup and view all the answers

What is one possible effect of continuous nicotine exposure on the brain?

<p>It selectively causes degeneration in axons from the habenula to the interpeduncular nucleus (D)</p> Signup and view all the answers

What is the shape of the subthalamic nucleus in a coronal section?

<p>Biconvex lens (C)</p> Signup and view all the answers

Damage to the medial portion of the dorsomedial nucleus may impair?

<p>Memory (C)</p> Signup and view all the answers

The cerebral hemisphere is derived from which embryological structure?

<p>Telencephalon (C)</p> Signup and view all the answers

Which part of the brain reaches the greatest degree of development in humans?

<p>Cerebral hemisphere (D)</p> Signup and view all the answers

What type of matter primarily composes the cerebral cortex?

<p>Gray matter (C)</p> Signup and view all the answers

What are the ridges of the cerebral cortex called?

<p>Gyri (C)</p> Signup and view all the answers

What are the furrows of the cerebral cortex called?

<p>Sulci (C)</p> Signup and view all the answers

Approximately what percentage of the cerebral cortex's surface area is hidden within the sulci?

<p>70% (B)</p> Signup and view all the answers

What type of tissue lies beneath the surface of the cerebral cortex?

<p>White matter (D)</p> Signup and view all the answers

What is the name for the band of fibers connecting the cerebral hemispheres?

<p>Corpus callosum (A)</p> Signup and view all the answers

Into how many lobes can each cerebral hemisphere be divided?

<p>Four (C)</p> Signup and view all the answers

What is the name of the deepest cleft on the lateral surface of the cerebral hemisphere?

<p>Lateral fissure (C)</p> Signup and view all the answers

Which lobe does the lateral fissure separate from the frontal and parietal lobes?

<p>Temporal lobe (A)</p> Signup and view all the answers

What is the name of the cortical area found deep within the lateral fissure?

<p>Insula (D)</p> Signup and view all the answers

What term refers to the parts of the frontal, parietal and temporal lobes that overlie the insula?

<p>Opercula (B)</p> Signup and view all the answers

Which lobe constitutes the entire region in front of the central sulcus?

<p>Frontal lobe (B)</p> Signup and view all the answers

Which gyrus lies immediately in front of the central sulcus?

<p>Precentral gyrus (A)</p> Signup and view all the answers

Which gyrus is the site of the primary somatosensory cortex?

<p>Postcentral gyrus (D)</p> Signup and view all the answers

Which sulcus is used to locate the primary visual cortex?

<p>Calcarine sulcus (C)</p> Signup and view all the answers

The temporal lobe lies beneath which fissure?

<p>Lateral fissure (C)</p> Signup and view all the answers

What area is included within the superior temporal gyrus?

<p>Primary auditory cortex (D)</p> Signup and view all the answers

Where are the transverse temporal gyri (Heschl's convolutions) located?

<p>Within the lateral fissure (A)</p> Signup and view all the answers

Which landmark is used to find the somatosensory cortex?

<p>Central sulcus (A)</p> Signup and view all the answers

Within which lobe is the primary visual cortex found?

<p>Occipital lobe (A)</p> Signup and view all the answers

What is the general function of the anterior part of the cerebrum (frontal lobe)?

<p>Motor Control (C)</p> Signup and view all the answers

What is the region immediately anterior to the primary motor cortex (Brodmann's area 6)?

<p>Premotor cortex (B)</p> Signup and view all the answers

Damage to the frontal eye field (Brodmann's area 8) typically causes what?

<p>Conjugate deviation of the eyes (D)</p> Signup and view all the answers

In most individuals, which hemisphere is responsible for the comprehension and expression of language?

<p>Left (D)</p> Signup and view all the answers

What is the functional role of the precentral gyrus?

<p>Primary motor cortex (A)</p> Signup and view all the answers

What Brodmann's area corresponds to the primary motor cortex?

<p>4 (C)</p> Signup and view all the answers

What is the organization called within the somatosensory cortex?

<p>Somatotopic organization (D)</p> Signup and view all the answers

Which cerebral cortex receives principal subcortical afferents from VL nucleus of thalamus?

<p>primary motor cortex (D)</p> Signup and view all the answers

On the medial surface of the hemisphere, where is the supplementary motor area located?

<p>premotor cortex (B)</p> Signup and view all the answers

Which is a primary function of the cortical areas designated as premotor?

<p>programming and preparation for movement (D)</p> Signup and view all the answers

Which cortical area most directly influences activity of the primary motor cortex?

<p>premotor cortex (C)</p> Signup and view all the answers

Where does Broca's motor speech area fall anatomically?

<p>inferior frontal gyrus of dominant hemisphere (B)</p> Signup and view all the answers

Which lobe does lie posterior to the frontal lobe?

<p>parietal lobe (A)</p> Signup and view all the answers

A somatosensory cortex and primary visual cortex is contained where?

<p>post central gyrus and calcarine sulcus (D)</p> Signup and view all the answers

What is known as the is the site at which thalamocortical axons terminate?

<p>post central gyrus (D)</p> Signup and view all the answers

Damage to right parietal lobe, an individual will have trouble with which of the following?

<p>copying/constructing design (D)</p> Signup and view all the answers

The insular cortex would be found location in which anatomical feature?

<p>In The depths of lateral fissure are (A)</p> Signup and view all the answers

Where would Heschl's gyri or transverse temporal gyri be located?

<p>deep superior bank superior (B)</p> Signup and view all the answers

The primary auditory cortex does receives signals from what thalamic nucleui?

<p>medial geniculate (A)</p> Signup and view all the answers

What visual portion also is complex and uncertain?

<p>cortical representation of the (D)</p> Signup and view all the answers

What part of the brain does the occipital lobe primarily cover?

<p>vision (B)</p> Signup and view all the answers

Which sulci marks location of primary visual cortex?

<p>calcarine (A)</p> Signup and view all the answers

Damage to the visual association cortex lead to what outcome?

<p>deficits visual interpretation (D)</p> Signup and view all the answers

What higher functions do the cerebral hemisphere control primarily, or exclusively?

<p>cognitive (B)</p> Signup and view all the answers

What skill is right cerebral hemisphere dominant for?

<p>music (A)</p> Signup and view all the answers

What is this condition called the inability to accurately name, describe, or identify them?

<p>associative agnosia (A)</p> Signup and view all the answers

What disease is a loss of episodic memory or called anterograde?

<p>Alzheimer's (B)</p> Signup and view all the answers

Which of these structures is part of the basal ganglia?

<p>Caudate nucleus (B)</p> Signup and view all the answers

Which anatomical structure is found in close proximity to the internal capsule?

<p>Globus pallidus (D)</p> Signup and view all the answers

What is the collective term for the caudate nucleus and putamen?

<p>Striatum (C)</p> Signup and view all the answers

Which lobe of the brain contains the amygdala?

<p>Temporal lobe (B)</p> Signup and view all the answers

Which of the following is the function of the nucleus accumbens?

<p>Reward and gratification (A)</p> Signup and view all the answers

With what system or area does the nucleus accumbens have close connections?

<p>Limbic system (C)</p> Signup and view all the answers

What is the primary role of the basal ganglia?

<p>Control of movement (C)</p> Signup and view all the answers

Which of the following is anatomically and functionally related to the caudate nucleus and putamen?

<p>Globus pallidus (B)</p> Signup and view all the answers

The lentiform nucleus is composed of which two structures?

<p>Putamen and globus pallidus (C)</p> Signup and view all the answers

What is another name for the lentiform nucleus?

<p>Lenticular nucleus (B)</p> Signup and view all the answers

Which of the following best describes the shape of the lentiform nucleus?

<p>Lens-shaped (C)</p> Signup and view all the answers

Which phrase refers to the phylogenetically more recent part of the striatum?

<p>Neostriatum (D)</p> Signup and view all the answers

The head of the caudate is almost completely separated from the putamen by which structure?

<p>Internal capsule (A)</p> Signup and view all the answers

Which part of the striatum constitutes the nucleus accumbens?

<p>Ventral and medial part (C)</p> Signup and view all the answers

Where does the tail of the caudate nucleus descend?

<p>Temporal lobe (D)</p> Signup and view all the answers

What separates the putamen from the globus pallidus?

<p>Lateral medullary lamina (B)</p> Signup and view all the answers

What structure contains cholinergic neurons, one of them being the nucleus basalis of Meynert?

<p>Substantia innominata (D)</p> Signup and view all the answers

In Alzheimer's disease, which neurons undergo degeneration?

<p>Cholinergic neurons of the nucleus basalis of Meynert (D)</p> Signup and view all the answers

Afferents to the striatum come from the cerebral cortex, the substantia nigra pars compacta, and the:

<p>Thalamus (D)</p> Signup and view all the answers

Projections from the frontal lobe project mainly to what structure?

<p>Putamen (D)</p> Signup and view all the answers

Which neurotransmitter is used by corticostriatal fibers that are excitatory to striatal neurons?

<p>Glutamic acid (A)</p> Signup and view all the answers

Which area are the intralaminar nuclei (centromedian and parafascicular nuclei) found in?

<p>Thalamus (D)</p> Signup and view all the answers

The nigrostriatal projection originates from which structure?

<p>Substantia nigra pars compacta (B)</p> Signup and view all the answers

Which substance is the neurotransmitter of the nigrostriatal pathway?

<p>Dopamine (B)</p> Signup and view all the answers

The D1 receptors transduce dopamine as what type of signal?

<p>Excitatory (C)</p> Signup and view all the answers

The ventral tegmental area (VTA) provides dopaminergic input to which structure?

<p>Nucleus accumbens (A)</p> Signup and view all the answers

What is the general organization of the basal ganglia circuitry?

<p>Parallel anatomical loops (D)</p> Signup and view all the answers

What type of movement is controlled by the oculomotor loop?

<p>Saccadic eye movements (B)</p> Signup and view all the answers

What structure is the main source of inputs to the limbic loop of the basal ganglia?

<p>Limbic association cortex (D)</p> Signup and view all the answers

To which nuclei does the ventral pallidum project fibers?

<p>Thalamic (A)</p> Signup and view all the answers

Which of the following are the 'input' portions of the basal ganglia?

<p>Caudate nucleus and putamen (B)</p> Signup and view all the answers

Medium spiny neurons are the cells of origin found in what brain structure?

<p>Striatum (D)</p> Signup and view all the answers

The cells (top) that project to the internal segment project are comprised of what?

Signup and view all the answers

The direct pathway disinhibits what?

Signup and view all the answers

Efferent striatal projections are inhibitory are utilize what?

Signup and view all the answers

Where does the principal projection of the external pallidum project to?

Signup and view all the answers

A small contingent of medial pallidal efferent fibers passes caudally to terminate where?

Signup and view all the answers

A homolog to the internal segment of the globus pallidus is the?

Signup and view all the answers

What is the function of the basal ganglia?

Signup and view all the answers

The combination of symptoms of basal ganglia depend on what?

Signup and view all the answers

What is the most common disorder of the basal ganglia?

Signup and view all the answers

Parkinson's disease is caused by degeneration of what?

Signup and view all the answers

What crosses the blood-brain barrier?

Signup and view all the answers

The term chorea is associated with the degeneration on what part of the brain?

Signup and view all the answers

Which of the following is considered part of the basal ganglia?

<p>All of the above (D)</p> Signup and view all the answers

The putamen and globus pallidus are sometimes collectively referred to as the:

<p>Lentiform nucleus (B)</p> Signup and view all the answers

Which part of the brain is the nucleus accumbens associated with?

<p>Reward and gratification (A)</p> Signup and view all the answers

The basal ganglia are primarily concerned with what?

<p>Control of movement (A)</p> Signup and view all the answers

Which structure has connections with the amygdala, linking the basal ganglia and the limbic system?

<p>Nucleus accumbens (A)</p> Signup and view all the answers

The caudate nucleus and putamen are collectively referred to as what?

<p>Striatum (D)</p> Signup and view all the answers

What is the function of the globus pallidus?

<p>Motor control (C)</p> Signup and view all the answers

Where is the amygdala located?

<p>Temporal lobe (C)</p> Signup and view all the answers

Which part of the brain does the ventral tegmental area (VTA) provide dopaminergic input to?

<p>Nucleus accumbens (A)</p> Signup and view all the answers

What is the main output of the basal ganglia?

<p>Thalamus (C)</p> Signup and view all the answers

Which broader brain region contains the hypothalamus?

<p>Diencephalon (C)</p> Signup and view all the answers

The hypothalamus is located ventral to what structure.

<p>Thalamus (D)</p> Signup and view all the answers

The hypothalamus contains nuclei that coordinate what type of responses?

<p>Integrated visceral (D)</p> Signup and view all the answers

What main function does the hypothalamus play in the body's response to infection?

<p>Fever production (D)</p> Signup and view all the answers

What division of the autonomic nervous system has the function of decreasing heart rate and is associated with the anterior hypothalamus?

<p>Parasympathetic (B)</p> Signup and view all the answers

What three organ systems does the hypothalamus control?

<p>Heart, lungs, gastrointestinal tract, and genitourinary organs (D)</p> Signup and view all the answers

What does the hypothalamus help regulate through hormonal control?

