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Questions and Answers
What is the primary function of a normally operating immune system?
What is the primary function of a normally operating immune system?
What distinguishes adaptive immunity from innate immunity?
What distinguishes adaptive immunity from innate immunity?
According to the provided text, which factor is primarily responsible for the specificity of the adaptive immune response?
According to the provided text, which factor is primarily responsible for the specificity of the adaptive immune response?
What does the term 'non-self' refer to within the context of the immune system?
What does the term 'non-self' refer to within the context of the immune system?
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How does the adaptive immune response react differently to a second exposure to the same antigen, compared to the first exposure?
How does the adaptive immune response react differently to a second exposure to the same antigen, compared to the first exposure?
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Which of the following is NOT considered a component of the innate immune system?
Which of the following is NOT considered a component of the innate immune system?
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What is required for adaptive immunity to initiate its response?
What is required for adaptive immunity to initiate its response?
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What is the role of bone marrow in the adaptive immune response?
What is the role of bone marrow in the adaptive immune response?
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What is the primary role of plasma cells in humoral immunity?
What is the primary role of plasma cells in humoral immunity?
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Where do T lymphocytes primarily mature?
Where do T lymphocytes primarily mature?
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What type of pathogens are primarily targeted by cell-mediated immunity?
What type of pathogens are primarily targeted by cell-mediated immunity?
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B cell maturation occurs in which of the following?
B cell maturation occurs in which of the following?
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Which specific proteins are produced by plasma cells?
Which specific proteins are produced by plasma cells?
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What is the primary way that the adaptive immunity type, known as Humoral immunity, attacks invaders?
What is the primary way that the adaptive immunity type, known as Humoral immunity, attacks invaders?
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Which type of immunity is developed by T lymphocytes?
Which type of immunity is developed by T lymphocytes?
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What distinguishes the targets of humoral immunity from those of cell-mediated immunity?
What distinguishes the targets of humoral immunity from those of cell-mediated immunity?
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Which of the following best describes the role of naïve B cells?
Which of the following best describes the role of naïve B cells?
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What is the primary function of CD8 cells when activated by an antigen fragment presented on an APC?
What is the primary function of CD8 cells when activated by an antigen fragment presented on an APC?
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What is the main function of antibodies produced by plasma cells?
What is the main function of antibodies produced by plasma cells?
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Which statement best describes the process of developing immunity through vaccination?
Which statement best describes the process of developing immunity through vaccination?
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Why are booster shots often needed after the initial vaccination?
Why are booster shots often needed after the initial vaccination?
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What is the typical implication if a patient has a negative antibody titer result?
What is the typical implication if a patient has a negative antibody titer result?
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Which of the following is NOT an example of an immediate form of passive immunity?
Which of the following is NOT an example of an immediate form of passive immunity?
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Which class of immunoglobulins primarily facilitates immune responses by directly binding to specific antigens?
Which class of immunoglobulins primarily facilitates immune responses by directly binding to specific antigens?
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Which type of cells are primarily utilized in cell-mediated immunity?
Which type of cells are primarily utilized in cell-mediated immunity?
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What is a key characteristic of active acquired immunity?
What is a key characteristic of active acquired immunity?
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Unlike humoral immunity, what characteristic is primarily associated with cell mediated immunity?
Unlike humoral immunity, what characteristic is primarily associated with cell mediated immunity?
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Which of the following is a defining trait of passive acquired immunity?
Which of the following is a defining trait of passive acquired immunity?
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Helper T cells play a crucial role in the immune response by:
Helper T cells play a crucial role in the immune response by:
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How is an antigen processed in active immunity?
How is an antigen processed in active immunity?
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In contrast to passive immunity, what is a primary characteristic of active immunity regarding the immune response?
In contrast to passive immunity, what is a primary characteristic of active immunity regarding the immune response?
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What sets apart cell-mediated immunity from humoral immunity?
What sets apart cell-mediated immunity from humoral immunity?
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What is the primary mode of action in passive immunity, as opposed to active immunity?
What is the primary mode of action in passive immunity, as opposed to active immunity?
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Flashcards
Immune System
Immune System
The body's complex defense mechanism that protects against harmful agents such as bacteria, viruses, and toxins.
Self vs. Non-self
Self vs. Non-self
The ability of the immune system to distinguish between the body's own cells and foreign substances.
