Control of Gene Expression Learning Objectives
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Questions and Answers

Which process alters the sequence of mRNA?

  • Editing (correct)
  • Methylation
  • Acetylation
  • Translocation

What happens when a premature stop codon is produced in apo-B-48?

  • The protein becomes shorter (correct)
  • The mRNA becomes unstable
  • The mRNA is degraded
  • The protein becomes longer

Which molecules bind to specific RNA structures and affect mRNA stability and translation?

  • Iron-regulatory proteins (correct)
  • Transcription factors
  • miRNAs
  • Histones

What is the role of miRNAs in gene expression?

<p>They prevent protein synthesis (B)</p> Signup and view all the answers

What effect does acetylation of histones have on gene expression?

<p>It promotes gene expression (B)</p> Signup and view all the answers

What effect does methylation of DNA have on gene expression?

<p>It represses gene expression (B)</p> Signup and view all the answers

Where do transcription factors act to regulate target genes?

<p>Nucleus (B)</p> Signup and view all the answers

What is the role of mRNA stability in iron metabolism?

<p>It regulates iron-related proteins (B)</p> Signup and view all the answers

Which process leads to mRNA degradation or translational inhibition?

<p>miRNA binding (A)</p> Signup and view all the answers

What is changed by deamination to produce a premature stop codon in apo-B-48?

<p>A single base (D)</p> Signup and view all the answers

Which condition activates the lac operon in lactose metabolism?

<p>lac+ and glu- (C)</p> Signup and view all the answers

What role does the lac repressor play in the lac operon?

<p>It represses transcription (B)</p> Signup and view all the answers

What happens to cAMP levels when glucose is scarce?

<p>They rise (C)</p> Signup and view all the answers

What is the role of CAP in the lac operon regulation?

<p>It enhances RNA polymerase binding (C)</p> Signup and view all the answers

What is the role of the stringent factor in the stringent response?

<p>It conserves energy (B)</p> Signup and view all the answers

What happens to the trp operon in trp high conditions?

<p>It is repressed (C)</p> Signup and view all the answers

What happens to the trp operon in trp low conditions?

<p>It is activated (C)</p> Signup and view all the answers

What is the role of attenuation in trp operon regulation?

<p>It prematurely terminates transcription (D)</p> Signup and view all the answers

Which structural motif is used by proteins to bind DNA?

<p>All of the above (D)</p> Signup and view all the answers

What is the role of STF in the coordinate regulation of the galactose circuit in yeast?

<p>It recruits chromatin remodeling complexes (C)</p> Signup and view all the answers

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