<p>Reproduction (B)</p> Signup and view all the answers

What is the volume of the hypothalamus in the brain?

<p>Less than 0.3% (C)</p> Signup and view all the answers

What is the weight of the hypothalamus?

<p>4 grams (D)</p> Signup and view all the answers

Name the caudal landmark for the hypothalamas.

<p>Mammillary body (A)</p> Signup and view all the answers

With what brain area does the lamina terminalis interconnect?

<p>Optic chiasm (B)</p> Signup and view all the answers

What behavior is relatively simple and stereotyped in lower animals and is directed to satisfying the drives of thirst, hunger, sex, and defense?

<p>Instinctive behavior (D)</p> Signup and view all the answers

Name the part of the brain that has neurons contributing to wakefulness by secreting the neuropeptide orexin (hypocretin).

<p>Lateral hypothalamic area (LHA) (D)</p> Signup and view all the answers

The LHA activates tuberomammillary neurons and what location in the pons, contributing to arousal and wakefulness.

<p>Locus coeruleus (A)</p> Signup and view all the answers

When are growth hormones released?

<p>during stage 3 and stage 4 sleep (C)</p> Signup and view all the answers

Lesions to what area result in insomnia?

<p>Preoptic area (D)</p> Signup and view all the answers

Damage to the Papez circuit is associated with what disorder?

<p>Wernicke-Korsakoff syndrome (B)</p> Signup and view all the answers

What structure extends from the hypothalamus to the pituitary gland?

<p>Infundibulum (D)</p> Signup and view all the answers

The median eminence, located at the base of the hypothalamus, serves as an interface between the neural and what other system?

<p>Endocrine (C)</p> Signup and view all the answers

What is a key function of the paraventricular and supraoptic nuclei?

<p>Water balance (D)</p> Signup and view all the answers

What symptoms might be produced by the destruction of the anterior nucleus

<p>Hyperthermia (C)</p> Signup and view all the answers

What hormone regulates the sleep/wake cycle?

<p>Melatonin (B)</p> Signup and view all the answers

What is the role of the blood brain barrier?

<p>Homeostasis (C)</p> Signup and view all the answers

Which nuclei stimulate eating?

<p>Lateral nucleus (D)</p> Signup and view all the answers

Lesions of what area will result in obesity?

<p>Ventromedial nucleus (D)</p> Signup and view all the answers

What area is the satiety center?

<p>Ventromedial nucleus (C)</p> Signup and view all the answers

Is the anterior pituitary neural in origin?

<p>No (D)</p> Signup and view all the answers

The supraoptic nuclei project to which location?

<p>Posterior pituitary (D)</p> Signup and view all the answers

What two hormones are released by the posterior pituitary?

<p>Oxytocin and vasopressin (D)</p> Signup and view all the answers

Pituitary adenomas may also lead to what kind of visual field loss?

<p>Bitemporal visual field loss (A)</p> Signup and view all the answers

The suprachiasmatic nuclei are concerned with what?

<p>Circadian rhythms (C)</p> Signup and view all the answers

The mammillary bodies project to what part of the thalamus?

<p>Anterior Nucleus (B)</p> Signup and view all the answers

What two neuronal products work as both peripheral hormones and a neurotransmitters?

<p>Oxytocin and vasopressin (A)</p> Signup and view all the answers

Activation of the sympathetic division of the autonomic nervous system is associated with what part of the hypothalamus?

<p>Posterior hypothalamus (A)</p> Signup and view all the answers

What is the anterior-posterior dimension of the arcuate nucleus?

<p>Middle (B)</p> Signup and view all the answers

What system do the medial forebrain bundle connection?

<p>Limbic system (A)</p> Signup and view all the answers

The mammillothalamic tract is part of what circuit?

<p>Papez circuit (B)</p> Signup and view all the answers

From which embryological structure is the cerebral hemisphere derived?

<p>Telencephalon (A)</p> Signup and view all the answers

What type of matter primarily makes up the cerebral cortex?

<p>Gray Matter (C)</p> Signup and view all the answers

What are the ridges on the surface of the cerebral cortex called?

<p>Gyri (D)</p> Signup and view all the answers

What are the furrows on the surface of the cerebral cortex called?

<p>Sulci (C)</p> Signup and view all the answers

What percentage of the cerebral cortex is estimated to be hidden within the depths of the sulci?

<p>70% (D)</p> Signup and view all the answers

What axons beneath the cerebral cortex form an extensive mass of white matter?

<p>Running to and from the cells of the cortex (A)</p> Signup and view all the answers

Which of the following best describes the function of the falx cerebri?

<p>Separates the two cerebral hemispheres (C)</p> Signup and view all the answers

What structure unites the cerebral hemispheres in the depths of the longitudinal fissure?

<p>Corpus callosum (C)</p> Signup and view all the answers

What is the function of the lateral fissure?

<p>Separates the temporal lobe from the frontal and parietal lobes (C)</p> Signup and view all the answers

Which cortical area lies within the depths of the lateral fissure?

<p>Insula (C)</p> Signup and view all the answers

Which lobe primarily constitutes the region in front of the central sulcus?

<p>Frontal lobe (B)</p> Signup and view all the answers

Which area is located most anteriorly in the brain?

<p>Frontal Lobe (D)</p> Signup and view all the answers

Which of the following areas makes up most of the frontal lobe?

<p>Rest of the frontal lobe anterior to the precentral gyrus (C)</p> Signup and view all the answers

Which cortex is the most anterior part of the parietal lobe?

<p>Postcentral cortex (C)</p> Signup and view all the answers

Which sulcus on the medial surface clearly marks the boundary between the parietal and occipital lobes?

<p>Parieto-occipital sulcus (B)</p> Signup and view all the answers

The occipital lobe's primary function is:

<p>Visual cortex (B)</p> Signup and view all the answers

The prominent calcarine sulcus on the medial surface of the occipital lobe indicates

<p>Primary Visual Cortex (A)</p> Signup and view all the answers

What fissure does the temporal lobe lie beneath?

<p>Lateral fissure (D)</p> Signup and view all the answers

What anatomical feature is contained within the superior temporal gyrus?

<p>Primary auditory cortex (A)</p> Signup and view all the answers

Which gyrus curves around the corpus callosum?

<p>Cingulate gyrus (C)</p> Signup and view all the answers

What sulcus separates the cingulate gyrus from the rest of the hemisphere?

<p>Cingulate sulcus (D)</p> Signup and view all the answers

Where is the frontal lobe located in relation to the central sulcus?

<p>Anterior (B)</p> Signup and view all the answers

The precentral gyrus is best referred to as the...

<p>Motor cortex (B)</p> Signup and view all the answers

The precentral gyrus corresponds to:

<p>Brodmann's area 4 (B)</p> Signup and view all the answers

Within the cortex of the precentral gyrus, body is represented in a precise...

<p>Somatotopic fashion (A)</p> Signup and view all the answers

Where is the head area located in the context of representation of parts of the body?

<p>Inferior parts of the precentral gyrus (C)</p> Signup and view all the answers

The body is inverted, with the x area located in the inferior parts of the precentral gyrus, just above the y.

<p>head/lateral fissure (C)</p> Signup and view all the answers

The principal subcortical afferents to the primary motor cortex originate from the VL nucleus of the:

<p>Thalamus (A)</p> Signup and view all the answers

Which anatomical region is immediately anterior to the primary motor cortex?

<p>Premotor cortex (B)</p> Signup and view all the answers

What area lies mediately in front of the premotor cortex?

<p>Supplementary motor area (B)</p> Signup and view all the answers

Giant Betz cells:

<p>Are absent from premotor areas (D)</p> Signup and view all the answers

Unilateral damage to the frontal eye causes conjugate deviation of the eyes towards the side of the x.

<p>Lesion (C)</p> Signup and view all the answers

Where is Broca's Area (motor speech area) typically located in most people?

<p>Left frontal lobe (B)</p> Signup and view all the answers

The extensive regions that lie anterior to the premotor area are referred to as

<p>The prefrontal cortex (B)</p> Signup and view all the answers

What cognitive functions is the prefrontal cortex known to have?

<p>Intellectual, judgmental, and predictive faculties (A)</p> Signup and view all the answers

What lobe is bounded posteriorly and inferiorly by the occipital and temporal lobes?

<p>Parietal (B)</p> Signup and view all the answers

The area of the cortex devoted to a particular body part reflects the richness of x innervation

<p>Sensory (B)</p> Signup and view all the answers

That area of the brain is part of the primary gustatory cortex?

<p>Anterior insula (A)</p> Signup and view all the answers

Within the superior bank of the temporal gyrus.

<p>The lateral fissure (C)</p> Signup and view all the answers

Lesions of the primary visual cortex cause blindness in the corresponding what of the visual field.

<p>part (C)</p> Signup and view all the answers

What best describes the composition of commissural fibers?

<p>run from one cerebral hemisphere to the other (D)</p> Signup and view all the answers

Where does the largest neural input to the hypothalamus originate?

<p>The hippocampus and the amygdala (B)</p> Signup and view all the answers

What type of signals does the circulating blood provide to the hypothalamus?

<p>Physical, chemical, and hormonal (D)</p> Signup and view all the answers

What is the main function of the paraventricular and supraoptic nuclei?

<p>Regulation of water balance, production of ADH and oxytocin. (D)</p> Signup and view all the answers

What main hormone is associated with the suprachiasmatic nucleus?

<p>Melatonin (C)</p> Signup and view all the answers

The hypothalamus is attached to which structure via the infundibulum?

<p>Pituitary Gland (A)</p> Signup and view all the answers

Which of the following is the largest part of the forebrain?

<p>Cerebral hemisphere (A)</p> Signup and view all the answers

Approximately what percentage of the cerebral cortex is hidden within the sulci?

<p>70% (C)</p> Signup and view all the answers

Axons running to and from cells of the cortex form what?

<p>White matter (C)</p> Signup and view all the answers

Which structure unites the cerebral hemispheres?

<p>Corpus callosum (B)</p> Signup and view all the answers

What kind of fibers make up the corpus callosum?

<p>Commissural (C)</p> Signup and view all the answers

What is the deepest cleft on the lateral surface of the hemisphere?

<p>Lateral fissure (D)</p> Signup and view all the answers

Where does the frontal lobe lie in relation to the central sulcus?

<p>Anterior (C)</p> Signup and view all the answers

Name the structure lying immediately anterior and parallel to the central sulcus:

<p>Precentral gyrus (A)</p> Signup and view all the answers

What primary cortex is located in the postcentral gyrus?

<p>Somatosensory cortex (A)</p> Signup and view all the answers

Where does the visual cortex receive fibers from the lateral geniculate nucleus?

<p>Optic radiation (C)</p> Signup and view all the answers

What sulcus prominently indicates the location of the primary visual cortex on the medial surface?

<p>Calcarine sulcus (A)</p> Signup and view all the answers

What area is referred to as the motor speech area?

<p>Broca's area (B)</p> Signup and view all the answers

In most humans, which hemisphere is said to be dominant for language?

<p>Left (B)</p> Signup and view all the answers

The extensive regions of cortex anterior to promotor are called what?

<p>Prefrontal cortex (D)</p> Signup and view all the answers

What part of the brain is closely associated with motor aspects of speech?

<p>Broca's Area (C)</p> Signup and view all the answers

What sulcus extends rostrally and is sometimes termed the rhinal fissure?

<p>Collateral sulcus (D)</p> Signup and view all the answers

The anterior spinal artery arises from which blood vessel(s)?

<p>Two vertebral arteries (C)</p> Signup and view all the answers

Where does the anterior spinal artery descend?

<p>Ventral surface of the spinal cord (D)</p> Signup and view all the answers

The posterior spinal arteries typically arise from which blood vessels?

<p>Vertebral arteries or posterior inferior cerebellar arteries (D)</p> Signup and view all the answers

What surface of the spinal cord do the posterior spinal arteries run caudally on?

<p>Posterolateral surface (A)</p> Signup and view all the answers

What vessels provide serial reinforcement to the anterior and posterior spinal arteries?

<p>Radicular arteries (C)</p> Signup and view all the answers

Through which structures do radicular arteries pass?

<p>Intervertebral foramina (B)</p> Signup and view all the answers

The great radicular artery (artery of Adamkiewicz) typically arises between which vertebral level?

<p>T8-L3 (B)</p> Signup and view all the answers

What anterior and posterior veins run in the midline of the spinal cord?

<p>Spinal veins (D)</p> Signup and view all the answers

Posterolateral veins are located near which structure?

<p>Lines of attachment of the dorsal nerve roots (A)</p> Signup and view all the answers

The ascending lumbar veins and the azygos veins communicate with which venous plexus?

<p>Internal vertebral venous plexus (A)</p> Signup and view all the answers

What area of the spinal cord is most vulnerable to blood supply issues?

<p>Thoracic region (A)</p> Signup and view all the answers

Occlusion of which artery leads to paraplegia and incontinence?

<p>Anterior spinal artery (C)</p> Signup and view all the answers

Which sensory modalities are preferentially lost with occlusion of the anterior spinal cord?

<p>Pain and temperature (C)</p> Signup and view all the answers

Which arteries primarily supply the brain with blood?

