The Monoamine Hypothesis and Antidepressants Quiz
10 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which neurotransmitters are believed to be functionally deficient in depression according to the monoamine hypothesis?

  • Noradrenaline and dopamine
  • Serotonin and GABA
  • Noradrenaline and serotonin (correct)
  • Dopamine and serotonin

How do antidepressants improve the mood of the patient?

  • By increasing dopamine levels
  • By blocking the reuptake of monoamines (correct)
  • By inhibiting the breakdown of monoamines
  • By decreasing serotonin and noradrenaline levels

Which class of antidepressants primarily block the reuptake of serotonin?

  • Tricyclic antidepressants (TCAs)
  • Monoamine oxidase inhibitors (MAOIs)
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Selective serotonin reuptake inhibitors (SSRIs) (correct)

Which class of antidepressants block the reuptake of both serotonin and noradrenaline?

<p>Serotonin-norepinephrine reuptake inhibitors (SNRIs) (B)</p> Signup and view all the answers

How do monoamine oxidase inhibitors (MAOIs) affect serotonin and noradrenaline?

<p>By preventing their breakdown (B)</p> Signup and view all the answers

Select the correct statement on selective serotonin reuptake inhibitor (SSRI)

<p>It crosses the blood-brain barrier (C)</p> Signup and view all the answers

Select the correct statement on tricyclic antidepressant (TCA)

<p>It can be metabolized by liver cytochrome CYP2D6 enzymes (B)</p> Signup and view all the answers

Select the correct statement about side effects of an antidepressant

<p>TCA causes sedating effect by blocking histamine H1 receptors (D)</p> Signup and view all the answers

Select the correct statement on clinical use of antidepressant

<p>A suicidal ideation or indication should be closely monitored within first to second weeks of antidepressant regime (B)</p> Signup and view all the answers

Select the suitable antidepressant for a patient that moderately depressed but has a history of heart attack (last year)

<p>SSRI (C)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser