The Monoamine Hypothesis and Antidepressants Quiz

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Which neurotransmitters are believed to be functionally deficient in depression according to the monoamine hypothesis?

Noradrenaline and dopamine

Serotonin and GABA

Noradrenaline and serotonin (correct)

Dopamine and serotonin

How do antidepressants improve the mood of the patient?

By increasing dopamine levels

By blocking the reuptake of monoamines (correct)

By inhibiting the breakdown of monoamines

By decreasing serotonin and noradrenaline levels

Which class of antidepressants primarily block the reuptake of serotonin?

Tricyclic antidepressants (TCAs)

Monoamine oxidase inhibitors (MAOIs)

Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Selective serotonin reuptake inhibitors (SSRIs) (correct)

Which class of antidepressants block the reuptake of both serotonin and noradrenaline?

Serotonin-norepinephrine reuptake inhibitors (SNRIs) Signup and view all the answers

How do monoamine oxidase inhibitors (MAOIs) affect serotonin and noradrenaline?

By preventing their breakdown Signup and view all the answers

Select the correct statement on selective serotonin reuptake inhibitor (SSRI)

It crosses the blood-brain barrier Signup and view all the answers

Select the correct statement on tricyclic antidepressant (TCA)

It can be metabolized by liver cytochrome CYP2D6 enzymes Signup and view all the answers

Select the correct statement about side effects of an antidepressant

TCA causes sedating effect by blocking histamine H1 receptors Signup and view all the answers

Select the correct statement on clinical use of antidepressant

A suicidal ideation or indication should be closely monitored within first to second weeks of antidepressant regime Signup and view all the answers

Select the suitable antidepressant for a patient that moderately depressed but has a history of heart attack (last year)

SSRI Signup and view all the answers

The Monoamine Hypothesis and Antidepressants Quiz

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Questions and Answers

Which neurotransmitters are believed to be functionally deficient in depression according to the monoamine hypothesis?

How do antidepressants improve the mood of the patient?

Which class of antidepressants primarily block the reuptake of serotonin?

Which class of antidepressants block the reuptake of both serotonin and noradrenaline?

How do monoamine oxidase inhibitors (MAOIs) affect serotonin and noradrenaline?

Select the correct statement on selective serotonin reuptake inhibitor (SSRI)

Select the correct statement on tricyclic antidepressant (TCA)

Select the correct statement about side effects of an antidepressant

Select the correct statement on clinical use of antidepressant

Select the suitable antidepressant for a patient that moderately depressed but has a history of heart attack (last year)

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