<p>Internal carotid and vertebral arteries (D)</p> Signup and view all the answers

Where does the internal carotid artery enter the cranial cavity?

<p>Carotid canal (B)</p> Signup and view all the answers

What structures are supplied by the internal carotid arteries and their branches?

<p>Cerebral hemispheres, basal ganglia, eyes, nose, nasal cavity, and paranasal sinuses (D)</p> Signup and view all the answers

Where does the internal carotid artery bifurcate into its two terminal branches?

<p>Carotid bifurcation (A)</p> Signup and view all the answers

The internal carotid artery is found within which area of the neck?

<p>Carotid triangle (A)</p> Signup and view all the answers

The cervical part of the internal carotid artery travels with the internal jugular vein and the...

<p>Vagus nerve (A)</p> Signup and view all the answers

Which structure does the petrous part of the internal carotid artery cross without passing through it?

Signup and view all the answers

Which artery passes from the carotid canal to the tympanic cavity?

<p>Caroticotympanic artery (B)</p> Signup and view all the answers

In what sinus does the cavernous part of the internal carotid artery pass through?

<p>Cavernous sinus (B)</p> Signup and view all the answers

What is the curve of the cavernous part of the internal carotid artery known as?

<p>Carotid siphon (B)</p> Signup and view all the answers

Which cranial nerves run through the cavernous sinus, lateral to the internal carotid artery?

<p>Oculomotor, trochlear, ophthalmic, maxillary, and abducens nerves (D)</p> Signup and view all the answers

Which arteries supply the neurohypophysis?

<p>Inferior hypophyseal arteries (B)</p> Signup and view all the answers

The superior hypophyseal artery arises from which blood vessel?

<p>Internal carotid artery (B)</p> Signup and view all the answers

The final portion of the internal carotid artery is considered the...

<p>Intracranial or supraclinoid part (D)</p> Signup and view all the answers

After leaving the cavernous sinus, the internal carotid artery travels between which structures?

<p>Optic and oculomotor nerves (D)</p> Signup and view all the answers

Into what two terminal branches does the internal carotid artery bifurcate?

<p>Anterior and middle cerebral arteries (D)</p> Signup and view all the answers

Where does the ophthalmic artery originate?

<p>After the internal carotid pierces through the dura mater (A)</p> Signup and view all the answers

With what structure does the ophthalmic artery enter the optic canal?

<p>Optic nerve (D)</p> Signup and view all the answers

What circulation systems of the brain does the PCA connect?

<p>Anterior and posterior (C)</p> Signup and view all the answers

Which artery supplies the brain?

<p>Middle cerebral artery (E)</p> Signup and view all the answers

The ACA, supplies medial aspects of what lobes?

<p>Frontal and parietal (B)</p> Signup and view all the answers

What arteries are known as being long striate arteries?

<p>Central Branches (A)</p> Signup and view all the answers

What structures does the middle cerebral artery supply?

<p>Subcortical and cortical regions of the cerebral hemispheres (C)</p> Signup and view all the answers

What artery supplies and ascends posteiorly on the insula?

<p>Middle cerebral artery (D)</p> Signup and view all the answers

The middle cerebral artery includes what type of cortical branches?

<p>Orbital, frontal, parietal and temporal (C)</p> Signup and view all the answers

The temporal branches of the middle cerebral artery are distributed where?

<p>Lateral surface to the temporal lobe (A)</p> Signup and view all the answers

The anterior cerebral artery is supplied by what limb territories?

<p>Lower limb (D)</p> Signup and view all the answers

The vertebral artery provides arterial blood supply to which of the following?

<p>All of the above (D)</p> Signup and view all the answers

The vertebral artery is usually subdivided into how many segments?

<p>4 (D)</p> Signup and view all the answers

The vertebral arteries spinal branches supply what structure?

<p>Spinal cord via the intervertebral foramine (B)</p> Signup and view all the answers

Which artery arises in a Y-shaped configuration from the two vertebral arteries?

<p>Anterior Spinal Artery (D)</p> Signup and view all the answers

Which arteries run caudally on the posterolateral surface of the spinal cord?

<p>Posterior Spinal Arteries (D)</p> Signup and view all the answers

The radicular arteries pass through which structure?

<p>Intervertebral Foramina (D)</p> Signup and view all the answers

Into what do all vessels of both anterior and posterior radicular veins drain?

<p>Internal vertebral venous plexus (B)</p> Signup and view all the answers

The internal vertebral venous plexus communicates with which veins?

<p>Azygos and ascending lumbar veins (A)</p> Signup and view all the answers

Which artery supplies arterial blood to structures found within the skull, such as the cerebral hemispheres and basal ganglia?

<p>Internal Carotid Artery (A)</p> Signup and view all the answers

The vertebral arteries unite to form what artery?

<p>Basilar Artery (C)</p> Signup and view all the answers

Which artery is encased and surrounded by small veins and the superior cervical ganglion's branches, which form the carotid plexus?

<p>Petrous part (D)</p> Signup and view all the answers

Which of the following arteries are connected by the posterior communicating arteries to form the Circle of Willis?

<p>Internal Carotid and Vertebral arteries (D)</p> Signup and view all the answers

Blockage or rupture of vessels in the cerebral circulation primarily results in what condition?

<p>Stroke (A)</p> Signup and view all the answers

Flashcards

Nervous Tissue

Tissue type specialized for electrical and chemical signaling throughout the body.

Neurons

Cells that transmit electrical signals and are the functional units of the nervous system.

Glia

Support cells in the nervous system that provide structural and metabolic support to neurons.

Multipolar Neuron

Neuron with one axon and multiple dendrites, most common type.

Signup and view all the flashcards

Bipolar Neuron

Neuron with one axon and one dendrite.

Signup and view all the flashcards

Pseudounipolar Neuron

Neuron with a single process that splits into two branches, acting as one long axon.

Signup and view all the flashcards

Axon Hillock

The cone-shaped region of a neuron's axon where it joins the cell body.

Signup and view all the flashcards

Dendrites

Branchlike extensions of a neuron that receive signals from other neurons.

Signup and view all the flashcards

Soma

The cell body of a neuron, containing the nucleus and other organelles.

Signup and view all the flashcards

Axon

The extension of a neuron that carries signals away from the cell body.

Signup and view all the flashcards

Myelin

Insulating layer around nerve fibers.

Signup and view all the flashcards

Node of Ranvier

Gaps in the myelin sheath where the axon is exposed.

Signup and view all the flashcards

Oligodendrocytes

A type of glial cell that forms myelin in the central nervous system.

Signup and view all the flashcards

Schwann Cell

A type of glial cell that forms myelin in the peripheral nervous system.

Signup and view all the flashcards

Ependymal cells

Cell forming the lining of brain ventricles and spinal cord central canal.

Signup and view all the flashcards

Choroid Plexus

A specialized structure in the brain ventricles that produces cerebrospinal fluid.

Signup and view all the flashcards

Peripheral Nerves

Bundles of axons in the peripheral nervous system.

Signup and view all the flashcards

Epineurium

A connective tissue sheath that surrounds the entire peripheral nerve.

Signup and view all the flashcards

Perineurium

Connective tissue that surrounds fascicles (bundles) of axons in a nerve.

Signup and view all the flashcards

Endoneurium

Connective tissue that surrounds individual axons within a nerve.

Signup and view all the flashcards

Ganglia

A collection of neuron cell bodies located outside the central nervous system.

Signup and view all the flashcards

Satellite Cells

Type of glial cell found in sensory ganglia that supports neuron cell bodies.

Signup and view all the flashcards

Autonomic Nervous System

Division of the nervous system controlling automatic bodily functions.

Signup and view all the flashcards

Sympathetic Nervous System

Part of the autonomic nervous system that prepares the body for stress.

Signup and view all the flashcards

Parasympathetic Nervous System

Nervous system division that promotes rest, digestion and energy conservation.

Signup and view all the flashcards

Neuron

Neuron consists of cell body, dendrites, and axon.

Signup and view all the flashcards

Synapse

Specialized contact points between neurons for communication.

Signup and view all the flashcards

Nissl Bodies

Clusters of ribosomes in neurons, sites of protein synthesis.

Signup and view all the flashcards

Neuron Cell Body

Contains the same organelles found in all animal cells.

Signup and view all the flashcards

Rough ER

Enclosed stacks of membrane dotted with ribosomes measuring about 25 nm in diameter.

Signup and view all the flashcards

Rough ER

Major site of protein synthesis where transcripts are bound to ribosomes and translated to assemble a protein molecule.

Signup and view all the flashcards

Golgi Apparatus

Stack of membrane farthest from the nucleus, processing, sorting and packaging proteins.

Signup and view all the flashcards

Neuronal Membrane

Neuronal membrane serves as a barrier to close the cytoplasm and to exclude some of the substances floating in the fluid that bathes the neuron.

Signup and view all the flashcards

Dendrites

The part of neuron resembles like the branches of a tree as they extend from the soma.

Signup and view all the flashcards

Dendritic Spines

Appendages on dendrites that receive some types of synaptic input

Signup and view all the flashcards

Dendrite Cytoplasm

The cytoplasm of dendrites resembles axons and is filled with cytoskeletal elements and mitochondria.

Signup and view all the flashcards

Axon

Neuron projection specialized to transmit information to other neurons or effector cells.

Signup and view all the flashcards

Axon Hillock

Tapered region where the axon emerges from the cell body.

Signup and view all the flashcards

Cytoskeleton

The supporting framework composed of microtubules, neurofilaments, and microfilaments.

Signup and view all the flashcards

Actin Filaments

Slender protein strands, 7 nm in diameter, maintains cell shape, cell motility.

Signup and view all the flashcards

Intermediate Filaments

Fibers wound into the thicker cables, maintains cell shape, anchor nucleus.

Signup and view all the flashcards

Microtubules

Hollow tubular structure, maintains cell shape, moves and transfers chromosomes.

Signup and view all the flashcards

Axoplasmic Transport

Process of moving materials in the axon, essential for neuronal function and maintenance.

Signup and view all the flashcards

Synaptic Vesicles

Membrane bounded structures ranging from 30 to 100 nm in diameter and contain neurotransmitters.

Signup and view all the flashcards

Synapses

Specialized locations allowing the transmission of electrical or chemical signals.

Signup and view all the flashcards

Glial Cells

Support cells in the nervous system; include astrocytes, oligodendrocytes, microglia, and ependymal cells.

Signup and view all the flashcards

Astrocytes

Star-shaped glial cells in the brain and spinal cord, providing structural and metabolic support.

Signup and view all the flashcards

Blood Brain Barrier (BBB)

Regulates passage of substances into the brain, maintaining a stable environment.

Signup and view all the flashcards

Ependyma

Cells lining brain ventricles and the central canal, producing cerebrospinal fluid.

Signup and view all the flashcards

Microglia

Glial cells that remove debris and pathogens.

Signup and view all the flashcards

Fibrous Astrocytes

Long, thin astrocytes which have limited processes and contact axons/Nodes of Ranvier.

Signup and view all the flashcards

Protoplasmic Astrocytes

Short, thick and highly branched astrocytes which envelop nerve cell bodies and synapses.

Signup and view all the flashcards

GFAP (glial fibrillary acidic protein)

Glial filaments found in large numbers in astrocytes.

Signup and view all the flashcards

What do astrocytes contain?

Lysosomes, mitochondria and isolated cisternae of the rough ER

Signup and view all the flashcards

Homeostasis role of Astrocytes

Protects the brain from ionic fluctuations and maintains pH constant.

Signup and view all the flashcards

What do astrocytes form?

Network of cells to communicate with neurons.

Signup and view all the flashcards

What has regional differences in astrocytes?

The expression of connexins.

Signup and view all the flashcards

Pericytes

Cells surrounding capillaries and control vascular function.

Signup and view all the flashcards

Why is the brain a privileged site?

The brain is shielded from systemic circulation.

Signup and view all the flashcards

What are functions of the BBB?

Supplies nutrients, mediates efflux of waste, restricts ion movement.

Signup and view all the flashcards

Function of brain endothelial cells?

Form a continuous sheet covering the surface of capillaries providing a tight seal.

Signup and view all the flashcards

Tight Junctions

Structure of cells lining capillaries, acting like a gatekeeper.

Signup and view all the flashcards

What are three BBB transcellular pathways?

Aqueous, Transport, and Receptor-mediated pathways.

Signup and view all the flashcards

What is Ependyma?

Is a monolayer of cilindric cells that lines the ventricles and central canal.

Signup and view all the flashcards

What is on the Apical membrane of Common Ependyma?

Cilia, microvilli, and mitochondria.

Signup and view all the flashcards

What is purpose of the Choroid plexus?

The main source of CSF that protects the brain and spinal cord.

Signup and view all the flashcards

Location of the Spinal Cord

The spinal cord lies within the vertebral canal and is continuous with the medulla oblongata.

Signup and view all the flashcards

Spinal Cord Function

The spinal cord carries afferent and efferent nerve fibers connecting structures to the periphery.

Signup and view all the flashcards

Spinal Nerve Roots

Spinal nerves divide into dorsal and ventral roots that attach to the cord.

