32.The Impact of Diabetes on Perioperative Outcomes
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Questions and Answers

Which of the following is NOT mentioned as a factor that may influence the management of intraoperative glucose?

  • Pregnancy
  • Type of operation
  • Type of diabetes (correct)
  • Expected global CNS insult

According to the World Health Organization's surgical safety checklist bundle, what is the target perioperative blood glucose concentration?

  • 4 to 6 mmol/L
  • 2 to 4 mmol/L
  • 6 to 10 mmol/L (correct)
  • 10 to 12 mmol/L

What is the impact of poor perioperative glycemic control on the risk of postoperative infection?

  • Moderate impact
  • No impact
  • Slight impact
  • Significant impact (correct)

Which trial demonstrated the benefit of tight glucose control in medical ICU patients?

<p>The trial in Leuven, Belgium (D)</p> Signup and view all the answers

What were the blood glucose levels associated with moderate and severe hypoglycemia in the NICE-SUGAR trial?

<p>41-70 mg/dL and ≤40 mg/dL (D)</p> Signup and view all the answers

What is the association between intensive glucose control and death in critically ill patients?

<p>Intensive glucose control increases the risk of death (C)</p> Signup and view all the answers

Which of the following is considered more important for perioperative outcome than diabetes itself?

<p>The end-organ effects of diabetes (B)</p> Signup and view all the answers

What is the target perioperative blood glucose concentration recommended by the World Health Organization's surgical safety checklist bundle?

<p>6 to 10 mmol/L (C)</p> Signup and view all the answers

Which of the following is a potential risk of tight perioperative control of blood glucose levels?

<p>Hypoglycemia (B)</p> Signup and view all the answers

What is the impact of poor perioperative glycemic control on the risk of postoperative infection?

<p>Significant impact (A)</p> Signup and view all the answers

Where is much of the research on perioperative control derived from?

<p>ICU (C)</p> Signup and view all the answers

What is the recommended range for perioperative blood glucose concentration according to the World Health Organization's surgical safety checklist bundle?

<p>6-10 mmol/L (B)</p> Signup and view all the answers

What is the association between tight glucose control and the severity of diabetes itself?

<p>Negative association (B)</p> Signup and view all the answers

Which of the following may influence the management of intraoperative glucose?

<p>All of the above (D)</p> Signup and view all the answers

What is the impact of poor perioperative glycemic control on the risk of postoperative infection?

<p>Significant impact (B)</p> Signup and view all the answers

What does the World Health Organization's surgical safety checklist bundle suggest for perioperative blood glucose control?

<p>Tight control (B)</p> Signup and view all the answers

Which trial examined the associations between moderate and severe hypoglycemia and death among critically ill patients in ICUs?

<p>The NICE-SUGAR trial (D)</p> Signup and view all the answers

What is the range of blood glucose levels associated with moderate hypoglycemia in the NICE-SUGAR trial?

<p>41-70 mg/dL [2.3-3.9 mmol/L] (D)</p> Signup and view all the answers

What is the range of blood glucose levels associated with severe hypoglycemia in the NICE-SUGAR trial?

<p>≤40 mg/dL [2.2 mmol/L] (B)</p> Signup and view all the answers

What is the association between intensive glucose control and death in critically ill patients?

<p>There is a positive association (D)</p> Signup and view all the answers

Which type of shock is the association between intensive glucose control and death strongest for?

<p>Distributive shock (C)</p> Signup and view all the answers

What was the purpose of the trial on perioperative management mentioned in the text?

<p>To review the optimal perioperative management (A)</p> Signup and view all the answers

What were the blood glucose levels associated with moderate and severe hypoglycemia in the NICE-SUGAR trial?

<p>Moderate: 41-70 mg/dL [2.3-3.9 mmol/L], Severe: ≤40 mg/dL [2.2 mmol/L] (C)</p> Signup and view all the answers

What is the focus of the guidelines developed on insulin infusions in the critical care unit?

<p>Tight glucose control (C)</p> Signup and view all the answers

What was the impact of intensive glucose control on the risk of death in the NICE-SUGAR trial?

<p>Increased risk (B)</p> Signup and view all the answers

Which country was the first major trial demonstrating the benefit of tight glucose control conducted in?

<p>Belgium (A)</p> Signup and view all the answers

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