32.The Impact of Diabetes on Perioperative Outcomes
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Questions and Answers

Which of the following is NOT mentioned as a factor that may influence the management of intraoperative glucose?

  • Pregnancy
  • Type of operation
  • Type of diabetes (correct)
  • Expected global CNS insult
  • According to the World Health Organization's surgical safety checklist bundle, what is the target perioperative blood glucose concentration?

  • 4 to 6 mmol/L
  • 2 to 4 mmol/L
  • 6 to 10 mmol/L (correct)
  • 10 to 12 mmol/L
  • What is the impact of poor perioperative glycemic control on the risk of postoperative infection?

  • Moderate impact
  • No impact
  • Slight impact
  • Significant impact (correct)
  • Which trial demonstrated the benefit of tight glucose control in medical ICU patients?

    <p>The trial in Leuven, Belgium</p> Signup and view all the answers

    What were the blood glucose levels associated with moderate and severe hypoglycemia in the NICE-SUGAR trial?

    <p>41-70 mg/dL and ≤40 mg/dL</p> Signup and view all the answers

    What is the association between intensive glucose control and death in critically ill patients?

    <p>Intensive glucose control increases the risk of death</p> Signup and view all the answers

    Which of the following is considered more important for perioperative outcome than diabetes itself?

    <p>The end-organ effects of diabetes</p> Signup and view all the answers

    What is the target perioperative blood glucose concentration recommended by the World Health Organization's surgical safety checklist bundle?

    <p>6 to 10 mmol/L</p> Signup and view all the answers

    Which of the following is a potential risk of tight perioperative control of blood glucose levels?

    <p>Hypoglycemia</p> Signup and view all the answers

    What is the impact of poor perioperative glycemic control on the risk of postoperative infection?

    <p>Significant impact</p> Signup and view all the answers

    Where is much of the research on perioperative control derived from?

    <p>ICU</p> Signup and view all the answers

    What is the recommended range for perioperative blood glucose concentration according to the World Health Organization's surgical safety checklist bundle?

    <p>6-10 mmol/L</p> Signup and view all the answers

    What is the association between tight glucose control and the severity of diabetes itself?

    <p>Negative association</p> Signup and view all the answers

    Which of the following may influence the management of intraoperative glucose?

    <p>All of the above</p> Signup and view all the answers

    What is the impact of poor perioperative glycemic control on the risk of postoperative infection?

    <p>Significant impact</p> Signup and view all the answers

    What does the World Health Organization's surgical safety checklist bundle suggest for perioperative blood glucose control?

    <p>Tight control</p> Signup and view all the answers

    Which trial examined the associations between moderate and severe hypoglycemia and death among critically ill patients in ICUs?

    <p>The NICE-SUGAR trial</p> Signup and view all the answers

    What is the range of blood glucose levels associated with moderate hypoglycemia in the NICE-SUGAR trial?

    <p>41-70 mg/dL [2.3-3.9 mmol/L]</p> Signup and view all the answers

    What is the range of blood glucose levels associated with severe hypoglycemia in the NICE-SUGAR trial?

    <p>≤40 mg/dL [2.2 mmol/L]</p> Signup and view all the answers

    What is the association between intensive glucose control and death in critically ill patients?

    <p>There is a positive association</p> Signup and view all the answers

    Which type of shock is the association between intensive glucose control and death strongest for?

    <p>Distributive shock</p> Signup and view all the answers

    What was the purpose of the trial on perioperative management mentioned in the text?

    <p>To review the optimal perioperative management</p> Signup and view all the answers

    What were the blood glucose levels associated with moderate and severe hypoglycemia in the NICE-SUGAR trial?

    <p>Moderate: 41-70 mg/dL [2.3-3.9 mmol/L], Severe: ≤40 mg/dL [2.2 mmol/L]</p> Signup and view all the answers

    What is the focus of the guidelines developed on insulin infusions in the critical care unit?

    <p>Tight glucose control</p> Signup and view all the answers

    What was the impact of intensive glucose control on the risk of death in the NICE-SUGAR trial?

    <p>Increased risk</p> Signup and view all the answers

    Which country was the first major trial demonstrating the benefit of tight glucose control conducted in?

    <p>Belgium</p> Signup and view all the answers

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