Signup and view all the flashcards

Dorsal Root Function

Dorsal roots carry afferent axons, with cell bodies in dorsal root ganglia (PNS neurons).

Signup and view all the flashcards

Ventral Root Function

Ventral roots carry efferent axons with cell bodies in the spinal gray matter (CNS neurons).

Signup and view all the flashcards

Spinal Cord Termination

In adults, the spinal cord ends at the level of the L1-L2 intervertebral disc.

Signup and view all the flashcards

Cauda Equina

The lumbar and sacral spinal nerves descend as the cauda equina.

Signup and view all the flashcards

Intervertebral Foramina

Spinal nerves exit the vertebral canal through intervertebral foramina.

Signup and view all the flashcards

Central Canal

The spinal cord has a cylindrical shape and contains a central canal.

Signup and view all the flashcards

Gray Matter Shape

The ‘H’ or ‘butterfly’ shape in the spinal cord is due to the separation of cell bodies from nerve fibers.

Signup and view all the flashcards

Dorsal Horn Function

Dorsal horns terminate many afferent neurons conveying sensory impulses.

Signup and view all the flashcards

Ventral Horn Function

Ventral horn contains motor neurons innervating skeletal muscle.

Signup and view all the flashcards

Lateral Horn Location

At thoracic and upper lumbar levels, the lateral horn contains preganglionic neurons (sympathetic nervous system).

Signup and view all the flashcards

Ascending Tracts Definition

Ascending tracts carry information from the trunk and limbs to the brain.

Signup and view all the flashcards

Ascending Tract Types

The major ascending tracts carry fine touch, proprioception, pain, temperature, and information from muscle/joint receptors.

Signup and view all the flashcards

Descending Tracts

Descending tracts control the spinal cord neurons from the brain.

Signup and view all the flashcards

Lateral Corticospinal Tract

The lateral corticospinal tract controls skilled voluntary movement.

Signup and view all the flashcards

Brainstem Components

The brainstem consists of the medulla oblongata, pons, and midbrain.

Signup and view all the flashcards

Cranial Nerve Location

The brainstem contains the origin and termination sites of cranial nerves.

Signup and view all the flashcards

Brainstem Vital Functions

The brainstem hosts centers controlling vital functions such as breathing, circulation, and consciousness.

Signup and view all the flashcards

Medulla Location

The medulla oblongata is continuous with the spinal cord and extends to the pons.

Signup and view all the flashcards

Pons Features

The pons contains fibers that cross the midline.

Signup and view all the flashcards

Fourth Ventricle Location

In midsagittal section, the fourth ventricle sits between the pons/medulla and the cerebellum.

Signup and view all the flashcards

Mesencephalon Structure

The mesencephalon consists of the tegmentum and tectum.

Signup and view all the flashcards

Cranial Nerves Function

Cranial nerves facilitate brainstem receipt of sensory information and control of head/neck activities.

Signup and view all the flashcards

Cranial Nerve Number

There are 12 pairs of cranial nerves.

Signup and view all the flashcards

Attachment of CNs

First two cranial nerves attach to the forebrain, ten others attach to the brainstem.

Signup and view all the flashcards

Cranial Nerve Nuclei location

Cranial nerve nuclei are the origin of motor and termination of sensory fibers.

Signup and view all the flashcards

Cerebellum Location

The cerebellum is located dorsal to the brainstem.

Signup and view all the flashcards

Tentorium Cerebelli

The tentorium cerebelli separates the cerebellum and the posterior cerebral hemispheres.

Signup and view all the flashcards

Cerebellar Peduncles

The cerebellum attaches to the brainstem via cerebellar peduncles.

Signup and view all the flashcards

Cerebellum Structure

The cerebellum consists of gray matter (cerebellar cortex) surrounding a white matter core.

Signup and view all the flashcards

Cerebellum Function

The cerebellum coordinates movement, including eye movements, at an unconscious level.

Signup and view all the flashcards

Midbrain

Rostral to the pons lies the midbrain, dorsal surface has superior and inferior colliculi.

Signup and view all the flashcards

Forebrain

The forebrain consists of the diencephalon and the cerebral hemispheres.

Signup and view all the flashcards

Diencephalon

The two sides of the diencephalon are separated by the third ventricle.

Signup and view all the flashcards

Diencephalon subdivisions

In a dorsoventral direction, diencephalon consists of epithalamus, thalamus, subthalamus and hypothalamus.

Signup and view all the flashcards

Epithalamus components

The epithalamus contains the habenula and pineal gland.

Signup and view all the flashcards

Thalamus Walls definition

The thalamus forms much of the lateral wall of the third ventricle.

Signup and view all the flashcards

Thalamus Functions

The thalamus is important for sensory, motor and cognitive functions.

Signup and view all the flashcards

Subthalamus role

The subthalamus is functionally related to the basal ganglia.

Signup and view all the flashcards

Hypothalamus Location

The hypothalamus forms the lower walls/floor of the third ventricle.

Signup and view all the flashcards

Domination of Brain function

The brain is dominated by the cerebral hemispheres.

Signup and view all the flashcards

Cerebral Hemispheres Composition

The cerebral hemispheres have a convoluted outer mantle of grey matter and inner core of white matter.

Signup and view all the flashcards

Grey matter composition

There is a highly convoluted outer mantle for grey matter

Signup and view all the flashcards

Sulci definition

The cerebral cortex is highly convoluted. The grooves are called sulci .

Signup and view all the flashcards

What is occupied by the fissure?

The fissure normally occupied by the falx cerebri and in its depths lies the corpus callosum.

Signup and view all the flashcards

Lateral Fissure Landmark

The lateral fissure, a deep cleft, is an important landmark on the lateral surface.

Signup and view all the flashcards

Peripheral Nerves Function

The route through which the brain and spinal cord communicate with the rest of the body.

Signup and view all the flashcards

Typical Peripheral Nerve

Numerous nerve fibers, either afferent or efferent.

Signup and view all the flashcards

Peripheral Nerve Fibers

Myelinated or unmyelinated, arranged in bundles surrounded by sheaths of connective tissue.

Signup and view all the flashcards

Nerve Sheath Function

Provides strength and support for the nerve.

Signup and view all the flashcards

Cranial and Spinal Meninges

Continuous with connective tissue sheaths of spinal and cranial nerves.

Signup and view all the flashcards

Pia Mater and Endoneurium

Continuous structural relationship between meninges and nerve sheaths

Signup and view all the flashcards

Arachnoid and Perineurium

Continuous structural relationship between meninges and nerve sheaths

Signup and view all the flashcards

Dura Mater and Epineurium

Continuous structural relationship between meninges and nerve sheaths

Signup and view all the flashcards

Wallerian degeneration

Distal portion degenerates and dies.

Signup and view all the flashcards

Severed Nerve Proximal Portion

Proximal portion may survive and regenerate.

Signup and view all the flashcards

Distal Transection

Cell body survival likelihood increases.

Signup and view all the flashcards

Nissl Granules Degeneration Signs

Dispersal and loss of staining of Nissl granules (chromatolysis).

Signup and view all the flashcards

Cell Body Degeneration Signs

Swelling of cell body.

Signup and view all the flashcards

Nucleus Degeneration Signs

Movement of nucleus to a peripheral location.

Signup and view all the flashcards

Regenerating Nerve Fibers

Re-enter endoneurial tubes and grow at 1-2 mm/day.

Signup and view all the flashcards

Degenerative Processes

Essentially similar in CNS and PNS.

Signup and view all the flashcards

CNS Re-establishment

Does not occur to any significant extent.

Signup and view all the flashcards

Sensorimotor Neuropathies

Muscle weakness, wasting, distal areflexia, sensory loss.

Signup and view all the flashcards

Peripheral Neuropathy Causes

Systemic, vascular, hereditary, infection, immune, paraneoplastic.

Signup and view all the flashcards

Pathological Types of Neuropathies

Demyelinating and axonal.

Signup and view all the flashcards

Spinal Nerve Fibers

Become redistributed to form individual peripheral nerves.

Signup and view all the flashcards

Peripheral Nerve Distribution

Different from that of spinal nerves.

Signup and view all the flashcards

Dermatome

Sensory innervation area of a spinal nerve

Signup and view all the flashcards

Myotome

Muscles innervated by motor component of spinal nerve.

Signup and view all the flashcards

Peripheral Nervous System (PNS)

nerve endings, peripheral nerve trunks, plexuses and ganglia

Signup and view all the flashcards

Plexuses

Structures where fibers redistribute in spinal and cranial nerves.

Signup and view all the flashcards

Peripheral Ganglia

Structures outside the CNS where nerve cell bodies are located.

Signup and view all the flashcards

Nerve Endings Include

Detect changes in internal/external environments; control muscle contraction/gland activity

Signup and view all the flashcards

Afferent Nerve Stimuli

Mechanical, thermal, chemical.

Signup and view all the flashcards

Nerve Fiber Function

Conduct action potentials to the CNS.

Signup and view all the flashcards

Efferent Nerve Endings

Innervate muscle or secretory cells.

Signup and view all the flashcards

Motor nerve endings

Induce movement.

Signup and view all the flashcards

Secretomotor Nerve Endings

Induce cellular secretion.

Signup and view all the flashcards

Types of Sensory Systems

general and special

Signup and view all the flashcards

Exteroceptors Respond To.

nociceptive, temperature, touch, pressure

Signup and view all the flashcards

Proprioceptors Senses

posture and movement (kinesthesia)

Signup and view all the flashcards

Interoceptors are Sensitive To

mechanical and chemical stimuli

Signup and view all the flashcards

Stimulus Characteristics

modality, intensity, duration, location.

Signup and view all the flashcards

Generator Potential

Across membrane leading to an action potential.

Signup and view all the flashcards

Combine the Stimulus

Combine characteristics into a perceived sensation

Signup and view all the flashcards

Slowly Adapting Receptors

Respond continuously to a sustained stimulus.

Signup and view all the flashcards

Rapidly Adapting Receptors

Respond to any dynamic change in the receptor.

Signup and view all the flashcards

Peripheral receptors Classified.

Morphology, location, stimulus type.

Signup and view all the flashcards

Cutaneous Receptors Subserve

Touch, pressure, vibration, temperature, nociception.

Signup and view all the flashcards

Special Senses

Special senses carried by cranial nerves, including olfaction, vision, taste, hearing, and vestibular function.

Signup and view all the flashcards

General Senses

Modalities like touch, pressure, pain, temperature, awareness of posture and movement.

Signup and view all the flashcards

Pain and temperature

Relays pain/temperature info from skin (exteroceptors) and viscera (interoceptors).

Signup and view all the flashcards

Proprioception

Awareness of body position and movement derived from joints, tendons, muscles.

Signup and view all the flashcards

Spinal Nerves

General sensory information from the trunk and limbs carried in these nerves.

Signup and view all the flashcards

Trigeminal Nerve

Nerve carrying general sensory information from the head.

Signup and view all the flashcards

General Sensation Pathway

The sequence of three neurons from sensory receptor to the cerebral cortex

Signup and view all the flashcards

Primary Afferent Neuron

Enters the spinal cord/brainstem via spinal or trigeminal nerve on the same side as the receptor.

Signup and view all the flashcards

Second-Order Neuron

Neuron with cell body in spinal cord/brainstem that crosses to the other side of CNS then ascends to the Thalamus.

Signup and view all the flashcards

Third-Order Neuron

Neuron with cell body in thalamus, projects to somatosensory cortex.

Signup and view all the flashcards

Anterolateral System

System for sensing coarse touch, pain, and temperature, spinal afferents terminate near the entry point.

Signup and view all the flashcards

Spinothalamic Tract

Sensory discriminative pathway for pain/temperature that projects to the ventral posterior lateral nucleus.

Signup and view all the flashcards

Ventral Posterior Lateral (VPL) nucleus

Thalamic nucleus receiving sensory-discriminative input relates to pain. Projects to somatic sensory cortex.

Signup and view all the flashcards

Dorsal Column-Medial Lemniscus Pathway

Pathway for fine touch and proprioception.

Signup and view all the flashcards

Dorsal Column Nuclei

Located in medulla oblongata, these receive axons from fasciculi gracilis/cuneatus for fine touch, proprioception.

Signup and view all the flashcards

Medial Lemniscus

A fiber tract formed from second-order neurons ascending to the thalamus

Signup and view all the flashcards

Trigeminothalamic Tract

Carries proprioception, touch, nociception; fibers from cranial nerve V terminate ipsilaterally.

Signup and view all the flashcards

Thalamocortical Fibers

Axons project to the somatosensory cortex in the post-central gyrus of the parietal lobe.

Signup and view all the flashcards

Somatotopic Organization

The sensory area occupies a strip from medial (leg) to inferolateral (head) aspect of the parietal lobe.

Signup and view all the flashcards

Lower Motor Neurons

Neurons that directly innervate skeletal muscles, cell bodies in the gray matter of spinal cord or brainstem.

Signup and view all the flashcards

Spinal Cord

A structure of great importance that includes its paired spinal nerves, which Receive afferent fibers, control movements, and provide autonomic innervation.

Signup and view all the flashcards

Vertebral Spinal Canal

The spinal cord resides within the vertebral canal, providing it support and protection.