Antigen
Antigen
Any substance that triggers an immune response. It can be a molecule, a protein, or a fragment of an invading organism.
Innate Immunity
Innate Immunity
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Adaptive Immunity
Adaptive Immunity
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Immunological Memory
Immunological Memory
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Lymphocytes
Lymphocytes
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Memory Response
Memory Response
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Humoral Immunity
Humoral Immunity
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Cell-mediated Immunity
Cell-mediated Immunity
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Naïve B Cell
Naïve B Cell
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B Cell Maturation
B Cell Maturation
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Antibodies
Antibodies
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Humoral Immunity: Purpose
Humoral Immunity: Purpose
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Cell-mediated Immunity: Purpose
Cell-mediated Immunity: Purpose
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T Cell Maturation
T Cell Maturation
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B Cell Maturation Location
B Cell Maturation Location
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T Cell Location
T Cell Location
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Antigen Presentation to CD8+ Cells
Antigen Presentation to CD8+ Cells
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Vaccine
Vaccine
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Booster
Booster
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Antibody Titer
Antibody Titer
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Immunoglobulins (Ig)
Immunoglobulins (Ig)
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IgG
IgG
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IgA
IgA
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IgE
IgE
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IgM
IgM
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IgD
IgD
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Active acquired immunity
Active acquired immunity
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Passive acquired immunity
Passive acquired immunity
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Antigen-Presenting Cell (APC)
Antigen-Presenting Cell (APC)
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Study Notes
The Immune System
- The immune system is a complex defense mechanism that protects the body from harmful agents.
- It distinguishes between "self" and "non-self" substances.
- "Non-self" substances are called antigens.
- A healthy immune system rapidly identifies antigens and activates defense mechanisms to eliminate the threat.
- A weakened immune system may not respond quickly.
Innate vs. Adaptive Immunity
- Innate Immunity:
- The body's first line of defense, providing immediate protection.
- Uses natural mechanisms like barriers (skin, mucous membranes), normal flora, white blood cells, enzymes, and chemicals.
- Includes natural killer cells for rapid response.
- Adaptive Immunity:
- Occurs after innate immunity.
- More specific in its targeting of antigens.
- Uses memory for quicker response to future exposures.
- Driven by lymphocytes (B and T cells).
Adaptive Immunity: Humoral Immunity
- Also known as B cell immunity.
- B cells mature in bone marrow, spleen, and lymph nodes.
- Protects against extracellular pathogens (outside cells).
- Circulates in the bloodstream.
- B cells become plasma cells which produce antibodies (immunoglobulins, Igs).
- Antibodies bind to and neutralize specific antigens.
- Igs include types like IgG, IgA, IgE, IgM, IgD.
- Helper T cells support the immune response.
Adaptive Immunity: Cell-Mediated Immunity
- Also known as T cell immunity.
- T cells mature in the thymus.
- Protects against intracellular pathogens (inside cells).
- Involves macrophages, T lymphocytes, and cytotoxic cells for pathogen destruction.
- Helper T cells (CD4+) help activate other cells.
- Cytotoxic T cells (CD8+) directly destroy infected cells or cancer cells.
Adaptive Immunity: Active vs. Passive
- Active Acquired:
- Obtained through exposure to an antigen or immunization (vaccine).
- The body synthesizes specific immunoglobulins (antibodies) against the antigen.
- Provides long-term immunity.
- Passive Acquired:
- Involves receiving pre-manufactured immunoglobulins.
- The body does not produce the antibodies; it passively receives them.
- Provides short-term immunity.
Immunizations and Boosters
- Vaccines contain weakened or inactivated viruses or components.
- Vaccines do not cause disease.
- Vaccines stimulate the body's immune response to produce antibodies against specific antigens.
- Booster shots are given later to maintain and strengthen immunity.
Antibody Titer
- Antibody titers are tests to measure antibody levels.
- Negative titers indicate a lack of immunity related to antibodies.
- High IgM levels may indicate a recent infection.
- Adequate IgG levels imply previous exposure.
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Description
Explore the complexities of the immune system, including its mechanisms and functions. This quiz covers both innate and adaptive immunity, highlighting the roles of white blood cells and lymphocytes. Test your understanding of how our body defends against harmful agents and the differences between immune responses.