Signup and view all the flashcards

Medulla Oblongata

The spinal cord is continuous with the medulla oblongata, which is the structure at the top of the spinal cord.

Signup and view all the flashcards

Spinal Cord Subdivisions

8 (C)*, 12 thoracic (T), 5 lumbar (L), 5 sacral (S) and 1 coccygeal segments form this arrangement; it is a segmental structure.

Signup and view all the flashcards

Cervical Enlargement

The enlargement of cord segments C4-T1 offers innervation for the upper limb.

Signup and view all the flashcards

Lumbar Enlargement

The enlargement of cord segments L1-S3 provides the lower limb's innervation

Signup and view all the flashcards

Conus Medullaris

The cord tapers off after the lumbar enlargement to form this conelike structure.

Signup and view all the flashcards

Filum Terminale

A strand of connective tissue between L1 and L2 that supports the spinal cord.

Signup and view all the flashcards

Spinal Nerve Trajectory

The dorsal and ventral roots follow an oblique path to reach their respective intervertebral foramina.

Signup and view all the flashcards

Dorsal and Ventral Rami

Spinal nerves which divide into a dorsal ramus and much larger ventral ramus.

Signup and view all the flashcards

Dorsal Ramus

The muscles and skin of the back region are supplied by this anatomical structure.

Signup and view all the flashcards

Ventral Ramus

The ventral ramus supplies the muscles and skin of the front of the body and the limbs.

Signup and view all the flashcards

Dorsal Roots

These roots of the spinal nerves carry afferent axons from the periphery of the body to the brain.

Signup and view all the flashcards

Dorsal Root Ganglia (DRG)

The structure containing the cell bodies of sensory neurons.

Signup and view all the flashcards

Ventral Roots

These roots of the spinal nerves carry efferent axons from the brain to the periphery of the body.

Signup and view all the flashcards

The C1 Spinal Nerve

Spinal nerve that has a ventral root containing motor fibers but no dorsal root.

Signup and view all the flashcards

Dorsal Horn

Name for the lamina region of the spinal cord where many afferent fibers entering in the dorsal root terminate

Signup and view all the flashcards

Ventral Horn

Name for the lamina region of the spinal cord contains the cell bodies of motor neurons whose axons exit through the ventral nerve.

Signup and view all the flashcards

Lateral Horn

A minor structure at thoracic and upper lumbar segments between the the dorsal and ventral horns, containing preganglionic sympathetic neurons.

Signup and view all the flashcards

White Matter

The outer region of the core is comprised of this matter that contains bundles of axons

Signup and view all the flashcards

Grey Matter

The middle area surrounding the ventral canal is comprised of this matter that consists of nerve cell bodies, their dendrites, and synaptic contacts

Signup and view all the flashcards

Joining Fibers

These fibers integrate function to neighbouring and distant cord segments.

Signup and view all the flashcards

Rexed's Laminae

Tract where Rexed's Laminae are numbered sequentially from dorsal to ventral and the basis of the cytoarchitecture of the gray matter.

Signup and view all the flashcards

Lamina I (Marginal Zone)

Neuron cell bodies that intermingle with fibers; relay pain and temperature.

Signup and view all the flashcards

Lamina II

Substantia Gelatinosa; interneurons receiving sensory information; pain and temperature.

Signup and view all the flashcards

Laminae III & IV

Laminae that are similar and referred to as nucleus proprius; contains second-order neurons.

Signup and view all the flashcards

Lamina V

Neck of the dorsal horn and contains projection neurons that are the targets of visceral referred pain

Signup and view all the flashcards

Lamina VI

A porprioceptive lamina at the base of the dorsal horn and only evident in cervical and lumbosacral enlargements.

Signup and view all the flashcards

Lamina VII

Most of the intermediate region of the gray matter. and includes the lateral horn/autonomic nervous system.

Signup and view all the flashcards

Lamina VIII

Found in the ventral horn, receives inputs from descending tracts.

Signup and view all the flashcards

Lamina IX

Found in the ventral horn and consists of motoneurons that innervate the skeletal muscle.

Signup and view all the flashcards

Lamina X

The Lamina that Forms the commissural area between the two halves of the grey matter and surrounds the central canal.

Signup and view all the flashcards

Interneurons

Neurons that modify information and form circuitry to link sensory fibers; excitatory or inhibitory.

Signup and view all the flashcards

Spinal Interneurons

Term for cord interneurons receiving inputs from other sources such as descending fibers from higher centers.

Signup and view all the flashcards

Lissauer's Tract

Afferent fibers through the dorsal roots that synapse with substantia gelatinosa

Signup and view all the flashcards

The Dorsal Horn

Where dorsal root fibers terminate extensively through the grey matter.

Signup and view all the flashcards

Substantia Gelatinosa

The area where region receives collaterals of smallest diameter myelinated afferents

Signup and view all the flashcards

Nociception Control

Gate control theory. Tactile info inhibits nociception.

Signup and view all the flashcards

Clarke's Column

Contains a number of important cell groups; Input from muscle spindles and golgi tendon organs.

Signup and view all the flashcards

Skeletal Muscle

Muscle of type that is innervated by motor neurons, which corresponds to clusters of motor neurons that innervate said tissues.

Signup and view all the flashcards

Alpha Motor Neurons to...

In ventral horn, lamina IX innervates types of these muscles

Signup and view all the flashcards

Motor Neurons

General, motor neurons innervate axial musculature

Signup and view all the flashcards

Direct Input

Is what cells in the ventral horn recieve from dorsal root afferents

Signup and view all the flashcards

The Stretch Reflex

When a muscle stretches, is responds by contracting

Signup and view all the flashcards

Muscles Stretch

Muscle's stretch receptors, called intrafusal muscle fibers

Signup and view all the flashcards

Rapid Dynamic Function

Deep tendon reflexes or jumps resulting from muscle contraction elicited from tapping the tendon with a reflex

Signup and view all the flashcards

Cerebellum

Largest part of the hindbrain, dorsal to the brainstem, overlying the fourth ventricle.

Signup and view all the flashcards

Peduncle Connections

Connects cerebellum to medulla oblongata (inferior), pons (middle), midbrain (superior).

Signup and view all the flashcards

Superior Peduncle Function

Superior cerebellar peduncle; efferent axons.

Signup and view all the flashcards

Middle Peduncle Function

Middle cerebellar peduncle; afferent axons.

Signup and view all the flashcards

Inferior Peduncle Function

Inferior cerebellar peduncle; both afferent and efferent axons.

Signup and view all the flashcards

Cerebellar Folia

Cerebellum's surface folds oriented transversely.

Signup and view all the flashcards

Landmark Fissures

Divides cerebellum into three lobes

Signup and view all the flashcards

Primary Fissure

Separates anterior and posterior lobes

Signup and view all the flashcards

Cerebellar Cortex

Outer layer of gray matter.

Signup and view all the flashcards

Cerebellar White Matter

Inner core of white matter.

Signup and view all the flashcards

Arbor Vitae

White matter formation resembling a tree.

Signup and view all the flashcards

Cerebellar Nuclei

Deep structures in the cerebellar WM.

Signup and view all the flashcards

Cerebellar Nuclei

Four pairs, output of cerebellum.

Signup and view all the flashcards

Inferior Vermis

Transverse groove between hemispheres.

Signup and view all the flashcards

Dentate Nucleus

Largest cerebellar nuclei.

Signup and view all the flashcards

Cerebellar Layers

Outer and inner layers of gray matter

Signup and view all the flashcards

Spinocerebellar Tracts

Carry subconscious sensory info.

Signup and view all the flashcards

Spinocerebellar Fibers

Carry information to a subconscious level derived from muscle spindles.

Signup and view all the flashcards

Dorsal spinocerebellar Tract

Muscle spindle in trunk and lower limb

Signup and view all the flashcards

Ventral spinocerebellar tract

A group of axons, primarily from the Golgi tendon organs

Signup and view all the flashcards

Cuneocerebellar Tract

Axons from the muscle spindles terminate just behind cuneate nucleus

Signup and view all the flashcards

Afferent Projections

They terminate as climbing fibers in the molecular layer of the contralateral cortex

Signup and view all the flashcards

Pontocerebellar fibers

Arise from Pons and terminate in lateral regions of anterior and posterior lobe

Signup and view all the flashcards

Cerebellar cortex layers

Consist of outer fiber-rich with molecular layer.

Signup and view all the flashcards

Rostral fastigial nucleus (rFN)

Receives inputs from Purkinje cells and involved with the vestibular system; interpret body movement.

Signup and view all the flashcards

Caudal fastigial nucleus (cFN)

Receives input from Purkinje cells of the oculomotor vermis and controls saccadic eye movements.

Signup and view all the flashcards

Dynamic ataxia

Impair the limb motility.

Signup and view all the flashcards

Prosencephalon (Forebrain)

Brain region that includes the diencephalon and cerebral hemispheres.

Signup and view all the flashcards

Epithalamus

Relatively small part of the diencephalon; includes the pineal gland and habenula.

Signup and view all the flashcards

Habenula

A pair of small nuclei located above the thalamus Involved in the limbic system and projects to the brainstem and hypothalamus.

Signup and view all the flashcards

Stria Medullaris

Fiber bundle visible on the dorsal surface of the thalamus, axons projecting to the Habenula.

Signup and view all the flashcards

Pineal Gland

Endocrine organ; synthesizes melatonin and delays puberty.

Signup and view all the flashcards

Subthalamic nucleus

Plays a vital role in controlling movement and has connections with globus pallidus and the substantia nigra.

Signup and view all the flashcards

Zona Incerta

Rostral extension of the brainstem reticular formation which integrates sensory challenges for motor control.

Signup and view all the flashcards

Subthalamus

Lies beneath the Thalamus and controls movement.

Signup and view all the flashcards

Diencephalon Location

Continuous with midbrain, lies between brainstem and cerebral hemisphere.

Signup and view all the flashcards

Infundibulum

Extends from tuber cinereum, attaches to the pituitary gland.

Signup and view all the flashcards

Mammillary Bodies

Pair of rounded eminences caudal to the tuber cinereum that are located on either side of the midline.

Signup and view all the flashcards

Habenular Nuclei Pathway

Links septum, hypothalamus & monoaminergic brainstem nuclei.

Signup and view all the flashcards

Thalamus

Largest component of diencephalon; relay site for all sensory pathways (except olfaction) to cerebral cortex.

Signup and view all the flashcards

Hypothalamic Sulcus

Groove marking transition between thalamus and hypothalamus.

Signup and view all the flashcards

Massa Intermedia

Connects the two thalami across the third ventricle.

Signup and view all the flashcards

Stria Terminalis

Connects amygdala with bed nucleus, regulates glucose, appetite.

Signup and view all the flashcards

Thalamic Nuclei

Conducts sensory information to neocortex.

Signup and view all the flashcards

Thalamic Nuclei

Consists of axons that transmit general and special sensory information to corresponding regions of the sensory cortex.

Signup and view all the flashcards

Thalamic Nuclei

Consists of nuclei that receive impulses from the Cerebellum and basal ganglia and interface with motor regions of the frontal lobe.

Signup and view all the flashcards

Thalamic Nuclei

Consists of nuclei that have associations with associative and limbic areas of the cerebral cortex.

Signup and view all the flashcards

Internal Medullary Lamina (IML)

Bundle that divides the thalamus into three different regions.

Signup and view all the flashcards

Thalamocortical Connections

Specific thalamic connections under the general and special senses.

Signup and view all the flashcards

Relay Nuclei

Receives well-defined inputs and projects this signal to functionally distinct areas of the cerebral cortex to relay primary sensations.

Signup and view all the flashcards

Drugs That Potentiate Dopamine

Nuclei that have defects in axons result degeneration and axons from the lateral habenula.

Signup and view all the flashcards

Continuous Nicotine

Nuclei that selectively induces degeneration in axons from the medial habenula to the interpeduncular nucleus.

Signup and view all the flashcards

Metathalamus

Includes nuclei that protrude from the posterior aspect of the pulvinar of the thalamus.

Signup and view all the flashcards

Reticular nucleus of thalamus

The most lateral specific thalamic nuclei that is situated to the other specific thalamic nuclei. Main source of electrical impulses that are recorded in an electroencephalogram.

Signup and view all the flashcards

Medial / Lateral Geniculate Nuclei

Relays vision and hearing respectively.

Signup and view all the flashcards

Reticular Nucleus

Lateral specific thalamic nucleus shown in the diagram is the (blank) of the thalamus, which is situated lateral of the other specific thalamic nuclei.

Signup and view all the flashcards

The VL nucleus

Receives input from the cerebellum, mainly from the dentate nucleus, the is put from the put from the basal ganglia to the rostral part of the VL.

Signup and view all the flashcards

VA nucleus

Most of its input is from the basal ganglia especially the medial globus pallidus and substantia nigra, parks reticulata.

Signup and view all the flashcards

Thalamus General

It is are the primary of relay for all of the sensory pathways except olfaction on their way to the cerebral cortex.

Signup and view all the flashcards

The Association Nuclei

Receives most of their input from the cerebral cortex and project back to the is projected cortex in the association areas to regulate their activity.

Signup and view all the flashcards

Medial Dorsal Nucleus

Receives spinalthalamic input it to the gyrus, which is involved in the emotional aspects of somatic sensory stimulation.

Signup and view all the flashcards

Ventral Lateral Nucleus

The side of the central lateral portion of the body relay is input from the extremities and is that that is the side of the body.

Signup and view all the flashcards

Ventral Intermediate Nucleus

Receives afferent input from the vestibular nuclei concerning the coordination of gays toward the ipsilateral side .

Signup and view all the flashcards

Axons Thalamic Nuclei

Consists of fibers that the superior fibers project of the into tracts that from the thalamic.

Signup and view all the flashcards

Cerebral Cortex

A layer of gray matter that superficially makes up the cerebral hemisphere.

Signup and view all the flashcards

Cerebral Hemisphere

The largest part of the forebrain, derived from the embryological telencephalon.

Signup and view all the flashcards

Gyri

Ridges found on the cortex.

Signup and view all the flashcards

Sulci

Furrows found on the cortex.

Signup and view all the flashcards

Sulci Depth

Maximizes the surface area of the cerebral cortex.

Signup and view all the flashcards

Falx Cerebri

The great longitudinal fissure which separates the cerebral hemispheres.

Signup and view all the flashcards

Corpus Callosum

Sheet of commissural fibers uniting the cerebral hemispheres.

Signup and view all the flashcards

Intraparietal Sulcus

Divides the rest of the parietal lobe into superior/inferior parietal lobules.

Signup and view all the flashcards

Lateral Fissure

Separates temporal lobe below from the frontal/parietal lobes above.

Signup and view all the flashcards

Frontal Lobe

Constitutes the entire region in front of the central sulcus.

Signup and view all the flashcards

Postcentral Gyrus

Site of primary somatosensory cortex, anterior part lies here.

Signup and view all the flashcards

Calcarine Sulcus

Medial surface landmark marking primary visual cortex location.

Signup and view all the flashcards

Primary Auditory Cortex

Includes primary auditory cortex within superior temporal gyrus.

Signup and view all the flashcards

Heschl's Convolutions

Includes transverse temporal gyri for precise auditory localization.

Signup and view all the flashcards

Cingulate Gyrus

The limbic system is made of sections of the frontal, pariteal and temporal lobes. One example of which is...

Signup and view all the flashcards

Cerebral Cortex

Structure which mediates the integration of sensory information and memory recall.

Signup and view all the flashcards

Limbic System

Allows the storage and retrieval of information processed in hemispheric areas.

Signup and view all the flashcards

Association Cortex

Areas responsible for language comprehension and expression, typically on the dominant side.

Signup and view all the flashcards

Frontal Lobe

Lobe that lies anterior to the central sulcus, functions are motor-related.

Signup and view all the flashcards

Focal Seizures

Dysfunction of higher order processing due to these can cause abnormal movements.

Signup and view all the flashcards

Unilateral Lesion

Impairment from this, can cause mental aphasia, or aphasia.

Signup and view all the flashcards

Aphasia

Loss of language ability from damage to specific brain area.

Signup and view all the flashcards

Korbinian Brodmann

German anatomist, used Nissl method to map cortex cytoarchitecture.

Signup and view all the flashcards

Neocortex

Cerebral cortex with a 6 layer organization (Typical).

Signup and view all the flashcards

Allocortex

More primordial cerebrum with fewer cell layers than neo.

Signup and view all the flashcards

Categories of Cortex

Classified on function it is motor, sensory, or association.

Signup and view all the flashcards

Cortical Layer I

The most superficial layer with many dendrites, involved in synaptic interaction.

Signup and view all the flashcards

Cortical Layer IV

The termination site for afferent input from the specific thalamic nuclei.

Signup and view all the flashcards

Cortical Layer V

The origin of projection fibers to extracortical targets (basal ganglia, etc.).

Signup and view all the flashcards

Cerebral Cortex

Outer surface primarily deals with olfaction, archicortex & paleocortex.

Signup and view all the flashcards

Cerebral Cortex

Site for all sensory modalities to consciously ascend and interpret.

Signup and view all the flashcards

Motor Cortex

Contralateral body side's skilled movement is controlled.

Signup and view all the flashcards

Precentral Gyrus

Area for mapping representations contralaterally, based on precision of control.

Signup and view all the flashcards

Primary Motor Cortex

Receives input from VL nucleus of thalamus's motor cortex's subcortical.

Signup and view all the flashcards

Premotor Cortex

Area, immediately anterior to motor cortex, involved in motor actions.

Signup and view all the flashcards

Frontal Eye Field

Region controlling saccadic eye movements, conjugate deviations.

Signup and view all the flashcards

Broca's Area

Area related to speech articulation in the inferior frontal gyrus.

Signup and view all the flashcards

Prefrontal Cortex

Extensive area anterior to premotor cortex responsible for intellect and judgement.

Signup and view all the flashcards

Orbitofrontal Cortex

This frontal area is linked to the decision making process via the medial dorsal nucleus.

Signup and view all the flashcards

Parietal Lobe

Boundary for the lobes from the temporal and occipital regions.

Signup and view all the flashcards

Primary Somatosensory Cortex

Destination for thalamocortical axons that is functionally important.

Signup and view all the flashcards

Parietal Lobe

Posterior to motor strip, area relates, interprets, to awareness

Signup and view all the flashcards

Parietal Seizures

Lesion leads to abnormal sensations that spread down the contralateral side.

Signup and view all the flashcards

Temporal Lobe

Area for perceptions, the lower temporal, merging caudally, that divides gyri.

Signup and view all the flashcards

Transverse Gyri

Area which marks the location of the primary auditory (sound) cortex.

Signup and view all the flashcards

Primary Auditory Cortex

The part of audital system that receives thalamus inputs, also does partial sound.

Signup and view all the flashcards

Vestibular System

Region which has a complex and uncertain representation (head position etc.).

Signup and view all the flashcards

Occipital Lobe

Behind other lobes is the, contains primary visual.

Signup and view all the flashcards

Basal Ganglia

Nuclear masses within the cerebral hemisphere, including the caudate nucleus, putamen, and globus pallidus.

Signup and view all the flashcards

Amygdala

A basal ganglia structure located within the temporal lobe near the temporal pole that is part of the limbic system

Signup and view all the flashcards

Nucleus Accumbens

The most rostral and ventral part of the corpus striatum, associated with reward and addiction.

Signup and view all the flashcards

Basal Ganglia Functions

Control of movement, posture, and muscle tone

Signup and view all the flashcards

Basal Ganglia Components

Caudate nucleus, putamen, and globus pallidus are anatomically and functionally related and involved in motor control.

Signup and view all the flashcards

Lentiform Nucleus

The putamen and globus pallidus considered together.

Signup and view all the flashcards

Caudate Nucleus

Phylogenetically, the putamen is more closely allied to this structure.

Signup and view all the flashcards

Striatum

A collective term for the caudate nucleus and putamen.

Signup and view all the flashcards

Striatum

The caudate nucleus and putamen together.

Signup and view all the flashcards

Putamen

Lies lateral to the internal capsule and is separated from the globus pallidus by the lateral medullary lamina.

Signup and view all the flashcards

Claustrum

A curved sheet of gray matter lateral to the putamen and medial to the insular cortex.

Signup and view all the flashcards

Caudate Nucleus Shape

The caudate nucleus comprises a head and tapering curved tail.

Signup and view all the flashcards

Putamen

Globus pallidus lies medial to this structure.

Signup and view all the flashcards

Substantia Innominata

Basal part of the rostral forebrain, cholinergic neurons, including the nucleus basalis of Meynert are located here

Signup and view all the flashcards

Striatum Function

Often regarded as the 'input' portion of the basal ganglia.

Signup and view all the flashcards

Cerebral Cortex, Thalamus, Substantia Nigra

Sources of Afferents to the striatum.

Signup and view all the flashcards

Corticostriatal fibers

Frontal and parietal fibers.

Signup and view all the flashcards

Thalamostriatal Projections

Come from the intralaminar nuclei (centromedian and parafascicular) and projects to the ipsilateral thalamus.

Signup and view all the flashcards

Nigrostriatal Projection

Originates from the ipsilateral substantia nigra pars compacta of the midbrain tegmentum.

Signup and view all the flashcards

Nucleus Accumbens Input

Most rostral and ventral portion of the striatum involved in the mesolimbic pathway.

Signup and view all the flashcards

Basal Ganglia and Thalamic Nuclei

The motor thalamic nuclei (ventrolateral and ventral anterior nucleus) and the medial dorsal nucleus.

Signup and view all the flashcards

Ventral Pallidum

An output basal ganglia nucleus that sends fibers to thalamic nuclei.

Signup and view all the flashcards

Addictive drugs - dopamine system

The thalamic target projections and their main neural correlates associated with drug of addiction.

Signup and view all the flashcards

Striatal Projections

Projections of the striatum directed to the globus pallidus and substantia nigra.

Signup and view all the flashcards

Medium Spiny Neurons

Intermediate-sized neurons with spiny dendrites.

Signup and view all the flashcards

Direct Pathway MSNs (dMSNs)

Striatal neurons (dMSNs) project directly to the internal globus pallidus (GPi) and substantia nigra pars reticulata (SNr)

Signup and view all the flashcards

Direct Pathway

The medium spiny neurons that inhibit this structure are involved in motor activity.

Signup and view all the flashcards

Striatal Projections

Utilize GABA for inhibitory projections upon pallidal and nigral neurons.

Signup and view all the flashcards

Cholinergic Interneurons

Aspiny (non-spiny) dendrites and high levels of acetylcholine

Signup and view all the flashcards

Indirect Pathway

Inhibits thalamocortical neurons suppressing unwanted movements.

Signup and view all the flashcards

Parvalbumin Interneurons

The major components of a powerful inhibitory circuit that regulates action potential timing in MSNs.

Signup and view all the flashcards

Globus Pallidus

Two-segments has similar afferent connections but produce distinct efferent projections.

Signup and view all the flashcards

Pars Reticulata

Output structure for this region for basal ganglia.

Signup and view all the flashcards

Medial Pallidal Efferent Fibers

Passes caudally to terminate in the brainstem tegmentum in the pedunculopontine nucleus.

Signup and view all the flashcards

Substantia Nigra Pars Compacta

Has the hallmark of degeneration of dopaminergic neurons in Parkinson’s disease.

Signup and view all the flashcards

Function of Basal Ganglia

Facilitate appropriate movements.

Signup and view all the flashcards

Direct Pathway

Consisting of striatopallidal and striatonigral neurons.

Signup and view all the flashcards

Basal Ganglia Disfunction

Abnormal motor control is indicative of:?

Signup and view all the flashcards

Parkinson's Disease

A disease due to degeneration of dopaminergic neurons, also results in slowing down movement(akinesia).

Signup and view all the flashcards

Hemiballismus

A rare condition is characterised violent choreiform movements

Signup and view all the flashcards

Dystonia

Neurological movement disorder in which sustained muscle contractions cause twisting and repetitive movements

Signup and view all the flashcards

Hypothalamus Definition

A nodal point integrating autonomic, endocrine, emotional, and somatic pathways.

Signup and view all the flashcards

Hypothalamic Boundary

The hypothalamus is the most ventral part of the diencephalon, from which it is separated by the hypothalamic sulcus.

Signup and view all the flashcards

Hypothalamus and 3rd Ventricle

Forms the floor and lower lateral wall of the third ventricle.

Signup and view all the flashcards

Hypothalamus area

Small area circumscribed by the 'crus cerebri', optic chiasm/tracts, and mamillary body.

Signup and view all the flashcards

Lamina Terminalis

The rostral limit; interconnects with the optic chiasm.

Signup and view all the flashcards

Tuber Cinereum

Small elevated area caudal to the optic chiasm from which the infundibulum extends.

Signup and view all the flashcards

Parvo & Magnocellular Systems

Hormone release regulation from the anterior and posterior pituitary lobes.

Signup and view all the flashcards

Integrated Visceral Responses

The hypothalamus's role in integrating visceral responses to stimuli.

Signup and view all the flashcards

Circadian Control

Circadian rhythm coordination, including sleep and wakefulness.

Signup and view all the flashcards

Survival Behaviors

The hypothalamus maintains organ function and drives behaviors for survival.

Signup and view all the flashcards

Skeletal Muscle Regulation

Dependence on the hypothalamus for blood supply regulation.

Signup and view all the flashcards

Complex Behavior

Complex behaviors like sexual responsiveness and maternal care.

Signup and view all the flashcards

Social Behavior Regulated

Impact on aspects of human social behavior.

Signup and view all the flashcards

Neural Circuit Arousal

Moment-to-moment functions controlled via internal state, emotions, and stimuli.

Signup and view all the flashcards

Homeostatic Control

Regulation of five basic physiological needs: blood pressure and appetite.

Signup and view all the flashcards

Body Temperature

Temperature regulation through autonomic and behavioral influences.

Signup and view all the flashcards

Energy Metabolism

Energy metabolism regulation influencing feeding, digestion, and metabolic rate.

Signup and view all the flashcards

Reproduction Regulation

The regulation through the hormonal control of mating, pregnancy, and lactation.

Signup and view all the flashcards

Homeostatic Adaptations

Biochemical & physiological adaptations to preserve stable internal state.

Signup and view all the flashcards

Interoceptor Signals

Signals from internal organs and body fluids for homeostatic responses.

Signup and view all the flashcards

Endocrine/Autonomic Control

The hypothalamus exerts control on the endocrine and autonomic nervous systems.

Signup and view all the flashcards

Exteroceptive Information

Information from outside world influencing behavioral homeostasis.

Signup and view all the flashcards

Survival Instincts

Thirst, hunger, sex, and defense drives are satisfied in stereotyped ways.

Signup and view all the flashcards

Limbic System Role

Adaptive behavior facilitated by learning and memory.

Signup and view all the flashcards

Advanced Analysis

Neocortex capable of advanced environmental and social info analysis.

Signup and view all the flashcards

Circulating Blood Signals

Physical, chemical, and hormonal indicators for body state.

Signup and view all the flashcards

Limbic Signals

Largest input from hippocampus and amygdala.

Signup and view all the flashcards

Modulated Response

Emotions influencing autonomic responses to threats.

Signup and view all the flashcards

Adaptive Responses

If you are prepared to deal with threatening stimuli, you are more likely to survive and reproduce.

Signup and view all the flashcards

Addiction Pathways

Reward and motivated behavior affected by neural pathways.

Signup and view all the flashcards

Obesity Factors

Feeding controlled by the hypothalamus and reward circuitry.

Signup and view all the flashcards

Midsagittal Structures

Midsagittal view shows key structures around the hypothalamus.

Signup and view all the flashcards

Basal Brain Structures

Inferior view shows basal brain surface with structures.

Signup and view all the flashcards

Projection Neurons

Nuclei organized to interface with effector systems in the CNS.

Signup and view all the flashcards

Periventricular Zone

Periventricular and Arcuate nuclei in this zone.

Signup and view all the flashcards

GnRH Neurons

Releases gonadotropin-releasing hormones influencing the pituitary.

Signup and view all the flashcards

LHA role

Orexin-secreting neurons in the LHA contribute to wakefulness.

Signup and view all the flashcards

Posterior Involvement

This plane confirms that the posterior hypothalamus is involved in sympathetic activation and arousal.

Signup and view all the flashcards

Regulation

Regulates circadian rhythms

Signup and view all the flashcards

Diabetes insipidus

Can cause diabetes insipidus if something goes wrong.

Signup and view all the flashcards

Anterior Spinal Artery

Arises from the vertebral arteries, descends along the ventral surface of the spinal cord.

Signup and view all the flashcards

Posterior Spinal Arteries

Arise from vertebral or inferior cerebellar artery, travel caudally on posterolateral cord surface.

Signup and view all the flashcards

Radicular Arteries

Pass through intervertebral foramina, reinforce spinal arteries .

Signup and view all the flashcards

Artery of Adamkiewicz

A radicular artery that arises between T8 and L3, critical for cord supply.

Signup and view all the flashcards

Spinal Cord Venous Drainage

Longitudinal channels primarily made up of anterior and posterior spinal veins.

Signup and view all the flashcards

Posterolateral Veins

Paired veins near dorsal nerve root attachment sites.

Signup and view all the flashcards

Radicular Veins

Drains via anterior and posterior radicular veins into the internal vertebral venous plexus.

Signup and view all the flashcards

Spinal Cord Blood Supply Disorders

Vulnerable in thoracic region; anterior spinal artery occlusion leads to paraplegia/incontinence.

Signup and view all the flashcards

Brain's Arterial Supply

Anterior: internal carotid arteries. Posterior: vertebral arteries.

Signup and view all the flashcards

Internal Carotid Artery

Arises from common carotid, enters cranium via carotid canal.

Signup and view all the flashcards

Internal Carotid Location

Carotid triangle, superior thyroid border, C3-C5 level.

Signup and view all the flashcards

Internal Carotid Segments

C1 - Cervical, C2 - Petrous, C3 - Cavernous, C4 - Cerebral.

Signup and view all the flashcards

Cervical Part ICA

Runs from origin to carotid canal orifice. Cervical segment gives off no branches.

Signup and view all the flashcards

Petrous Part ICA

From carotid canal to cavernous sinus entry, with caroticotympanic and Vidian artery branches.

Signup and view all the flashcards

Cavernous Part ICA

In cavernous sinus, gives branches to cranial nerves and sinus walls.

Signup and view all the flashcards

Cerebral Part ICA

Final ICA segment, gives ophthalmic, posterior communicating, anterior choroidal arteries.

Signup and view all the flashcards

Ophthalmic Artery

Major branch after cavernous sinus exit; enters optic canal to supply orbit and eye.

Signup and view all the flashcards

Posterior Communicating Artery

Connects internal carotid and basilar systems, supplies internal capsule, thalamus.

Signup and view all the flashcards

Anterior Choroidal Artery

Supplies optic tract, choroid plexus, hippocampus, internal capsule.

Signup and view all the flashcards

Anterior Cerebral Artery (ACA)

One branch supplies frontal and parietal medial aspects.

Signup and view all the flashcards

Middle Cerebral Artery (MCA)

Branches supply orbital, frontal, parietal, and temporal lobes.

Signup and view all the flashcards

Vertebral Artery

Paired arteries arising in the neck and provide to the spinal cord, brainstem, lower brain etc.

Signup and view all the flashcards

Vertebral Artery

Joins to form basilar artery; cervical, spinal, cranial branches..

Signup and view all the flashcards

Basilar Artery

Single vessel from vertebral arteries, divides into posterior cerebral arteries.

Signup and view all the flashcards

Circle of Willis

Anastomotic ring at brain base; connects carotid and vertebrobasilar systems.

Signup and view all the flashcards

Posterior Communicating Artery

Connects internal carotid with posterior cerebral arteries.

Signup and view all the flashcards

Posterior Cerebral Arteries

Terminal branches of the basilar artery which supply occipital lobe.

Signup and view all the flashcards

Perforating Arteries

Small arteries from Circle of Willis penetrating brain surface.

Signup and view all the flashcards

Brain's Venous Drainage

Cerebral, dural systems into internal jugular vein.

Signup and view all the flashcards

Superficial Venous System

Sagittal sinuses, dural sinuses. Drain into sigmoid sinuses.

Signup and view all the flashcards

Deep Venous System

Deep veins drain to great cerebral vein of Galen, then to straight sinus.

Signup and view all the flashcards

Transverse Sinus

superior saggital drains both hemispheres

Signup and view all the flashcards

Internal Jugular Vein

cavernous and the petrosal sinus

Signup and view all the flashcards

Deep Cerebral Veins

great cerebral vein of Galen

Signup and view all the flashcards

Disorders of blood supply

stroke and other blood disease

Signup and view all the flashcards

What can lead to death?

thrombosis of the sinuses

Signup and view all the flashcards

Study Notes

  • Arterial Supply of the Spinal Cord*

  • Longitudinal arterial vessels run the length of the spinal cord.

  • The anterior spinal artery arises in a Y-shaped configuration from the two vertebral arteries at the level of the medulla oblongata.

  • This artery descends along the ventral surface of the cord in the midline.

  • The paired posterior spinal arteries arise from either the vertebral arteries or the posterior inferior cerebellar arteries.

  • The paired posterior spinal arteries run caudally on the posterolateral surface of the spinal cord.

  • The anterior and posterior spinal arteries alone are insufficient to supply the cord below cervical levels.

  • Serial reinforcement occurs by anastomosis with radicular arteries derived from segmental vessels, including the ascending cervical, intercostal, and lumbar arteries.

  • Radicular Arteries*

  • These arteries pass through the intervertebral foramina.

  • They divide into anterior and posterior branches

  • The anterior and posterior branches run with the dorsal and ventral spinal nerve roots, respectively.

  • A large radicular artery, known as the great radicular artery or artery of Adamkiewicz, may arise from a lateral intercostal or lumbar artery at any level between T8 and L3.

  • Venous Drainage of the Spinal Cord*

  • Six longitudinal interconnecting venous channels exist.

  • These channels consist primarily of anterior and posterior spinal veins, which run in the midline. Posterolateral veins are bilaterally paired and sometimes incomplete.

  • Posterolateral veins are situated near the lines of attachment of the dorsal nerve roots.

  • All vessels drain via anterior and posterior radicular veins into the internal vertebral venous plexus, also known as the epidural venous plexus.

  • The internal venous plexus communicates with an external vertebral venous plexus.

  • The plexuses also communicate with the ascending lumbar veins and the azygos veins.

  • Disorders of the Blood Supply of the Spinal Cord*

  • The blood supply of the spinal cord is most vulnerable in the thoracic region and in the ventral portion of the cord.

  • Occlusion of the anterior spinal artery leads to an acute thoracic cord syndrome with paraplegia and incontinence.

  • With occlusion of the anterior spinal artery, the spinothalamic modalities of pain and temperature are preferentially lost.

  • The proprioceptive functions of the dorsal columns are relatively preserved after occlusion of the anterior spinal artery.

  • Vascularization of the Brain*

  • Blood is supplied to the brain by two pairs of vessels: the internal carotid arteries (anterior circulation) and the vertebral arteries (posterior circulation).

  • The internal carotid artery arises from the common carotid artery and enters the middle fossa of the cranial cavity through the carotid canal.

  • The internal carotid artery is one of two terminal branches of the common carotid artery.

  • Internal carotid arteries and their branches supply arterial blood to the cerebral hemispheres, basal ganglia, eyes, nose, nasal cavity and paranasal sinuses.

  • The internal carotid arteries and their branches make up the anterior circulation system of the brain.

  • The internal carotid artery originates from the site where the common carotid artery bifurcates at approximately the cervical vertebral body 4 This is called the carotid bifurcation.

  • Internal Carotid Artery – Carotid Triangle*

  • The artery is found within the carotid triangle of the neck.

  • The artery is at the level of the superior border of the thyroid cartilage or approximately at the third to fifth cervical vertebral levels (C3 - C5).

  • Four Subdivisions of the Internal Carotid Artery*

  • The internal carotid artery is divided into four segments by the anatomical structures it crosses.

  • Cervical or Extracranial Part: Goes through the neck (C1)

  • Petrous Part: Travels through the petrous part of the temporal bone (C2).

  • Cavernous Part: Passes through the cavernous sinus (C3).

  • Cerebral or Supraclinoid Part: Located within the cranial cavity after the internal carotid artery pierces the dura mater (C4).

  • Internal Carotid Artery - Cervical Part*

  • The cervical part extends from its origin to the external orifice of the carotid canal.

  • It ascends posteromedially to the external carotid artery and anterior to the transverse processes of the first three cervical vertebrae (C3 - C1).

  • The segment travels within the carotid sheath together with the internal jugular vein and the vagus nerve (CN X).

  • The cervical segment gives no branches.

  • It enters the skull through the carotid canal of the petrous part of the temporal bone.

  • Internal Carotid Artery - Petrous Part*

  • It extends from the external orifice of the carotid canal to the site where the internal carotid artery enters the cavernous sinus.

  • The petrous part is divided into a short vertical portion that curves anteriorly and medially and continues as a horizontal portion.

  • The ptrous part crosses the cartilage occluding the foramen lacerum (it does not go through it) and enters the cavernous sinus.

  • Initially, it is located anterior and medial to the cochlea and the tympanic cavity.

  • The internal carotid artery is encircled and surrounded by small veins and branches of the superior cervical ganglion of the sympathetic trunk, forming a carotid plexus.

  • The petrous part gives off several small branches, including the caroticotympanic artery and the Vidian artery. The caroticotympanic artery passes from the carotid canal to the tympanic cavity, anastomosing with the anterior tympanic branch of the maxillary artery and the stylomastoid artery of the posterior auricular artery.

  • The Vidian artery (artery of the pterygoid canal) is inconsistent and may sometimes be absent.

  • It travels through the pterygoid canal with the Vidian nerve and anastomoses with a branch of the maxillary artery

  • It supplies the auditory tube, tympanic cavity, and upper pharynx.

  • Internal Carotid Artery - Cavernous Part*

  • The cavernous part travels from where the internal carotid artery enters the cavernous sinus to where it exits it.

  • The internal carotid Artery ascends towards the posterior clinoid process, then deflects anteriorly flanking the body of the sphenoid bone

  • The internal carotid artery curves upwards medial to the anterior clinoid process, ending at the proximal dural ring that incompletely encircles the internal carotid artery

  • It then pierces the dura mater and exits through the roof of the sinus. The curve of the cavernous part is known as the carotid siphon.

  • Several cranial nerves run through the cavernous sinus lateral to it, including the oculomotor nerve (CN III), trochlear nerve (CN IV), ophthalmic and maxillary divisions of the trigeminal nerve (CN V1 and CN V2), and abducens nerve (CN VI).

  • The cavernous part gives off branches that supply the trigeminal ganglion, walls of the cavernous sinus, and nerves.

  • Branches of the cavernous segment include the meningohypophyseal trunk and the inferolateral trunk.

  • It is accompanied by the internal carotid plexus originating from the superior cervical ganglion.

  • The meningohypophyseal trunk is a small vessel that usually originates from the proximal portion of the cavernous segment.

  • The meningohypophyseal trunk supplies the pituitary gland, clivus, oculomotor (CN III), trochlear (CN IV), trigeminal (CN V) and abducens (CN VI) nerves, tentorium cerebelli and adjacent dura mater.

  • The inferolateral trunk or the artery of the inferior cavernous sinus arises laterally from the midportion of the cavernous segment and goes in the inferior direction.

  • It travels between the trochlear nerve (CN IV) and the ophthalmic division of the mandibular nerve (CN V1) and gives off several branches.

  • These branches supply the oculomotor (CN III), trochlear (CN IV), trigeminal (CN V) and abducens (CN VI) cranial nerves.

  • Small capsular arteries supply the wall of the cavernous sinus.

  • Internal Carotid Artery – Intracranial/Cerebral Part*

  • The final portion is the intracranial or supraclinoid part (C4).

  • After the internal carotid artery leaves the cavernous sinus and pierces the dura mater, it travels between the optic nerve (CN II) medially and the oculomotor nerve (CN III) laterally.

  • The artery reaches the anterior perforated substance at the medial end of the lateral sulcus.

  • It bifurcates into two terminal branches: the anterior cerebral artery and the middle cerebral artery.

  • Along its course, the intracranial part of the artery gives off several branches, including the ophthalmic, posterior communicating and anterior choroidal arteries.

  • Ophthalmic Artery*

  • This artery is the first major branch of the internal carotid artery.

  • It arises right after the internal carotid artery pierces through the dura mater and exits the cavernous sinus.

  • It originates medially to the anterior clinoid process of the sphenoid bone and has a relatively short intracranial course.

  • It pierces the dura mater, enters the optic canal, and passes into the orbit with the optic nerve (CN II).

  • Within the orbit, the ophthalmic artery goes along its medial wall, supplying the orbit and its contents, such as the eyeball, extraocular muscles and peri-ophthalmic tissue.

  • Posterior Communicating Artery (PCA)*

  • It originates from the posterior aspect of the internal carotid artery.

  • It runs posteriorly above the oculomotor nerve (CN III) and anastomoses with the terminal branch of the basilar artery - the posterior cerebral artery.

  • The PCA connects the anterior and posterior circulation systems of the brain. It participates in the formation of the circle of Willis and gives off several small branches that supply the internal capsule, third ventricle, thalamus, subthalamus, hypothalamus, optic chiasm and mammillary bodies.

  • Anterior Choroidal Artery*

  • This arises from the posterolateral aspect of the intracranial part of the internal carotid artery near the termination site.

  • The anterior choroidal artery supplies the optic tract, the choroid plexus of the lateral ventricle, the hippocampus and some of the deep structures of the hemisphere including the internal capsule, globus pallidus and tail of the caudate nucleus.

  • Terminal Branches of the Internal Carotid Artery*

  • The middle cerebral artery and anterior cerebral artery are the terminal branches of the internal carotid artery.

  • Anterior Cerebral Artery (ACA) and Its Branches*

  • The ACA is one of the terminal branches of the internal carotid artery that supplies medial aspects of the frontal and parietal lobes of the cerebral hemispheres.

  • It passes medial to the great longitudinal fissure of the cerebrum.

  • The ACA winds around the genu of the corpus callosum and goes along the medial surface of the cerebral hemisphere, reaching the parietooccipital sulcus. The artery consists of A1-from the termination of the internal carotid to the junction with the anterior communicating artery; A2 - from the junction with the anterior communicating artery to the origin of the callosomarginal artery; A3 - extends from the distal origin of the callosomarginal artery, also called the pericallosal artery.

  • The artery gives rise to two types of branches: cortical and central branches.

  • The artery supplies the motor and somatosensory areas of the cerebral cortex, orbital gyrus, gyrus rectus, medial surface of the frontal and parietal lobes, cingulate gyrus, and the fornix.

  • The central branches arise from its proximal portion and comprise the long striate arteries.

  • Anterior Cerebral Artery*

  • Branches ramify over the medial surface of the frontal and parietal lobe.

  • The artery supplies the motor and sensory cortices for the lower limb.

  • Supplies a narrow lateral band of the frontal and parietal cortices via fine terminal branches through the great longitudinal fissure.

  • Middle Cerebral Artery and Its Branches*

  • This artery is one of the terminal branches of the internal carotid artery.

  • The middle cerebral artery supplies subcortical (central) and cortical regions of the cerebral hemispheres.

  • Central branches are distributed to subcortical structures of the cerebrum. The lenticulostriate arteries supply structures as the putamen & pallidum complex, internal capsule, and caudate nucleus.

  • From its origin, the artery continues into the lateral sulcus of the cerebrum and ascends posteriorly on the insula. It branches that project to the lateral aspect of the cerebral cortex supply blood to the orbital, frontal, parietal and temporal lobes. Supplies the motor and somatosensory cortices, and the auditory area of the cerebral cortex.

  • Orbital branches supply the inferior frontal gyrus, as well as the lateral orbital surface of the frontal lobe.

  • Frontal branches supply the precentral, middle, and inferior frontal gyri.

  • Parietal branches supply the postcentral gyrus, inferior parietal lobule, and lower part of the superior parietal lobule.

  • Temporal branches are distributed to the lateral surface of the temporal lobe.

  • It is the largest cerebral artery and its cortical territory is the most extensive.

  • Branches supply the auditory cortex and insula within the depth of the lateral fissure.

  • Branches supply to structures listed so far supplied by the internal carotid system.

Arterial Supply of Brain Overview

  • Its branches supply virtually the whole of the lateral surface of the frontal, parietal and temporal lobes Territory includes the primary motor and sensory cortices for the whole of the body, excluding the lower limb, as supplied by the anterior cerebral artery
  • The artery passes lateraly from its origin to enter the lateral fissure within which it subdivides.
  • Vertebrobasilar System*

  • The vertebral artery (Latin: arteria vertebralis) is a paired artery found on each side of the neck. It provides arterial blood supply to the spinal cord, lower portion of the brainstem, posterior aspects of the cerebellum and cerebral hemispheres, and the meninges. The left vertebral artery is usually larger than the right.
  • Vertebral Arteries*

  • The artery is usually is subdivided into four segments based on its course.
  • V1: First segment starts at the origin of the vertebral artery when it branches off the subclavian artery and travels to the transverse foramen of the sixth cervical vertebra (C6).
  • V2: Second segment ascends through the transverse foramina of the sixth through second cervical vertebrae.
  • V3: Third segment makes a postero-lateral turn to enter the transverse foramen of the atlas (C1) and pierces the posterior atlantooccipital membrane to enter the vertebral canal. V4: The vertebral artery pierces the dura mater and arachnoid mater, entering the cranial cavity via the foramen magnum and joins the contralateral vertebral artery to form the basilar artery.
  • The vertebral artery gives off cervical and cranial brances

Vertebral Arteries - Cervical Branches

  • These branches are called cervical branches, and are spinal and muscular branches
  • The spinal branches supply the spinal cord via the intervertebral foramina, also suppling the bodies of the cervical vertebrae
  • Muscular branches supply the deep muscles of the neck and can form anastomoses with the occipital branches of the external carotid artery.
  • Vertebral Arteries - Spinal Branches*

  • Within the skull, the vertebral artery usually gives off several cranial branches, including the anterior spinal artery, posterior spinal arteries, posterior inferior cerebellar artery, meningeal arteries, and medullary arteries.
  • The anterior spinal artery arises close to the basilar artery from the confluence of two smaller arteries, passing within the anterior median fissure.
  • This artery is the primary source that supplies arterial blood to the spinal cord
  • Vertebral Arteries – Spinal and Cerebellar Branches*

  • The posterior spinal arteries normally arise near the medulla oblongata and descends along the right or left posterolateral sulcus of the spinal cord.
  • Posterior spinal arteries supply the posterior one-third of the spinal cord and can also arise from the posterior inferior cerebellar arteries.
  • The posterior inferior cerebellar artery is a large paired artery that originates at the level of the olive of the medulla oblongata and passes upwards along the side of the medulla near the roots of CN IX-XI.
  • The posterior inferior cerebellar artery courses along the inferior part of the pons and supplies the lower part of the medulla oblongata and cerebellum.
  • Vertebral Arteries – Cranial Branches*

  • The meningeal branches of the vertebral artery originate near the foramen magnum and supply the dura mater of the posterior cranial fossa and falx cerebelli.
  • Basilar Artery*

  • This artery is a single large blood vessel that is formed by the union of the two vertebral arteries.
  • Originates at the mid-medullary level, ascends vertically, and divides into two terminal branches, the posterior cerebral arteries.
  • It gives off several side branches, including pontine branches, labyrinthine artery, anterior inferior cerebellar artery and superior cerebellar artery.

Basilar Artery Branches

  • pontine branches are small vessels that supply the pons from front and sides as it travels along the pons.
  • The labyrinthine artery is a branch that sometimes arises from the lower part and supplies the vestibular apparatus and the cochlea.
  • The anterior inferior cerebellar artery originates from the inferior part and supplies the inferior cerebellar surface.
  • The superior cerebellar artery arises from the superior part and supplies the superior cerebellar surface, pineal body, superior medullary velum, and tela choroidea of the third ventricle.
  • Thus, regions supplied by the basilar artery include the pons, structures of the inner ear, inferior and superior cerebellar surfaces, upper medulla oblongata, pineal body, superior medullary velum, and tela choroidea of the third ventricle.
  • Circle of Willis*

  • The circle the internal carotid and vertebral basilar systems are joined by two thin vessels, the posterior communicating arteries.
  • Its completes an anastomosis of vessels on the base of the brain.
  • This circle encircles the optic chiasm and the floor of the hypothalamus and midbrain as an anastomatic arrangement of vessels can compensate an obstruction or narrowing of any of the vessels that make up the circle
  • the size of the communicating arteries varies between individuals.
  • The nine sides consist of a short anterior communicating artery, proximal ends of an anterior anterior cerebral artery, distal of Internal Carotid Arteries and a postier cerebral artery.
  • Overall the arteries from the circle of Willis provide the majority of the arterial supply to the brain
  • Posterior Communicating Arteries*

  • The arteries extend posteriorly from the intracranial portion of internal carotid arteries, connecting each to the ipsilateral posterior cerebral artery.
  • The arteries supplies Mamillary bodies, Tuber cinereum, Optic chiasm ,Hypothalamus, Oculomotor nerve, and medial thalamic surface and wall of the 3rd ventricle

Posterior Cerebral Arteries

  • the two arteries are the terminal branches of the basilar artery
  • Traveling postero-laterally around the superior part of the pons, these arteries give off branches that travel to the pons, midbrain, thalamus, and choroid plexuses of the third and fourth ventricles
  • Split into terminal brancs when reaches the inferior hemispheres on medial and lateral portions
  • The arteries travel posteromedially supplying parietal, cuneus, precuncus and corpus callosum
  • the arteries as well travel postierolatley on aspects of poster portions
  • Perforating Arteries*

  • Numerous arteries depart from the circle of Willis and penetrate the surface of the brain. These are known as perforating arteries and consist of two main groups:
  • Anterior arteries which has a perforated actions by some traits .
  • Posterior arteries which has a some trait The perfortic arteries supply large ganglion ports, thalamus and internal capsule .
  • Venous Drainage of The Brain*

  • Cerebral vascular venous drainage occurs via a number of small venous channels which form cerebral veins that empty into the internal jugular vein, formed by the cerebral sinsue and blood.
  • The drainage has small system on the cortex, blood come from cerebral cortex, and the drainage meets posterior or some part with those that what comes from action.
  • Cerebral Venous Drainage*

  • Superfical division has come to work cerebral.
  • Deep division has function with some. There superical has those with location but the meet traits show on action by come
  • Vascular Superficial Veins Of the Brain*

  • The superficial of it side will helps those that show plus some with help some time show. Is it about what helps so often get to that action Often traits get from parts by what helps show with trait Often has it get act out action by the place
  • Dural Venous Sinuses*

  • it show some helps those often actions. Where act shows by comes act to the body but often can show on other
  • Deep Cerebral Veins*

These venous action has small traits location. Where some actions by come small areas.

  • Disorders of the Blood Supply of the Brain*

Where small get function by actions but traits can cause a stroke It will go what cause traits Stroke action help but what gets to help

  • Disorders of Blood Supply & Diseases of the Venous Sinuses*

  • The process can cause issues but help or not show Stroke: A type is with hits that body and its act where, the act get helps show by what acts

Diseases of the Venous Sinuses:

  • Diseases of the Venous Sinuses have come traits those sides can come to act Those that has action by sides it will what comes act
  • Vein problems can arise to many that needs. Action comes the area.
  • Some action it has action what it act in trait.
  • The help of item it helps or not it what get body to act
  • Often it can gets for the help what circuit will And action that show for where act trait sides

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Neuron Structure Quiz
6 questions

Neuron Structure Quiz

GladLepidolite6058 avatar
GladLepidolite6058
Neuron Structure and Action Potential
63 questions
Neuron Anatomy Quiz
8 questions

Neuron Anatomy Quiz

LuxuriantOstrich avatar
LuxuriantOstrich
Use Quizgecko on...
Browser
Browser